

Thyroid Pharmacist Healing Conversations with Dr. Izabella Wentz
Dr. Izabella Wentz
Welcome to Thyroid Pharmacist Healing Conversations, where Dr. Izabella Wentz, pharmacist, researcher and NYT bestselling author dives deep into the root causes of thyroid dysfunction, gut imbalances, fatigue, chronic health issues and autoimmunity. This show brings you deep, insightful conversations with top experts in functional medicine, nutrition, and wellness. We explore topics like gut health, adrenal support, detoxification, diet, and lifestyle changes to help you take control of your health and reclaim your energy. Join Dr. Wentz for solo episodes packed with practical strategies and insightful discussions from her own research and observations. Whether you're navigating Hashimoto’s, hypothyroidism, perimenopause, IBS, struggling with mystery symptoms, metabolism, or looking for holistic ways to optimize your well-being, these conversations will empower you with knowledge and actionable steps.Subscribe now to start your healing journey and discover the tools to thrive.
Episodes
Mentioned books

Oct 27, 2025 • 1h 35min
69: The Anti-Elimination Approach to Gut Healing with Steven Wright
In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz interviews gut health expert Steven Wright, founder of Healthy Gut. Steven shares his 15-year healing journey and explains why restrictive elimination diets often fail to resolve the root causes of digestive distress. Together, they explore how low stomach acid, SIBO, histamine overload, and stress contribute to food sensitivities – and how to build a more resilient gut that allows for food freedom.
What you’ll learn in this episode:
Why endless food elimination often backfires. While cutting out certain foods can help in the short term, staying overly restrictive can harm the microbiome, create nutrient deficiencies, and worsen food reactions over time. Healing requires more than just “the perfect diet.”
The overlooked role of stomach acid in gut health. Low stomach acid is common in people with Hashimoto’s and can drive SIBO, reflux, nutrient deficiencies, and ongoing inflammation. Steven explains how simple HCl support can restore digestion, energy, and overall resilience.
How histamine intolerance fuels food sensitivities. Symptoms like headaches, rashes, diarrhea, anxiety, or migraines can stem from histamine overload. Steven and Dr. Wentz discuss how mast cells, DAO enzymes, and butyrate help calm inflammation and support histamine tolerance.
Why probiotics and prebiotics aren’t enough on their own. A healthy gut requires proper digestion, enzymes, and microbial balance. Butyrate and brush border enzymes may be the missing link in rebuilding tolerance to plants and fibers.
Stress, the nervous system, and digestion. Even a perfect diet and supplements won’t work if you’re stuck in “fight-or-flight” mode. Discover practical ways to support your parasympathetic nervous system and adrenals, so your body can be in a state of healing.
Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode! Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/
For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Oct 24, 2025 • 1h 7min
68: Remission of SIBO, Crohns, IBS and IBD in Just Weeks with Debbie Steinbock
In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz interviews certified holistic nutrition counselor Debbie Steinbock about the elemental diet – a powerful but often overlooked tool for healing thyroid-related gut imbalances and SIBO, IBS, and IBD. Debbie shares her personal healing journey from Crohn’s disease, her clinical experience guiding clients with complex autoimmune conditions, and why the elemental diet can succeed where other protocols fall short.
Together, they explore how elemental diets feed the body while starving bacterial overgrowth, the pros and cons of different formulas, and how to avoid common mistakes that cause setbacks. Debbie also introduces her Elemental Diet Success Plan, a step-by-step roadmap to help people use this therapy with clarity and confidence.
What you’ll learn in this episode:
The connection between gut and thyroid health. Many people with hypothyroidism may also have SIBO (up to 50%), and motility issues tied to thyroid disease can fuel bacterial overgrowth. The elemental diet offers a way to reset both digestion and immune reactivity.
The elemental diet explained. Debbie breaks down what’s actually in an elemental shake, why it’s considered “pre-digested,” and how it feeds the body while giving the gut time to rest and heal.
Why SIBO and IBS are so stubborn. Many protocols fail because they either don’t fully eradicate bacterial overgrowth or they overwhelm a sensitive gut. Debbie explains why the elemental diet can be more effective, with research showing that the majority of people who try it find success in a matter of weeks.
Partial vs. full elemental diets. Not everyone needs to do a 100% liquid diet. Debbie describes how partial approaches – paired with “soft, warm, and mushy” foods – can calm flare-ups and support long-term remission for conditions like IBD.
Practical tips and side effects to expect. From energy swings and hunger to oral discomfort, Debbie shares what to watch for, how to prepare, and the strategies she teaches in her Elemental Diet Success Plan to minimize setbacks.
Why personalization matters. Not all formulas are created equal, and not all patients need the same approach. Debbie shares how to choose between amino-based and semi-elemental shakes, and when each might be best.
Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode! Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/
For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Oct 20, 2025 • 1h 4min
67: Overcoming Thyroid Hair Loss and When to Reintroduce Gluten With Dietitian Nataliia Sanzo
In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz speaks with registered dietitian Nataliia Sanzo about practical ways to calm the immune system through the gut, address common hair loss drivers in Hashimoto’s, and reintroduce foods safely after an elimination diet. They discuss the stool test markers that matter most (including intestinal permeability and H. pylori), the often-overlooked roles of blood sugar and bile flow, and how targeted nutrients can support healing.
What you’ll learn:
Gut health is central to autoimmunity. About 70% of the immune system lives in the gut. When the intestinal lining is irritated or “leaky,” the immune system stays on high alert, which can worsen thyroid symptoms. Nataliia shares which stool test markers matter most, such as short-chain fatty acids and signs of infections (like H. pylori), and how addressing them can help you shape your health plan.
A good stool test saves guesswork. Beyond identifying infections, tests can show whether you’re making enough digestive enzymes or butyrate, and whether bile flow needs support. With that information, you can start with a focused protocol (diet and a few well-chosen supplements), see early improvements, and then transition to food-first maintenance.
Food freedom is possible after elimination diets: With gut repair and nutrient repletion, Nataliia shares her step-by-step method for reintroducing foods safely and avoiding unnecessary long-term restriction.
Hair loss has common, fixable drivers. Low free-T3, low ferritin (Nataliia aims for ferritin ≥70 ng/mL), zinc/selenium/B-vitamin gaps, high stress hormones, and gut infections are frequent contributors. Supporting T4-to-T3 conversion (through gut and liver care, and in some cases with T3-containing medication), replenishing iron stores, and calming inflammation can make a real difference.
Blood sugar and bile flow quietly shape symptoms. Frequent spikes in blood sugar can increase inflammation and reduce T3 activation. Simple steps, such as a protein-forward plate and a 10-minute walk after meals, often help quickly. On the digestion side, healthy bile flow supports fat digestion and absorption of vitamins A, D, E, and K, and helps clear hormone byproducts.
Why H. pylori deserves attention: Nataliia shares why this common infection often lingers unnoticed, driving histamine symptoms, food sensitivities, and even hair loss, and the treatment options that can make a profound difference.
Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode! Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/
For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Oct 17, 2025 • 23min
66: The Gut-Thyroid Connection: Uncovering the Root Causes of Intestinal Permeability | Dr. Izabella Wentz
In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz explores the science behind intestinal permeability (leaky gut), a critical factor in both Hashimoto’s and irritable bowel syndrome. Drawing from her own story and over a decade of clinical research, she shares how healing the gut can lower thyroid antibodies, improve symptoms, and even bring autoimmune conditions into remission.
What you’ll learn in this episode:
Why intestinal permeability is central to autoimmunity. Dr. Alessio Fasano’s “three-legged stool” theory shows that while we can’t change our genes and don’t always know our exact triggers, we can heal intestinal permeability – often reducing inflammation and lowering thyroid antibodies. Dr. Wentz shares steps that can strengthen your gut lining and calm immune reactivity.
Leaky gut often shows up before an autoimmune diagnosis. IBS symptoms frequently appear 5 to 15 years before Hashimoto’s or other autoimmune conditions. Digestive pain, reflux, or bloating may be early warning signs, but intestinal permeability can also exist without gut symptoms. Discover how to recognize these early patterns and begin restoring balance before autoimmunity progresses.
Food sensitivities play a big role. Gluten and dairy are the most common culprits, but soy, eggs, nuts, grains, and nightshades can also trigger leaky gut. Dr. Wentz shares her tips on short-term elimination plans, tracking symptom responses, and safely reintroducing foods.
Nutrient deficiencies can prevent gut healing. Zinc and glutamine are two of the most critical nutrients for repairing the gut lining, yet they’re often depleted in people with autoimmune disease, chronic stress, or poor digestion. Discover how to assess your nutrient status and use targeted supplementation or food-based support to rebuild your gut barrier.
Gut infections and imbalances are hidden drivers. SIBO, Candida, mold colonization, and parasites like Blastocystis hominis all contribute to intestinal permeability. Discover how functional tests such as breath tests, organic acid testing, GI-MAP, or mycotoxin panels can uncover these hidden infections, and how to work with your practitioner to treat them effectively.
Healing your gut transforms overall health. Restoring gut integrity can lead to remission of Hashimoto’s and IBS, and even improve conditions like migraines, asthma, and allergies. Discover how strategies like mindful eating, stress reduction, and using key nutrients can help your intestinal lining thrive.
Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode!
Dr. Wentz’s new book, IBS: Finding and Treating the Root Cause of Irritable Bowel Syndrome, will be out on March 17, 2026. Many people with Hashimoto’s have irritable bowel syndrome, which can be both a root cause and symptom of autoimmunity. This comprehensive guide reveals how irritable bowel syndrome is often a catch-all diagnosis that overlooks treatable root causes. It offers a step-by-step approach to help readers understand what’s really driving gut symptoms, and how to create a personalized plan to restore gut health and overall wellness.
Order your copy of IBS: Finding and Treating the Root Cause of Irritable Bowel Syndrome here: https://thyroidpharmacist.com/ibs-book-preorders/
Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/
For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Oct 13, 2025 • 1h 2min
65: The Perimenopause Revolution With Dr. Mariza Snyder
In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz interviews Dr. Mariza Snyder, bestselling author and women’s health advocate, about one of the most misunderstood life transitions: perimenopause. Her new book, The Perimenopause Revolution, is a love letter to women navigating perimenopause. Together, they explore why this stage often feels like a second puberty, how declining hormones affect the entire body, and the steps women can take to feel like themselves again.
What you’ll learn in this episode:
Perimenopause is a neuroendocrine shift – a “second puberty.” Dr. Mariza explains how declining communication between the ovaries and brain leads to erratic hormones, destabilizing moods, and physical changes. Just like puberty and postpartum, this season reshapes our physiology and even rewires our brains.
Symptoms often begin earlier than expected. While the average age of menopause is around 52, many women feel perimenopause as early as their mid-to-late thirties, especially those with Hashimoto’s, PCOS, endometriosis, or high stress loads. Recognizing the signs early can help shorten the learning curve.
Progesterone declines first, and it impacts the brain. Early perimenopause is marked by low progesterone, leading to poor stress tolerance, sleep issues, mood swings, and PMS-like symptoms. Estrogen follows later with its own ripple effects, from hot flashes to joint pain and cognitive changes.
Why hormone replacement therapy (HRT) can be a game-changer. Despite fear-mongering, FDA-approved bioidentical hormones can be safe, affordable, and life-changing. Dr. Mariza shares her mother’s story, her own journey, and tips for advocating with doctors to get the support you need.
Lifestyle shifts are non-negotiable. From blood sugar balance and strength training to sleep hygiene and daily movement “snacks,” Dr. Mariza outlines the foundations that help women reclaim their energy and protect long-term health during this transition.
You’re not broken – you’re transforming. Perimenopause can feel like losing your old self. But with the right tools and support, it’s also an opportunity to rewrite your story and thrive in midlife and beyond.
Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode! Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/
For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Oct 6, 2025 • 1h 31min
64: Is Your Indoor Air Making You Sick? How to Fix it Fast With Mike Feldstein
In this episode of Thyroid Pharmacist Healing Conversations, Dr. Wentz interviews Mike Feldstein, founder of Jaspr, about the hidden health effects of indoor air and practical solutions you can use today.
Mike explains how modern building practices trap pollutants, why classrooms are a high-impact target for filtration, and the real difference between small retail purifiers and commercial air scrubbers. Tune in to learn about the best choices for indoor air filtering, and how this and other simple steps can relieve conditions like asthma and allergies, help you get a more restful sleep, and support recovery for anyone with autoimmune disease and chronic sensitivities.
What you’ll learn in this episode:
Why indoor air is often more polluted than outdoor air: Unlike outdoor environments where wind, sunlight, and rain naturally cleanse toxins, our homes trap mold, VOCs, and bacteria inside. As a result, indoor air can be 5 to 10 times dirtier than the air outside, driving brain fog, fatigue, allergies, and asthma. Targeted changes like daily ventilation, high-efficiency air scrubbers, and simple monitors can transform your environment into one that supports healing instead of undermining it.
How “sick building syndrome” affects your health: The energy-efficient buildings that started to be built in the 1970s seal in mold, chemicals, and poor ventilation. This hidden trade-off explains why so many people feel unwell in their own homes and workplaces.
Why size and scale matter in air purification: Small, store-bought purifiers often work like golf carts – fine for light use, but not built for real health demands. Air scrubbers operate more like SUVs, moving far more air through larger filters and reducing pollutants on a much bigger scale. Choosing the right “vehicle” for your space can mean the difference between slightly cleaner air and truly life-changing results.
Everyday toxins may be hiding in your home: Furniture, flooring, cleaning products, fragrances, and even diaper pails can release chemicals that linger in the air. These daily exposures add up, and clearing them can relieve symptoms you may not have connected to your environment.
Air scrubbers vs. basic purifiers: Store-bought purifiers may only improve air quality by 10 to 20%, while air scrubbers like Jaspr can reduce pollutants by up to 99%. That level of clean air can be life-changing for those with asthma, autoimmunity, or chronic sleep issues.
Clean air as a missing pillar of functional medicine: Just as water filtration and clean diets are now common practice, air quality deserves the same attention. Without it, even the best supplements and protocols may fall short of lasting results.
Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode! Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/
For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Sep 29, 2025 • 1h 11min
63: The Iodine Paradox: What Every Thyroid Patient Needs to Know – With Dr. Alan Christianson
In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz speaks with naturopathic endocrinologist and bestselling author Dr. Alan Christianson about the controversial role of iodine in thyroid health. While iodine is essential in small amounts, excess intake has been shown to trigger Hashimoto’s, worsen autoimmunity, and disrupt thyroid function.
Dr. Christianson shares how a carefully structured low iodine protocol has helped many of his patients reduce antibodies, normalize TSH, and in some cases, taper off thyroid medications. He also explores hidden dietary and lifestyle sources of iodine, why genetics play a role in tolerance, and how supporting nutrients like selenium and vitamin D can protect thyroid health.
What you’ll learn in this episode:
Why iodine is a double-edged sword for the thyroid. While essential in small amounts, iodine has one of the narrowest therapeutic ranges of any nutrient. Too much can trigger Hashimoto’s, worsen autoimmunity, and cause the thyroid to “shut down,” leading to hypothyroidism.
The genetic factor in iodine tolerance. Dr. Christianson explains how some people are adapted to coastal diets rich in iodine, while others with “inland genetics” are much more sensitive. These differences can explain why some people tolerate seaweed and kelp – while others see skyrocketing antibodies.
Hidden sources of iodine in your diet and home. Beyond seaweed snacks and iodized salt, high iodine exposure can come from dairy, processed bread, prenatal vitamins, and even personal care products like conditioner and lotion. Identifying these sources is a key step toward healing.
How a low-iodine reset can help the thyroid recover. Short-term iodine reduction (below ~100 mcg/day) can give the thyroid space to heal. Dr. Christianson shares research and patient stories showing that many people who stick with the reset see dramatic improvements, from normalizing thyroid labs to lowering antibodies, often within just a few months.
When to discuss med changes with your doctor. In some cases, a supervised low-iodine protocol may allow for gradual reductions in thyroid medication. Dr. Christianson notes that studies show many patients can safely lower – and some even stop – their meds, but emphasizes this process must be done cautiously, with close monitoring.
The co-nutrients that widen your “safety window.” Selenium, zinc, vitamin D, and iron aren’t optional extras; they’re critical for how your thyroid handles iodine. These nutrients support the enzymes that regulate iodine metabolism and help protect the thyroid from oxidative stress. When they’re low, excess iodine does more damage; when they’re optimized, your thyroid can tolerate a wider range without flaring. autoimmunity.
Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode! Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/
For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Sep 22, 2025 • 1h
62: Lung Detox Secrets for Healing Chronic Illness and Boosting Vitality With Christa Orecchio
In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz interviews longtime friend and collaborator Christa Orecchio, a clinical and holistic nutritionist with nearly two decades of experience in gut, adrenal, and lung health. They discuss a cutting-edge integrative approach to healing asthma, mold illness, long-COVID lung damage, and respiratory inflammation, with surprising connections to emotional trauma and nervous system regulation.
Christa shares how salicylates, environmental toxins, and even repressed grief can lead to persistent lung dysfunction, and how her new lung rejuvenation program combines herbal therapy, postbiotics, trauma healing, and targeted breathwork to reverse symptoms and restore cellular vitality.
Tune in to learn more about:
Why lung issues go beyond inflammation or allergies: Trauma, mold exposure, antibiotics, smoking or vaping, unresolved grief, and even early childhood infections can create deep dysfunction in the lungs. Addressing them is essential for lasting healing.
How environmental toxins silently damage lungs: Everyday exposures such as flame retardants, formaldehyde, pesticides, glyphosate, wildfire smoke, and nanoplastics can scar lung tissue over time. Detox support and air purification become essential, even for those living “clean.”
The surprising role of foods and oils in asthma: High-salicylate foods and products including dried fruits, apples, strawberries, plums, tomatoes, cucumbers, coffee, wine, and peppermint oil can trigger respiratory flares. Short elimination trials combined with salt therapy often bring quick relief.
The emotional-spiritual link to breathing: Unprocessed grief and trauma can lodge in the lungs, showing up as asthma, chronic cough, or shallow breathing. Healing through grief work, somatic therapies, or homeopathy can restore vitality and ease of breath.
Herbs and nutrients that rebuild the lungs: Lungwort, golden seal, lotus root, boswellia, DNA and RNA tissue factors, postbiotics, and mitochondrial supports such as CoQ10, PQQ, and L-carnitine help restore tissue integrity, reduce inflammation, and strengthen resilience.
Why nervous system healing is non-negotiable: Breathwork, EFT, and somatic trauma therapies shift the body out of fight-or-flight and into parasympathetic rest-and-heal mode. This nervous system reset unlocks true recovery for both lungs and thyroid.
Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode! Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/
For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Sep 19, 2025 • 1h 13min
61: Biology of Trauma: How Trauma Fuels Autoimmunity & Hashimoto’s – With Dr. Aimie Apigian
In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz interviews Dr. Aimie Apigian, physician and author of The Biology of Trauma. Together, they explore how unresolved trauma – often overlooked in thyroid care – can predispose the body to autoimmunity, create nervous system imbalances, and keep people stuck in chronic fatigue or thyroid symptoms despite “doing everything right.”
Dr. Apigian shares her journey from biochemistry and foster parenting to becoming a leading trauma expert, as well as her own experience with autoimmunity. She explains how trauma physiology differs from stress, why unresolved attachment wounds fuel thyroid issues, and what tools can help rewire the nervous system for safety and healing.
What you’ll learn in this episode:
Trauma isn’t always what you think. Many people dismiss their experiences because they didn’t have “big T” trauma. Dr. Aimie explains how even subtle or forgotten childhood events can rewire the nervous system, making the body feel unsafe and setting the stage for autoimmunity.
Autoimmunity can be a trauma response. The body’s immune system reflects what the nervous system has learned: “it’s not safe to be me.” This creates a biology of trauma that keeps us in fight, flight, or freeze, driving thyroid imbalances and chronic fatigue.
Why stress management isn’t enough. Breathwork, meditation, or cold plunges may help stress, but if the body is in trauma physiology, those tools can backfire. Healing requires working within your body’s capacity and building a “window of tolerance” for safety.
How attachment wounds can affect thyroid health. From not being held enough as a baby to learning to suppress needs in childhood, these early experiences train us to abandon ourselves. Dr. Aimie shares how these patterns directly connect to autoimmune conditions like Hashimoto’s.
