Febrile

In our Season 4 finale wrapping up 2024, Febrile is excited to host our biggest guest list yet to discuss the importance of International Medical Graduates (IMGs) in infectious diseases! Our guests:Ana Del Valle (Pediatric ID faculty at Arkansas Children’s Hospital)Cristina Tomatis (Pediatric ID faculty at Nationwide Children’s Hospital)Diego Cruz (Current pediatric resident and recent graduate of pediatric ID fellowship program at Nationwide Children’s Hospital)Radhika Sheth (Adult ID faculty at Henry Ford Health System)Shweta Anjan (Adult ID faculty at University of Miami and Jackson Memorial Hospital)Zheyi Teoh (Pediatric ID faculty at Seattle Children’s Hospital)Cesar Berto (Adult ID faculty at University of Alabama Birmingham)Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.comFebrile is produced with support from the Infectious Diseases Society of America (IDSA)

Drs. Jonathan Ryder and Sarah Turbett discuss blood culture stewardship!Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.comFebrile is produced with support from the Infectious Diseases Society of America (IDSA)

Join Daniel Karlin, an antimicrobial expert from UCLA, Christine Pham, a seasoned professional in antimicrobial applications, and Daisuke Furukawa, a Stanford researcher specializing in antibacterial studies, as they navigate the complexities of antimicrobial use at the end of life. They delve into ethical dilemmas, emphasizing the need for clear communication and palliative care integration. The trio also reflects on emotional challenges faced by healthcare providers and families, advocating for better collaboration and understanding in managing infections during terminal care.

In this discussion, Hussam Tabaja, Supavit "Mac" Chesdachai, and Daniel DeSimone from Mayo Clinic explore the intricate world of vascular graft infections. They emphasize the importance of multidisciplinary teamwork in preventing and managing these infections. The conversation touches on the challenges in diagnosis and preoperative evaluations, illustrated through compelling patient case studies. They also address health disparities and advocate for a collaborative approach to treatment, highlighting the critical role of social determinants in accessing care.

This StAR episode features the CID State-of-the-Art Review on Unintended Consequences: Risk of Opportunistic Infections Associated with Long-term Glucocorticoid Therapies in Adults.Our guest stars this episode are:Daniel Chastain (University of Georgia College of Pharmacy)Megan Spradlin (University of Colorado)Hiba Ahmad (University of Colorado)Andrés F Henao-Martínez (University of Colorado)Journal article link: Chastain DB, Spradlin M, Ahmad H, Henao-Martínez AF. Unintended Consequences: Risk of Opportunistic Infections Associated With Long-term Glucocorticoid Therapies in Adults. Clin Infect Dis. 2024;78(4):e37-e56. doi:10.1093/cid/ciad474Journal companion article - Executive summary link: https://academic.oup.com/cid/article/78/4/811/7643625From Clinical Infectious DiseasesEpisodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.comFebrile is produced with support from the Infectious Diseases Society of America (IDSA)

Arsheena Yassin, an ID pharmacist, and Mariya Huralska, an infectious disease fellow, both from Robert Wood Johnson University Hospital, dive into the intricacies of multidrug-resistant gram-negative infections. They discuss a compelling case study showcasing the importance of patient history for effective treatment. Innovations in rapid diagnostics and the significance of tailored antibiotic therapies based on local resistance patterns are highlighted. Moreover, they stress the need for multidisciplinary collaboration to ensure safe transitions from hospital to outpatient care.

Maxime Billick, a recent ID staff graduate set to pursue a Master of Public Health at Harvard, and Isaac Bogoch, an infectious diseases physician at the University of Toronto, dive deep into innovative HIV prevention strategies. They explore the buffet of options available, focusing on PrEP, PEP, and the emerging PIP strategy. The conversation addresses the nuances of personalized risk assessment and the importance of tailored strategies for at-risk populations, especially young men. Their insights shed light on the evolving landscape of HIV prevention.

Experts Daniel Minter and Sarah Doernberg discuss managing Staph aureus bacteremia, including risk stratification, treatment decisions, echocardiograms, and controversies like ID consultation and antibiotic choices. They explore patient evaluation, challenges with persistent cultures, and ongoing studies, offering insights into complex treatment scenarios.

Drs. Maria Gabriela Segura, Misti Ellsworth, and Michael Chang from UTHealth Houston McGovern Medical School and Children’s Memorial Hermann Hospital chat about an unusual pediatric case of fever of unknown origin.Episodes | Consult Notes | Subscribe | Twitter | Merch | febrilepodcast@gmail.comFebrile is produced with support from the Infectious Diseases Society of America (IDSA)

Dr. Matthew Hamill, a researcher from Johns Hopkins University specializing in neurosyphilis, shares his insights on the increasing syphilis rates in the U.S. He discusses the challenges of diagnosing neurosyphilis, particularly the need for lumbar punctures and reliable biomarkers. The conversation highlights innovative treatment strategies, including using intravenous penicillin G and doxycycline post-exposure prophylaxis. Hamill also covers the complexities of managing patients with concurrent HIV and syphilis, emphasizing the need for further research in this critical area.