The Biotech Startups Podcast is brought to you by Excedr. Excedr provides life science startups with equipment leases on founder-friendly terms to accelerate R&D and commercialization.Know anyone that needs lab equipment? Join Excedr’s referral program: Give Your Friends $1,000, and Earn $1,000 for Each Qualified Referral 💸.Get your unique referral link by going to: refer.excedr.com/ZTHETY.Part 1 of 4: Jon Chee hosts Chris Moxham, the Co-Founder, CEO, and CSO of Transcripta Bio, a pioneering biotech company charting a faster path in drug discovery to create better lives for people around the world.Chris earned his PhD in Molecular and Cellular Pharmacology at Stony Brook University and is a seasoned veteran with over 25 years of drug discovery experience, having spent two decades at Eli Lilly where he was instrumental in advancing over 10 molecules into clinical trials across multiple therapeutic areas and both small and large molecule modalities. Chris has a wealth of knowledge, and his commitment to both scientific advancement and team growth makes his insights invaluable for aspiring leaders in biotech.Join us this week to hear about:Chris’ childhood growing up on Long Island and his experience with early heart surgery at 12 years oldHow those early experiences shaped his passion for science and medicine His pivotal experiences at Cornell University, where a summer fellowship studying insulin signaling sparked his transition from pre-med to research His groundbreaking PhD research at SUNY Stony Brook developing transgenic mice, leading to publications in Science and Nature The strategic decision to pursue pharmaceutical research over academia, leveraging key connections to launch his industry career at Wyeth His leadership philosophy’s emphasis on respect, teamwork, and balancing immediate results with long-term visionPlease enjoy Jon’s conversation with Chris Moxham.Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Chris Moxham, at these links: https://www.linkedin.com/in/christopher-moxham-b8867011/ https://www.transcriptabio.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Cornell https://www.cornell.edu/ SUNY Stony Brook https://www.stonybrook.edu/ Malbon Laboratory https://www.pharm.stonybrook.edu/faculty_research/directory/m/malbon-craig/laboratory Wyeth https://en.wikipedia.org/wiki/WyethMarketing & Sales Tools for Biotechs: https://www.excedr.com/blog/marketing-sales-strategies-for-biotechsBiotech Partnerships: How Partnering with Big Pharma Can Support R&D: https://www.excedr.com/blog/how-biotech-partnerships-support-researchHow to Bootstrap a Biotech Tools Startup: https://www.excedr.com/resources/how-to-bootstrap-biotech-startupTimestamps:00:49 Intro03:18 Chris's upbringing as the youngest of 7 children on Long Island06:07 The influence of Chris's parents on his leadership style08:20 Family dynamics and expectations growing up in a large household11:06 Choosing Cornell University and the path to pre-med14:30 Securing research opportunities and working with scientific luminaries as an undergraduate16:28 PhD experience at SUNY Stony Brook in Craig Malbon's lab18:36 The impact of mentorship and the drive for impactful research20:55 Craig Malbon's lab structure and management style22:49 Balancing immediate results with long-term planning in research24:35 Transitioning from academia to industry: Chris's first opportunity at WyethThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

The Biotech Startups Podcast is brought to you by Excedr. Excedr provides life science startups with equipment leases on founder-friendly terms to accelerate R&D and commercialization.Know anyone that needs lab equipment? Join Excedr’s referral program: Give Your Friends $1,000, and Earn $1,000 for Each Qualified Referral 💸.Get your unique referral link by going to: refer.excedr.com/ZTHETY.Part 2 of 2: Jon Chee hosts Michael Chen, the Co-Founder and CEO of Nuclera, a biotech company that focuses on bringing rapid protein access to other labs. Michael is a seasoned scientist and entrepreneur who brings a rich background and valuable insights to our podcast. Before co-founding Nuclera, Michael did extensive research as an undergrad student at both Georgia tech and Emory and eventually got his PhD in Chemistry from the University of Cambridge. He has also published nine scientific papers and worked with several leading scientists in their field.Michael’s experiences at the lab bench and as a CEO make this conversation one you don’t want to miss.Join us this week to hear about:Michael’s journey from graduate studies to co-founding NucleraThe unique challenges scientists encounter in the business worldThe importance of adaptability and key lessons in developing/marketing a breakthrough productMichael’s insights into navigating big pharma’s lengthy sales cycles and building successful partnershipsCreating a Go-To-Market (GTM) strategy for a biotech and identifying early adoptersPlease enjoy Jon’s conversation with Michael Chen.Links:Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Michael Chen, at these links: https://www.linkedin.com/in/chenmc/?originalSubdomain=ukhttps://www.nuclera.com/company/board/michael-chen/Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Nuclera: https://www.nuclera.com/Academic Research vs. Industrial Research: https://www.colabra.ai/blog/difference-in-scientific-research-in-academia-vs-industry/Nuclear’s Protein Platform: https://www.nuclera.com/technology/Protein Engineering: https://pmc.ncbi.nlm.nih.gov/articles/PMC4931902/Gene Synthesis: https://www.biomatik.com/blog/the-basics-of-gene-synthesis-a-comprehensive-guide/eProtein Discovery Instrument: https://www.nuclera.com/system/instrument/Go-Market Strategy (GTM): https://www.coursera.org/articles/go-to-market-strategyMarketing & Sales Tools for Biotechs: https://www.excedr.com/blog/marketing-sales-strategies-for-biotechsBiotech Partnerships: How Partnering with Big Pharma Can Support R&D: https://www.excedr.com/blog/how-biotech-partnerships-support-researchHow to Bootstrap a Biotech Tools Startup: https://www.excedr.com/resources/how-to-bootstrap-biotech-startupPeople Mentioned:Timestamps:00:49 Intro02:44 Key differences between graduate studies and entrepreneurship06:21 Succeeding as a startup: idea vs. ability to execute07:43 Nuclera's mission and the importance of de novo DNA synthesis11:09 Where the DNA synthesis market is headed and Nuclera's evolution14:19 Do you want to compete with or empower the protein maker?16:35 Conceptualizing Nuclera's Go-to-Market strategy21:20 Figuring out how to explain and market Nuclera's technology31:52 Building successful partnerships with Big Pharma39:21 Excedr's leading indicators of commercial success45:40 Nuclera's sales enablement and focus on in-person events55:29 Michael's goals for Nuclera and improving operations, sales, marketing, etc.58:31 Shout-outs and advice to younger self01:03:00 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

The Biotech Startups Podcast is brought to you by Excedr. Excedr provides life science startups with equipment leases on founder-friendly terms to accelerate R&D and commercialization.Know anyone that needs lab equipment? Join Excedr’s referral program: Give Your Friends $1,000, and Earn $1,000 for Each Qualified Referral 💸.Get your unique referral link by going to: refer.excedr.com/ZTHETY.Part 1 of 2: Jon Chee hosts our latest guest, Michael Chen, the Co-Founder and CEO of Nuclera, a biotech company that focuses on bringing rapid protein access to other labs. Michael is a seasoned scientist and entrepreneur who brings his rich background and insights to our podcast.Before becoming the Co-Founder of Nuclera, Michael did extensive research as an undergrad student at both Georgia tech and Emory and eventually got his Ph,D in Chemistry from the University of Cambridge. Having worked under some of the leading scientists in their field Michael also has 9 scientific publications to his name. His past experiences both at the lab bench and as a CEO make these episodes ones you don’t want to miss.Join us this week to hear about:The influence of growing up in a data-driven familyLearning to do the damn dishes in the labGetting into the NIH Oxford Cambridge Scholarship ProgramLearning that what got us here won’t get us to where we need to beDifferences between lab work in the UK versus the USPlease enjoy Jon’s conversation with Michael Chen!Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Michael Chen, at these links: https://www.linkedin.com/in/chenmc/?originalSubdomain=ukhttps://www.nuclera.com/company/board/michael-chen/Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/Enriched NotesTopics Mentioned:Emory UniversityNicholas Hud: Origins of Life Research: https://www.storycollider.org/stories/2016/1/4/nick-hud-the-origin-of-life Witchweed: https://en.wikipedia.org/wiki/Striga Rhizosphere: https://en.wikipedia.org/wiki/Rhizosphere NIH Oxford Cambridge Scholars Program: https://oxcam.gpp.nih.gov/ International Institute of Tropical Agriculture: https://www.iita.org/ How Core Lab Support Science Research: https://www.excedr.com/blog/core-labs What is Tech Transfer?: https://www.excedr.com/blog/what-is-tech-transfer What Type of Equipment is Used in Chemistry Research: https://www.excedr.com/blog/what-type-of-equipment-is-used-in-chemistry-research Top Biotech Cities: https://www.excedr.com/blog/top-cities-for-biotech Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-supportPeople Mentioned:Nicholas Hud: https://www.linkedin.com/in/nicholas-hud-754a7517/ Timestamps:00:49 Intro02:44 Growing up in a technical, data-driven family and other early life influences06:24 Choosing appearances over function in elementary school09:52 Family background of Jon Chee and how the Bay Area influenced Excedr11:34 How researching crop science sparked an interest in scientific research16:27 The secret of getting access to Emory's labs via Georgia Tech18:02 Learning to "Do the damn dishes" in the lab at Georgia Tech23:00 Getting his PhD through the NIH Oxford Cambridge Scholarship Program29:01 Challenges and culture shock of doing research in Nigeria32:57 Lessons of resilience entrepreneurs can learn from having limited resources36:31 Running a startup is like spinning lots of plates40:15 "What got us here won't get us there" and knowing when it's time to spend45:49 What it was like working in labs in the UK versus the US48:08 Differences between the UK and US Ph.D tracks52:11 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

Part 4 of 4: Jon Chee hosts our latest guest, Neela Patel, Chief Business Officer at Bonum Therapeutics who are developing protein therapeutics to be used to treat a wide range of diseases. Neela is a seasoned scientist and business development executive with over 30 years of leadership experience in drug discovery and development.Before her time at Bonum Therapeutics Neela worked as the CBO at Good Therapeutics, a biotech company that develops cutting edge protein-based drugs. Her impressive career also includes pivotal roles at Seattle Genetics, AbbVie, Abbott, and Genentech. Her extensive experience as both a scientist and business person give her unique insights you won’t want to miss. Join us this week to hear about:Neela’s transition from AbbVie to Seattle Genetics and business developmentHer meeting with Good Therapeutics CEO and how it changed her career trajectoryHer move to Good Therapeutics as Chief Business Development OfficerNeela’s experience leading Good through its acquisition by Roche, and the importance of strategic deal structuringHer current role as CBO of Bonum Therapeutics and focus on developing cytokine therapies for oncologyPlease enjoy Jon’s conversation with Neela Patel!Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Neela Patel, at these links: https://www.linkedin.com/in/neela-patel-84b144/ https://bonumtx.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Bonum Therapeutics: https://bonumtx.com/Roche: https://www.roche.com/Seattle Genetics (Pfizer): https://www.seagen.com/who-we-are/historyVivo Capital: https://vivocapital.com/Business Development Roles in the Life Sciences: https://www.excedr.com/resources/business-development-in-the-life-sciencesBiotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-supportBuy-side vs. Sell-Side: https://corporatefinanceinstitute.com/resources/career/ma-buy-side-sell-side/Liquidity Events: https://www.investopedia.com/terms/l/liquidity_event.aspWhat Should Investors & Founders Expect From Each Other? https://www.excedr.com/resources/investor-founder-expectationsPeople Mentioned:Greg Hageman: https://medicine.utah.edu/faculty/gregory-s-hagemanDiane Hollenbaugh: https://www.linkedin.com/in/diane-hollenbaugh-b826723/John Mulligan: https://www.linkedin.com/in/john-mulligan-ph-d-5aa5a37/Timestamps: 00:00 Intro02:03 Neela’s motivation to join Good Therapeutics, meeting CEO John Mulligan04:12 Evaluating startup teams and the importance of board alignment07:01 Building trust with the board and John Mulligan’s approach09:24 Structuring the Roche deal for streamlined transition10:46 Good Therapeutics’ culture and team transition to Bonum13:08 Understanding investor motivations and startup priorities14:48 Reflections on shifting from buy-side to sell-side21:46 Bonum’s focus on reducing toxicity in oncology and their clinical pipeline goals27:37 Shout-outs to career mentors and advice for younger self31:02 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

Part 3 of 4: Jon Chee hosts our latest guest, Neela Patel, Chief Business Officer at Bonum Therapeutics who are developing protein therapeutics to be used to treat a wide range of diseases. Neela is a seasoned scientist and business development executive with over 30 years of leadership experience in drug discovery and development.Before her time at Bonum Therapeutics Neela worked as the CBO at Good Therapeutics, a biotech company that develops cutting edge protein-based drugs. Her impressive career also includes pivotal roles at Seattle Genetics, AbbVie, Abbott, and Genentech. Her extensive experience as both a scientist and business person give her unique insights you won’t want to miss. Join us this week to hear about:Neela’s transition from Genentech to Poniard PharmaceuticalsHer collaboration with Greg Hageman on age-related macular degenerationRaising $37 million in Series A financingNeela’s role at Poniard developing pipeline strategy with the head of chemistryHer experiences at Abbott and AbbVie as Director of Global External Research and Search & Evaluation, respectively.Please enjoy Jon’s conversation with Neela Patel!Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Neela Patel, at these links: https://www.linkedin.com/in/neela-patel-84b144/ https://bonumtx.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned:Genentech: https://www.gene.com/Poniard Pharmaceuticals: https://www.linkedin.com/company/poniard-pharmaceuticals/Abbott: https://www.abbott.com/AbbVie: https://www.abbvie.com/Seattle Genetics (Pfizer): https://www.seagen.com/who-we-are/historyPatents Licensing in Biotech: https://www.excedr.com/resources/how-patent-licensing-worksIP Strategy for Biotechs: https://www.excedr.com/resources/intellectual-property-strategy-for-biotechsPartnering with Big Pharma: https://www.excedr.com/blog/how-biotech-partnerships-support-researchAntibody Drug Conjugates (Prime Antibody): https://www.excedr.com/resources/primary-antibodyCorporate Development: https://corporatefinanceinstitute.com/resources/management/corporate-development-guide/In Licensing and Out Licensing: https://www.excedr.com/blog/life-sciences-licensing-agreements-guideBootstrapping Your Biotech: https://www.excedr.com/resources/how-to-bootstrap-biotech-startupPeople Mentioned:Greg Hageman: https://medicine.utah.edu/faculty/gregory-s-hagemanSteve Dedinson: https://www.linkedin.com/in/steve-davidsen-0a65414/ Saul Rosenberg: https://www.linkedin.com/in/saul-rosenberg-638a6910/Timestamps:00:28 Intro01:50 Starting a company after Genentech experience02:36 Greg Hageman’s key gene discovery and securing Series A funding05:32 Developing pipeline strategy at Poniard06:43 Transitioning to BD (Search and Evaluation) at Abbott12:31 Spinning out AbbVie, Neela’s continued focus on Oncology14:58 Fostering innovation and external ideas at AbbVie16:51 Evaluating small companies & the biggest challenge of Search and Evaluation20:13 Key factors for startups looking to partner with big pharma26:32 Transitioning to Seattle Genetics (Seagen) and Corporate Development29:28 Neela’s CorpDev experience, navigating unique challenges34:03 Understanding how to diversify revenue streams and navigate cycles39:01 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

The Biotech Startups Podcast is brought to you by Excedr. Excedr provides life science startups with equipment leases on founder-friendly terms to accelerate R&D and commercialization.Know anyone that needs lab equipment? Join Excedr’s referral program: Give Your Friends $1,000, and Earn $1,000 for Each Qualified Referral 💸.Get your unique referral link by going to: refer.excedr.com/ZTHETY.Part 2 of 4: Jon Chee hosts our latest guest, Neela Patel, Chief Business Officer at Bonum Therapeutics who are developing protein therapeutics to be used to treat a wide range of diseases. Neela is a seasoned scientist and business development executive with over 30 years of leadership experience in drug discovery and development.Before her time at Bonum Therapeutics Neela worked as the CBO at Good Therapeutics, a biotech company that develops cutting edge protein-based drugs. Her impressive career also includes pivotal roles at Seattle Genetics, AbbVie, Abbott, and Genentech. Her extensive experience as both a scientist and business person give her unique insights you won’t want to miss. Join us this week to hear about:Choosing Roche to help make small molecule drugsReflecting on first major management roleThe communication required to work as an advisor to biotech companiesWorking for SUGEN but getting a different job than the one she applied forDealing with the volatility of an acquisitionPlease enjoy Jon’s conversation with Neela Patel!Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Neela Patel, at these links: https://www.linkedin.com/in/neela-patel-84b144/ https://bonumtx.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned:Roche: https://www.roche.com/ Osteoporosis: https://en.wikipedia.org/wiki/Osteoporosis SUGEN-Pfizer: https://en.wikipedia.org/wiki/SUGEN Kinase: https://en.wikipedia.org/wiki/Kinase Pharmacia: https://en.wikipedia.org/wiki/Pharmacia Xylatan: https://www.webmd.com/drugs/2/drug-14256/latanoprost-ophthalmic-eye/details Pfizer and Pharmacia Merger https://www.pfizer.com/about/history/pfizer_pharmacia How to Get Funding for Lab Research: https://www.excedr.com/blog/how-to-get-funding-for-lab-research Microbiology Lab Equipment & Instruments List: https://www.excedr.com/blog/microbiology-lab-equipment-list-to-open-your-new-lab Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-supportTimestamps:00:28 Intro01:52 Choosing Roche because of its pedigree and ability to make small molecule drugs03:34 Leading an academic microbiology lab and learning to work in that environment06:46 Neela asking people for 45 minutes of their time to teach her.what she doesn’t know10:22 Reflecting on her first major management role and some lessons she learned12:53 Working as an adviser to cerebral biotech companies requires great communication14:39 The value of getting to know your professional colleagues on a personal level15:53 Transitioning to SUGEN (Pfizer) but getting a different job than the one she applied for18:41 Being made team lead and having to quickly learn all about the product22:02 The benefits of sales and why the negative stereotypes aren’t always right24:01 What lead to changes in how companies view and treat their acquisitions27:17 How pharma companies view the value of acquired companies technology30:58 Dealing with the volatility of an acquisition and the value of past experiences32:41 Looking back at her time at SUGEN and her accomplishments there37:19 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

Part 1 of 4: Jon Chee hosts our latest guest, Neela Patel, Chief Business Officer at Bonum Therapeutics who are developing protein therapeutics to be used to treat a wide range of diseases. Neela is a seasoned scientist and business development executive with over 30 years of leadership experience in drug discovery and development.Before her time at Bonum Therapeutics Neela worked as the CBO at Good Therapeutics, a biotech company that develops cutting-edge protein-based drugs. Her impressive career also includes pivotal roles at Seattle Genetics, AbbVie, Abbott, and Genentech. Her extensive experience as both a scientist and business person give her unique insights you won’t want to miss. Join us this week to hear about:How a college biology class lead to a Genentech internshipGetting inspired to pursue her PhD Working with influential scientists at DNAXJoining an investment club and pursuing the intersection of science and businessTransitioning out of DNAX and cold calling people for her next opportunityPlease enjoy Jon’s conversation with Neela Patel!Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Neela Patel, at these links: https://www.linkedin.com/in/neela-patel-84b144/ https://bonumtx.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned:Bell Labs: https://en.wikipedia.org/wiki/Bell_Labs Genentech: https://www.gene.com/ AMGEN: https://www.amgen.com/ C. Elegans: https://en.wikipedia.org/wiki/Caenorhabditis_elegans Mutagenesis: https://en.wikipedia.org/wiki/Mutagenesis DNAX Research Institute: https://www.linkedin.com/company/dnax-research-institute/Leptin Receptor: https://en.wikipedia.org/wiki/Leptin_receptor How to Get Funding for Lab Research: https://www.excedr.com/blog/how-to-get-funding-for-lab-research Microbiology Lab Equipment & Instruments List: https://www.excedr.com/blog/microbiology-lab-equipment-list-to-open-your-new-lab Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-supportPeople Mentioned:Sherie