The Feldman Protocol

In this episode of The Feldman Protocol, a core question hangs over the conversation: how did so many clinicians and patients miss low-carb interventions for so long? Dave sits down with Doug Reynolds, founder of Low Carb USA and president of the Society of Metabolic Health Practitioners, as the guest makes the case for carbohydrate reduction in chronic disease, practitioner education gaps, cultural food traditions, patient-driven change, conference-based knowledge sharing, and why engineers often follow data over authority.🔥 This episode is sponsored by us -- Own Your Labs `http://ownyourlabs.com` -- private blood testing services.🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters3:02 – Fat, food, and first doubts7:05 – Preserving meat traditions11:02 – Cooking as commitment15:03 – Culture vs convenience19:02 – Career detours and Amway24:03 – Discovering ketones29:02 – First ribeye moment34:02 – Engineers and data trust39:05 – Questioning guidelines45:02 – Forums over authority51:21 – Conferences as catalysts57:10 – Practitioner hesitation1:02:28 – Patients leading change1:08:15 – Education gaps in care1:15:40 – Cultural resistance1:21:39 – Scaling conferences1:27:10 – Screening ideas1:33:00 – Community momentum1:39:40 – Measuring success1:45:20 – Clinical anecdotes1:51:21 – Sharing unfinished work1:56:30 – Patient empowerment2:01:39 – Insulin outcomes shift2:02:28 – Lifestyle over mandates2:03:56 – Why the message spreads#FeldmanProtocol #DaveFeldman #DougReynolds #LowCarbUSA #MetabolicHealth #PodcastInterview #HealthDiscussion #SciencePodcast #NutritionTalk #PatientCare #MedicalEducation

In this episode of The Feldman Protocol, a provocative question anchors the conversation: how much of cardiovascular risk is about cholesterol itself versus the context it operates in? Guest **Josh Wageman, DPT, PA-C, PhD**—a clinical lipid specialist and researcher—makes the case for using metaphor, metabolic health, and imaging to think differently about risk. The discussion spans coronary calcium scoring, lipid particles, insulin and inflammation, endurance training extremes, neurodegeneration, and why communicating science clearly actually matters. 🔥 This episode is sponsored by us -- Own Your Labs `http://ownyourlabs.com` -- private blood testing services.🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters3:00 – Why metaphors matter in medicine9:32 – Josh’s unconventional training path15:48 – Overtraining, illness, and collapse21:56 – Thyroid failure and recovery28:10 – Learning endocrinology the hard way34:42 – From PT to lipid specialist41:05 – Why lipids became the focus47:22 – Humor as a teaching tool53:40 – Writing the “lipid neighborhood”1:00:02 – Four pillars of metabolic health1:06:18 – Insulin and context over numbers1:12:35 – Inflammation isn’t one thing1:18:52 – Drugs as a risk factor1:25:14 – Cholesterol doesn’t live on paper1:31:28 – CAC as a reality check1:37:44 – Zero CAC and residual risk1:43:59 – Genetics vs lifestyle1:50:12 – ApoB’s necessary role1:56:27 – Why plaque still forms2:02:41 – Extreme endurance and CAC2:08:55 – When fitness backfires2:15:10 – Imaging vs biomarkers2:21:26 – Dementia and lipid biology2:27:40 – Neurodegeneration as frontier2:33:55 – Teaching clinicians differently2:40:08 – Credentials vs trust2:46:22 – Patient-first frameworks2:52:36 – Science communication failures2:58:49 – Measuring what matters3:04:55 – Meaning beyond metrics3:11:10 – Legacy and patient impact3:15:42 – Where Josh wants research to go3:18:43 – Closing thoughts and gratitude#FeldmanProtocol #DaveFeldman #JoshWageman #Lipids #Cholesterol #MetabolicHealth #ApoB #CACScore #Endocrinology #PreventiveCardiology #HealthCommunication

