Febrile 108: StAR: MDR GN
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Aug 12, 2024 Arsheena Yassin, an ID pharmacist, and Mariya Huralska, an infectious disease fellow, both from Robert Wood Johnson University Hospital, dive into the intricacies of multidrug-resistant gram-negative infections. They discuss a compelling case study showcasing the importance of patient history for effective treatment. Innovations in rapid diagnostics and the significance of tailored antibiotic therapies based on local resistance patterns are highlighted. Moreover, they stress the need for multidisciplinary collaboration to ensure safe transitions from hospital to outpatient care.
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Thorough Patient History Matters
- Always obtain a thorough patient history to assess pathogens and resistance risks.
- Consider prior antibiotics, facility exposures, and device presence to tailor treatment.
Evaluate Patient Origin and History
- Assess patient origin: community, hospitals, ICUs, or long-term care to evaluate resistance risk.
- Check prior cultures up to one year and recent travel, especially to regions with known resistance.
Use Local Antibiograms
- Local antibiograms guide empiric antibiotic choice against gram-negative pathogens.
- Knowledge of unit-specific and facility-specific data enhances regimen effectiveness.