The Incubator

Send us a textAntenatal magnesium sulphate reduces cerebral palsy after preterm birth, implementation into clinical practice needs to be accelerated globally to benefit preterm babies.Luyt K.Cochrane Database Syst Rev. 2024 Sep 24;9:ED000168. doi: 10.1002/14651858.ED000168.PMID: 39315530 No abstract available.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textLung recruitment before surfactant administration in extremely preterm neonates with respiratory distress syndrome (IN-REC-SUR-E): a randomised, unblinded, controlled trial.Vento G, Ventura ML, Pastorino R, van Kaam AH, Carnielli V, Cools F, Dani C, Mosca F, Polglase G, Tagliabue P, Boni L, Cota F, Tana M, Tirone C, Aurilia C, Lio A, Costa S, D'Andrea V, Lucente M, Nigro G, Giordano L, Roma V, Villani PE, Fusco FP, Fasolato V, Colnaghi MR, Matassa PG, Vendettuoli V, Poggi C, Del Vecchio A, Petrillo F, Betta P, Mattia C, Garani G, Solinas A, Gitto E, Salvo V, Gargano G, Balestri E, Sandri F, Mescoli G, Martinelli S, Ilardi L, Ciarmoli E, Di Fabio S, Maranella E, Grassia C, Ausanio G, Rossi V, Motta A, Tina LG, Maiolo K, Nobile S, Messner H, Staffler A, Ferrero F, Stasi I, Pieragostini L, Mondello I, Haass C, Consigli C, Vedovato S, Grison A, Maffei G, Presta G, Perniola R, Vitaliti M, Re MP, De Curtis M, Cardilli V, Lago P, Tormena F, Orfeo L, Gizzi C, Massenzi L, Gazzolo D, Strozzi MCM, Bottino R, Pontiggia F, Berardi A, Guidotti I, Cacace C, Meli V, Quartulli L, Scorrano A, Casati A, Grappone L, Pillow JJ.Lancet Respir Med. 2021 Feb;9(2):159-166. doi: 10.1016/S2213-2600(20)30179-X. Epub 2020 Jul 17.PMID: 32687801 Clinical Trial. Lung Recruitment Before Surfactant Administration in Extremely Preterm Neonates: 2-Year Follow-Up of a Randomized Clinical Trial.Gallini F, De Rose DU, Iuliano R, Romeo DM, Tana M, Paladini A, Fusco FP, Nobile S, Cota F, Tirone C, Aurilia C, Lio A, Esposito A, Costa S, D'Andrea V, Ventura ML, Carnielli V, Dani C, Mosca F, Fumagalli M, Scarpelli G, Giordano L, Fasolato V, Petrillo F, Betta P, Solinas A, Gitto E, Gargano G, Mescoli G, Martinelli S, Di Fabio S, Bernardo I, Tina LG, Staffler A, Stasi I, Mondello I, Scapillati E, Vedovato S, Maffei G, Bove A, Vitaliti M, Terrin G, Lago P, Gizzi C, Strozzi C, Villani PE, Berardi A, Cacace C, Bracaglia G, Pascucci E, Cools F, Pillow JJ, Polglase G, Pastorino R, van Kaam AH, Mercuri E, Orfeo L, Vento G; IN-REC-SUR-E Study Group; Malguzzi S, Rigotti C, Cecchi A, Nigro G, Costabile CD, Roma E, Sindico P, Venafra R, Mattia C, Conversano M, Ballardini E, Manganaro A, Balestri E, Gallo C, Catenazzi P, Astori MG, Maranella E, Grassia C, Maiolo K, Castellano D, Massenzi L, Chiodin E, Gallina MR, Consigli C, Sorrentino E, Bonato S, Mancini M, Perniola R, Giannuzzo S, Tranchina E, Cardilli V, Dito L, Regoli D, Tormena F, Battajon N, Arena R, Allais B, Guidotti I, Roversi F, Meli V, Tulino V, Casati A.JAMA Netw Open. 2024 Sep 3;7(9):e2435347. doi: 10.1001/jamanetworkopen.2024.35347.PMID: 39320892 Free PMC article. Clinical Trial.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this episode of Tech Tuesday on The Incubator Podcast, hosted by Daphna, Mark O'Sullivan, PhD, CEO, and co-founder of NeuroBell, discusses their cutting-edge medical device aimed at improving neonatal seizure detection. NeuroBell, a spinoff from the Infant Research Center at University College Cork, has developed a pocket-sized, wireless EEG monitor equipped with AI-based seizure detection for newborns. This device is designed to be user-friendly for bedside staff and eliminates the need for extensive EEG training, making it accessible in hospitals with limited EEG resources.Mark shares the story behind the development of the device, highlighting the challenges of acquiring EEG data due to its small signal and the importance of minimizing seizure burden in newborns. He explains how the device addresses gaps in care by providing real-time seizure detection in settings where traditional EEG monitoring might not be readily available.Currently in clinical trials in Ireland and the U.S., NeuroBell aims to provide a streamlined solution that could be particularly useful in community hospitals and smaller settings. The episode wraps up with Mark's vision for the future of NeuroBell, which includes FDA submission and market release in 2025. As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Dr. Suresh Gautham, Chair of Pediatrics at Nemours Children's Hospital, draws fascinating links between neonatology and detective work in his talk. Meanwhile, Dr. Terrie Inder discusses innovative strategies to enhance neurological outcomes in NICU graduates. Pediatric nephrologist Chryso Pefkaros Katsoufis reveals groundbreaking research on neonatal biomarkers of chronic kidney disease. Finally, Dr. Lauren Ruoss showcases the transformative role of point-of-care ultrasound in neonatal care. These insights highlight the future of pediatric medicine and its exciting advancements.

Send us a textIn this special episode of The Incubator podcast, Ben and Daphna wrap up the 2024 Delphi Neonatal Innovation Conference, sharing their favorite moments and highlights. This episode features the exclusive audio from four captivating Delphi talks. Dr. Suresh Gautham, Chair of Pediatrics at Nemours Children's Hospital, opens with an intriguing talk on "What Neonatologists Can Learn from Sherlock Holmes," drawing parallels between neonatal practice and detective work. Dr. Terrie Inder from CHOC delivers insights in "The Science and Art of Improving Neurological Outcomes in NICU Graduates," blending research with practical care strategies. Pediatric nephrologist Chryso Pefkaros Katsoufis from the University of Miami explores "The Road Less Traveled? Neonatal Biomarkers of Chronic Kidney Disease," shedding light on innovative approaches to CKD in newborns. Finally, Dr. Lauren Ruoss, from Winnie Palmer Hospital, enchants the audience with "Abracadabra! Making POCUS Appear in the NICU," detailing the role of point-of-care ultrasound in neonatal care. Ben and Daphna conclude the episode by previewing exciting upcoming developments for The Incubator network. Don’t miss this unique opportunity to hear from some of the leading voices in neonatal care.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this special episode of The Incubator podcast, Ben and Daphna wrap up the 2024 Delphi Neonatal Innovation Conference, sharing their favorite moments and highlights. This episode features the exclusive audio from four captivating Delphi talks. Dr. Suresh Gautham, Chair of Pediatrics at Nemours Children's Hospital, opens with an intriguing talk on "What Neonatologists Can Learn from Sherlock Holmes," drawing parallels between neonatal practice and detective work. Dr. Terrie Inder from CHOC delivers insights in "The Science and Art of Improving Neurological Outcomes in NICU Graduates," blending research with practical care strategies. Pediatric nephrologist Chryso Pefkaros Katsoufis from the University of Miami explores "The Road Less Traveled? Neonatal Biomarkers of Chronic Kidney Disease," shedding light on innovative approaches to CKD in newborns. Finally, Dr. Lauren Ruoss, from Winnie Palmer Hospital, enchants the audience with "Abracadabra! Making POCUS Appear in the NICU," detailing the role of point-of-care ultrasound in neonatal care. Ben and Daphna conclude the episode by previewing exciting upcoming developments for The Incubator network. Don’t miss this unique opportunity to hear from some of the leading voices in neonatal care.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this special episode of The Incubator podcast, Ben and Daphna wrap up the 2024 Delphi Neonatal Innovation Conference, sharing their favorite moments and highlights. This episode features the exclusive audio from four captivating Delphi talks. Dr. Suresh Gautham, Chair of Pediatrics at Nemours Children's Hospital, opens with an intriguing talk on "What Neonatologists Can Learn from Sherlock Holmes," drawing parallels between neonatal practice and detective work. Dr. Terrie Inder from CHOC delivers insights in "The Science and Art of Improving Neurological Outcomes in NICU Graduates," blending research with practical care strategies. Pediatric nephrologist Chryso Pefkaros Katsoufis from the University of Miami explores "The Road Less Traveled? Neonatal Biomarkers of Chronic Kidney Disease," shedding light on innovative approaches to CKD in newborns. Finally, Dr. Lauren Ruoss, from Winnie Palmer Hospital, enchants the audience with "Abracadabra! Making POCUS Appear in the NICU," detailing the role of point-of-care ultrasound in neonatal care. Ben and Daphna conclude the episode by previewing exciting upcoming developments for The Incubator network. Don’t miss this unique opportunity to hear from some of the leading voices in neonatal care.