
Mastering Nutrition
Welcome to the Mastering Nutrition podcast.
Mastering Nutrition is hosted by Chris Masterjohn, a nutrition scientist focused on optimizing mitochondrial health, and founder of BioOptHealth, a program that uses whole genome sequencing, a comprehensive suite of biochemical data, cutting-edge research and deep scientific insights to optimize each person's metabolism by finding their own unique unlocks.
He received his PhD in Nutritional Sciences from University of Connecticut at Storrs in 2012, served as a postdoctoral research associate in the Comparative Biosciences department of the University of Illinois at Urbana-Champaign's College of Veterinary Medicine from 2012-2014, served as Assistant Professor of Health and Nutrition Sciences at Brooklyn College from 2014-2017, and now works independently in science research and education.
Latest episodes

Dec 28, 2017 • 3min
Glycine With a Meal for Blood Sugar | Chris Masterjohn Lite #37
Got blood sugar problems? Glycine might help! 3-5 grams of glycine before a meal helps stabilize your blood sugar after the meal, and 15 grams a day every day helps improve long-term blood sugar stability in type 2 diabetes. Listen to this podcast for the best way to implement this strategy. To get these episodes free of ads, with transcripts, and weeks or sometimes even months before they are released to the public, along with access to monthly live Q&A sessions, sign up for the CMJ Masterpass at https://chrismasterjohnphd.com/masterpass. Use the code LITE10 to get 10% off. To make it easier to get the discount, use this link, which has the coupon already activated: https://masterpass.chrismasterjohnphd.com/cmj-masterpass/2200/buy?coupon=LITE10 Access the show notes, transcript, and comments here.

Dec 26, 2017 • 4min
Collagen Before Your Workout for Tendon Health | Chris Masterjohn Lite #36
Achy joints? Tendon pain? Just looking to stay youthful forever? Taking 15 grams of collagen before your workout, maybe with a little vitamin C, can do wonders for your tendon health. Your tendons aren’t that metabolically active and they don’t vacuum up what they need as actively as your muscles do. Getting the collagen peptides into your bloodstream before your workout makes them available to your tendons when your workout starts pumping blood directly into all the nooks and crannies where those shy little tendons are found. Here is the link to the Sigma Nutrition episode with Danny Lennon and Keith Baar: https://sigmanutrition.com/episode143/ To get these episodes free of ads, with transcripts, and weeks or sometimes even months before they are released to the public, along with access to monthly live Q&A sessions, sign up for the CMJ Masterpass at https://chrismasterjohnphd.com/masterpass. Use the code LITE10 to get 10% off. To make it easier to get the discount, use this link, which has the coupon already activated: https://masterpass.chrismasterjohnphd.com/cmj-masterpass/2200/buy?coupon=LITE10 Access the show notes, transcript, and comments here.

Dec 21, 2017 • 1h 33min
Creatine: Far More Than a Performance Enhancer | Mastering Nutrition #48
Creatine has diverse roles in the body, including muscle development, cognitive performance, mental health, and gastrointestinal health. It plays a key role in energy metabolism during exercise by aiding ATP synthesis and regulating acidity. Creatine supplementation can help with methylation problems and does not cause hair loss. Safety concerns related to kidney health are discussed. Paleo Valley offers delicious grass-fed beef sticks and organ complex with a limited-time discount for podcast listeners.

Dec 13, 2017 • 4min
Get Better Sleep With Glycine | Chris Masterjohn Lite #35
Do you have trouble sleeping, or wish you felt more rested and energized during the day? Glycine might be one of the best things you can try. It doesn’t just have a calming effect, but it improves sleep quality and can make you feel more rested even on the same amount of sleep. In this episode, I discuss how to use glycine for better sleep and why you should consider both free glycine and hydrolyzed collagen. To get these episodes free of ads, with transcripts, and weeks or sometimes even months before they are released to the public, along with access to monthly live Q&A sessions, sign up for the CMJ Masterpass at https://chrismasterjohnphd.com/masterpass. Use the code LITE10 to get 10% off. To make it easier to get the discount, use this link, which has the coupon already activated: https://masterpass.chrismasterjohnphd.com/cmj-masterpass/2200/buy?coupon=LITE10 Access the show notes, transcript, and comments here.

4 snips
Dec 11, 2017 • 8min
This is the Bloodwork You Should Get for MTHFR | Chris Masterjohn Lite #34
Chris Masterjohn, a nutritional scientist and MTHFR expert, discusses the essential bloodwork to evaluate the effectiveness of MTHFR treatment. Topics include interpreting glycine and sarcosine levels, differentiating between serum and plasma folate, and optimizing MTHFR function through methyl folate conservation and glycine assessment.

