The Incubator

Send us a textNeurodevelopmental disorders in children born to mothers involved in maternal motor vehicle crashes.Chang YH, Chien YW, Chang CH, Chen PL, Lu TH, Yen CF, Chiou HY, Tsai KS, Li CY.Pediatr Res. 2024 Sep 30. doi: 10.1038/s41390-024-03608-3. Online ahead of print.PMID: 39349820Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Join Matt Rysavy, director at UT Health Houston, and Courtney Vier, mother of three, as they share invaluable insights into caring for extremely preterm infants. They discuss the Tiny Baby Collaborative's mission to optimize care through research and shared protocols. Courtney opens up about her personal journey with premature sons, illustrating the emotional and practical challenges families face. The conversation emphasizes the importance of evidence-based practices and the critical role of collaboration between healthcare professionals and families.

Send us a textIn this episode, Dr. Guilherme Sant’Anna, a professor of pediatrics at McGill University, shares his journey in neonatology and his work in Brazil and Canada. He discusses the challenges and rewards of working in neonatal care and the differences between the healthcare systems in Brazil and Canada. Dr. Sant’Anna  also talks about the impact of the Neonatologia Brasil Facebook group, which he created to facilitate knowledge exchange among healthcare professionals in Brazil. He highlights the development of an educational website and the adoption of the 10 basic steps for neonatal care and perinatal asphyxia by the Brazilian government. Dr. Guilherme Sant'Anna emphasizes the importance of visiting units and seeing the reality on the ground to identify areas for improvement. He also discusses the concept of a Smart NICU, which aims to simplify monitoring and improve the interaction between babies, families, and healthcare professionals. In closing, Dr. Sant’Anna  offers advice for those wanting to make a difference, emphasizing the importance of sharing knowledge and approaching change with optimism and respect.Resources mentioned in episode:Neonatologia Brazil facebook group https://www.facebook.com/groups/neonatologiabrasil/?locale=pt_BR&_rdrContact:   guilherme.santanna@mcgill.caEpisode Webpage Link: https://www.the-incubator.org/post/246-from-brazil-to-canada-how-community-and-collaboration-can-lead-to-change-ft-dr-guilherSupport the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this episode of The Incubator Podcast Journal Club, Ben and Daphna explore a range of insightful articles that challenge current neonatal care practices. They begin by introducing an exciting new series called "From the Heart," focusing on cardiac journal reviews. Special guests from the EBNEO team join the discussion to dive into a recent trial on oxygen use in delivery room resuscitations for preterm infants. The hosts also examine a trial that investigates the impact of lung recruitment maneuvers before surfactant administration in extremely preterm neonates, exploring whether these techniques could reduce the need for mechanical ventilation.This episode provides in-depth analysis and a balanced discussion about the implications of these findings for everyday neonatal care. With guest appearances from Dr. Abdul Razak and Dr. Kiran Srivastava, the team also debates the latest meta-analysis on initial oxygen concentrations during neonatal resuscitation, offering fresh perspectives on potential changes in clinical practice. Whether you're interested in innovative resuscitation techniques or curious about how recent studies may shape the future of neonatal care, this episode offers thought-provoking insights that every NICU professional should hear. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this insightful discussion, Abdul Razak, a neonatal expert from Monash Children's Hospital, dives into critical findings on resuscitating preterm infants. He highlights a meta-analysis suggesting that higher initial oxygen concentrations can significantly reduce in-hospital mortality rates. The conversation touches on innovative data-sharing techniques in neonatal research and the vital need for tailored oxygen protocols. Razak also critiques existing studies, revealing how small changes in oxygen levels can dramatically impact outcomes for the most vulnerable infants.

