Healthcare Unfiltered

Mike Rucker, PhD, a behavioral scientist and organizational psychologist, joins the show to discuss his writing and publishing of the book “The Fun Habit: How the Pursuit of Joy and Wonder Can Change Your Life.” Dr. Rucker explains how you can build having fun into an “actionable and effortless habit” and simultaneously reduce burnout. He shares why Americans have a difficult time enjoying themselves outside of work, what it means to “stop chasing happiness and start having fun,” what kind of societal reset is needed to change the work culture mindset in the US to lead to more productivity, how to “expand your fun file,” and why friendship is the “glue” to good mental hygiene. Read more about Mike Rucker. https://michaelrucker.com/bio/ Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

How do you design clinical trials in the era of precision oncology? Are prospective randomized controlled trials necessary anymore? Drs. Ray Kurzrock, Vivek Subbiah, and Christopher Booth drop the gloves and debate these questions - beginning with the definition of “precision oncology,” what phase the trials should be when initially designing, and whether accelerated approval and surrogate endpoints are truly helping patients in the precision oncology era. The group also analyzes specific examples of approved drugs and whether randomized controlled trials were and would have been good ideas prior to approval. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

In a change-of-pace episode, Chadi has the tables turned on him as he is interviewed by two supporters and reviewers of his new book “Toxic Exposure: The True Story behind the Monsanto Trials and the Search for Justice.” Kelly Ryerson, MBA, GlyphosateGirl.com, and Mikkael Sekeres, author of “Drugs and the FDA: Safety, Efficacy, and the Public's Trust” and “When Blood Breaks Down: Life Lessons from Leukemia,” ask Chadi to comment on why he was chosen as an expert witness, how glyphosate causes cancer and how much exposure is needed to cause lymphoma, why Roundup is able to stay on the market to this day, and what it was like to take the stand and answer questions from the Monsanto lawyers, among so much more. Order your copy of “Toxic Exposure” today. https://www.amazon.com/Toxic-Exposure-behind-Monsanto-Justice/dp/1421445352 Check out Kelly’s blog-turned-website “Glyphosate Facts.” https://glyphosatefacts.com/

In the latest book review, Chadi hosts the authors of the successful expose of his former colleague in “Taking On Big Pharma: Dr. Charles Bennett's Battle.” Julius Getman and Terri LeClercq share how they met Dr. Bennett on a cruise and became interested in his story about his massive achievements and legal charges against him - mishandling government grant money and violating the False Claims Act. They begin with their reasons for believing that the case against Dr. Bennett was baseless and unfounded, what the actual accusations were, and how he ended up facing off against the pharmaceutical and academic worlds. Read more about “Taking On Big Pharma: Dr. Charles Bennett's Battle.” https://www.amazon.com/Taking-Big-Pharma-Bennetts-Childrens-ebook/dp/B0BHTP6P8G Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

A story about adverse reactions, the FDA, the FBI, and patients - Linda Martin, a healthcare executive, shares with Chadi a riveting dialogue about the events in her life that have transpired since she got sick and started taking a standard prescribed antibiotic. Linda tells the story of when and why she was prescribed the antibiotic, how it made her feel worse than before, and how she found similar stories of bad reactions to this drug online. Then, she explains the series of events that led to the stepping-down of the commissioner of the FDA, the FBI’s involvement into investigating drug stock conflicts within the FDA, the stalling of any legal action coming to fruition that may be linked to multiple U.S. presidents, and the suspicious death of the journalist she had been working with to expose the cover-up. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

To better understand the role and importance of Advanced Practice Providers in oncology care, Chadi hosts Sarah Wyman, MSN, ACNP-BC, and Katie Simon, MMSc, PA-C, both co-leads of the APPs on the inpatient malignant hematology services team at Emory University Winship Cancer Institute. They begin by explaining the similar training and skill sets of NPs and PAs, the history of these positions over the past 25 years, and the day-to-day responsibilities for inpatient APPs. Then, they share how discharge planning is handled, the level of autonomy granted to APPs in decision making and test ordering, how doctors relate to APPs in the clinic (and whether there is friction), and their role in initiating end-of-life discussions, among so much more. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

In the world of whole-genome sequencing, do we really need cytogenetics anymore? To answer this question, Chadi brings on two cytogeneticists: Linda Baughn, PhD, and Yassmine Akkari, PhD. They begin by describing their unique career paths to becoming cytogeneticists, their day-to-day responsibilities, and what tests they perform and on what specimens. They then simplify the commonly used assays in their labs, how cytogenetic techniques are evolving (rather than dying), what whole genome sequencing looks like in the future, and topics that cytogeneticists disagree on, among other discussion points. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Today is the day of the official launch of Chadi’s first book “Toxic Exposure: The True Story behind the Monsanto Trials and the Search for Justice.” Throughout the book, Chadi details his experience as an expert physician witness and the true story of the first three litigation trials against Monsanto and their herbicide "Roundup" which is linked to the development of Non-Hodgkin Lymphoma. The special guest on this unique day is the amazing icon and legend Dr. Nassim Nicholas Taleb. Dr. Taleb is beyond introduction; a best selling author of several books that contain concepts being taught in many schools. Dr. Taleb understands risk like no other and he is famous for predicting the Wall Street crash of 2008. Nassim found himself in the crosshairs with Monsanto, a story that he shares on the podcast. Dr. Taleb read “Toxic Exposure,” generously offered his opinion, and shared that he liked it and that he would recommend it to his colleagues and followers. They talk about many things, from GMOs to ghostwriting and some of the finer details of the way Monsanto cherry-picked research to fit its arguments as well as how Chadi handled himself throughout the trials. Order your copy of “Toxic Exposure” today. https://www.amazon.com/Toxic-Exposure-behind-Monsanto-Justice/dp/1421445352 Read some of Dr. Taleb’s articles. https://nntaleb.medium.com Learn more about Dr. Taleb. https://en.wikipedia.org/wiki/Nassim_Nicholas_Taleb Check out his books. https://www.fooledbyrandomness.com

In this special episode, Chadi hosts his previous mentor from his days as a fellow at Northwestern: Martin Tallman, MD, previous president of the American Society of Hematology (ASH) and world renowned leukemia expert. Together, they discuss mentorship and what makes a good mentor, where Dr. Tallman’s interest in leukemia came from and why he decided to begin his career in Seattle, his road to becoming an ASH president and how his day-to-day responsibilities changed after his election, reasons for becoming more active on MedTwitter, and the progression of leukemia treatment in 30+ years, along with much more. Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Nathan Vardi, managing editor at MarketWatch, and author of the new book “For Blood and Money: Billionaires, Biotech, and the Quest for a Blockbuster Drug,” is the guest of honor on today’s show. Nathan divulges on what happened behind closed doors for the creation of BTK inhibitors. Everything at the intersection of Wall Street, investigators, doctors, regulatory agencies, investors, and VC is detailed. He begins by explaining the inspiration to cover this story and how willing individuals were to speak on the record, describes in detail a few of the nuances of and feelings toward specific characters, provides examples of the role that luck plays in cancer drug development, and opines on the FDA’s challenge of approving the right drugs for market, among many other fascinating topics. Read more about “For Blood and Money: Billionaires, Biotech, and the Quest for a Blockbuster Drug.” https://wwnorton.com/books/9780393540956 Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/ Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA