Dr. Tomas Neilan discusses cardiotoxicity of novel immunotherapies, focusing on immune checkpoint inhibitors and their adverse cardiac effects. Topics include diagnosis, treatment, and challenges of ICI-related myocarditis, emphasizing the importance of baseline assessments and prompt recognition. The episode also touches on subclinical myocarditis, management strategies, and the impact of corticosteroids on cancer outcomes.

CardioNerds discuss a complex case involving a 72-year-old man with various symptoms and a history of different medical conditions. The patient is diagnosed with drug-induced lupus due to hydralazine after undergoing a thorough work-up. Expert commentary is provided on the challenges of diagnosing and treating drug-induced lupus. The podcast delves into the complexities of differential diagnosis, treatment strategies, and the importance of considering malignancy in such cases.

CardioNerds discuss GLP-1 receptor agonists in heart disease patients, exploring benefits, guidelines, and trial data. Dr. McGuire explains ease of use and efficacy, emphasizing patient support. They also cover samagletide therapy initiation, dosage levels, and combination therapy with SGLT2 inhibitors for heart failure and diabetes management. Future interventions for obesity and cardiovascular safety are highlighted.

Explore the role of palliative care in heart failure beyond end stages, challenging misconceptions. Learn about integrating palliative care into management for improved quality of life. Reflect on the importance of compassionate patient support in cardiology, emphasizing empathy over medical interventions.

Cardiologists discuss a challenging case of bacterial myocarditis in a young woman with history of drug use. Detailed analysis of differential diagnosis, cardiac involvement, and management of cardiogenic shock. Emphasis on avoiding cognitive bias and multidisciplinary approaches in diagnosis.

Discussing the importance of managing obesity to prevent cardiovascular disease, the podcast covers lifestyle recommendations, pharmacologic treatment options, and future therapies. Topics include tailored counseling, policy efforts to address obesity as a public health concern, advances in weight loss medications such as semaglutide, and the intersection of obesity medicine and heart failure.

Topics discussed include diagnosing and classifying heart failure, the diagnostic process for rapidly progressive heart failure in a younger patient, physical exam findings and classification of a heart failure patient, analysis of initial laboratory results and patient triage, evaluation and monitoring, treatment options for rapidly progressive heart failure, and imaging surveillance challenges for cardiac sarcoidosis.

Dr. Javed Butler, an advanced heart failure and transplant cardiologist, discusses the 2022 AHA/ACC/HFSA guideline for the management of heart failure. Topics include the management of cardiogenic shock, the use of intra-aortic balloon pump, and personalized care for patients with cardiogenic shock.

Dr. Juan Lopez-Mattei, an expert in cardio-oncology and director of cardiac imaging, discusses cardiac tumors, differentiating between primary and secondary tumors. They explore symptoms, diagnostic methods, and treatment options. They highlight the importance of imaging modalities and the necessity of tissue diagnosis for primary tumors. The speakers express their appreciation for cardio-oncology and emphasize the importance of collaboration in patient care.

Dr. José Joglar and Dr. Mina Chung discuss the key takeaways from the 2023 ACC/AHA/ACCP/HRS Atrial Fibrillation Guidelines, including the updated staging scheme, the effects of alcohol and caffeine on AF, improving stroke prevention, the evolving importance of rhythm control, shared decision-making, and the process of developing clinical guideline documents.