Send us a textAntenatal magnesium sulphate reduces cerebral palsy after preterm birth, implementation into clinical practice needs to be accelerated globally to benefit preterm babies.Luyt K.Cochrane Database Syst Rev. 2024 Sep 24;9:ED000168. doi: 10.1002/14651858.ED000168.PMID: 39315530 No abstract available.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textLung recruitment before surfactant administration in extremely preterm neonates with respiratory distress syndrome (IN-REC-SUR-E): a randomised, unblinded, controlled trial.Vento G, Ventura ML, Pastorino R, van Kaam AH, Carnielli V, Cools F, Dani C, Mosca F, Polglase G, Tagliabue P, Boni L, Cota F, Tana M, Tirone C, Aurilia C, Lio A, Costa S, D'Andrea V, Lucente M, Nigro G, Giordano L, Roma V, Villani PE, Fusco FP, Fasolato V, Colnaghi MR, Matassa PG, Vendettuoli V, Poggi C, Del Vecchio A, Petrillo F, Betta P, Mattia C, Garani G, Solinas A, Gitto E, Salvo V, Gargano G, Balestri E, Sandri F, Mescoli G, Martinelli S, Ilardi L, Ciarmoli E, Di Fabio S, Maranella E, Grassia C, Ausanio G, Rossi V, Motta A, Tina LG, Maiolo K, Nobile S, Messner H, Staffler A, Ferrero F, Stasi I, Pieragostini L, Mondello I, Haass C, Consigli C, Vedovato S, Grison A, Maffei G, Presta G, Perniola R, Vitaliti M, Re MP, De Curtis M, Cardilli V, Lago P, Tormena F, Orfeo L, Gizzi C, Massenzi L, Gazzolo D, Strozzi MCM, Bottino R, Pontiggia F, Berardi A, Guidotti I, Cacace C, Meli V, Quartulli L, Scorrano A, Casati A, Grappone L, Pillow JJ.Lancet Respir Med. 2021 Feb;9(2):159-166. doi: 10.1016/S2213-2600(20)30179-X. Epub 2020 Jul 17.PMID: 32687801 Clinical Trial. Lung Recruitment Before Surfactant Administration in Extremely Preterm Neonates: 2-Year Follow-Up of a Randomized Clinical Trial.Gallini F, De Rose DU, Iuliano R, Romeo DM, Tana M, Paladini A, Fusco FP, Nobile S, Cota F, Tirone C, Aurilia C, Lio A, Esposito A, Costa S, D'Andrea V, Ventura ML, Carnielli V, Dani C, Mosca F, Fumagalli M, Scarpelli G, Giordano L, Fasolato V, Petrillo F, Betta P, Solinas A, Gitto E, Gargano G, Mescoli G, Martinelli S, Di Fabio S, Bernardo I, Tina LG, Staffler A, Stasi I, Mondello I, Scapillati E, Vedovato S, Maffei G, Bove A, Vitaliti M, Terrin G, Lago P, Gizzi C, Strozzi C, Villani PE, Berardi A, Cacace C, Bracaglia G, Pascucci E, Cools F, Pillow JJ, Polglase G, Pastorino R, van Kaam AH, Mercuri E, Orfeo L, Vento G; IN-REC-SUR-E Study Group; Malguzzi S, Rigotti C, Cecchi A, Nigro G, Costabile CD, Roma E, Sindico P, Venafra R, Mattia C, Conversano M, Ballardini E, Manganaro A, Balestri E, Gallo C, Catenazzi P, Astori MG, Maranella E, Grassia C, Maiolo K, Castellano D, Massenzi L, Chiodin E, Gallina MR, Consigli C, Sorrentino E, Bonato S, Mancini M, Perniola R, Giannuzzo S, Tranchina E, Cardilli V, Dito L, Regoli D, Tormena F, Battajon N, Arena R, Allais B, Guidotti I, Roversi F, Meli V, Tulino V, Casati A.JAMA Netw Open. 2024 Sep 3;7(9):e2435347. doi: 10.1001/jamanetworkopen.2024.35347.PMID: 39320892 Free PMC article. Clinical Trial.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Explore the critical role of blood culture volumes in diagnosing neonatal sepsis. The discussion dives into a recent study that emphasizes the significance of proper sample sizes and collection timing. Key findings reveal how adherence to guidelines can impact diagnostic accuracy. Tune in for insights on quality improvement in this vital area of infant healthcare!

Dive into the fascinating world of artificial intelligence as it tackles infant healthcare! Discover how a groundbreaking machine learning algorithm is being validated to identify infants at risk of Hypoxic Ischemic Encephalopathy (HIE). The discussion covers the study's innovative methodology and impressive performance metrics. Understand the potential real-world implications of these findings in clinical practice. This episode sheds light on the intersection of technology and medicine, promising to revolutionize infant care!

Send us a textIn this episode of Tech Tuesday on The Incubator Podcast, hosted by Daphna, Mark O'Sullivan, PhD, CEO, and co-founder of NeuroBell, discusses their cutting-edge medical device aimed at improving neonatal seizure detection. NeuroBell, a spinoff from the Infant Research Center at University College Cork, has developed a pocket-sized, wireless EEG monitor equipped with AI-based seizure detection for newborns. This device is designed to be user-friendly for bedside staff and eliminates the need for extensive EEG training, making it accessible in hospitals with limited EEG resources.Mark shares the story behind the development of the device, highlighting the challenges of acquiring EEG data due to its small signal and the importance of minimizing seizure burden in newborns. He explains how the device addresses gaps in care by providing real-time seizure detection in settings where traditional EEG monitoring might not be readily available.Currently in clinical trials in Ireland and the U.S., NeuroBell aims to provide a streamlined solution that could be particularly useful in community hospitals and smaller settings. The episode wraps up with Mark's vision for the future of NeuroBell, which includes FDA submission and market release in 2025. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!