🧬The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success.🔬Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸🔗Get your unique referral link here: refer.excedr.com/ZTHETY. Part 2 of 4: Jon Chee hosts Kate Neville, Partner at Marshall Gerstein—a law firm with over 60 years of expertise in delivering sophisticated intellectual property advice and legal services to leading businesses, research institutions, universities, and entrepreneurs worldwide.Kate, an accomplished attorney with a doctoral background in microbiology and immunology, specializes in global patent prosecution and strategic management. With over a decade of experience, she works with biotech startups, big pharma, and non-profits. Kate has been recognized as a "World's Leading Patent Practitioner" by IAM magazine since 2013, an Illinois Super Lawyer since 2018, and is included in The Best Lawyers in America© for Patent Law.Join us this week to hear about:Kate's transition from patent agent to lawyer, highlighting challenges of pursuing a law degree while working full-timeThe culture shock scientists face in law school, adjusting to ambiguity and lack of definitive answersThe extensive reading required in law school compared to scientific literature, requiring a different approachThe collegial culture at Kate's law firm, fostering an environment where former scientists can thriveHow patent law work provides exposure to diverse scientific fields, offering continuous learning opportunitiesPlease enjoy Jon’s conversation with Kate Neville.Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Kate Neville, at these links: https://www.linkedin.com/in/kate-neville-phd/ https://www.marshallip.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Marshall, Gerstein & Borun https://www.marshallip.com/ Business Entities & Their Differences https://www.excedr.com/resources/what-are-the-differences-between-business-entities Intellectual Property 101: Types & Uses https://www.excedr.com/resources/intellectual-property-guide How to Protect Your Intellectual Property in the Life Sciences https://www.excedr.com/resources/how-to-protect-your-intellectual-property Timestamps:00:00 Intro02:24 Kate discusses taking the patent bar and transitioning from patent agent to pursuing law school04:14 Experience of working full-time while attending law school at night06:56 Challenges scientists face when transitioning to law school, particularly dealing with ambiguity09:28 Discussion about the different types of reading required in law school versus scientific papers12:20 Kate describes her law firm's culture and what made her stay throughout her career16:02 Benefits of having broad scientific knowledge and crossdisciplinary experience18:49 Working with scientist clients and keeping up with evolving technologies20:05 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success.Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸Get your unique referral link here: refer.excedr.com/ZTHETY.Part 1 of 4: Jon Chee hosts Kate Neville, Partner at Marshall Gerstein—a law firm with over 60 years of expertise in delivering sophisticated intellectual property advice and legal services to leading businesses, research institutions, universities, and entrepreneurs worldwide.Kate, an accomplished attorney with a doctoral background in microbiology and immunology, specializes in global patent prosecution and strategic management. With over a decade of experience, she works with biotech startups, big pharma, and non-profits. Kate has been recognized as a "World's Leading Patent Practitioner" by IAM magazine since 2013, an Illinois Super Lawyer since 2018, and is included in The Best Lawyers in America© for Patent Law.Join us this week to hear about:How growing up as youngest of six influenced Kate's leadership style of giving autonomy while providing guidanceHow early exposure to science through her father's engineering and a chemistry set ignited her scientific interestsThe research at Michigan's yeast lab and Northwestern's MS research that developed key multitasking abilitiesKate’s unexpected shift from bench science to patent law through colleagues at Marshall GersteinHow career paths in science evolved from strictly academic to broader acceptance of industry and alternative pathsPlease enjoy Jon’s conversation with Kate Neville.Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Kate Neville, at these links: https://www.linkedin.com/in/kate-neville-phd/ https://www.marshallip.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Marshall, Gerstein & Borun https://www.marshallip.com/ Northwestern University https://www.northwestern.edu/ Business Entities & Their Differences https://www.excedr.com/resources/what-are-the-differences-between-business-entities Intellectual Property 101: Types & Uses https://www.excedr.com/resources/intellectual-property-guide How to Protect Your Intellectual Property in the Life Sciences https://www.excedr.com/resources/how-to-protect-your-intellectual-property People Mentioned:Sharon Sintich https://www.linkedin.com/in/sharon-sintich-2033462a/ Stephen Miller https://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=14949 Timestamps:00:00 Intro03:26 Kate's background growing up as the youngest of six children05:36 Kate's leadership style and approach to management07:33 Early exposure to science and developing an interest in chemistry09:27 Exploring different scientific fields in university11:56 Considering career paths and deciding on graduate school12:54 Undergraduate lab experiences and summer research program15:29 Choosing Northwestern for PhD and focus on immunology18:29 Challenges and triumphs during graduate studies21:43 Serendipitous introduction to patent law as a career path25:05 Changing perceptions of non-academic career paths in science27:22 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success.Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸Get your unique referral link here: refer.excedr.com/ZTHETY.Part 4 of 4: Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines.With an MD PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas.Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field.Join us this week to hear about:Founding Verve Therapeutics and pioneering gene editing for cardiovascular diseaseTackling medicine adherence with one-and-done gene therapiesLeadership lessons from starting and scaling biotech startupsHow patient stories inspire innovation in genetic medicineStoke’s vision for genetic medicine and transformative treatments for diseases like Dravet syndromePlease enjoy Jon’s conversation with Barry Ticho.Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Barry Ticho, at these links: https://www.linkedin.com/in/barryticho/ https://www.stoketherapeutics.com/ https://www.vervetherapeutics.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned:Verve Therapeutics: https://www.vervetx.com/Stoke Therapeutics: https://www.stoketherapeutics.com/Google Ventures: https://www.gv.com/Mass General Hospital: https://www.massgeneral.org/Brigham and Women’s Hospital: https://www.brighamandwomens.org/Biogen: https://www.biogen.com/ University of Pennsylvania: https://www.upenn.edu/Gene Editing and Its Impact on Cardiovascular Disease: https://www.health.harvard.edu/heart-health/gene-therapy-for-cardiovascular-diseaseRNA-Based Medicines for Rare Disease Treatment: https://www.nature.com/articles/s41419-022-05075-2Biotech Partnerships With Big Pharma: https://www.excedr.com/blog/how-biotech-partnerships-support-researchBusiness Development in Biotech: https://www.excedr.com/resources/business-development-in-the-life-sciencesBiotech Funding Options: https://www.excedr.com/resources/biotech-startup-funding-optionsScaling Biotechs to Meet Key Milestones with Leasing: https://www.excedr.com/blog/how-leasing-helps-biotechs-scale-efficientlyPeople Mentioned:Sekar Kathiresan: https://www.linkedin.com/in/sekar-sek-kathiresan-3501846/Timestamps:00:00 Intro02:15 Founding Verve Therapeutics over breakfast05:31 Gene editing for cardiovascular disease: The PCSK9 story07:49 Barry’s experience as a first-time CEO12:01 Joining Stoke Therapeutics and exploring RNA-based medicines16:56 Building strong networks and the value of professional connections22:09 Transitioning Stoke from private to public company26:29 Hiring wisely and making difficult decisions quickly30:09 Chief medical officer lessons: patient focus and team amplification33:25 Stoke’s future: Dravet syndrome trials and pipeline expansion35:12 Shouts and advice to younger self37:23 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, shares his extensive experience in RNA medicine and drug development. He discusses the critical transition from academia to industry and the rigorous pharmaceutical standards that govern clinical trials. Ticho emphasizes the importance of patient-centered approaches to therapy and reveals insights on evaluating drug programs. His thoughts on the adaptability required in biotech highlight the challenges and opportunities in the rapidly evolving landscape of modern medicine.

