
a16z Podcast
The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
Latest episodes

17 snips
Apr 26, 2024 • 31min
Next-Gen Gaming: AI Souls, Real-time Culture, Personalized Avatars
Dive into the future of gaming with insights on merging traditional play with digital innovation. Discover how AI is reshaping gameplay and storytelling, enhancing user engagement. The rise of user-generated content is empowering players to become creators, pushing the boundaries of interactive storytelling. Explore the ethical implications of conscious machines and how gaming plays a role in these discussions. This captivating conversation reveals how technology and creativity are revolutionizing the gaming landscape for the next generation.

Apr 22, 2024 • 25min
Why America Must Lead in AI Investment with Senator Young (R-IN)
Senator Todd Young, a U.S. senator from Indiana since 2016, teams up with Martin Casado, a General Partner at Andreessen Horowitz, to discuss America's pivotal role in AI advancement. They delve into the critical need for open innovation and strategic investment across various sectors. The conversation highlights the importance of bipartisan cooperation on AI regulation and the significance of the CHIPS Act in boosting tech resources. Young and Casado argue for a balanced integration of public and private funding to nurture advancements in AI and maintain U.S. leadership.

77 snips
Apr 17, 2024 • 41min
Game On: Marc Andreessen & Andrew Chen Talk Creative Computers
Explore how the gaming industry drives technological innovation with GPUs and AI, shaping future experiences. The discussion dives into generational gaming bonds and the educational value it brings. There's a look at the balance of government and private sector roles in tech regulation, and how social media can create a supportive space for founders. The evolving investment landscape emphasizes gaming as a long-term platform, merging entertainment with transformative potential across sectors like education and health.

22 snips
Apr 10, 2024 • 30min
Inside the Department of Defense and its Vision for the Future
Kathleen Hicks, the United States Deputy Secretary of Defense with extensive experience in defense policy, discusses vital military innovations and the deep ties between defense and technology. She highlights how the DoD is adapting to modern warfare through ethical AI practices and collaboration with the tech sector. The conversation touches on strategies for enhancing military readiness, the importance of reforming defense acquisition processes, and lessons learned from the Ukraine conflict, all while emphasizing a vision for responsible technological integration.

176 snips
Apr 5, 2024 • 1h 43min
Politics & the Future of Tech with Marc Andreessen and Ben Horowitz
In an engaging conversation, the hosts tackle the pressing issue of tech regulation and its impact on innovation. They explore the tensions between big tech monopolies and emerging startups, emphasizing the need for decentralized AI solutions. The duo discusses the importance of political involvement for tech companies, the contrasting philosophies of AI regulation in Europe and the UK, and the challenges of maintaining a competitive landscape. They also touch on the American Dream and the disillusionment faced by younger generations amidst rising costs.

28 snips
Mar 29, 2024 • 26min
The Real Price of Healthcare with Mark Cuban
Mark Cuban, renowned entrepreneur and Dallas Mavericks owner, dives into the complexities of the healthcare industry. He discusses his venture, Cost Plus Drugs, aimed at revolutionizing prescription drug pricing through transparency and eliminating middlemen. Cuban emphasizes the challenges faced by innovative healthcare startups and critiques the traditional education system, advocating for practical skills over elite degrees. He celebrates the entrepreneurial spirit in America, stressing its role in maintaining innovation and the American dream.

36 snips
Mar 25, 2024 • 25min
Devoting Your Life to Reinventing a Broken System
In this engaging discussion, Ed Park, Co-founder of Devoted Health, shares his mission to revolutionize healthcare through technology. He, alongside his brother Todd, emphasizes the urgent need for reform in a deeply flawed system, particularly for older Americans. They recount their entrepreneurial journeys and experiences with Athena Health, highlighting the role of AI in improving patient care. With personal anecdotes and insights into their immigrant backgrounds, they inspire listeners about the potential for tech-driven solutions to reshape healthcare.

109 snips
Mar 20, 2024 • 28min
Bringing AI to the Masses with Adam D’Angelo
Adam D’Angelo, CEO and founder of Quora and AI aggregator Poe, dives into the revolutionary impact of generative AI on our world. He discusses how Poe aims to democratize AI access, making it easier for creators and researchers. D'Angelo highlights the synergy between humans and AI, as well as the importance of experimentation in this evolving field. He also reflects on the transformative power of tailored AI solutions and the strategic shifts organizations need to make in response to this AI-driven landscape.

42 snips
Mar 15, 2024 • 48min
A Nuclear Comeback: Are New Reactors the Answer?
Join David Ulevich, a General Partner at Andreessen Horowitz, Doug Bernauer, CEO of Radiant, and Dr. Kathryn Huff, Assistant Secretary of Nuclear Energy, as they explore the nuclear energy renaissance in the U.S. They discuss the groundbreaking advancements in portable microreactors and the impact of new policies on the industry's future. The conversation highlights nuclear power's role in energy security amidst climate challenges and emphasizes the collaboration between private innovation and government initiatives to revitalize nuclear energy for a cleaner, sustainable future.

76 snips
Mar 11, 2024 • 47min
Intelligence in the Age of AI with new CTO of the CIA
Nand Mulchandani, the CIA's first-ever CTO, dives into AI's revolutionary impact on intelligence and national security. He discusses how analysts can adapt their skills to work alongside AI, emphasizing human judgment in decision-making. The conversation touches on the transformation of intelligence operations through technology and stresses the need for public-private partnerships to harness AI effectively. Unpacking challenges like AI's limitations and biases, Mulchandani highlights the urgency for governmental adaptation to stay ahead in the tech-driven landscape.
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