Matt Maiocco and Jennifer Lee Chan break down the 49ers’ second-half collapse in their 24-23 home loss to the Arizona Cardinals. They analyze how Christian McCaffrey’s injury absence has led to San Francisco’s red-zone issues and how concerning the 49ers’ 2-3 start to the season has been.4:00 Has CMC's absence led to 49ers' red-zone struggles?10:00 Did heat play a part in second-half collapse?22:30 How short week could be blessing in disguise for 49ers28:15 Brandon Aiyuk's big game was bright spot33:00 Why 49ers haven't been able to shut door on opponents

Greg Papa sits down with Kyle Shanahan to look ahead to the 49ers' matchup against the Arizona Cardinals and discuss Jauan Jennings, Fred Warner, and how San Francisco can contain Kyler Murray. Also, Matt Maiocco and Carlos Ramirez discuss Brock Purdy's evolution as a leader.

Matt Maiocco sits down with Patrick Willis to discuss his upcoming Pro Football Hall of Fame ring ceremony and why he believes Fred Warner is the best player in the NFL. Also, Matt talks to Jennifer Lee Chan and Greg Papa to preview Sunday’s matchup against Kyler Murray and the Arizona Cardinals.1:30 Warm weather expected vs. Cardinals6:45 49ers injury update22:25 Previewing game vs. Cardinals35:20 Papa details how 49ers will defend Murray39:00 Is Deommodore Lenoir the 49ers’ third-best player on defense?48:30 Willis looks forward to Hall of Fame ring ceremony53:45 Willis explains why Warner is NFL’s best player

Matt Maiocco and Jennifer Lee Chan break down the 49ers’ 30-13 bounce-back win over the Patriots, highlighted by spectacular plays from Fred Warner and George Kittle. Matt and Jennifer also analyze QB Brock Purdy’s performance and point out contributions from some unheralded members of the 49ers’ defense.1:00 Warner, Kittle provide highlight-reel plays in 49ers' win5:30 49ers' defense receives boost from Kevin Givens, Maliek Collins, Sam Okuayinonu11:30 Are NFL defenses figuring out Purdy, 49ers' offense?17:15 Isaac Guerendo fumbles as special-teams miscues continue28:30 How Ricky Pearsall can bring different element to 49ers' offense31:30 What to make of Brandon Aiyuk being asked to change his shorts at practice

Greg Papa sits down with Kyle Shanahan to look ahead to the 49ers' matchup against the Patriots and discuss Brock Purdy's evolution, how Jauan Jennings consistently gets separation, and how San Francisco can get it's season back on track against New England. Also, Matt Maiocco and Carlos Ramirez discuss who's to blame for the defensive struggles.

Matt Maiocco and Jennifer Lee Chan analyze how the 49ers’ defense can move forward after losing Javon Hargrave for the season and explain why it’s not time to panic despite the mounting injuries. Also, Matt sits down with Greg Papa to discuss how the Patriots could attack the 49ers on Sunday, and checks in with NBC Sports Boston’s Tom Curran for a full New England scouting report.6:00 How 49ers can move forward without Hargrave18:00 Can Brock Purdy, Jauan Jennings replicate connection vs. Patriots24:45 Why it's not time for 49ers to panic32:30 Greg Papa analyzes 49ers' defense39:45 Papa details how New England could attack 49ers45:45 Tom Curran discusses Purdy's performance vs. Rams50:45 Curran provides Patriots scouting report54:45 Predictions for 49ers-Patriots game

Matt Maiocco and Jennifer Lee Chan analyze how the 49ers blew a 10-point fourth-quarter lead to the short-handed Rams in Week 3. Matt and Jennifer detail the special-teams miscues and defensive breakdowns that led to the stunning defeat despite Jauan Jennings’ career-best three-touchdown day.0:45 What to make of 49ers' ugly, disastrous loss to Rams2:30 Rams exploit 49ers' special-teams miscues5:30 Brandon Aiyuk didn't step up in offensive stars' absence10:30 Why wasn't Week 2 loss to Vikings an eye opener?14:00 How much blame should Kyle Shanahan receive for back-to-back sloppy games?23:30 Analyzing Jennings' big performance27:30 Breaking down 49ers defense's struggles past two weeks

Greg Papa sits down with Kyle Shanahan to look ahead to the 49ers' matchup against the Los Angeles Rams and how San Francisco's offense will adjust without Christian McCaffrey and Deebo Samuel. Also, Jennifer Lee Chan and Carlos Ramirez discuss why Brock Purdy will be the key to a 49ers' victory on Sunday.

Matt Maiocco and Jennifer Lee Chan look ahead to the 49ers’ Week 3 matchup with the Rams and how Deebo Samuel’s absence will force Brandon Aiyuk to shoulder a larger load at wide receiver. Also, Matt sits down with Greg Papa to discuss what to expect in safety Talanoa Hufanga’s return.1:00 Previewing the 49ers-Rams matchup8:30 How Brandon Aiyuk can get back on track vs. Rams14:45 Talanoa Hufanga set to return21:00 49ers fans to takeover Sofi Stadium again38:00 Greg Papa analyzes Aiyuk's performances47:00 Papa shares what to expect from Hufanga

Matt Maiocco and Jennifer Lee Chan dissect the 49ers’ poor performance in the team's 23-17 loss to the Vikings where San Francisco made errors on offense, defense and special teams. Matt and Jennifer also highlight Fred Warner’s strong start to the season, and discuss the long-term impact of Christian McCaffrey’s injuries.2:00 49ers could have been blown out if not for Fred Warner8:00 Dissecting 49ers' offensive struggles10:45 Defensive breakdowns allow pair of Sam Darnold TDs16:30 Ricky Pearsall seen catching and throwing passes on sideline25:30 Analyzing poor special teams performance34:30 Brock Purdy and Brandon Aiyuk rhythm still off to start season