In this episode of The Feldman Protocol, Dave asks: what happens when a fertility specialist-turned-health thinker questions nutrition narrative? Guest Robert Kiltz, MD, makes the case for animal-based diets, metabolic flexibility, mindset, faith and medicine, clinical experience vs. guidelines, and the role of community. The conversation ranges from physiology and lipid metabolism to entrepreneurship, skepticism, and personal practice — always with an eye toward evidence and open inquiry.🔥 This episode is sponsored by us -- Own Your Labs http://ownyourlabs.com -- private blood testing services.🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:00 – Opening themes & big questions6:38 – Robert’s clinical background10:17 – Nutrition beliefs under the microscope13:55 – Defining metabolic health17:34 – Mindset, faith, and medicine21:12 – Carnivore experiences & context24:51 – LDL, risk, and interpretation28:29 – Citizen science in practice32:08 – Physiology vs. guidelines35:46 – The liver’s central role39:25 – Energy substrates explored43:03 – Food, behavior, and culture46:42 – Clinical anecdotes & caution50:20 – Lipids and metabolism debate53:59 – Diet, hormones, and stress57:37 – Weight, appetite, & satiety1:01:16 – Exercise, fitness, longevity1:04:54 – Medical orthodoxy pressures1:08:33 – Risk-benefit & uncertainty1:12:11 – Lab markers & context1:15:50 – Entrepreneurship & medicine1:19:28 – Patient communication style1:23:07 – Spirituality & health lens1:26:45 – Preventive care realities1:30:24 – Evidence vs. experience1:34:02 – Personal responsibility1:37:41 – Critics & open inquiry1:41:19 – Careers, courage, & change1:44:58 – Community & service1:48:36 – Learning from disagreement1:52:15 – Practical takeaways1:55:53 – Health as a journey1:59:32 – Gratitude & perspective2:03:10 – Final reflections2:06:49 – Closing thoughts & thanks#FeldmanProtocol #DaveFeldman #RobertKiltz #podcast #nutrition #healthjourney #openinquiry #metabolism #lowcarbcommunity #wellnessdiscussion #citizenscience #medicalethics #mindsetmatters #healthydebate #scienceconversation

In this episode of The Feldman Protocol, Dave asks a blunt question: is modern medicine structurally aligned against prevention? Guest **Emily Kaplan**, investigative science journalist and co-founder of the Broken Science Initiative, makes the case that incentives, not evidence, increasingly shape medical practice. They discuss conflicts of interest in research, the reproducibility crisis, metabolic health and lifestyle medicine, GLP-1 drugs, nutrition education gaps, and why outcomes often matter less than headlines.🔥 This episode is sponsored by us -- Own Your Labs `http://ownyourlabs.com` -- private blood testing services.🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters3:01 – Broken Science explained6:02 – Lifestyle vs polypharmacy9:03 – Medical school nutrition gaps12:13 – Incentives in healthcare15:57 – Sugar and cancer framing18:36 – Trial endpoints questioned21:11 – GLP-1s and tradeoffs24:01 – Weight loss vs health26:21 – Personal choice in diet29:02 – Early insulin signals32:25 – Publishing and paywalls35:10 – Journalism vs academia38:42 – Conflicts of interest42:08 – Peer review problems45:44 – Delays in publication49:12 – Who funds research52:48 – Education as prevention56:19 – Reproducibility crisis59:01 – Replication failures1:02:28 – Meta-analysis limits1:05:30 – Industry influence1:08:54 – What gets taught1:12:40 – Transparency gaps1:16:33 – Accountability in science1:38:20 – Where reform starts1:40:14 – Transparency vs incentives1:52:38 – Publishing power dynamics2:05:11 – Peer review bottlenecks2:17:44 – Conflicts without disclosure2:30:06 – Career risk in dissent2:42:31 – Nutrition sidelined again2:54:57 – Prevention vs treatment3:00:14 – N-of-1 data debate3:12:48 – Prospective study limits3:25:22 – Community-driven research3:37:49 – IRB and self-selection3:50:17 – Data ownership questions4:02:41 – Tech platforms for science4:10:06 – Scaling transparency4:15:32 – Reforming research norms4:18:54 – Public accountability4:20:41 – Communicating uncertainty4:22:53 – Where to find Emily4:23:05 – Final reflections#FeldmanProtocol #DaveFeldman #EmilyKaplan #BrokenScience #MedicalResearch #ScienceJournalism #MetabolicHealth #NutritionEducation #HealthcareIncentives #ReproducibilityCrisis #PreventiveMedicine #PublicHealth

