Dare to Disrupt

In this episode of Dare to Disrupt, host Ryan Newman speaks with Robert Chisena, co-founder and CTO of Amplitude Vascular Systems (AVS). AVS is a medical device company focused on safely and effectively treating severely calcified arterial disease. Robert shares his journey from growing up on Long Island in a family of physicians, to discovering his passion for research and entrepreneurship at Penn State, to co-founding an innovative medical device startup.Robert reflects on formative experiences at Penn State, including joining the Schreyer Honors College, diving into biomedical engineering research, and participating in Invent Penn State’s first cohort of the Summer Founders Program. He then traces how his graduate work at the University of Michigan—collaborating closely with physicians—led to the development of AVS’s intravascular lithotripsy technology, a novel approach to restoring blood flow in hardened arteries.Along the way, Robert discusses the challenges of taking research from lab to market, securing venture capital, and convincing physicians of a new device’s safety and efficacy.Later in the episode, Penn State Ph.D. Candidate Marzia Momin joins the conversation. Marzia is working on a neuro-tech startup developing personalized, 3D-printed neural implants for neurological disorders, with applications in therapy and brain-computer interfaces. Marzia recently participated in both the Invent Penn State NSF I-Corps regional short course program and the NSF I-Corps National Teams program. She asks Robert about how to build the best startup team, raising funding as a research-based startup, and what advice he'd give to his younger self.This episode gives an inside look at the intersection of engineering, medicine, and entrepreneurship — and how Penn State alumni are driving innovation in healthcare.Episode Chapters1:30 No avoiding a medical-based career3:25 Choosing and navigating Penn State05:42 Exploring research as an undergrad at Penn State8:24 Launching first medical device startup at Penn State, Summer Founders Program11:54 Moving forward with startup through graduate school at Michigan14:43 Meeting co-founder, learning about the tech behind AVS16:07 The potential to create tremendous impact in cardiovascular disease treatment19:43 Translating and commercializing research out of a university20:49 Where AVS is today, looking to the future22:45 Rapid Fire Round24:27 Student Section25:13 Building the right startup team27:15 Filling in the blanks of business acumen28:04 Advice for securing early funding29:57 Navigating FDA regulations31:02 Advice for aspiring entrepreneursAbout Robert ChisenaRobert Chisena is the co-founder and CTO of AVS. He graduated from the Penn State College of Engineering with a bachelor’s degree in mechanical engineering with honors from the Penn State Schreyer Honors College. Robert went on to receive his Ph.D. in mechanical engineering at the University of Michigan.About Marzia MominMarzia Momin is a Ph.D. candidate in the Engineering Science and Mechanics Department at Penn State, specializing in neural engineering. She is working on a neuro-tech startup developing personalized, 3D-printed neural implants for neurological disorders, with applications in therapy and brain-computer interfaces. Marzia recently participated in both the Invent Penn State NSF I-Corps regional short course program and the NSF I-Corps National Teams program The Dare to Disrupt podcast is made possible by the generous support of the Penn State Smeal College of Business.

AJ Bruno is the founder and CEO of QuotaPath, a leading sales compensation management platform that has secured significant investments, including a $41 million Series B. Serving roughly 1,000 customers, QuotaPath helps organizations align company goals with incentive plans to drive winning sales behaviors.Before QuotaPath, AJ co-founded TrendKite, which was acquired by Cision for $225 million in 2019. He also co-hosts Topline, a podcast on revenue growth and sales leadership.In this episode, AJ shares the stories behind launching TrendKite and QuotaPath, his passion for flying, and his perspective on integrating AI into workflows as a founder. He reflects on his days as a Penn State student, studying abroad in Italy, his first job at Meltwater, and how a terrible boss inspired him to start his first company.Later in the episode, recent Penn State grad Paul Allen joins the conversation. A participant in the Invent Penn State Summer Founders Program, Paul asks AJ for advice on raising venture capital, making first hires, and navigating the challenges of early-stage entrepreneurship.Episode Chapters02:13 - 07:06 Growing up in Pittsburgh, acting and flying07:06 - 12:17 Choosing Penn State, squash club, studying abroad12:17 - 15:38 First entrepreneurial venture at Penn State15:38 - 22:48 First job in sales, advice to students and parents22:48 - 29:15 Terrible boss as a catalyst for TrendKite29:15 - 33:02 The problem that inspired the launch of QuotaPath33:02 - 40:33 Navigating AI and future of QuotaPath40:33 - 43:51 The crazy story that led to AJ launching a podcast43:51 - 45:24 Rapid Fire Insights45:24 - 55:20 Recent student Paul Allen interviews AJAbout AJ BrunoAJ Bruno is founder and CEO of QuotaPath. He graduated from the Penn State Schreyer Honors College with a bachelor’s degree in economics from the Smeal College of Business in 2007.About Paul AllenPaul is a spring 2025 graduate of the Penn State College of Engineering. He completed the 2025 Invent Penn State Summer Founders Program with his startup, Reflex Technologies. Reflex is building a wearable electromyography (EMG) sensor that provides real-time muscle activation and fatigue insights to athletes and trainers. The Dare to Disrupt podcast is made possible by the generous support of the Penn State Smeal College of Business.

Anne Pauley is a technical program manager at Google, implementing world-class manufacturing processes for the Google Pixel smartphone. In this episode, Anne shares her expansive experience in additive manufacturing, industrial art, and engineering design, as well as a mission to bring more diversity to the hands-on fabrication space.In this episode, Anne shares her journey from Penn State to leading innovative projects at Google. She discusses her dual interests in mechanical engineering and music technology, her experiences at Penn State, and her professional journey through various companies including Disney, Meta, and Google. Through her work creating massive art pieces with the Flaming Lotus Girls art collective and her personal art studio, Cognitive Flow Design, she aims to disrupt the industrial design industry. Toward the end of the episode, Penn State rising senior Irena Potochny joins the conversation. Irena and Anne discuss the challenges and opportunities for women in engineering, and Anne offers advice for future engineers.Episode Chapters0:00 - 3:58 Growing up in State College3:58 - 8:03 Pursuing engineering and music at Penn State8:03 - 9:09 Participating in the Humanitarian Engineering and Social Entrepreneurship (HESE) program at Penn State9:09 - 12:02 Understanding additive manufacturing12:02 - 13:17 Experience in the Blue Band13:17 - 16:47 Pursuing a Master's Degree at Penn State in mechanical engineering16:47 - 18:20 Building animatronics at Disney; learning about different types of companies18:20 - 19:26 Working at Meta's Reality Labs, becoming a technical program manager19:26 - 23:21 Innovating the Google Pixel phone, the complexities of designing consumer products23:21 - 24:12 Achieving sustainability in manufacturing through 3D printing24:12 - 29:39 Creating large-scale art installations for Burning Man with Flaming Lotus Girls29:39 - 31:17 Creating innovative light art projects through her studio Creative Flow Design31:17 - 40:08 Student section21:17 -34:38 More efficiently using recycled materials for art34:38 - 36:15 Advice for women entering the engineering field36:15 - 37:07 Selecting materials for art projects37:07 - 39:30 What classes Anne would want to come back to Penn State to takeAbout Anne PauleyAnne is a technical program manager at Google. Anne graduated from the Penn State Schreyer Honors College with dual bachelor’s degrees in mechanical engineering (College of Engineering) and music technology (College of Arts and Architecture) before pursuing a master’s degree with a focus on mechanical design, mechatronics and additive manufacturing. About Irena PotochnyIrena is a rising fourth-year materials science and engineering student with a minor in sustainability leadership. She is a past participant of the Idea TestLab program at Happy Valley LaunchBox powered by PNC Bank. Irena created an upcycled fashion show as a capstone project, and she is in the process of starting a small business to sell upcycled products. Post-graduation, she plans to pursue a master's degree in textile engineering. The Dare to Disrupt podcast is made possible by the generous support of the Penn State Smeal College of Business.

Sean Griffey and Ryan Willumson are the co-founders of Industry Dive, a digital media company delivering business news and original analysis through targeted newsletters. Covering sectors like healthcare, energy, transportation, retail, and more, Industry Dive serves over 14 million North American users and partners with major clients including Amazon, Salesforce, Uber, IBM, and American Express. The company is known for producing some of the most respected journalism in the business world. In this episode, Sean and Ryan discuss how they met while working at FierceMarkets, a B2B e-media startup, and what inspired them to launch Industry Dive. They share how they bootstrapped the company, built a loyal audience, and grew the business to $100 million in revenue before its acquisition by Informa in September 2022. The Dare to Disrupt podcast is made possible by the generous support of the Penn State Smeal College of Business.

Dare to Disrupt LIVE: Innovating the Future of EV Infrastructure brought together three Penn State alumni at the forefront of the electric vehicle revolution to explore the challenges and opportunities shaping the industry's future. This live episode features an engaging discussion with Benjamin Birnbaum (Keyframe, Terawatt), Zander Isaacson (Xeal), and Diallo Powell (Stak Mobility) as they share insights on EV infrastructure, charging technology, and the role of innovation in accelerating adoption. Whether you're an entrepreneur, investor, or EV enthusiast, this conversation offers a rare opportunity to hear directly from industry leaders driving the future of electric transportation. Benjamin Birnbaum is co-founder and partner at Keyframe, a New York City-based investment firm focused on the energy transition’s impact on industry. Prior to Keyframe, he founded Terawatt, an infrastructure developer, owner, and operator for large-scale EV charging. Terawatt has raised over $1 billion and provides fleet charging for companies like Pepsi and Waymo. Ben is a graduate of the Penn State Smeal College of Business. Diallo Powell is co-founder and CEO of Stak Mobility, which addresses urban mobility challenges with an automated vertical carousel system for vehicle storage and EV charging—combining smart software with space-saving infrastructure. Diallo graduated from the Penn State College of the Liberal Arts. Zander Isaacson is co-founder and CEO of Xeal, a technology-first EV charging company at the intersection of proptech, energy, and the Internet of Things. Xeal partners with more than 70 of the largest real estate companies nationwide. Zander, a Penn State Smeal College of Business graduate, is also our first-ever repeat guest on Dare to Disrupt. Together, Ben, Diallo, and Zander discuss the broader trends and challenges shaping the EV landscape, how their companies are uniquely tackling these issues, strategies for scaling and financing capital-intensive projects, and their predictions for the future of the industry. Episode Chapters 0:00 - 7:09 The EV industry landscape at large, building infrastructure 7:09 - 16:35 Fleet vs. consumer charging, offline charging, and urban charging 16:35 - 27:10 Scaling capital-intensive companies 27:10 - 36:38 The future of the EV industry 36:38 - 45:19 Advice for entrepreneurs entering this industry 45:19 - 50:33 Audience questions Dare to Disrupt is made possible by the generous support of the Penn State Smeal College of Business. The Dare to Disrupt podcast is made possible by the generous support of the Penn State Smeal College of Business.