The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success.Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸Get your unique referral link here: refer.excedr.com/ZTHETY.Part 2 of 4: Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines.With an MD-PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas.Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field.Join us this week to hear about:Pioneering research using transparent zebrafish embryos to study cardiac developmentHelping establish the myCHOICE program at University of ChicagoManaging concurrent roles at Harvard Medical School and Mass GeneralGaining invaluable crisis management experience as a pediatric cardiologist leading emergency resuscitationsMaking the strategic career transition to biopharma to combine basic science with clinical workPlease enjoy Jon’s conversation with Barry Ticho.Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Barry Ticho, at these links: https://www.linkedin.com/in/barryticho/ https://www.stoketherapeutics.com/ https://www.vervetherapeutics.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Stoke Therapeutics https://www.stoketherapeutics.com/ Verve Therapeutics https://www.vervetherapeutics.com/ University of Chicago https://www.uchicago.edu/en Harvard Medical School https://hms.harvard.edu/ Boston Children's Hospital https://www.childrenshospital.org/ Massachusetts General Hospital https://www.massgeneral.org/ Northwestern University https://www.northwestern.edu/ How to Spin Out of Academia: https://www.excedr.com/resources/how-to-spin-out-of-academia-and-into-a-startupBreaking into BD as a PhD Student https://www.excedr.com/blog/how-to-break-into-biotech-bd-as-a-phd-student Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-supportMedical Imaging: Modalities & Types of Equipment https://www.excedr.com/blog/medical-imaging-and-radiology-overview People Mentioned:Mark Fishman https://www.linkedin.com/in/mark-fishman-1b1368182/ Timestamps:00:00 Intro 02:16 Transitioning from grad school to Harvard and Boston Children's Hospital04:19 The importance of rotations and exploring different career paths06:48 Fascination with cardiac development: From four cells to a complex organ08:24 Advice on continuous learning and career exploration10:49 The shift in academia: From textbooks to startups12:09 Zebrafish research: Transparent insights into cardiac development14:44 The rewards and challenges of practicing pediatric cardiology16:57 Learning from brilliant colleagues: "Steel sharpens steel"18:18 Avoiding comparison: "Comparison is the thief of joy"20:59 Gaining perspective on emergencies: From cardiac arrests to business crises23:46 The catalyst for transitioning to industry: Combining science and clinical interests26:27 The changing landscape of medicine and the appeal of biopharma27:18 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success.Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸Get your unique referral link here: refer.excedr.com/ZTHETY.Part 1 of 4: Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines.With an MD-PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas.Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field.Join us this week to hear about:Barry's upbringing as one of five boys in a family of physiciansA transformative moment watching a child regain sight that crystallized his career pathHis foundational experiences at Haverford College where he discovered his passion for biologyHis journey through the MD-PhD program at the University of ChicagoHow education, critical thinking, and resilience shaped his leadership approachPlease enjoy Jon’s conversation with Barry Ticho.Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Barry Ticho at these links: https://www.linkedin.com/in/barryticho/ https://www.stoketherapeutics.com/ https://www.vervetherapeutics.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Stoke Therapeutics https://www.stoketherapeutics.com/ Verve Therapeutics https://www.vervetherapeutics.com/ Moderna https://www.modernatx.com/ Pfizer https://www.pfizer.com/ Biogen https://www.biogen.com/ Ophthalmology https://en.wikipedia.org/wiki/Ophthalmology Haverford University https://www.haverford.edu/ University of Chicago https://www.uchicago.edu/en Harvard Medical School https://hms.harvard.edu/ Boston Children's Hospital https://www.childrenshospital.org/ How to Spin Out of Academia: https://www.excedr.com/resources/how-to-spin-out-of-academia-and-into-a-startupPatent Licensing for Biotechs: https://www.excedr.com/resources/how-patent-licensing-worksBiotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-supportPeople Mentioned:Phil Sharp