Osterholm Update

<p>In "An Unfolding Saga," Dr. Osterholm and Chris Dall discuss the latest H5N1, COVID-19, and measles news. Dr. Osterholm also answers an ID query on influenza and shares the latest "This Week in Public Health History" segment.&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/avian-influenza-bird-flu/study-confirms-infection-mice-fed-h5n1-contaminated-raw-milk">Study confirms infection in mice fed H5N1-contaminated raw milk</a> (CIDRAP News)</p> <p><a href="https://erictopol.substack.com/p/akiko-iwasaki-the-immunology-of-covid">Akiko Iwasaki &amp; Eric Topol Interview: The Immunology of Covid and the Future</a> (Ground Truths)</p> <p><a href="https://www.cidrap.umn.edu/newsletter">Sign up for CIDRAP's daily newsletter</a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19">MORE EPISODES</a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap">SUPPORT THIS PODCAST</a></p>

<p>In "Lungs &amp; Udders," Dr. Osterholm provides updates on H5N1 influenza, COVID-19, and mpox. He also shares his thoughts on a recent WHO report about airborne transmission and a study on the use of a diabetes drug to treat COVID-19.</p> <p><a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00244-7/fulltext">Airborne pathogens: controlling words won’t control transmission</a> (Greenhalgh et al., <em>The Lancet</em>)</p> <p><a href="https://www.cidrap.umn.edu/newsletter">Sign up for CIDRAP's daily newsletter</a></p> <p><a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19">MORE EPISODES</a>&nbsp; &nbsp; &nbsp;&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/support-cidrap">SUPPORT THIS PODCAST</a></p>

<p>In "H5N1: An Impending Crisis," Dr. Osterholm and Chris Dall discuss the spread of H5N1 avian influenza in US<br>dairy cows, cover the latest COVID-19 trends, review two articles on long COVID, and answers a listener question about the safety of raw milk and other dairy products. Dr. Osterholm also shares a timely "This Week in Public Health History" segment and interviews the final two members of the podcast team.</p> <p>&nbsp;</p> <p><a href="https://www.statnews.com/2024/04/25/h5n1-bird-flu-cows-outbreak-likely-widespread/">Early tests of H5N1 prevalence in milk suggest U.S. bird flu outbreak in cows is widespread</a> (<em>STAT, subscription may be required</em>)</p> <p><a href="https://www.statnews.com/2024/04/24/h5n1-bird-flu-vaccine-preparedness/">Massive amounts of H5N1 vaccine would be needed if there’s a bird flu pandemic. Can we make enough?</a> (<em>STAT, subscription may be required</em>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/long-covid-patients-more-likely-report-psychiatric-symptoms-cost-barriers-therapy">Long-COVID patients more likely to report psychiatric symptoms, cost barriers to therapy</a> (<em>CIDRAP News</em>)</p> <p><a href="https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00171-3/fulltext">The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China</a> (<em>Lancet Infectious Diseases</em>)</p> <p>&nbsp;</p> <p><a href="https://www.cidrap.umn.edu/newsletter">Sign up for CIDRAP's daily newsletter</a></p> <p><a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/superbugs-you">Superbugs &amp; You podcast</a></p> <p><a href="https://www.cidrap.umn.edu/osterholm-update">More episodes</a></p> <p><a href="cidrap.umn.edu/support">Support this podcast</a></p> <ul>&nbsp;</ul>