Morrison https://www.linkedin.com/in/sherie-morrison-8736217/ Bob Coffman: https://investors.dynavax.com/management/robert-coffman Martin McMahonn: https://www.linkedin.com/in/martin-mcmahon-8643796/ Lewis Lanier https://lanierlab.ucsf.edu/node/3033 Timestamps:00:28 Intro02:31 Growing up in an intellectual household with engaged, socially aware parents07:08 How a college biology class lead to an internship at Genentech10:06 Finding that lab work at Genentech was a perfect balance of togetherness and independence13:05 Similarities between drug discovery and Neela’s cross disciplinary undergrad studies16:18 Getting inspired by Genentech to pursue her PhD at UCLA19:22 Choosing a lab focused on studying C. Elegans 20:48 Looking at the progress of technology and the overall business environment over her career25:18 Dealing with the steep learning curve of a PhD program and learning to not give up27:24 Contemplating her next steps into her professional life and finally settling on DNAX30:14 Working with influential scientists at DNAX Research Institute32:18 Joining an investment club while pursuing the intersection of science and business35:41 Transitioning out of DNAX and manually going through a directory searching for her next opportunity40:02 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

eMalick Njie, CEO of Ecotone AI, is an accomplished scientist with a PhD in Neurobiology who blends AI and healthcare. He discusses Ecotone's innovative use of AI to decode human genomes and target rare diseases. The conversation highlights the adoption of diffusion transformers to model genomes and create synthetic data. eMalick emphasizes intentional company building and shares insights on sustainable growth in biotech. The discussion also touches on the importance of mentorship and self-care in navigating a career in the industry.

The Biotech Startups Podcast is brought to you by Excedr. Excedr provides life science startups with equipment leases on founder-friendly terms to accelerate R&D and commercialization.Know anyone that needs lab equipment? Join Excedr’s referral program: Give Your Friends $1,000, and Earn $1,000 for Each Qualified Referral 💸.Get your unique referral link by going to: refer.excedr.com/ZTHETY.Part 3 of 4: Jon Chee hosts our latest guest, eMalick Njie, CEO of Ecotone AI, a healthcare company that is using AI to find cures for inherited diseases. eMalick is an experienced scientist and entrepreneur who has focused on blending his expertise in neuroscience with his knowledge of AI. In addition to founding two AI companies, Ecotone and Genetic Intelligence, eMalick received his PhD in Neurobiology and Neuroscience from the University of Florida. His extensive and diverse experience from being a postdoctoral fellow at Columbia university to being the CEO of the AI thinktank NeuroStorm makes our conversation with him one you won’t want to miss.Join us this week to hear about:Founding Genetic Intelligence and its mission to combine AI and geneticsChallenges of founding a company, personal sacrifices, and breakthroughs leading to NSF recognitionHow company culture and leadership shifts led eMalick to leave Genetic IntelligenceThe importance of building teams aligned with the original visionDiscovering population genetics through AI and the birth of EcotonePlease enjoy Jon’s conversation with Dr. eMalick Njie!Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Barbara Alcaraz Silva, at these links: https://www.linkedin.com/in/emalick-njie-ph-d-ab82348/ https://ecotone.ai/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Genetic Intelligence (now Genetic Leap): https://www.genetic-leap.com/Neurostorm: https://www.linkedin.com/company/neurostorm-inc/Ecotone AI: https://ecotone.ai/OpenAI: https://openai.com/National Science Foundation (NSF): https://www.nsf.gov/McKinsey & Company: https://www.mckinsey.com/Columbia University: https://www.columbia.edu/Andreessen Horowitz: https://a16z.com/Population Genetics: https://plato.stanford.edu/entries/population-genetics/C. Elegans Research: https://www.ncbi.nlm.nih.gov/books/NBK20086/AI’s Impact in Genetic Research: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10856672/Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-supportUnderstanding Tech Transfer: https://www.excedr.com/blog/what-is-tech-transferIP & Patents in Biotech: https://www.excedr.com/resources/intellectual-property-rights-for-biotechsPeople