JAMAevidence JAMA Guide to Statistics and Methods
Interviews with authors of JAMA Guide to Statistics and Methods chapters about common and new statistics and methods used in clinical research and reported in medical journals.
Latest episodes
Dec 3, 2020 • 23min
Randomization in Clinical Trials from the JAMA Guide to Statistics and Methods
Roger J. Lewis, MD, PhD, discusses Randomization in Clinical Trials from the JAMA Guide to Statistics and Methods Related Article(s): Randomization in Clinical Trials
Sep 3, 2020 • 18min
The Stepped-Wedge Clinical Trial: Evaluation by Rolling Deployment
Cluster randomized trials are performed when an intervention must be delivered to a group of patients like when testing new nursing protocols on award or different means for cleaning beds on a ward. One type of cluster trials is called a stepped-wedge where every cluster in the study ultimately undergoes the intervention. How this works it is explained by Susan Ellenberg, PhD, from the Department of Biostatistics, Epidemiology, and Informatics at the University of Pennsylvania School of Medicine. Related Article: The Stepped-Wedge Clinical Trial
Aug 6, 2020 • 12min
Minimal Clinically Important Difference: Defining What Really Matters to Patients
JAMA Deputy Editor Edward Livingston, MD, discusses Minimal Clinically Important Difference: Defining What Really Matters to Patients with Anna E. McGlothlin, PhD
Jul 2, 2020 • 12min
Sample Size Calculation for a Hypothesis Test With Dr Lynne Stokes
One of the most common causes for problems we see in manuscripts at JAMA is an inappropriately calculated study sample size. This seemingly mysterious process is explained by Lynne Stokes, PhD, professor of Statistical Science at Southern Methodist University in Dallas, Texas.
Jun 25, 2020 • 21min
Pragmatic Trials: Practical Answers to “Real-world” Questions With Harold C. Sox, MD
JAMA Deputy Editor Edward Livingston, MD, discusses Pragmatic Trials: Practical Answers to “Real-world” Questions with Harold C. Sox, MD, of PCORI
May 7, 2020 • 24min
Cluster Randomized Trials: Evaluating Treatments Applied to Groups With William J. Meurer, MD
JAMA Deputy Editor Edward Livingston, MD, discusses "Cluster Randomized Trials: Evaluating Treatments Applied to Groups" with William J. Meurer, MD, MS
Feb 6, 2020 • 11min
Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Dr Amy Kaji
Dr. Amy Kaji, an MD, PhD specializing in Noninferiority Trials, discusses concepts such as minimal clinically important difference, one-way vs two-way statistical tests, and the differences between noninferiority and superiority trials. The importance of selecting the minimally important clinical difference and sample size for trials is also emphasized.
Dec 5, 2019 • 14min
JAMA Guide to Statistics and Methods
Clinical researchers and biostatisticians use highly specialized language to help them discuss statistics and research methods efficiently. In 2019 JAMA published the JAMA Guide to Statistics and Methods, a book of short reviews that translate that specialized language and explain statistics and methods to a broad physician readership. The book's editors and authors, Edward Livingston, MD, and Roger J. Lewis, MD, PhD, discuss their approach to choosing statistical topics and their objectives in compiling the reviews into book format. Purchase the JAMA Guide to Statistics and Methods at: McGraw-Hill: ja.ma/StatsGuideMH Barnes and Noble: ja.ma/StatsGuideBN Amazon: ja.ma/StatsGuideAmazon