<p>In "Brighter Days Ahead," Dr. Osterholm and Chris Dall discuss the latest national and international COVID trends, recent research on long COVID, and measles cases in the U.S. Dr. Osterholm also shares the latest "This Week in Public Health History" segment and interviews two members of the podcast team.</p> <p>Please fill out our <a href="https://redcap.ahc.umn.edu/redcap/surveys/?s=DKAXDYKTDXCN4HLT">Listener Feedback Survey</a>!</p> <p><a href="https://www.cidrap.umn.edu/covid-19/three-studies-spotlight-long-term-burden-covid-us-adults">Three studies spotlight long-term burden of COVID in US adults</a> (Van Beusekom, <em>CIDRAP News</em>)</p> <p><a href="https://www.science.org/content/article/long-covid-trials-aim-clear-lingering-virus-help-patients-need">Lessons in persistence: new long COVID trials aim to clear lingering virus—and help patients in dire need</a> (Couzin-Frankel, <em>Science</em>)</p> <p><a href="https://www.economist.com/graphic-detail/coronavirus-excess-deaths-estimates">The pandemic’s true death toll</a> (<em>The Economist</em>)</p> <p><a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/superbugs-you">Superbugs &amp; You podcast</a></p> <p><a href="https://www.cidrap.umn.edu/osterholm-update">More episodes</a></p> <p><a href="cidrap.umn.edu/support">Support this podcast</a></p> <ul>&nbsp;</ul>

<p>In "H5N1 Uncertainty," Dr. Osterholm and Chris Dall discuss the latest national COVID trends, a recent study on Paxlovid, and H5N1 avian flu virus infection in cattle. Dr. Osterholm also shares the latest "This Week in Public Health History" segment and interviews two members of the podcast team.</p> <p>Please fill out our <a href="https://redcap.ahc.umn.edu/redcap/surveys/?s=DKAXDYKTDXCN4HLT">Listener Feedback Survey</a>!</p> <p><a href="https://www.cidrap.umn.edu/covid-19/swedish-study-suggests-link-between-long-covid-and-severity-illness">Swedish study suggests link between long COVID and severity of illness</a>&nbsp;(Stephanie Soucheray,&nbsp;<em>CIDRAP News</em>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/study-long-covid-affects-8-those-covid-19-more-common-women">Study: long COVID affects 8% of those with COVID-19, is more common in women</a> (Stephanie Soucheray,&nbsp;<em>CIDRAP News</em>)</p> <p><a href="https://www.cidrap.umn.edu/covid-19/new-neurologic-issues-less-likely-after-severe-covid-flu-research-suggests">New neurologic issues less likely after severe COVID than flu, research suggests</a> (Mary Van Beusekom,&nbsp;<em>CIDRAP News</em>)</p> <p><a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2309003">Nirmatrelvir for vaccinated or unvaccinated adult outpatients with COVID-19</a> (Hammond et al.,&nbsp;<em>New England Journal of Medicine</em>)</p> <p><a href="https://www.nejm.org/doi/full/10.1056/NEJMe2402224">Treating acute COVID-19 — final chapters still unwritten</a> (Gandhi &amp; Hirsch,&nbsp;<em>New England Journal of Medicine</em>)</p> <p><a href="https://www.cidrap.umn.edu/osterholm-update">More episodes</a></p> <p><a href="cidrap.umn.edu/support">Support this podcast</a></p>

<p>In "Good News in a COVID-Indifferent World," Dr. Osterholm and Chris Dall discuss the national and international COVID trends, the latest research on long COVID, and antibiotic-resistant <em>Shigella</em>. Dr. Osterholm also shares the latest "This Week in Public Health History" segment and interviews members of the podcast team.&nbsp;</p> <ul> <a href="https://doi.org/10.1038/s41590-024-01754-8">Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19</a> (Hanson et al.,&nbsp;<em>Nature Immunology</em>)<br> <a href="https://www.pewresearch.org/science/2024/03/07/how-americans-view-the-coronavirus-covid-19-vaccines-amid-declining-levels-of-concern/">How Americans view the coronavirus, COVID-19 vaccines amid declining levels of concern</a> (Tyson &amp; Pasquini,&nbsp;<em>Pew Research Center</em>)<br> <a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/spike-extensively-drug-resistant-shigella-cases-reported-uk-europe">Spike in extensively drug-resistant Shigella cases reported in UK, Europe</a> (Dall,&nbsp;<em>CIDRAP News</em>)<br> <a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/cdc-warns-increase-extensively-drug-resistant-shigellosis">CDC warns of increase in extensively drug-resistant shigellosis</a> (Dall,&nbsp;<em>CIDRAP News</em>)<br> <a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/superbugs-you">Superbugs &amp; You podcast</a> — new episode&nbsp;coming 3/26!<br> <a href="https://www.theguardian.com/society/2020/may/26/last-iron-lung-paul-alexander-polio-coronavirus">The man in the iron lung</a> (McRobbie, <em>The Guardian</em>)<br> <a href="https://www.cidrap.umn.edu/osterholm-update">More episodes</a><br> <a href="cidrap.umn.edu/support">Support this podcast</a> </ul>