Signs you might have stored trauma. Feeling constantly unsafe, being stuck in cycles of overwhelm, having unexplained fatigue, or always waiting for the “next shoe to drop” are all red flags that your body may be carrying unresolved trauma.
Tools that create a biology of safety. Somatic practices, EMDR, neurofeedback, and Dr. Aimie’s five somatic self-practices can shift the nervous system out of trauma and into safety – often in under five minutes – without needing to rely on substances or old coping strategies.
Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode! Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/
For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: https://thyroidpharmacist.com/articles/podcast/
Learn more about your ad choices. Visit megaphone.fm/adchoices

Sep 15, 2025 • 1h 12min
60: Reversing Hashimoto’s? The Unconventional Tools You Haven’t Tried Yet – With Lexi Yoo
In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz sits down with integrative nurse practitioner Lexi Yoo, founder of Yoo Direct Health, to explore unconventional, but highly effective, therapies for Hashimoto’s and other autoimmune conditions.
From low-dose naltrexone and hormone optimization to cutting-edge peptides, ozone therapy, and semaglutide (Ozempic), Lexi shares how she personalizes care to help patients finally see progress when standard treatments fall short.
They also dive into how to measure true healing using labs and symptom trackers, and why these innovative therapies should be accessible to everyday patients – not just biohackers.
Whether you’ve hit a plateau or are just starting your healing journey, this episode offers fresh, practical tools to help you move the needle on recovery.
Tune in to learn more:
Low-dose naltrexone (LDN) is a powerful, underused tool for modulating the immune system in Hashimoto’s. Lexi shares how she tailors dosing based on individual tolerance and symptoms, starting as low as 0.25 mg in sensitive cases. It can help improve mood, reduce inflammation and pain, regulate appetite, and support sleep – all of which are commonly disrupted in thyroid and autoimmune disorders.
Peptides like BPC-157, KPV, and Larazotide offer next-level support for gut healing and immune balance. These naturally-occurring compounds repair gut lining, reduce inflammatory triggers, and can be used strategically in gut protocols alongside supplements like glutamine and zinc carnosine. Lexi shares how using these together can accelerate healing in patients with Hashimoto’s, IBS, SIBO, and even post-surgical recovery.
Wellbutrin and semaglutide (Ozempic) aren’t just for depression or weight loss – they’re strategic tools for Hashimoto’s healing. Lexi explains how combining these medications with LDN can quiet food noise, stabilize dopamine and insulin signaling, and reduce inflammation that worsens autoimmune flares. These therapies can also support emotional resilience, especially in women juggling hormones, motherhood, careers, and chronic fatigue.
Testosterone replacement can be a game-changer for women with Hashimoto’s – and no, it won’t make you look like a bodybuilder. Lexi explains how testosterone supports the thymus gland, improves libido and energy, and can even reduce thyroid antibodies. She discusses various delivery methods including pellets, creams, and new oral options, emphasizing that personalized dosing and monitoring are key.
Ozone therapy is an emerging powerhouse for lowering thyroid antibodies and enhancing mitochondrial health. By delivering oxygen in a unique oxidative form, IV ozone helps improve blood flow, reduce inflammation, and support immune function – especially in patients with chronic infections, high TPO levels, or autoimmunity-related fatigue. Lexi also shares how she pairs ozone with UV light, rectal insufflation, and topical applications for targeted healing.
Semaglutide (Ozempic) can be a safe and strategic option for Hashimoto’s when used properly. Lexi clarifies the misunderstood connection between GLP-1 agonists and thyroid health, and how this medication – when supported by labs, nutrition, and exercise – can reduce systemic inflammation and support metabolic healing. She’s also seen benefits for PCOS, food addiction, joint pain, and even fertility in Hashimoto’s patients.
Be sure to subscribe to the Thyroid Pharmacist Healing Conversations podcast so you don’t miss an episode!
Sign up for the Thyroid Pharmacist Weekly Thyroid Solutions Newsletter here: https://thyroidpharmacist.com/gift/
Learn more about your ad choices. Visit megaphone.fm/adchoices