Dr. Stephen Hussey, a functional medicine practitioner and type 1 diabetes survivor, shares his journey through a major heart attack despite normal risk markers. He discusses the significance of LDL cholesterol, hydration, and the complexities of plaque versus actual heart disease. The conversation dives into lifestyle impacts on health, the function of structured water, and the importance of blood flow dynamics. Stephen emphasizes the need for a personalized approach to heart health, advocating for self-directed recovery and critical thinking about conventional medical advice.

In this episode of The Feldman Protocol, we ask: What happens when clinical guidelines collides with messy real-world outcomes? Guest Bret Scher, MD, makes the case for rethinking metabolic health, evidence hierarchies, clinical incentives, LDL interpretation, ketogenic therapies, guideline rigidity, psychiatric applications of metabolic interventions, and his own evolution from cardiologist to medical director in the metabolic-health space.🔥 This episode is sponsored by us -- Own Your Labs http://ownyourlabs.com -- private blood testing services.🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:00 – How clinicians lose objectivity13:57 – When lifestyle advice keeps failing24:55 – The social cost of challenging LDL norms35:52 – Epidemiology’s limits in nutrition46:50 – Why “healthy user bias” distorts data57:47 – The Diet Doctor era and its impact1:08:45 – Red meat, risk, and uncertain evidence1:19:42 – Predicting outcomes vs. assuming causality1:30:40 – The guidelines problem inside medicine1:41:37 – Why patients succeed outside the system1:52:35 – Multiple dietary paths, not one dogma2:03:32 – How personality shapes dietary fit2:14:30 – From keto diet to medical therapy2:25:27 – The mindset shift toward low carb2:36:25 – How podcasting changed Bret’s trajectory2:47:22 – The origin story of Metabolic Mind2:58:20 – Metabolic psychiatry’s scientific emergence3:09:17 – Coalition for Metabolic Health vision#FeldmanProtocol #DaveFeldman #BretScher #MetabolicHealth #Keto #LowCarb #Cardiology #EvidenceBased #NutritionScience #LDL #Epidemiology #CriticalThinking #MetabolicPsychiatry #HealthPolicy #MedicalGuidelines #Wellness #MetabolicMind #Podcast #ScienceDiscussion

In this episode of The Feldman Protocol, what if a single overlooked nutrient could meaningfully alter how we think about chronic illness? Guest Dr. Darren Schmidt (DC, nutrition-focused clinician) makes the case for the role of B1 deficiency, discusses environmental toxic exposures, explores mitochondrial dysfunction, and examines lactic acidosis as a framework for understanding complex disease patterns. We also discuss metabolic pathways, autonomic issues, and how clinical observations can challenge conventional assumptions.🔥 This episode is sponsored by us -- Own Your Labs http://ownyourlabs.com -- private blood testing services.🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:00 – Early health shifts4:58 – First exposure incident6:56 – Discovering toxicity impacts8:54 – Mold and respiratory effects10:52 – Gas leak symptoms escalate12:50 – ER visit and missed signals14:48 – Autonomic dysfunction clues16:46 – Testing high-dose B118:44 – Rapid symptom relief20:42 – Mechanisms Dave examines22:40 – High-calorie malnutrition idea24:38 – Clinical responses to B126:36 – RCT possibilities28:34 – Origins of lactic acidosis theory30:32 – How toxins affect oxygen use32:30 – Capillary dilation mechanics34:28 – Mitochondrial parallels36:26 – Detox strategies overview38:24 – Dave’s metabolic framework40:22 – Pyruvate and lactate shifts42:20 – Rate limiters in metabolism44:18 – Nervous system involvement46:16 – Expanding symptom categories48:14 – Environmental drivers of illness50:12 – Mold detection and evidence52:10 – Radon and other exposures54:08 – Chronic illness complexity56:06 – Personal learning through crises58:04 – Rediscovering past medical history1:00:02 – Nutrient fortification lessons#FeldmanProtocol #DaveFeldman #DarrenSchmidt #metabolism #mitochondria #chronicillness #environmentalhealth #nutritionscience #lactate #thiamine #functionalhealth #biochemistry #healthpodcast #keto #lowcarb #detox #mitochondrialfunction

In this episode of The Feldman Protocol, can you truly build muscle and maintain health with just 15 minutes of exercise twice a week? Dave chats with Ben Bocchicchio, PhD in Exercise Physiology and Health, who makes the case for slow-motion resistance training as the ultimate efficiency hack. Guest explores mitochondrial optimization through high-intensity exercise, addresses middle-age workout mistakes, discusses low-carb nutrition strategies spanning five decades, and challenges conventional fitness wisdom with his revolutionary "safe emergency" training philosophy.🔵 This episode is sponsored by US -- Own Your Labs http://ownyourlabs.com -- private blood testing services.- 🩸Over 300 blood tests- 💰Extremely affordable- ❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support and keep advertisements limited, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:14 – Introduction and athletic background12:37 – Uncle Tony and Charles Atlas connection25:42 – Nautilus machines and slow training origins40:18 – Muscle fiber recruitment and intensity58:23 – Common middle-age exercise mistakes1:15:47 – Metabolic benefits of resistance training1:32:19 – Nutrition philosophy and 50-year approach1:50:33 – Food addiction and behavioral change2:08:56 – AI and personalized health predictions2:22:41 – Energy metabolism and final thoughts#FeldmanProtocol #DaveFeldman #BenBocchicchio #SlowTraining #ResistanceTraining #ExercisePhysiology #Mitochondria #LowCarb #Nutrition #MetabolicHealth #HighIntensityTraining #Fitness #Aging #Sarcopenia #HealthSpan #Longevity #BloodTesting #Science

In this episode of The Feldman Protocol, special guest Mike Mutzel explores groundbreaking research on the immune system, GLP-1, the gut microbiome and lean mass hyper-responders. They deep dive on the Lipid Energy Model, atherosclerosis mechanisms, immune system interactions, coronary artery imaging data, and conventional cardiovascular risk paradigms in metabolic health.🔥 This episode is sponsored by us -- Own Your Labs http://ownyourlabs.com -- private blood testing services.🩸Over 300 blood tests💰 Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldman Instagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters3:01 – Introduction and Mike's background9:14 – Medicine and nutrition evolution17:44 – Mindful eating and GLP-1 connections25:00 – Dave's cholesterol discovery story31:42 – Understanding lipid trafficking physics40:18 – Endothelial dysfunction and inflammation49:00 – LDL oxidation and modification theories58:23 – Atherosclerosis as immune response1:05:47 – Blood viscosity and cardiovascular risk1:15:19 – Self-censorship in scientific discourse1:25:33 – Continual exposure hypothesis debate1:32:19 – Own Your Labs citizen science project1:40:58 – Cholesterol paradox in aging populations1:50:33 – Metabolic health vs inflammation2:00:12 – Radiation concerns with CT angiograms2:08:56 – Triglycerides and ketogenic metabolism2:18:47 – Study results and mainstream response2:22:41 – Final thoughts and future research#FeldmanProtocol #DaveFeldman #DaveFeldmanGuest #LipidEnergyModel #LeanMassHyperResponder #LMHR #CholesterolResearch #MetabolicHealth #LDLCholesterol #CoronaryArteryImaging #ApoB #CardiovascularHealth #KetoResearch #CitizenScience #OwnYourLabs #LipidParticles #Atherosclerosis #EndothelialFunction #BloodViscosity #TriglyceridesTolerance #LPA

In this episode, Dave sits down with Austin, a metabolic data enthusiast and early adopter of continuous glucose monitoring (CGM) who brings a fascinating blend of self-experimentation, performance optimization, and deep curiosity about human physiology. From endurance training to dietary tracking, Austin shares his journey through the data-driven side of health — how he uses CGM, heart rate, and nutrient timing to reveal the body’s hidden patterns. Together, Dave and Austin explore how metrics can empower individuals to take ownership of their health, the tension between conventional guidelines and personal experimentation, and what the future of open-source health data could look like.🙏We only have one sponsor -- and it's us: https://OwnYourLabs.com🩸So keep getting your private blood testing through our platform and it will support the podcast. 🔗 CONNECT WITH DAVE FELDMAN PROTOCOLMain Channel: https://youtube.com/@realDaveFeldmanX/Twitter: https://x.com/realDaveFeldmanInstagram: https://instagram.com/realDaveFeldmanWebsite: https://thefeldmanprotocol.com⏱ Chapters 0:00 – Introduction & Setting the Stage5:45 – Opening Reflections on Austin’s Energy and Setting10:30 – Early Experiences That Sparked Curiosity15:15 – First Encounters with Data, Health, and Experimentation20:00 – The Origins of a Systems Approach to Nutrition25:00 – Breaking Down the Lipid Energy Model Concept30:15 – What Early Self-Experiments Revealed35:20 – Exploring LDL and APOB from a New Perspective40:10 – Why Traditional Cholesterol Framing Falls Short45:00 – Digging Into Lipoprotein Transport Mechanisms50:05 – Triglycerides, Remnants, and Particle Flow55:15 – When Energy Demand Shapes Lipid Behavior1:00:10 – The Lean Mass Hyper-Responder Pattern1:05:00 – Genetics, Metabolism, and Individual Variation1:10:30 – LPL and LDL Receptor Pathways in Context1:15:20 – Familial Hypercholesterolemia and Diverse Risk Profiles1:20:15 – How Population Data Can Mislead Individual Cases1:25:10 – Mendelian Randomization and Its Hidden Assumptions1:30:00 – Study Design: What We Miss When We Aggregate1:35:00 – The Duration vs. Magnitude of LDL Exposure1:40:10 – Interpreting Meta-Analyses with Caution1:45:15 – Revisiting the PESA Trial and Imaging Insights1:50:05 – Understanding the “Three-Line Graph” Debate1:55:00 – Statistical Power, Noise, and Over-Interpretation2:00:10 – Regression Models and Data-Slicing Pitfalls2:05:20 – Plaque Progression and Clinical Translation2:10:00 – PCSK9 Insights and Unexpected Outcomes2:15:00 – Beyond LDL: Inflammation and Contextual Risk2:20:05 – Revisiting the Bradford Hill Criteria for Causality2:25:10 – Consistency, Dose Response, and Biological Plausibility2:30:00 – The Changing Landscape of Trial Reporting2:35:05 – How 2004 Altered Medical Transparency Rules2:40:00 – Scientific Discourse, Debate, and Misinterpretation2:45:15 – The Role of Skepticism in Evidence Review2:50:10 – The Value of Epistemic Humility in Science2:55:00 – Open Data, Collaboration, and Collective Learning3:00:10 – Case Studies and Self-Experimentation Insights3:05:00 – Reflections on N=1 Studies and Public Data Sharing3:15:00 – Designing Smarter Studies for the Future3:20:05 – Lessons Learned from Real-World Observation3:25:00 – Future of Lipid Research and Citizen Science3:30:00 – Revisiting Key Misconceptions About Cholesterol3:35:10 – Bridging Gaps Between Clinicians and Researchers3:40:00 – Empowering Individuals Through Accessible Data3:50:00 – Community, Collaboration, and Scientific Openness3:55:10 – Final Thoughts on Evidence, Curiosity, and Persistence4:00:00 – Closing Reflections & Gratitude#FeldmanProtocol #LDL #HDL #Cholesterol #ASCVD #ContinuousGlucoseMonitoring #CGM #MetabolicHealth #DataDrivenHealth #CitizenScience #OwnYourLabs #QuantifiedSelf #HealthData #PerformanceOptimization #DaveFeldman #HumanPerformance #MetabolicFlexibility #OpenSourceScience