Sebastian Mallaby is a journalist and author. His latest book, The Power Law, is an exploration of the history and impact of venture capital that seeks to explain how VCs see the world and why it matters. In this conversation, we discuss why VC is so different from any other asset class, why VC networks should be considered a third core institution of capitalism alongside firms and markets, and whether VC has a positive impact in the world. You can order the Power Law here. ----------------- Thanks to Cofruition for consulting on and producing the show. You can learn more about Entrepreneur First at www.joinef.com and subscribe to my weekly newsletter at tib.matthewclifford.com

Allister Furey is co-founder and CEO of Sylvera, a technology startup building a ratings agency for carbon markets. In this conversation, we discuss why evaluation and verification is so important for building a net-zero economy and the challenges that face innovators and investors in today's market. We talk through how Sylvera creates ratings for carbon projects and why this might be the key to unlocking trillions of dollars of investment for carbon offset and removal initiatives (Allister used to work at Entrepreneur First and I am a small investor in Sylvera). ----------------- Thanks to Cofruition for consulting on and producing the show. You can learn more about Entrepreneur First at www.joinef.com and subscribe to my weekly newsletter at tib.matthewclifford.com

Rohit Krishna is a venture capitalist and the writer behind Strange Loop Canon, one of my favourite Substacks (and one that regular readers of the TiB newsletter may recognise). In this wide-ranging conversation, we talk about how billionaires can be better at philanthropy, why identifying extreme talent is so challenging, new ways to invest in talent, why cities tend to last so much longer than companies, and much more. ----------------- Thanks to Cofruition for consulting on and producing the show. You can learn more about Entrepreneur First at www.joinef.com and subscribe to my weekly newsletter at tib.matthewclifford.com

Michelle You is co-founder and CEO of Supercritical, a startup that helps companies achieve Net Zero through carbon removal. Michelle is a serial entrepreneur (she was previously one of the founders of Songkick) and in this conversation, we dive into why she decided to focus on carbon removal for her next company. We also explore why the label Net Zero can be misleading, the challenges of creating new markets in carbon, and which carbon removal technologies she’s most excited about. ----------------- Thanks to Cofruition for consulting on and producing the show. You can learn more about Entrepreneur First at www.joinef.com and subscribe to my weekly newsletter at tib.matthewclifford.com

Christian Hernandez is one of the founding partners of 2150, a venture capital firm dedicated to backing startups that are reinventing how cities are built, run, and maintained - with a particular focus on sustainability and reducing carbon emissions. In this conversation, we talk about the role that venture capital and startups have to play in addressing the climate crisis. We discuss the most promising areas where startups can make a difference, why climate change is a national security issue, and much more. Enjoy this conversation with Christian Hernandez In the discussion, Christian recommends several books including: All Hell Breaking Loose, Uninhabitable Earth, and How to Avoid a Climate Disaster. You can read Christian’s blog posts here. ----------------- Thanks to Cofruition for consulting on and producing the show. You can learn more about Entrepreneur First at www.joinef.com and subscribe to my weekly newsletter at tib.matthewclifford.com

Tony Kulesa is one of the founders of Petri, a new approach for funding formation stage startups at the intersection of biology and engineering. We spend a lot of this conversation talking about why there is such an explosion of activity in biotech entrepreneurship today and why new models for supporting and financing founders are needed. Regular readers of the Thoughts in Between newsletter may also remember that we recently discussed Tony’s excellent essay on Tyler Cowen’ and talent curation. We jump into this topic towards the end of this episode. ----------------- Thanks to Cofruition for consulting on and producing the show. You can learn more about Entrepreneur First at www.joinef.com and subscribe to my weekly newsletter at tib.matthewclifford.com

Jason Crawford is the founder of Roots of Progress, a nonprofit dedicated to establishing a new philosophy of progress for the 21st century. Jason is a prolific writer on the history of science and technology and is one of the leading figures in the Progress Studies community. In this conversation, we discuss what causes progress; why it's not universally popular; what the history of bicycle tells us about why advances in technology sometimes take so long; why the future people imagined in the 1960s didn't happen; and much more. ----------------- Thanks to Cofruition for consulting on and producing the show. You can learn more about Entrepreneur First at www.joinef.com and subscribe to my weekly newsletter at tib.matthewclifford.com

Azeem Azhar is an entrepreneur, investor, and the creator of Exponential View - a newsletter and community dedicated to understanding the future. He's the author of the new book, Exponential, which explores how accelerating technology is changing our world faster than our institutions are designed to react. In this conversation, we discuss some of the big ideas in the book, from the emergence of superstar corporations to the future of work and cities. I highly recommend the book, which I think is the best guide so far to navigating the social and political challenges of the internet age. ----------------- Thanks to Cofruition for consulting on and producing the show. You can learn more about Entrepreneur First at www.joinef.com and subscribe to my weekly newsletter at tib.matthewclifford.com

Ilan is CEO of Activate, a non-profit fellowship that enables entrepreneurial scientists to transform their research into world-changing deep tech products and businesses. There are lots of parallels between my day job at Entrepreneur First and what Ilan is building at Activate, so it was great to explorie what we’ve both learned in this conversation. Unlike EF, Activate is focused on science that is going to take a long time, often at least a couple of years, before it’s ready for even the earliest stage venture capital. I think this is a really important space and there are big lessons for how we stimulate breakthrough innovation. ----------------- Thanks to Cofruition for consulting on and producing the show. You can learn more about Entrepreneur First at www.joinef.com and subscribe to my weekly newsletter at tib.matthewclifford.com

My guests today are Jess Whittlestone and Jack Clark. Jess is a senior research associate at the University of Cambridge’s Centre for Existential Risk. Jack is a co-founder of Anthropic, an AI safety and research company, and was previously Policy Director at OpenAI. Together they are co-authors on a new paper on why and how governments should monitor AI deployment, which you can read here. In this conversation, we discuss the paper and the ways in which governments need to act not to ensure AI is a force for good in their societies. Thanks to Cofruition for consulting on and producing the show. You can learn more about Entrepreneur First at www.joinef.com and subscribe to my weekly newsletter at tib.matthewclifford.com