Healthcare Unfiltered

Salma Jabbour, MD, Professor and Vice Chair of Radiation Oncology at Rutgers Cancer Institute, provides an invaluable perspective rooted in her extensive experience and passion for radiation oncology. Dr. Jabbour delves into the transformative changes witnessed in radiation oncology over the past two decades, contrasting its trajectory with precision oncology. She shares compelling insights into the PROSPECT trial's innovative approach of omitting radiation therapy entirely for rectal cancer patients, emphasizing the "impressive" results unveiled in the study. Then, the New York Times articles characterizing radiation as "brutal" for patients in this context is considered, and Dr. Jabbour navigates the complexities, challenges, and potential paradigm shifts these findings might signal for the field. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Highlighting the complex and contentious world of non-compete clauses within the medical field, Dr. David Lankford, a pediatric intensivist, made headlines after challenging a non-compete clause in his contract with Lutheran Medical Group in Indiana. His lawsuit not only raises questions about the legality and ethical implications of such clauses, but also tests a new state law regarding physician non-competes. Dr. David Lankford is joined by Alex Pantos, an associate attorney integral to his case. Together, they provide deep insights into the legal intricacies, broader implications for healthcare professionals, and the potential impact of this legal battle on the medical community. The nuances and debates surrounding this pivotal case may reshape the landscape of physician contracts and professional mobility. Read more about the lawsuit. https://www.wfyi.org/news/articles/this-doctors-lawsuit-puts-a-new-physician-noncompete-state-law-to-the-test-heres-whats-at-stake Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Making his return to the show is Dr. Robert Califf, the current FDA Commissioner, this time to break down and offer insights into the Administration’s contentious accelerated approval pathway. Dr. Califf expands on the criticisms and concerns surrounding surrogate endpoints and confirmatory trials within the accelerated approval process, shedding light on the ongoing dialogue between the Administration and manufacturers regarding these crucial trials. He navigates through the intricacies of the Food and Drug Omnibus Reform Act, offering perspectives on the global use of drugs and devices post-negative results in confirmatory trials. Dr. Califf also emphasizes the imperative need for a revamped post-market evidence generation system while exploring various avenues for achieving this critical transformation. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Drs. Hossein Borghaei and Tony Calles dissect the pivotal abstracts and cutting-edge data unveiled at ESMO 2023, spotlighting the transformative landscape of lung cancer treatment. From exploring innovative immunotherapy combinations to the promising prospects of antibody-drug conjugates, they navigate through the complexities of neoadjuvant and adjuvant sequencing, shedding light on optimal therapeutic strategies. With a keen focus on targeted therapies and an array of other compelling studies, Drs. Borghaei and Calles decode the implications of these advancements, offering invaluable insights into reshaping the future of lung cancer care. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Steve Stavs, a “pro biohacker” and “health futurist,” unveils his model to combat chronic diseases by addressing root causes, while exploring Eastern medicine's approach to preventive care and its current standing in research and empirical evidence for complementary interventions. As a pro biohacker, Stavs shares insights on optimizing whole-body performance and health, highlighting the impact of internal and external factors on chronic diseases and differentiating between "getting old" and the process of "aging." With Chadi, he delves into dietary nuances, distinguishing between organic and processed foods, sodas, and their implications for overall health, presenting a holistic view of Chinese and Eastern medicine's potential in fostering a healthier lifestyle. Read more about Steve Stavs. https://stevestavs.com/ Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Ameish Govindarajan, MD, a Hospice and Palliative Medicine fellow at Memorial Sloan Kettering Cancer Center, shares his journey outlined in the Journal of Clinical Oncology's Art of Oncology piece, "Chasing Milestones," which sheds light on his personal experience as a patient diagnosed with stage 4 NSCLC. Dr. Govindarajan shares how this diagnosis influenced his career trajectory, including the pivotal decision to switch oncologists due to a lack of connection with his initial clinician. Together, he and Chadi explore the critical aspects of establishing trust with your healthcare provider and the indicators that signal a strong patient-physician relationship. Delving into his path toward enrolling in an early-phase clinical trial, Dr. Govindarajan provides valuable insights into navigating treatment decisions. Moreover, he discusses how his own care journey has shaped his approach to patient interactions, offering a unique perspective on compassionate and empathetic healthcare delivery. Read Dr. Govindarajan’s publication in JCO. https://ascopubs.org/doi/full/10.1200/JCO.22.01379 Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Chadi is joined by experts Jennifer Wargo, MD, Nazli Dizman, MD, and Sumanta (Monty) Pal, MD, from The University of Texas MD Anderson Cancer Center and City of Hope, to unravel the intricate relationship between the microbiome and cancer. Delving into the historical context and evolution of this connection in oncology, they share insights on manipulating the microbiome and its potential impact on specific cancers, discuss the role of dietary interventions in cancer research and management, and more. Together, they address skepticism surrounding the microbiome's significance in cancer, offering evidence-based arguments that demystify misconceptions and present compelling facts about the microbiome's crucial role in understanding and treating cancer. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Dr. Allison Rosenthal, Assistant Professor of Medicine and a driving force behind Mayo Clinic's Adolescent and Young Adult Cancer Program, candidly shares her personal odyssey as a leukemia survivor during her young adulthood and how this transformative experience steered her career toward advocating for AYA cancer patients. She navigates through complex topics such as survivor guilt, identifying when survivorship begins in the patient journey, and the crucial decision-making between pediatric and adult specialists based on patient age. Dr. Rosenthal also sheds light on the indispensable role of financial counseling and support services for AYA patients while unraveling ongoing research endeavors in this setting. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Dr. Clifford Hudis, the ASCO CEO, shares ASCO's approach to the continued ABIM-MOC saga. With many oncologists expressing their angst about the MOC process, ASCO, under his leadership, approached the situation methodically, sending a survey to its members to quantify the problem and explore next steps. This is the FIRST time the results of this survey are shared publicly. Learn about Dr. Hudis's inspiring career journey, his leadership style, and how he and ASCO are addressing this MOC Dilemma. This is a must-listen episode; be the first to know what has happened within ASCO and what the next steps might be. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Join Chadi as he engages with Petros Grivas, MD, PhD, Professor in the Clinical Research division of Fred Hutchinson Cancer Center, to unravel the groundbreaking updates in bladder cancer revealed at the ESMO Congress. Dr. Grivas provides a comprehensive overview, dissecting the advancements in the realms of muscle invasive bladder cancer, non-muscle invasive bladder cancer, and advanced bladder cancer. Delve into the specifics of EV-302, THOR, and many other studies and gain a deeper understanding of the implications these findings may hold for the future of bladder cancer treatment. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA