CXOTalk

#ai #generativeai #drugdiscovery #pharma In this episode of CXOTalk, we have the pleasure of speaking with Dr. Alex Zhavoronkov, the founder and CEO of Insilico Medicine.Insilico Medicine uses artificial intelligence to enhance drug discovery. By combining generative adversarial networks (GANs), reinforcement learning, and other AI techniques, Insilico streamlines the design, synthesis, and testing of new molecules. Their approach has garnered attention, raising $400 million in funding so far.Dr. Zhavoronkov shares insights into Insilico's goals, such as the accelerated development and testing of small molecules targeting specific diseases. We also explore how their software impacts pharmaceutical R&D by enabling researchers to investigate new targets, design molecules with certain properties, and potentially predict the outcomes of clinical trials.Join us as we discuss the evolving landscape of pharmaceuticals and how generative AI can help discover new treatments for chronic diseases and promote a healthier future.The conversion covers these topics:► Early generative AI experiments & adversarial networks► Generative AI in molecular drug design► Advancements: AI techniques & reinforcement learning► Insilico Medicine's funding journey & challenges► Unique challenges in AI-based drug discovery► First validation of AI-generated molecules► Software for chemistry & biology applications► Traditional vs. Insilico Medicine's approach► Pharma challenges: high costs, low novelty, and diminishing returns► Potential billion-dollar payout for successful Phase II drugs► AI in drug development can increase success probability► Early partnerships with large pharma and lessons learned► Decision to stop doing pilots with big pharma companies► Generative AI and public data► De-biasing pharmaceutical research► Automating the workflow and quality control► Reinforcing generative AI with real experiments► “Drug discovery is brutal”► Drug discovery democratization► AI in medical writing► IP risks and generative AI► AI and robotics to prevent agingVisit our website for the audio podcast: https://www.cxotalk.com/episode/future-of-drug-discovery-generative-ai-in-pharma-and-medicineSubscribe to the newsletter: https://www.cxotalk.com/subscribeCheck out our upcoming live shows: https://www.cxotalk.comAlex Zhavoronkov, Ph.D. is the founder and CEO of Insilico Medicine, a leader in next-generation artificial intelligence technologies for drug discovery and biomarker development. He is also the founder of Deep Longevity, Inc, a spin-off of Insilico Medicine developing a broad range of artificial intelligence-based biomarkers of aging and longevity servicing healthcare providers and life insurance industry. In 2020, Deep Longevity was acquired by Endurance Longevity (HK: 0575). Beginning in 2015, he invented critical technologies in the field of generative adversarial networks (GANs) and reinforcement learning (RL) for the generation of novel molecular structures with the desired properties and generation of synthetic biological and patient data. He also pioneered applications of deep learning technologies for the prediction of human biological age using multiple data types, and transferred learning from aging into disease, target identification, and signaling pathway modeling. Under his leadership, Insilico has raised over $400 million in multiple rounds from expert investors, opened R&D centers in six countries or regions, and partnered with multiple pharmaceutical, biotechnology, and academic institutions, nominated 11 preclinical candidates, and has generated positive topline Phase 1 data in human clinical trials with an AI-discovered novel target and AI-designed novel molecule for idiopathic pulmonary fibrosis that received Orphan Drug...

