This Week in Virology

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Recording together for the first time, the TWiV team celebrates their 300th recording at the American Society for Microbiology headquarters in Washington, DC, where Vincent speaks with Dickson, Alan, Rich, and Kathy about their careers in science. Links for this episode So Happy Together (The Turtles) Viral Hemorrhagic Fever Consortium Support Kenema VHFC program Letters read on TWiV 298 Video of this episode - view at YouTube Weekly Science Picks Alan - The Internet's Original SinDickson - PlacidcoyoteRich - Scientific Method, Grail StyleKathy - Viruses Throughout Life and TimeVincent - ALS Ice Bucket Challenge Listener Pick of the Week Jim - iBiologyVictoria - Images of ScienceMehul/Walt - Calling the Shots Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Host: Vincent Racaniello Guests: Marshall Bloom, Sonja Best, and Byron Caughey Vincent visits the Rocky Mountain Laboratories in Hamilton, Montana and speaks with Marshall, Sonja, and Byron about their work on tick-born flaviviruses, innate immunity, and prion diseases. Links for this episode Rocky Mountain Laboratories, NIH Flavivirus persistence (Path Dis) Flaviviruses antagonize IRF1 (J Imm) Prion test using nasal brushings (NEJM) Video of this episode - view at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler The TWiV gang answer follow-up questions about the Ebola virus outbreak in West Africa, then discuss treatment of disseminated multiple myeloma with oncolytic measles virus. Links for this episode Use of unregistered interventions for Ebola virus disease (WHO) Response to anthrax and H5N1 incidents (CDC) Remission of disseminated cancer after treatment with oncolytic measles virus (Mayo Clin Proc) New viruses for cancer therapy (Nat Rev Micro) Cattaneo on TWiV Image credit Letters read on TWiV 298 Weekly Science Picks Alan - WTF, Evolution?! by Mara GrunbaumRich - Cold Spring Harbor Oral History CollectionKathy - Inside insidesVincent - Going Viral (Rocky Mountain Ballet Theatre) Listener Pick of the Week Kim - Nobel Prize PodcastsJohnye - The Planet is FineJennie - Counter-Zombie Dominance Plan (pdf) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler The TWiVites present an all-ebolavirus episode, tackling virology, epidemiology, and approaches to prevention and cure that are in the pipeline. Links for this episode Risks and benefits of gain-of-function experiments (mBio) Scientists for Science US Policy for oversight of DURC (pdf) US framework for guiding H5N1 transmission expts (pdf) Extra oversight for H7N9 experiments (Science) TWiV 283: No Reston for the weary Is it Ebolavirus or Ebola virus? (virology blog) Ebola virus disease update (WHO) Ebola virus disease FAQ (WHO) Ebola hemorrhagic fever (CDC) Ebola virus disease: ecology meets economy (PLoS NTD) 2014 Ebola virus outbreak (J Gen Virol) 2014 Ebola virus outbreak (MMWR) If Ebola virus came to the US (Vox) Zaire ebolavirus in West Africa (interview with Tom Solomon) Why Ebola patients were brought to US (Wash Post) Experimental treatment and vaccines for Ebola (CDC) Aerosol transmission of Reston virus (Sci Rep) Ebola - A growing threat? (NEJM) On the cusp of Ebola vaccine (Know) Ebolavirus vaccines and antivirals (virology blog) Immune responses to Ebolavirus infection (Exp Rev Clin Imm) Antibody therapy for Ebola (Hum Vacc Immunother) Plant derived monoclonals protect macaques from Ebolavirus (PNAS) Anti-ebolavirus monoclonal cocktail (Sci Trans Med) ZMapp info sheet (pdf) ZMapp PR (pdf) High tech treatment for Ebola (ArsTechnica) ZMapp protects macaques (Sci Rep) Letters read on TWiV 297 Weekly Science Picks Alan - Historical perspective on Ebola (Tara C Smith)Rich - Tell the negative committee to shut up (Fanuel Muindi)Kathy - Art of Night (Vimeo)Vincent - Is Ebola virus going to kill me? (John Skylar) Listener Pick of the Week Peter - Dr. Michael Saag interview by Dr. Virginia CampbellDavid - PI Predictor (app, article, publication) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Host: Vincent Racaniello Guest: Linfa Wang Vincent visits the Australian Animal Health Laboratory in Geelong, Australia and speaks with Linfa about his work on bats and bat viruses. Links for this episode Hendra virus vaccine (Emer Inf Dis) Comparison of bat genomes (Science) Endogenous retroviruses in bats (Retrovirol) The Bat Pack Bats in Geelong (YouTube) Video of this episode - view at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit The TWiVome discusses an miRNA based strategy to mitigate risk of gain of function studies, and identification of a second receptor required for Lassa virus entry. Links for this episode miRNA strategy to minimize risk (Nat BioT) NIH Office of Science Policy NIH recombinant DNA guidelines Second receptor for Lassa virus entry (Science) Lassa fever (Wikipedia) Fever! The discovery of Lassa virus (TWiV 9) Letters read on TWiV 294 Weekly Science Picks Alan - Nicky Bay macrophotography (Flickr)Rich - FASEB Third annual BioArt competitionVincent - Up Close podcast (vrr episode)Dickson - Science fun (YouTube) Listener Pick of the Week Mark Martin - Average bacteriophageKonrad - Scholarpedia Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit The TWiV team reviews the discovery of old vials of smallpox virus at NIH, anthrax and influenza mishaps at CDC, the baby who was not cured of HIV, Cambridge Working Group, and sacking of NSABB members. Links for this episode Newly discovered smallpox (CDC) Infectious smallpox in FDA storage (FDA) Report on potential anthrax exposure (pdf, CDC) CDC Director on unsafe practices (NY Times) HIV returns to baby (NY Times) Original HIV baby cured article (NEJM) Cambridge Working Group NSABB members released (ScienceInsider) Letters read on TWiV 294 Weekly Science Picks Alan - OptivisorRich - Noller lab ribosome moviesVincent - Creepy dreadful wonderful parasitesDickson - National Center for Science Education Listener Pick of the Week Mark - The Machinery of Life by David GoodsellBasel - iBioEducation Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Host: Vincent Racaniello Guests: Melissa Churchill, Alex Khromykh, Gilda Tachedjian, and Paul Young Vincent visits Melbourne, Australia and speaks with Melissa, Alex, Gilda, and Paul about their work on HIV infection of the central nervous system, West Nile virus, microbicides for HIV, and the Koala retrovirus. Links for this episode Where does HIV hide? (Curr Op HIV AIDS) Subgenomic flavivirus RNA (Viruses) Vaginal lactic acid and HIV (J Antimicro Chem) Koala retroviruses (Retrovirology) Coming soon - Video of this episode at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Host: Vincent Racaniello Guests: Wade Blair, Matt Dickson, Nicole Kallewaard-Lelay, and Ken Miller Vincent visits Medimmune and speaks with Wade, Matt, Nicole, and Ken about why they work in industry and their daily roles in a biotechnology company. Links for this episode Medimmune, LLC Medimmune on Twitter Medimmune history and products Video of this episode - view at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Clodagh O'Shea and Ron Fouchier Vincent, Rich, and Kathy and their guests Clodagh and Ron recorded this episode at the 33rd annual meeting of the American Society for Virology at Colorado State University in Ft. Collins, Colorado. Links for this episode Viral polymer that inactivates tumor suppressors (Cell) Mutations driving airborne transmission of influenza H5N1 virus (Cell) Transmission of influenza H7N1 virus in ferrets (J Virol) Ron Fouchier on TWiV #177 Photo credit: Matt Evans Thanks to David Quammen for the title Video of this episode - view at YouTube Weekly Science Picks Rich - No sexual transmission of HCV (Am J Gastro)Vincent - Made with code (blog post)Kathy - Beautiful math images (and 50 Visions of Mathematics) Listener Pick of the Week Jon - Advances in Life Sciences winners (YouTube)Dave - Adam Ruben Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv