Baiba Braže, the Latvian Foreign Minister, discusses the pressing security threats to the Baltics from Russia, including cyberattacks and hybrid warfare. She emphasizes the need for heightened defense spending amid rising instability. Dmitri Trenin, a former Russian colonel, offers a contrasting perspective, asserting that decisions about Ukraine should rest with Russia and the U.S., rather than Ukraine itself. Both guests highlight the evolving geopolitical landscape and the urgent need for diverse viewpoints in addressing security challenges in Europe.

Elissa Slotkin, a former CIA analyst and current U.S. Senator, joins Alina Polyakova, the President of the Center for European Policy Analysis, to discuss pressing issues in European security. They analyze the repercussions of Trump's call with Putin and how it affects U.S.-Europe relations. The conversation dives into NATO allies' concerns about American support and the challenges in ensuring Ukraine's security amid shifting geopolitical dynamics. They also touch on the need for European nations to bolster their defense capabilities in a potentially isolated landscape.

Riyad Mansour, the Palestinian Ambassador to the UN, shares his insights on the Israeli-Palestinian conflict and the future of Gaza. He critiques Trump's controversial proposal for Gaza, emphasizing its implications on Palestinian identity and historical displacement. Mansour passionately defends the Palestinians' deep-rooted connection to their land, rejecting any notion of forced relocation. He also warns against efforts to erase Palestinian identity, questioning whether Gaza's future will be decided by its people or global powers.

Apoorva Mandavilli, a New York Times science and global health reporter, discusses the dramatic shifts in U.S. public health policy during the Trump administration. She delves into the controversial nomination of RFK Jr. and the deepening vaccine skepticism in America. Mandavilli explores the implications of withdrawing from the WHO and the challenges of public trust in health messaging. With rising concerns about future pandemics, she highlights a crucial need for reform in health institutions like the CDC and NIH, questioning whether these changes are corrections or risks.

Former Finnish Prime Minister Alexander Stubb offers keen insights on the shift in U.S.-Europe relations following Trump's second term. He discusses Europe's need to adapt its security strategies amid increasing geopolitical tensions and the ongoing war in Ukraine. Stubb highlights the importance of leveraging technology to enhance transatlantic collaboration and addresses the rising influence of tech figures on European politics. Additionally, he advocates for a return to cooperative multilateralism to face the chaos of the current international order, emphasizing democratic resilience.

Nicholas Thompson, CEO of The Atlantic and former editor-in-chief of Wired, discusses the crossroads of technology and politics. He examines how a potential Trump 2.0 administration might loosen AI regulations and reshape the tech landscape. Thompson highlights the shifting dynamics between Big Tech and political influence, along with the implications of AI on human interactions. He also delves into Elon Musk's role in media and public discourse, questioning how these changes will affect democracy and information integrity in America.

Francis Fukuyama, a prominent political scientist from Stanford, joins the discussion to analyze the impending G-Zero world of 2025. He emphasizes the dangers of a leaderless global landscape, where power dynamics could devolve into chaos. Fukuyama highlights the importance of fostering trust among leaders amidst rising tensions with China and evolving alliances, such as Russia's partnerships with North Korea and Iran. He also critiques the erosion of liberal democracy in the U.S. and the prioritization of results over procedural norms in modern politics.

Cliff Kupchan, Chairman of Eurasia Group, and Susan Glasser, New Yorker staff writer, dive into the geopolitical landscape of 2025. They discuss the potential fallout from the Trump administration's policies and the shifting power dynamics involving China and Russia. The conversation uncovers the risks of U.S.-China relations, economic tensions, and the rise of authoritarianism. With insights on global instability, nuclear ambitions in Iran, and the implications of artificial intelligence, this dialogue offers a thought-provoking look at an uncertain future.

Jake Sullivan, the outgoing US National Security Advisor, reflects on his pivotal role in shaping foreign policy during Biden’s administration. He discusses the rapid shifts in the Middle East, particularly in relation to Israel and Iran, and emphasizes the importance of continuity amid presidential transitions. Sullivan addresses the challenges posed by U.S.-China relations and the need for collaboration on global issues like technology and security. He warns that geopolitical vacuums can empower adversaries, urging a unified message in turbulent times.

Kim Ghattas, a Beirut-based journalist and Middle East expert, dives into the recent collapse of the Assad regime in Syria. She discusses the rapid unravelling of an authoritarian rule that lasted decades, shedding light on the staggering human cost of the conflict. Ghattas examines the complex geopolitical landscape, highlighting how Iran, Russia, and Israel are maneuvering for influence in the vacuum left behind. She also emphasizes the importance of a Syrian-led transition and the critical role of U.S. foreign policy in ensuring stability in the region.