This Week in Virology

Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Kathy Spindler The TWiVerers answer listener email about genetically modified chickens, a hendra vaccine for horses, online education, curing color blindness, Roosevelt and polio, Th cells, and much more. Links for this episode: TWiV 116: Cocaine, colonies, and chickens Glofish Recombinant Hendra vaccine Gene therapy for color blindness (Nature) FDR, polio, and Guillain-Barré Transcript of TWiV 197: Philip Marcus (pdf) TWiV 10: Bats, elephants, and AIDS TWiM 6: Phage therapy TWiP 47: For whom the trich tolls Viruses of protozoan parasites (virology blog) Long in the tooth Transcript of 'How to read a science paper' (pdf) FEMA disaster preparedness courses Letters read on TWiV 212 Weekly Science Picks Rich - OverviewAlan - Notes towards the complete works of ShakespeareKathy - Correlation vs. Causation (#1, #2, #3)Vincent - Periodically inspired Listener Pick of the Week Mark - Life of a Nature paperRicardo - Things don't go viral Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Kathy Spindler The TWiV four discuss an mRNA-based influenza vaccine, and a phage tubulin that forms a filamentous array in the host cell that is needed for positioning viral DNA. Links for this episode: mRNA vaccine against influenza (Nat Biotech) Phage tubulin assembles dynamic filaments (Cell) Viral skeleton (The Scientist) Not unorganized bags of enzymes (TWiM 28) Bacterial cytoskeleton (FEMS Micro Rev) Triangulation number (jpg) Letters read on TWiV 211 Weekly Science Picks Rich - Ocean Global Shark TrackerAlan - The Field Book ProjectKathy - How to manipulate an army of zombiesVincent - Science sculpture Listener Pick of the Week Stephen - WEHI.TV Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Rich Condit, Dickson Despommier, Alan Dove, and Kathy Spindler The complete TWiV team reviews identification of the cell receptor for hepatitis B and D viruses, and the cell enzyme that cleaves the genome-linked protein from picornaviral RNA. Links for this episode: HBV and HDV cell receptor (eLIFE) Getting to grips with hepatitis (eLIFE) Sodium taurocholate Poliovirus hijacks DNA repair enzyme (PNAS) Letters read on TWiV 210 Weekly Science Picks Rich - Vendée GlobeDickson - Earth at nightAlan - Trophée Jules VerneKathy - Science cookiesVincent - Trilobite Glassworks Listener Pick of the Week Ken - Spanish flu pandemic model (teacher's guide)Jim - Santa Cruz Science Communication Program (also see SHERP) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Vincent, Dickson, Alan, and Kathy answer listener email about deformed wing virus, West Nile virus, FluMist, influenza in Canada, viruses and the tree of life, and more. Links for this episode: Postcard from the ultimate student athlete (pdf) Fidelity of protein synthesis (Biochemistry, 5th ed.) Letters read on TWiV 209 Weekly Science Picks Dickson - Cassini web site and Mars reconnaissance orbiterAlan - OneZoom Tree of LifeKathy - Viral tumor suppressor structure (Cell)Vincent - Spot the Station Listener Pick of the Week Ricardo - Once upon a time: The possible story of virusesJim - Encode, myIDP, Experiment Reproduction podcastsMark - MoMath Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello and Jon Yewdell Vincent and is joined by special guest Jon Yewdell to discuss solutions for ending the current crisis in American biomedical research. Links for this episode: How to succeed in science: Taking the plunge (Nat Rev Mol Cell Biol) How to succeed in science: Making discoveries (Nat Rev Mol Cell Biol) How to succeed in science (YouTube) Resources for graduate students and postdocs Science career cartoons by Alexander Dent Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Matt Frieman, and Kathy Spindler Vincent, Alan, Matt, and Kathy review the use of silk to stabilize antibiotics and a viral vaccine, and an impaired-fidelity vaccine against SARS coronavirus. Links for this episode: Silk stabilization of antibiotics and vaccines (PNAS) Impaired-fidelity coronavirus vaccine (Nature Medicine) Select agent status and SARS therapies (Spoonful of Medicine) Letters read on TWiV 207 Weekly Science Picks Matt - Virus-associated pyramids (slide #11)Alan - Similarities of wave behavior (YouTube)Kathy - The glass transitionVincent - US cattle country in uproar at virus lab plans (BBC) Listener Pick of the Week Ricardo - Blackawton bees and Science is for everyone (TED)Tony - Biophilia by Bjork Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Kathy Spindler Vincent, Alan, Dickson, and Kathy discuss how the innate immune response to viral infection influences the production of pluripotent stem cells, and the diverse mobilome of giant viruses. Links for this episode: Innate immunity and nuclear reprogramming (Cell) Viruses affect cell reprogramming (The Scientist) Cell-penetrating peptides (Trends Mol Med) Provirophages and transpovirons (PNAS) Organic Lake photo and map Letters read on TWiV 206 Weekly Science Picks Alan - Locust by Jeffery A. LockwoodDickson - Nikon Small World Contest 2012Kathy - Influenza EncyclopediaVincent - Dengue fever sweeps India (NY Times) Listener Pick of the Week Allison - Fred Guterl on The Daily Show Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv.

Hosts: Vincent Racaniello and Harmit Malik Vincent is joined by special guest Harmit Malik to discuss his work on the evolution of genetic conflict. Links for this episode: Harmit on YouTube Retroviruses and mammalian placentation (PNAS) Paleovirology (Curr Opin Virol) Evolution among AIM2-like receptors (J Exp Med) Poxvirus genomic accordions (Cell) Letters read on TWiV 205 Weekly Science Picks Vincent - Candidates' answers to science questions Listener Pick of the Week Steve - Mural of Henrietta Lacks story (Microsoft Silverlight required) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Matt Frieman, and Kathy Spindler Vincent, Alan, Matt and Kathy review isolation of a new coronavirus from two patients in the Middle East, and expansion of the enteric virome during simian AIDS. Subscribe to TWiV (free) in iTunes, at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app. Links for this episode: Novel coronavirus (virology blog one, two) PCR assay for novel CoV (Eurosurveillance) Isolation of novel coronavirus (NEJM) SARS CoV now a select agent (Federal Register, pdf) My Sharona Pathogenic SIV infection associated with expansion of gut virome (Cell) Letters read on TWiV 204 Weekly Science Picks Alan - Map of the WindMatt - Dark Side of the Earth; Insensitive guide to thriving in your Ph.D.; Gary Vanerchuck (YouTube)Kathy - How much does a shadow weigh? and Slinky drop answerVincent - A Parasite's Parasites; All the cool kids are on arXiv Listener Pick of the Week Nissin - Jungle Jim (1948) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, and Mark Challberg Vincent and Rich meet up with Mark Challberg to talk about his scientific career studying viral DNA replication, and his transition to an NIH Program Officer. Subscribe to TWiV (free) in iTunes, at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app. Links for this episode: Purification of vaccinia virus DNA polymerase (J Biol Chem) Adenovirus DNA replication in vitro (PNAS) Herpes simplex viral genes required for DNA synthesis (J Virol) Letters read on TWiV 203 Weekly Science Picks Rich - Mattel Hot Wheels Curiosity RoverVincent - Should H5N1 Moratorium End? Listener Pick of the Week Claudio - DIY lab equipment (Ars Technica) and DIY Bio Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.