https://en.wikipedia.org/wiki/Phillip_Allen_Sharp Murray Rabinowitz https://www.nasonline.org/wp-content/uploads/2024/06/rabinowitz-murray.pdf Timestamps:00:00 Intro03:04 Barry's background and introduction03:37 Growing up in a family of Holocaust survivor physicians05:29 Four out of five brothers choosing medicine07:14 Early exposure to ophthalmology and patient care09:27 The transformative moment: witnessing a child regain sight12:45 Choosing Haverford and discovering biology14:06 Early laboratory experiences and liberal arts education19:05 The path to University of Chicago's MD-PhD program22:13 First research experiences with RNA and transcription23:55 Graduate school years: freedom and scientific method30:15 Mentorship style and thesis advisor's influence33:05 Leadership lessons from graduate training36:28 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

Part 4 of 4: Jon Chee hosts Chris Moxham, Co-Founder, CEO, and CSO of Transcripta Bio—a pioneering biotech company accelerating drug discovery to improve lives worldwide.With a PhD in Molecular and Cellular Pharmacology from Stony Brook University and over 25 years in drug discovery, Chris brings a wealth of experience. During his two-decade tenure at Eli Lilly, he advanced over 10 molecules into clinical trials across multiple therapeutic areas, spanning both small and large molecule modalities.Chris’s deep expertise and dedication to scientific innovation and team development offer invaluable insights for aspiring biotech leaders.Join us this week to hear about:The complexities of building partnerships with Big Pharma as a startupInsights on developing relationships with larger organizations and patient foundationsThe importance of mutual goals and the art of aligning incentives Transcripta’s progress with their groundbreaking Drug-Gene Atlas, combining genetics, AI, and high-throughput data to redefine the future of drug discoveryPlease enjoy Jon’s conversation with Chris Moxham.Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Chris Moxham, at these links: https://www.linkedin.com/in/christopher-moxham-b8867011/ https://www.transcriptabio.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/Enriched Notes: Topics Mentioned:Eli Lilly & Company: https://www.lilly.com/Transcripta Bio: https://www.transcriptabio.com/Fulcrum Therapeutics: https://www.fulcrumtx.com/NVIDIA: https://www.nvidia.com/en-us/Biotech Partnerships with Big Pharma: https://www.excedr.com/blog/how-biotech-partnerships-support-researchThe Role of BD in the Life Sciences: https://www.excedr.com/resources/business-development-in-the-life-sciencesHow to Break into Biotech BD: https://www.excedr.com/blog/how-to-break-into-biotech-bd-as-a-phd-studentDrug-Gene Atlas: https://www.transcriptabio.com/what-we-doBiotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-supportPeople Mentioned:Efraim Racker: https://efraimracker.library.cornell.edu/Craig Malbon: https://www.pharm.stonybrook.edu/faculty/m/malbonJohn Hadcock: https://www.linkedin.com/in/hadcock/Alan Palkowitz: https://www.linkedin.com/in/alan-palkowitz-7387653/Phil Hipskin: https://www.linkedin.com/in/philip-hipskind-a3b11611/Greg Plowman: https://www.linkedin.com/in/greg-plowman-4177096/Robert Gould: https://www.linkedin.com/in/robertjgouldfulcrum/Jim Collins: https://be.mit.edu/faculty/james-j-collins/Jim Geraghty: https://www.linkedin.com/in/jim-geraghty-7481a262/Alan Ezekowitz: https://www.linkedin.com/in/alan-ezekowitz-54030515/Dave Port: https://www.linkedin.com/in/j-david-port-ab9616b/Timestamps:00:00 Intro and recap02:09 Partnering with Big Pharma and the urgency of startups04:13 Learning business development and building successful partnerships06:18 Understanding stakeholder involvement and approval layers in Big Pharma09:42 Transcripta's collaborations with patient foundations and medical institutions11:31 Ideal partnerships with academic institutions and aligning incentives15:53 The importance of partnership alignment, building trust within the org20:47 Transcripta Bio's vision for the future21:52 Shoutouts and advice to younger self24:45 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success.Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸Get your unique referral link here: refer.excedr.com/ZTHETY.Part 3 of 4: Jon Chee hosts Chris Moxham, Co-Founder, CEO, and CSO of Transcripta Bio—a pioneering biotech company accelerating drug discovery to improve lives worldwide.With a PhD in Molecular and Cellular Pharmacology from Stony Brook University and over 25 years in drug discovery, Chris brings a wealth of experience. During his two-decade tenure at Eli Lilly, he advanced over 10 molecules into clinical trials across multiple therapeutic areas, spanning both small and large molecule modalities.Chris’s deep expertise and dedication to scientific innovation and team development offer invaluable insights for aspiring biotech leaders.Join us this week to hear about:Chris’ transition from Eli Lilly to the startup world, embracing the excitement and uncertainty of a smaller company.Navigating investor relations and honing the skill of translating science into business language.Developing Transcripta Bio’s discovery engine, a scalable approach to drug discovery.Leveraging AI, genetics, and high-throughput data to reduce failure points in drug development.Please enjoy Jon’s conversation with Chris Moxham.Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Chris Moxham, at these links: https://www.linkedin.com/in/christopher-moxham-b8867011/ https://www.transcriptabio.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Wyeth Labs: https://en.wikipedia.org/wiki/WyethEli Lilly & Company: https://www.lilly.com/Fulcrum Therapeutics: https://www.fulcrumtx.com/Transcripta Bio: https://www.transcriptabio.com/Transcripta Bio’s Discovery Engine: https://www.transcriptabio.com/what-we-doHow to Start a Lab: https://www.excedr.com/blog/how-to-start-a-labHow Much Does Lab Space Cost? https://www.excedr.com/blog/how-much-does-lab-space-costBiotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-supportInvestor & Founder Expectations: https://www.excedr.com/resources/investor-founder-expectationsGenerative AI in Drug Discovery: https://www.forbes.com/sites/bernardmarr/2024/06/19/how-generative-ai-is-accelerating-drug-discovery/People Mentioned:Robert Gould: https://www.linkedin.com/in/robertjgouldfulcrum/Timestamps:00:00 Intro02:12 Chris's Transition to Fulcrum: moving from Big Pharma to a smaller Biotech03:42 Mastering investor relations and learning to translate science into business language06:07 Lessons from an IPO and building rapport with investors08:00 Life as CSO of a Public Company and the importance of media training14:57 Building Transcripta Bio’s Discovery Engine and repurposing to accelerate value creation20:08 Leveraging AI in drug discovery and creating new opportunities in CNS and oncology23:52 Scaling drug discovery innovation and building the Drug-Gene Atlas25:09 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

The Biotech Startups Podcast is brought to you by Excedr. Excedr provides life science startups with equipment leases on founder-friendly terms to accelerate R&D and commercialization.Know anyone that needs lab equipment? Join Excedr’s referral program: Give Your Friends $1,000, and Earn $1,000 for Each Qualified Referral 💸.Get your unique referral link by going to: refer.excedr.com/ZTHETY.Part 2 of 4: Jon Chee hosts Chris Moxham, the Co-Founder, CEO, and CSO of Transcripta Bio, a pioneering biotech company charting a faster path in drug discovery to create better lives for people around the world.Chris earned his PhD in Molecular and Cellular Pharmacology at Stony Brook University and is a seasoned veteran with over 25 years of drug discovery experience, having spent two decades at Eli Lilly where he was instrumental in advancing over 10 molecules into clinical trials across multiple therapeutic areas and both small and large molecule modalities. Chris has a wealth of knowledge, and his commitment to both scientific advancement and team growth makes his insights invaluable for aspiring leaders in biotech.Join us this week to hear about:How he got recruited to Eli Lilly through persistent outreach by VP Jose Caro, who recognized Chris's potential How Chris advanced rapidly from obesity research to heading lead generation biology at Lilly IndianapolisHis experience successfully leading a complex $20M lab buildout in NYC after Lilly's ImClone acquisitionTransitioning to biotech as CSO at Fulcrum Therapeutics, where he gained valuable experience in investor relations and helped raise $200M in public marketsWhat it means to serve as CEO developing an innovative "drug machine" platform that combines machine learning with wet lab approaches Please enjoy Jon’s conversation with Chris Moxham.Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Chris Moxham, at these links: https://www.linkedin.com/in/christopher-moxham-b8867011/ https://www.transcriptabio.