JAMA Deputy Editor Edward Livingston, MD, discusses Pragmatic Trials: Practical Answers to “Real-world” Questions with Harold C. Sox, MD, of PCORI

JAMA Deputy Editor Edward Livingston, MD, discusses "Cluster Randomized Trials: Evaluating Treatments Applied to Groups" with William J. Meurer, MD, MS

Dr. Amy Kaji, an MD, PhD specializing in Noninferiority Trials, discusses concepts such as minimal clinically important difference, one-way vs two-way statistical tests, and the differences between noninferiority and superiority trials. The importance of selecting the minimally important clinical difference and sample size for trials is also emphasized.

Clinical researchers and biostatisticians use highly specialized language to help them discuss statistics and research methods efficiently. In 2019 JAMA published the JAMA Guide to Statistics and Methods, a book of short reviews that translate that specialized language and explain statistics and methods to a broad physician readership. The book's editors and authors, Edward Livingston, MD, and Roger J. Lewis, MD, PhD, discuss their approach to choosing statistical topics and their objectives in compiling the reviews into book format.   Purchase the JAMA Guide to Statistics and Methods at: McGraw-Hill:                    ja.ma/StatsGuideMH Barnes and Noble:           ja.ma/StatsGuideBN Amazon:                            ja.ma/StatsGuideAmazon