6 snips
Dec 6, 2017 • 9min
What to Do About MTHFR | Chris Masterjohn Lite #33
Got MTHFR? I got you: here’s what you can do with nutrition to optimize for your genetics. MTHFR mutations increase your need for choline and glycine. It’s key to get methylfolate in your diet, but high-dose methylfolate supplements are not the solution. You need to boost choline as an alternative supply of methyl groups, and creatine supplementation can help you better conserve your methylfolate by reducing the need to use it. This is important because adequate methylfolate preserves glycine and prevents it from being lost. Too little protein hurts methylation, but too much worsens the loss of glycine, so you need to hit the Goldilocks amount. Finally, you need to get more glycine to make up for whatever you’re losing. In this episode, I explain how to use food and supplements to make all this work in your favor. To get these episodes free of ads, with transcripts, and weeks or sometimes even months before they are released to the public, along with access to monthly live Q&A sessions, sign up for the CMJ Masterpass at https://chrismasterjohnphd.com/masterpass. Use the code LITE10 to get 10% off. To make it easier to get the discount, use this link, which has the coupon already activated: https://masterpass.chrismasterjohnphd.com/cmj-masterpass/2200/buy?coupon=LITE10 Access the show notes, transcript, and comments here.

Dec 4, 2017 • 9min
How to Know If You Need to Care About Your MTHFR | Chris Masterjohn Lite #32
Should you care about your MTHFR? Here’s how to find out your MTHFR genetic status and know how it affects you. MTHFR is an enzyme that allows folate, or vitamin B9, to support a process known as methylation. Methylation is important to mental health, cardiovascular health, sports performance, and preventing cancer, just to name a few. In this episode, I show you how to find your MTHFR genetic status. I also discuss how the various different genetic combinations impact you and how you can leverage that information to determine how strictly you should follow the dietary recommendations I’ll outline in the next episode. To order a StrateGene report while kicking a small commission my way at no extra cost to you, use this link: chrismasterjohnphd.com/strategene I appreciate the support! The audio of this episode was generously enhanced and post-processed by Bob Davodian of Taurean mixing. You can find more of his work at taureanonlinemixing.com. To get these episodes free of ads, with transcripts, and weeks or sometimes even months before they are released to the public, along with access to monthly live Q&A sessions, sign up for the CMJ Masterpass at https://chrismasterjohnphd.com/masterpass. Use the code LITE10 to get 10% off. To make it easier to get the discount, use this link, which has the coupon already activated: https://masterpass.chrismasterjohnphd.com/cmj-masterpass/2200/buy?coupon=LITE10 Access the show notes, transcript, and comments here.

Nov 4, 2017 • 5min
Are You Coming to Wise Traditions?
Are you coming to Wise Traditions 2017? It's in Minneapolis, with some pregame events beginning on Thursday November 9th and the main conference running from Friday, November 10th through Monday, November 13th. I'm excited to see friends like Ben Greenfield and Laura Schoenfeld, to meet many other people I know only through the internet, and to spend some face-to-face time with lots of people who share traditional diets as a common interest. I'll be giving two talks, plus teaching an all-day interactive course on measuring and managing nutritional status. Here's what I'm doing: On Saturday, I'll be giving a talk on the role of protein, fat, carbohydrate, vitamins, and minerals in achieving an optimal hormonal balance. On Sunday, I'll be giving a talk "Methylate Your Way to Mental Health: Beyond Folate and B12 Supplements." On Monday, I'll be teaching an all-day interactive course called "Measuring and Managing Nutritional Status Masterclass." To register for the conference, go here. Please note that the Monday class on managing nutritional status comes separately. When you sign up, look for the "Monday Event Registration" header on the form, and change the dropdown menu from "No Monday Event Selected" to "Chris Masterjohn (includes lunch)." The Masterclass will take each of the essential nutrients, and cover both the "what" and the "why" behind the signs and symptoms of deficiency, the distribution in the diet, and the lab work used to assess nutritional status. It will consist of 10-15 minute chunks of lecture interspersed with questions that I'll give you. You'll vote on the answers with an app on your mobile device or laptop and we'll look at how people respond (anonymously in aggregate), often using the responses as a basis for discussion. You will have numerous opportunities to ask me questions about what we cover through the class and a more free-for-all-style opportunity to ask me anything at the end. Sound great? Register here! Register for Wise Traditions, 2017 Hope to see you there, Chris

Oct 10, 2017 • 10min
How We Make Ketones | MWM Energy Metabolism Cliff Notes #32
Exploring the process of ketogenesis and its relationship with the depletion of oxaloacetate. Difference between biochemical and physiological effects on ketogenesis. Process of ketogenesis and production of beta-hydroxybutyrate. Differences between acetoacetate and beta-hydroxybutyrate and the role of ketone breath.

Oct 9, 2017 • 10min
Cortisol and Gluconeogenesis |MWM Energy Metabolism Cliff Notes #31
This podcast explores how cortisol regulates gluconeogenesis and increases glucose availability to the brain. It discusses the relationship between cortisol, gluconeogenesis, and carbohydrate restriction, and examines the potential connection between high-fat, low-carbohydrate diets and cortisol levels.