The Feldman Protocol

In Part 2 of this episode of The Feldman Protocol, Dave Feldman continues his conversation with Nick Norwitz, focusing on controversial topics that showcase Nick's scientific rigor. The discussion begins with Nick's methodical critique of Bryan Johnson's longevity claims, questioning his scientific methodology and the lack of transparency in his $2 million annual protocol. Nick explores the healthy user bias problem in red meat epidemiology, shares insights about choosing research over medical residency, discusses his famous Oreo vs. Statin experiment, and provides a detailed explanation of the carbohydrate-insulin model of obesity, demonstrating how it complements rather than contradicts thermodynamics while offering a more mechanistic understanding of weight regulation than traditional energy balance models. 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: YouTube.com/realDaveFeldman X/Twitter: x.com/realDaveFeldman Instagram: instagram.com/realDav…Website: thefeldmanprotocol.comEnergy Balance vs. Hormonal Models #NickNorwitz #BryanJohnson #Longevity #HealthInfluencer #ScientificRigor #RedMeat #HealthyUserBias #CarbohydrateInsulinModel #OreoVsStatin #InsulinResistance #MetabolicHealth #HealthResearch #PublicationBias #NutritionScience #EnergyBalance #HealthPodcast

In this episode of The Feldman Protocol, Dave Feldman sits down with Nick Norwitz, a PhD researcher focusing on metabolism who earned his doctorate from Oxford and graduated recently from Harvard Medical School. Nick shares his remarkable journey from elite distance runner at age 17 - capable of 2:45 marathons and 3,000-mile training years - to facing a cascade of health crises that would reshape his understanding of medicine. Nick recounts how his health deteriorated further with severe GI symptoms beginning at Dartmouth in 2017, eventually landing him in intensive care and palliative care with dangerously low weight levels. The discussion explores Nick's medical detective work, including his discovery of a cholesterol paradox: following a "heart-healthy" LDL-lowering diet that actually caused his LDL to jump from 95 to 321, while paradoxically improving his small dense LDL profile. Nick demonstrates scientific humility by acknowledging how his early lipid research perspectives have evolved, while discussing the institutional challenges he faces in publishing controversial research that might upset even his allies in the metabolic health field.🔗 CONNECT WITH DAVE FELDMAN PROTOCOL:Main Channel: @realDaveFeldmanX/Twitter: @realDaveFeldman Instagram: @realDaveFeldmanWebsite: thefeldmanprotocol.com⏰ CHAPTERS:1:16 - Introduction: Nick Norwitz, PhD Researcher & Harvard Medical Student1:43 - Life Mission: Making Metabolic Health Mainstream4:37 - Health Crisis Begins: GI Symptoms at Dartmouth (2017)5:11 - Athletic Background: Distance Running Success6:39 - Pattern of Fractures: From 90-Mile Weeks to Breaking Down7:24 - The Foot Fracture: X-Ray Misses, MRI Reveals Break8:26 - Osteoporosis Diagnosis: Bone Density of 70-80 Year Old14:51 - Fear and Urgency: The Deep Drive to Solve Health Problems26:37 - Life-Threatening Turn: Intensive Care & Palliative Care32:15 - The Cholesterol Paradox: Heart-Healthy Diet, LDL Jumps to 32132:50 - Early Lipid Analysis: Scientific Evolution and Humility34:00 - Medical Mystery: Low-Fat Diet Raises LDL36:06 - Research Partnership: Finding Collaborators55:53 - Controversial Research: Risk of Upsetting Allies1:06:53 - Publication Challenges: IRB Obstacles for Case Series1:07:28 - Meta-Analysis Struggles: Editor Ghosting on Positive Reviews#NickNorwitz #MetabolicHealth #HealthCrisis #Cholesterol #LDL #BoneDensity #GIHealth #HealthResearch #ScientificMethod #PersonalHealth #HealthPodcast

In Part 2 of this episode of The Feldman Protocol, Dave Feldman continues his conversation with renowned science journalist Gary Taubes, diving deeper into the institutional forces that perpetuate flawed nutritional science. This second part examines Gary's perspective on why paradigm shifts face such fierce resistance, exploring the career consequences researchers face when challenging established theories. The conversation addresses the famous "are we all idiots?" question from Gary's Pennington lecture, revealing how scientists inherit paradigms without questioning their foundations. Dave and Gary discuss the peer review process as both protector and barrier to innovation, the politics of academic publishing, and why researchers become emotionally invested in defending their work. Gary argues that the scientific establishment has abandoned true hypothesis testing in favor of confirmation bias, while exploring controversial topics like carnivore diets, GLP-1 drugs, and the sustainability myth. The discussion reveals how institutional pressures, career incentives, and cognitive biases create a system where scientists function more as advocates than investigators, potentially causing decades of harm through misguided dietary recommendations.🔗 CONNECT WITH DAVE FELDMAN:Main Channel: @realDaveFeldmanX/Twitter: x.com/realDaveFeldman Instagram: instagram.com/realDaveFeldman#GaryTaubes #ParadigmShift #PeerReview #ScientificMethod #Publication #CareerStakes #Carnivore #GLP1 #Diabetes #InsulinResistance #HealthPodcast #MetabolicScience

In Part 1 of this episode of The Feldman Protocol, Dave Feldman sits down with renowned science journalist Gary Taubes, author of groundbreaking books including "Good Calories, Bad Calories" and "The Case Against Sugar." This first part explores Gary's four-decade journey from physics journalism to becoming one of the most influential critics of nutritional research. The conversation delves deep into the philosophy of science itself, examining why he believes nutrition research has failed so spectacularly. Gary shares his evolution from covering physics breakthroughs at CERN to exposing the fundamental flaws in epidemiological studies that have shaped dietary guidelines for generations. Dave and Gary discuss the challenges of falsifiability in nutrition science, the dangers of emotional investment in hypotheses, and why the field attracts researchers more interested in confirmation than discovery. Gary provides a case for scientific skepticism, and how institutional biases, funding pressures, and cognitive blind spots have led to decades of misguided public health advice that may have caused more harm than good.🔗 CONNECT WITH DAVE FELDMAN:Main Channel: @realDaveFeldmanX/Twitter: @realDaveFeldman Instagram: @realDaveFeldman#GaryTaubes #NutritionScience #ScientificMethod #BadScience #Journalism #Epidemiology #LowCarb #Ketogenic #Obesity #Diabetes #HealthPodcast #MetabolicHealth

Cynthia Thurlow, a nurse practitioner and intermittent fasting expert, dives into the complexities of women's health and nutrition. She discusses the controversies surrounding intermittent fasting and highlights the importance of flexibility in dietary approaches. Cynthia shares insights on personal experimentation with different diets, tackling eating disorders, and the unique health needs of women, especially during menopause. Listeners can also learn about the role of seed oils, cholesterol, and the significance of vulnerability in health discussions.