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this special episode of The Incubator podcast, Ben and Daphna wrap up the 2024 Delphi Neonatal Innovation Conference, sharing their favorite moments and highlights. This episode features the exclusive audio from four captivating Delphi talks. Dr. Suresh Gautham, Chair of Pediatrics at Nemours Children's Hospital, opens with an intriguing talk on "What Neonatologists Can Learn from Sherlock Holmes," drawing parallels between neonatal practice and detective work. Dr. Terrie Inder from CHOC delivers insights in "The Science and Art of Improving Neurological Outcomes in NICU Graduates," blending research with practical care strategies. Pediatric nephrologist Chryso Pefkaros Katsoufis from the University of Miami explores "The Road Less Traveled? Neonatal Biomarkers of Chronic Kidney Disease," shedding light on innovative approaches to CKD in newborns. Finally, Dr. Lauren Ruoss, from Winnie Palmer Hospital, enchants the audience with "Abracadabra! Making POCUS Appear in the NICU," detailing the role of point-of-care ultrasound in neonatal care. Ben and Daphna conclude the episode by previewing exciting upcoming developments for The Incubator network. Don’t miss this unique opportunity to hear from some of the leading voices in neonatal care.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textAnnick Duvivier shares her experience in the NICU with her preemie daughter, Thalia, and her journey with pumping and breastfeeding. She discusses the challenges she faced, including the emotional toll of being separated from her baby, the difficulty of pumping and producing milk, and the loneliness she felt. Annick also talks about the importance of kangaroo care and the positive impact it had on both her and her daughter. Despite the hardships, Annick's resilience and determination shine through as she navigates the NICU journey. Annick shares her experience of being in the NICU and the challenges she faced as a parent. She talks about the strict schedule of kangaroo care and feeding, and the difficulties of coordinating pumping and breastfeeding. Annick also discusses the emotional toll of not being able to hold her baby for long periods of time and the isolation she felt without any visitors. She found solace in art and used painting as a form of self-care during her time in the NICU. Annick's painting, which depicts her pumping milk with stickers from the NICU in the background, is a powerful representation of her journey. Despite the initial concerns and risks, Annick's daughter, Thalia, is now a thriving three-year-old with no health issues. Annick encourages other NICU parents to be patient, prioritize breast milk, and seek support from available resources.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this episode of the Incubator: At the bench, we talk with, Dr. Augusto Zani, a pediatric surgeon scientist who discusses his work on fetal lung regeneration and the use of stem cell derivatives and extracellular vesicles for diagnostics and therapy. He shares his journey from surgical training to becoming a surgeon scientist and the challenges he faced along the way. Dr. Zani also explains his transition from studying necrotizing enterocolitis to congenital diaphragmatic hernia (CDH) and the unanswered questions in lung hypoplasia related to CDH. He highlights the importance of understanding the mechanisms behind these conditions and the potential of extracellular vesicles in promoting lung growth and regeneration. Dr. Augusto Zani discusses his research on congenital diaphragmatic hernia (CDH) and the potential use of extracellular vesicles (EVs) as a therapy. He also discusses the role of inflammation in CDH and how EVs have both regenerative and anti-inflammatory properties. Dr. Zani also mentions the potential use of EVs in other pediatric surgical conditions, such as gastroschisis and spina bifida. He concludes by sharing his excitement about moving his lab to St. Louis Children's Hospital in the U.S.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!