Birgitt Boschitsch is the co-founder and CEO of spotLESS Materials, an advanced materials company and Penn State spinoff commercializing highly repellent anti-fouling coatings.  In this episode, Birgitt shares how her passion for helping others through research led to her co-founding spotLESS Materials. She discusses her formative experiences, academic challenges, and the pivotal moments that shaped her career path, including her time at Princeton and her decision to pursue graduate studies at Penn State.  She discusses the original inspiration behind the idea for a toilet coating that repels sticky waste, as well as the challenges of transitioning from lab work to startup life. She shares the importance of community support and the impact of media exposure on sales. The Dare to Disrupt podcast is made possible by the generous support of the Penn State Smeal College of Business.

Sisters Cory Varona-Corniel and Nicol Varona Cancelmo are the cofounders of OCOA, providing clean, natural, curly haircare products. In this episode, Nicol and Cory share their inspiring journey from the Dominican Republic to the United States. They detail how they were able to overcome language barriers, build a community at Penn State Berks, and launch into each of their professional careers. They discuss their close bond as sisters, the influence of their family, and how their family roots in the Dominican Republic inspired not only the name but also the ingredients and mission behind OCOA. The Dare to Disrupt podcast is made possible by the generous support of the Penn State Smeal College of Business.

Paul Suhey is the Chief Operating Officer and co-founder of Revel, where he drives the company’s mission to accelerate electric vehicle adoption in U.S. cities by focusing on fast-charging infrastructure. In this episode, Paul shares Revel's journey from its beginnings as an urban electric moped sharing startup to a company focused on building the EV charging infrastructure for the largest cities across the US.  At the end of the episode, current Penn State student Michael Slesarevich joins the conversation. Michael is a first-year mechanical engineering student and the founder of Shade Shift, an electrically controlled variable tint film for vehicles. He recently participated in the Happy Valley LaunchBox powered by PNC Bank Idea TestLab, and is a member of the Penn State Car Club. Michael and Paul discuss overcoming the challenge of securing that first investment, as well as how Revel views would-be competitors as potential future customers. The Dare to Disrupt podcast is made possible by the generous support of the Penn State Smeal College of Business.

Gary Brandeis is the CEO and Co-Founder of Scholar Hotels, a hotel ownership and management group with a focus on properties close to major college and university campuses. Gary acquired his first hotel in 2006 and has since been directly involved in the hospitality business as an investor, developer, and manager. Scholar Hotels made its State College debut in March 2017, when it opened the 165-room Hyatt Place State College. Since then, the group has expanded its State College properties to include the Scholar Hotel, the Courtyard by Marriott, the Residence Inn by Marriott, The Penn Stater Hotel & Conference Center, and, of course, The Nittany Lion Inn. Gary graduated from the Penn State Smeal College of Business with a degree in accounting.  In this live episode recorded in the 1855 Lounge at The Nittany Lion Inn, Gary shares how his background in accounting prepared him for the real estate industry, the details of the Inn's renovation, as well as how he thinks about and manages risk. The Dare to Disrupt podcast is made possible by the generous support of the Penn State Smeal College of Business.

Mario Ciabarra is the CEO and founder of Quantum Metric, a customer-centered digital analytics platform for today's leading enterprise organizations. Since its founding in 2015, Quantum Metric's approach to in-depth customer understanding has seen rapid adoption from Fortune 500 companies. The world's largest airline, telco, retailer, healthcare, bank, and more have adopted the Quantum Metric platform. In this episode, Mario shares valuable lessons on integrity and communication learned during his college years. He discusses launching and exiting his first startup in just 11 months, a success that allowed him to briefly retire and travel the world. Mario also explains how Quantum Metric enhances visibility into customer friction points for major industry leaders and how the company integrates generative AI into its solutions. Finally, he reflects on how he approaches building his legacy. The Dare to Disrupt podcast is made possible by the generous support of the Penn State Smeal College of Business.