#cybersecurity #aiCXOTalk host Michael Krigsman interviews Michal Pechoucek, CTO of Gen and AI researcher, on the impact of AI on cybersecurity.In this insightful discussion, the two participants explore the evolving relationship between AI and cybersecurity. The conversation covers a range of topics, from AI and machine learning (ML) tools in cyber defense and penetration testing to A/B testing in cyber attacks. The conversation also covers the challenges of AI and cybersecurity research and the maturity of AI-powered tools in the field. The conversation culminates in valuable advice for Chief Information Security Officers (CISOs) and Chief Information Officers (CIOs), as well as thoughts on the future of AI in cybersecurity, including the potential for cognitive attacks and the spread of misinformation.The conversation includes these topics:► Early applications of AI and deep learning in cybersecurity► Consumer cybersecurity and AI-enabled defenses► Evolving cybersecurity threats and cognitive attacks► AI and deep learning: Defending against automated attacks► Signature-based AI and deep learning to scale malware detection► The challenge of building AI for diverse cybersecurity threats► Importance of AI explainability in cybersecurity► AI-enabled cognitive attacks, identity theft, and the future of cybersecurity► AI to detect phishing attacks: Large language models and classification► Importance of AI in Cybersecurity for Boards of Directors► Bridging the gap between cybersecurity experts and boards► Personal data protection: Tips for better cybersecurity hygiene► Algorithm manipulation and privacy concerns; Algorithm manipulation and privacy► AI and ML tools in cyber defense and penetration testing► A/B testing in cyber attacks► AI recommendations on data collection► Challenges in AI and cybersecurity research► Advice for Chief Information Security Officers (CISO) and Chief Information Officers (CIO)► Future of AI in cybersecurity: cognitive attacks and misinformationJoin our community: https://www.cxotalk.com/subscribeRead the complete transcript: https://www.cxotalk.com/episode/ai-cybersecurity-cto-perspectiveMichal Pechoucek leads the core technology, innovation and R&D teams driving security engines as well as Gen's technology vision for human centered digital safety and beyond. He is also responsible for the company’s scientific research in the fields of Artificial Intelligence, machine learning, and cybersecurity. He previously served as CTO of Avast.Before joining Avast, Mr. Pechoucek spent over twenty years as a professor at the Czech Technical University (CTU) in Prague, during which he founded the Artificial Intelligence Center in 2001. Mr. Pechoucek has authored more than 400 high impact publications and contributed numerous innovative AI applications to research in computer science.While pursuing his academic career, Mr. Pechoucek co-founded several technology start-ups including cybersecurity firm Cognitive Security (acquired by CISCO in 2013), AgentFly Technologies, which specializes in controlling autonomous aircraft traffic, and Blindspot Solutions, which develops AI for industrial applications (acquired by Adastra Group in 2017). He directed the R&D Center for AI and Computer Security at CISCO Systems and worked as a strategist in the CISCO Security CTO office. He is also a venture partner with Evolution Equity Partners, a VC firm specialized in cybersecurity. Michal Pechoucek co-founded the prg.ai initiative aiming to transform Prague into a world-class AI super hub. He sits on the board of several AI startups and as an early investor supports Czech AI ecosystem.Michal graduated from University of Edinburgh and gained his PhD in Artificial Intelligence at CTU in Prague. He also worked as a visiting professor at the University of...

#nfl #dataanalytics The NFL's Chief Data and Analytics Officer explains how the National Football League uses data and analytics to gain a competitive edge on and off the field. Learn about the key metrics the league tracks, how the data informs player evaluations and team strategy, and how the NFL is using technology to enhance the fan experience. Our guest co-host for this episode is QuHarrison Terry, Head of Growth Marketing at Mark Cuban Companies.The conversation covers these topics:► NFL data goals: improve fan experience, league operations, and team performance► How the NFL uses data and analytics to personalize fan engagement and customer experience► Privacy and consent: addressing customer concerns in data usage► Governance and the democratization of data in the NFL► Four pillars of the NFL’s data and analytics strategy► Managing and leveraging data from the Super Bowl► How the NFL uses data to understand how fans consume content► The partner ecosystem for data and analytics technology in the NFL► Decision-making based on data vs. intuition► How the NFL manages change and disruption in the professional sports industry► How the NFL uses data and analytics to improve team performance► Generative AI and machine learning in the NFL► How the NFL organizes data at scale► Key data lessons: Repeatability, scalability, and governance► Collecting data from the Super Bowl halftime show► Future of data, analytics, and converged content in the NFLSubscribe for more live episodes: https://www.cxotalk.com/subscribeRead the full transcript and watch related episodes: https://www.cxotalk.com/episode/data-wins-inside-nfls-analytics-strategyPaul Ballew currently serves as the National Football League’s Chief Data & Analytics Officer. Based in New York, Paul directs the League’s extensive data and analytics operations across the Game, Fans and Engagement. This mission is centered on ensuring that the NFL’s data assets and advanced analytic capabilities are leveraged to improve on-field football, overall fan experience and commercial outcomes for the League, clubs and partners. In advancing the Game, Paul and team support Football Operations’ critical workstreams and Player Health & Safety’s major initiatives, where the power of analytics is critically important to the future of the game. Paul and team are also leading the key initiatives on deepening fan engagement through enhanced fan modeling, predictive analytics, and the personalization of content and experiences.Throughout his career Paul has built and led transformational data and analytic organizations across leading companies and industries. Previously he served as Chief Data and Analytics Officer for the Loblaw LTD the largest retailer, pharmaceutical provider and real estate investment trust in Canada. He was responsible for establishing the company’s data and analytics functions, data management operations, data science activities, and the Artificial Intelligence and Machine Learning Center of Excellence. Prior to Loblaw, Paul’s decades of experience in the field includes leading the formation of the data and analytics organizations at Ford Motor Company, Nationwide Financial, Dun and Bradstreet and General Motors. Paul’s experience in the data and analytics field is centered on turning insights into action through close collaboration with business partners with the goal of improving customer relationships and driving operational excellence.QuHarrison Terry is Head of Growth Marketing at Mark Cuban Companies, a Dallas, Texas venture capital firm, where he advises and assists portfolio companies with their marketing strategies and objectives.Previously, he led marketing at Redox, focusing on lead acquisition, new user experience, events, and content marketing. QuHarrison has been featured on CNN, Harvard Business Review,...

#ai #chatgpt #generativeai In this episode of CXOTalk, the Chief Technology Officer of EY, who is Nicola Marini Bianzino, explains why generative AI is an arms race. We explore the defining characteristics of ChatGPT and similar tools, and the ethical and legal responsibilities of generative AI. Discover how generative AI will impact the future of work in the enterprise and the importance of ethical AI guidelines for technology developers.The conversation includes these topics:► Generative AI is an arms race► Impact of generative AI on the enterprise► Defining characteristics of ChatGPT► Ethical and legal responsibilities of generative AI► AI governance in the enterprise► What jobs may generative AI make redundant?► What is the impact of generative AI on knowledge management?► How will generative AI change the future of work in the enterprise?► Legal implications of generative AI► “Why do tools such as Google Bard or ChatGPT hallucinate?”► Challenges to enterprise adoption of AI tools► Advice to business leaders on adopting AI in the enterprise► Importance of ethical AI guidelines for technology developers in the enterprise► Comparison of ChatGPT to low code, no code software toolsNicola Morini Bianzino is EY's Global Chief Technology Officer, focused on bringing technology products to EY clients and positioning technology at the heart of the organization. With a 20-year track record of driving technology strategy innovation, he advises global clients on technology investment and their innovation agendas, providing industrialized technology products to meet their most pressing business needs.An early AI pioneer, he wrote a thesis on the application of neural networks to business in 1997. Nicola is a high-profile global media commentator and contributes to MIT Sloan Management Review, Forbes and HBR. A thought leader on AI, machine learning, innovation and big data, he is passionate about extracting value from technology investment. He holds a master’s degree in Artificial Intelligence and Economics from the University of Florence.

Join us as we explore AI project failures with guests Iavor Bojinov, Assistant Professor at Harvard Business School, and QuHarrison Terry, Head of Growth Marketing at Mark Cuban Companies. They discuss the causes of AI failures, differences from traditional technology projects, and offer practical advice on how to avoid failures. They also touch on ethical and privacy considerations. A must-watch for business leaders building AI groups.