Dr. Osterholm discusses new CDC COVID isolation guidelines, a measles outbreak in Florida, avian influenza news, and updates on influenza and RSV cases in the U.S. He stresses the importance of accurate information during the pandemic and shares insights into public health history.

<p>In this episode, Dr. Osterholm and Chris Dall discuss COVID isolation guidelines, the BA.2.87.1 variant, and the importance of measles and other rare public health threats.&nbsp;</p>

<p>In "A Family Discussion," Dr. Osterholm and Chris Dall discuss the latest SARS-CoV-2 variant, consider the current and future challenges accessing Paxlovid, and explore new long COVID research. Dr. Osterholm also revisits last episode's discussion on changing public health guidelines and celebrates some canine heroes in the "This Week in Public Health History" segment.&nbsp;</p> <ul> <a href="https://www.pnas.org/doi/10.1073/pnas.2300644120">Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes</a> (Yue Zhang,&nbsp;<em>PNAS</em>)<br> <a href="https://www.startribune.com/minnesota-hospitals-say-65000-days-of-care-were-avoidable-if-patients-had-somewhere-to-go/600340025/">Minnesota hospitals say 65,000 days of care were avoidable if patients had somewhere to go</a>&nbsp;(Jeremy Olson,&nbsp;<em>Star Tribune</em>)<br> <a href="https://www.health.state.mn.us/diseases/coronavirus/paxrx.pdf">Have a Paxlovid Prescription? Low Cost Options Available</a> (Minnesota Department of Health)<br> <a href="https://treatments.hhs.gov/">Find COVID-19 Medications</a> (Administration for Strategic Preparedness and Response, HHS)<br> <a href="https://www.washingtonpost.com/lifestyle/2024/01/31/shelter-dog-rescue-homeless-fayetteville/">Homeless man leaves puppies at N.C. shelter with heart-tugging note</a> (Cathy Free,&nbsp;<em>Washington Post</em>) </ul>

<p>In "A Period of Transition," Dr. Osterholm and Chris Dall discuss the latest COVID-19 trends in the U.S. and around the world, a recent study on long COVID, and the rise of measles cases in the United States. Dr. Osterholm also provides an update on influenza and RSV cases in the U.S. and shares the latest "This Week in Public Health History" segment.&nbsp;</p> <ul> <a href="https://www.science.org/doi/10.1126/science.adg7942">Persistent complement dysregulation with signs of thromboinflammation in active long COVID</a> (Cervia-Hasler et al.,&nbsp;<em>Science</em>)<br> <a href="https://erictopol.substack.com/p/lighting-up-long-covid">Lighting up long COVID</a> (Eric Topol,&nbsp;<em>Ground Truths</em>)<br> <a href="http://tinyurl.com/LCEditorial">Follow up, funding critical on long COVID</a> (Jill Burcum,&nbsp;<em>Star Tribune</em>)<br> <a href="https://www.cidrap.umn.edu/covid-19/does-paxlovid-prevent-long-covid-maybe-experts-suggest">Does Paxlovid prevent long COVID? Maybe, experts suggest</a> (Stephanie Soucheray,&nbsp;<em>CIDRAP News</em>) </ul>