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Eli Lilly https://en.wikipedia.org/wiki/Eli_Lilly_and_Company ImClone https://en.wikipedia.org/wiki/ImClone_Systems Merck https://en.wikipedia.org/wiki/Merck_%26_Co. Fulcrum Therapeutics https://www.fulcrumtx.com/Marketing & Sales Tools for Biotechs: https://www.excedr.com/blog/marketing-sales-strategies-for-biotechsBiotech Partnerships: How Partnering with Big Pharma Can Support R&D: https://www.excedr.com/blog/how-biotech-partnerships-support-researchHow to Bootstrap a Biotech Tools Startup: https://www.excedr.com/resources/how-to-bootstrap-biotech-startupPeople Mentioned:Jose Caro https://www.linkedin.com/in/josefcaro/ Timestamps:00:49 Intro02:31 "The Power of Persistence in Recruiting" - How Jose Caro's personal outreach convinced Chris to join Eli Lilly05:31 Early days at Lilly: Transitioning from obesity research to high-throughput screening platforms08:18 Leadership evolution: Key lessons in scaling from small teams to managing 45+ scientists12:16 Cultural contrasts: Navigating the different environments between Merck and Eli Lilly14:48 "Making Your Own Opportunities" - How Chris engineered his move to Lilly's NYC labs17:31 Building from the ground up: Creating Quantitative Biology for antibody discovery despite initial resistance20:20 The biotech leap: Transitioning to Fulcrum and experiencing the startup world23:07 Leading a $20M lab buildout: Unexpected challenges in construction and coordination27:23 "Making the trains run on time" - Critical lessons in project management and execution28:50 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

The Biotech Startups Podcast is brought to you by Excedr. Excedr provides life science startups with equipment leases on founder-friendly terms to accelerate R&D and commercialization.Know anyone that needs lab equipment? Join Excedr’s referral program: Give Your Friends $1,000, and Earn $1,000 for Each Qualified Referral 💸.Get your unique referral link by going to: refer.excedr.com/ZTHETY.Part 1 of 4: Jon Chee hosts Chris Moxham, the Co-Founder, CEO, and CSO of Transcripta Bio, a pioneering biotech company charting a faster path in drug discovery to create better lives for people around the world.Chris earned his PhD in Molecular and Cellular Pharmacology at Stony Brook University and is a seasoned veteran with over 25 years of drug discovery experience, having spent two decades at Eli Lilly where he was instrumental in advancing over 10 molecules into clinical trials across multiple therapeutic areas and both small and large molecule modalities. Chris has a wealth of knowledge, and his commitment to both scientific advancement and team growth makes his insights invaluable for aspiring leaders in biotech.Join us this week to hear about:Chris’ childhood growing up on Long Island and his experience with early heart surgery at 12 years oldHow those early experiences shaped his passion for science and medicine His pivotal experiences at Cornell University, where a summer fellowship studying insulin signaling sparked his transition from pre-med to research His groundbreaking PhD research at SUNY Stony Brook developing transgenic mice, leading to publications in Science and Nature The strategic decision to pursue pharmaceutical research over academia, leveraging key connections to launch his industry career at Wyeth His leadership philosophy’s emphasis on respect, teamwork, and balancing immediate results with long-term visionPlease enjoy Jon’s conversation with Chris Moxham.Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Chris Moxham, at these links: https://www.linkedin.com/in/christopher-moxham-b8867011/ https://www.transcriptabio.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Cornell https://www.cornell.edu/ SUNY Stony Brook https://www.stonybrook.edu/ Malbon Laboratory https://www.pharm.stonybrook.edu/faculty_research/directory/m/malbon-craig/laboratory Wyeth https://en.wikipedia.org/wiki/WyethMarketing & Sales Tools for Biotechs: https://www.excedr.com/blog/marketing-sales-strategies-for-biotechsBiotech Partnerships: How Partnering with Big Pharma Can Support R&D: https://www.excedr.com/blog/how-biotech-partnerships-support-researchHow to Bootstrap a Biotech Tools Startup: https://www.excedr.com/resources/how-to-bootstrap-biotech-startupTimestamps:00:49 Intro03:18 Chris's upbringing as the youngest of 7 children on Long Island06:07 The influence of Chris's parents on his leadership style08:20 Family dynamics and expectations growing up in a large household11:06 Choosing Cornell University and the path to pre-med14:30 Securing research opportunities and working with scientific luminaries as an undergraduate16:28 PhD experience at SUNY Stony Brook in Craig Malbon's lab18:36 The impact of mentorship and the drive for impactful research20:55 Craig Malbon's lab structure and management style22:49 Balancing immediate results with long-term planning in research24:35 Transitioning from academia to industry: Chris's first opportunity at WyethThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so