On CXOTalk episode 777, we speak with Kurt John, the Chief Security Officer of Expedia Group, who discussed managing and leading cybersecurity in 2023. From building a decision support structure to explaining the value of security to boards of directors, this interview takes a deep dive into the life of a modern Chief Security Officer.We are joined by guest co-host, QuHarrison Terry, the Chief Growth Officer at Mark Cuban Companies.Don't miss this opportunity to gain valuable insights into the future of cybersecurity and hear from a seasoned leader in the field.Here are the topics covered in this discussion:On Expedia Group and Kurt John's roleOn complexity in the security landscapeOn technical threats to considerOn security for travelers, partners, and employeesOn security in the Expedia Group brands and ecosystemOn building a decision support structure for securityOn defining boundaries of the security ecosystemOn security and privacy as market differentiatorsOn threat intelligence and business outcomesOn preventing fraud in e-commerce with the security value chainOn information sharing to prevent fraudOn explaining the value of security to boards of directorsOn investments in security and cost savingsOn companies adopting GDPR as a standardOn the imperfect nature of security systemsOn the importance of security post-mortemsOn advice for new CISOsOn the role of AI in securityOn the impact of security and trust in the travel industryKurt John is Global Chief Security Officer at the Expedia Group, where he overseas governance and execution of cybersecurity, physical security and privacy. He is also a non-resident senior fellow at the Atlantic Council where he helps to think through the most relevant Cybersecurity challenges at the intersection of geopolitics, business and security facing the United States and its allies. This includes making recommendations for policy makers to help bolster the security of our way of life. Kurt holds multiple board positions in private and public organizations including Virginia Innovation Partnership Authority – the Commonwealth’s initiative to drive innovation of the tech economy.QuHarrison Terry is a growth marketer at Mark Cuban Companies, a Dallas, Texas venture capital firm, where he advises and assists portfolio companies with their marketing strategies and objectives. Previously, he led marketing at Redox, focusing on lead acquisition, new user experience, events, and content marketing. QuHarrison has been featured on CNN, Harvard Business Review, WIRED, Forbes and is the co-host of CNBC’s Primetime Series – No Retreat: Business Bootcamp. As a speaker and moderator QuHarrison has presented at CES, TEDx, Techsylvania in Romania, Persol Holdings in Tokyo, SXSW in Austin, TX, and more. QuHarrison is a 4x recipient of Linkedin’s top voices in Technology award.

#cybersecurity #ciso #ai #aisecurityIn this exclusive interview, NVIDIA's Chief Security Officer, David Reber, discusses the complexity of the company's product line and its impact on security. He explains why NVIDIA’s complex hardware and software product line demands a diverse portfolio of security solutions. Reber highlights the role of AI and machine learning in security and data protection, and explains how AI changes cybersecurity.Reber presents an ecosystem view of security, where knowledge and trust play a crucial role in protecting against breaches.The conversation also sheds light on the interlinked relationship between data protection and protecting against breaches, the importance of monitoring the data supply chain, and customer experience in security. Reber concludes by stressing the importance of innovation and how security teams should focus on enabling innovation instead of stopping it.The conversation includes these topics:► How does NVIDIA's product line make security complex?► How does NVIDIA manage security risk?► What is the impact of AI and machine learning on security and data protection?► What is NVIDIA’s security ecosystem and why is it important?► Why are technology, education and training all essential to maintain cybersecurity?► How does AI make security a data problem?► “How do you protect distributed data sets?”► “It's AI until you trust it. Then it's automation.”► How do you balance security and protection against employee productivity?► What does customer experience mean in security?► What is the role of AI governance in security programs?► How does NVIDIA integrate security into product development?► How do we handle negative consequences of autonomous algorithmic systems?► Why do security breaches happen so often?► Advice to business leaders on AI and security?Subscribe for more: https://www.cxotalk.com/subscribeSee related conversations and transcripts: https://www.cxotalk.com/episode/cybersecurity-strategy-2023David Reber serves as the chief security officer and head of product security at NVIDIA. Before NVIDIA, Reber served over a decade as a senior staff officer in the US Intelligence Community. He held the position of senior director of security for Nutanix Frame and Government Cloud Services. His background spans enterprise secure cloud service architecture, advanced cyber operations, offensive security research, global enterprise security, secure mobile tactical communications and insider threat. Reber holds a bachelor’s degree in Information Sciences and Technology from the Pennsylvania State University.