Mentioned:Bertrand Adanve, PhD: https://www.linkedin.com/in/bertrandadanve/Nathan Clark: https://www.linkedin.com/in/nathan-clark-4b850134/Timestamps:00:28 Introduction01:58 Founding Genetic Intelligence03:23 Early struggles, learning from challenges, and staying lean08:32 The universal approximator and the role of AI at Genetic Intelligence11:56 Early adoption of AI and growing momentum16:30 AI and paradigm shifts18:00 Scaling and growing a team, and the pitfalls of doing so28:38 Building culture and hiring for vision33:38 Launching think-tank Neurostorm and learning from failure37:09 Transition to independent research44:11 Discovering population genetics through AI47:30 The birth of Ecotone and AI transformers51:54 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so

The Biotech Startups Podcast is brought to you by Excedr. Excedr provides life science startups with equipment leases on founder-friendly terms to accelerate R&D and commercialization.Know anyone that needs lab equipment? Join Excedr’s referral program: Give Your Friends $1,000, and Earn $1,000 for Each Qualified Referral 💸.Get your unique referral link by going to: refer.excedr.com/ZTHETY.Part 2 of 4: Jon Chee hosts our latest guest, eMalick Njie, CEO of Ecotone AI, a healthcare company that is using AI to find cures for inherited diseases. eMalick is an experienced scientist and entrepreneur who has focused on blending his expertise in neuroscience with his knowledge of AI. In addition to founding two AI companies, Ecotone and Genetic Intelligence, eMalick received his PhD in Neurobiology and Neuroscience from the University of Florida. His extensive and diverse experience from being a postdoctoral fellow at Columbia university to being the CEO of the AI thinktank NeuroStorm makes our conversation with him one you won’t want to miss.Join us this week to hear about:Answering the question “What is memory?”How playing “Stump the Professor” led eMalick to ColumbiaStudying C Eligans in a sandals-wearing labThe wide applicable uses for AI and ML in researchWanting to help people at scalePlease enjoy Jon’s conversation with Dr. eMalick Njie!Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994Find Our Guest, Barbara Alcaraz Silva, at these links: https://www.linkedin.com/in/emalick-njie-ph-d-ab82348/ https://ecotone.ai/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/joncheehttps://www.excedr.comExcedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes:Topics Mentioned:Alzheimer’s Disease: https://www.alz.org/alzheimers-dementia/what-is-alzheimers Neprilysin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329843/ Amyloid Plaques: https://en.wikipedia.org/wiki/Amyloid_plaques CAR T Therapy: https://www.cancer.org/cancer/managing-cancer/treatment-types/immunotherapy/car-t-cell1.html C Elegans: https://en.wikipedia.org/wiki/Caenorhabditis_elegans Amyloid Hypothesis for Alzheimer’s https://www.cuimc.columbia.edu/news/alzheimers-new-study-supports-amyloid-hypothesis-suggests-alternate-treatment AlexNet: https://en.wikipedia.org/wiki/AlexNet Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-supportPeople Mentioned:Dr. Wolfgang Streit: https://neuroscience.ufl.edu/profile/streit-wolfgang/ Dr. David Borchelt https://www.linkedin.com/in/david-borchelt-42474623/ Martin Chalfie https://chalfielab.biology.columbia.edu/people/martin-chalfieTimestamps:00:28 Intro01:52 Moving to Florida and dealing with massive shifts in weather and culture04:48 Experience working to answer the questions, “What is memory,” 06:21 Studying the other extreme edge of memory, Alzheimer’s disease10:43 Investigating possible plaque busting proteins13:43 Benefits of having more freedom and other differences between MIT and Borchelt's Lab16:25 Playing “Stump The Professor” with Martin Chalfie 20:06 Getting both invited and challenged to write a proposal to study at Columbia25:47 Learning to love the constant surprises and level of people in New York29:46 Going from a lab coat lab to a sandals lab to study C Eligans at Columbia 34:25 Researching neurons responsible for touch sensitivity in C Eligans38:30 Martin Chalfie’s mentorship brilliant mentorship style allowing his students to grow43:43 How a data deluge stemming from one of his experiments started his AI/ML journey 49:53 Choosing the entrepreneurship path and wanting to help people at scale54:27 OutroThe Biotech Startups Podcast is handcrafted by our friends over at: fame.so