As a CIO, understanding the cloud ecosystem is essential for leveraging cloud computing for digital transformation, agility, and innovation.To understand why the ecosystem is so important for any move to the cloud, we spoke with the head of Strategic Ecosystem & Industry Solutions at VMware, Zia Yusuf.During the conversation, Zia explains the cloud ecosystem, why it's a challenging issue for many CIOs, and offers advice for migration planning and investing in the cloud.The discussion covers these topics:► What is the cloud ecosystem?► How does the cloud ecosystem drive customer success?► What are the roles and responsibilities of cloud ecosystem participants?► How is customer success different in the cloud from on-premises?► What are the business impacts of multicloud and hybrid cloud solutions?► How important is the ecosystem to cloud migration?► What is the role of ecosystem in innovation and cloud adoption?► Advice to CIOs on migration from on-premises to cloud?► How should CIOs plan and architect their cloud computing ecosystem?► What are the best metrics to use for evaluating a cloud migration strategy?Read the complete transcript: https://www.cxotalk.com/episode/cloud-ecosystem-guide-ciosZia Yusuf joined VMware in 2021 as VMware’s Senior Vice President of Strategic Ecosystem and Industry Solutions, responsible for building joint horizontal and industry-centric solutions with our ecosystem and alliances across Dell, global cloud providers (hyperscalers), global system integrators, and global ISVs.Prior to VMware, Zia was a Senior Partner & Managing Director at Boston Consulting Group (BCG)—serving as a core member of the firm’s Technology Advantage, and Technology, Media & Telecommunications practices. Before BCG, Zia was CEO of a leading IoT startup called Streetline, and an executive vice president at SAP where he served as head of the global ecosystem and partner group. Zia holds a Bachelor of Arts from Macalester College, a Master of Science in International Affairs from the School of Foreign Service at Georgetown University and an MBA from Harvard Business School.

#creatoreconomy #aitools Artificial intelligence is rapidly changing the way creators and entrepreneurs build and monetize their businesses. From content creation to e-commerce, AI tools are making it easier and faster for creators to produce high-quality content and build a following.Our guest is AI expert Riley Brown, who has quickly established himself as a leading voice in the creator economy. Riley has used his deep understanding of AI tools to grow his TikTok channel at an unprecedented rate. Riley will share his expertise on the latest developments and best practices for using AI tools to create text, audio, and video.The conversation includes these topics:► Rise in popularity of AI tools for content creation► AI tools improve digital communications► The creator economy and its impact on social media► Differences between AI tools and traditional creator tools► AI-powered content creation is the future of empowering creators► AI tools can help employees create their own personal brand► Employer objections to employees building strong personal brands► Creating AI-generated avatars for storytelling using various tools► How to use ChatGPT for best results► TikTok AI influencer describes future plansRead the complete transcript: https://www.cxotalk.com/episode/ai-tools-creator-economySubscribe to the CXOTalk newsletter: https://www.cxotalk.com/subscribe

#cio #digitaltransformation Technology investment strategy and innovation planning are particularly challenging during this period of economic change.In this interview, the Global CIO and CTO of the Solutions & Services Group of Lenovo, Arthur Hu, shares strategies for successful technology investment planning in 2023.He will discuss how he aligns technology investments with business goals, evaluates potential investments, and navigates the ever-changing business landscape. As a CIO and CTO, he has a unique perspective on the role of technology in driving growth and innovation. With his guidance, you'll gain valuable insights and strategies for your own technology investment planning in the coming year.The conversation covers these topics:-- Navigating uncertainty: CIO investment strategy for 2023-- What are the criteria for technology investment decisions in 2023?-- Include technology adoption and change management in investment planning-- Technology debt has a negative impact on business agility-- How to plan technology budgets during times of economic uncertainty-- How does Lenovo align business and technology investments?-- How can CIOs create a culture of business growth?-- The new CIO mindset of growth and business value-- Data sovereignty, privacy, and international compliance-- How to balance short-term results with long-term technology investments?-- Metrics and KPIs for measuring technology investment planning-- The best CIOs innovate to create value-- CIO and CTO investment planning compared-- Advice for CIOs: “Be the person of yes”Subscribe to CXOTalk: https://www.cxotalk.com/subscribeRead the full transcript: https://www.cxotalk.com/episode/cio-cto-investment-strategy-2023Arthur Hu is Senior Vice President and Chief Information Officer for Lenovo as well as the Chief Technology Officer of the Solutions & Services Group (SSG).As Lenovo’s Global CIO, Mr. Hu leads the enterprise-wide IT organization that is driving the technology-enabled transformation of Lenovo. Under his direction, Lenovo’s IT team has emerged as a strategic partner to the business groups, focusing on innovation, business value, and customer experience.Earlier this year, Mr. Hu was appointed to the additional position of Chief Technology Officer for the Solutions and Services Group (SSG). In this role, he leads the Research and Development organization within SSG, responsible for developing innovative solutions to bring to customers worldwide.Since joining Lenovo in 2009, Mr. Hu has held several executive and operational leadership roles in the company and is a member of the Lenovo Executive Committee.