Chef José Andrés discusses his founding of World Central Kitchen, providing food relief in disaster areas and war zones. They explore the impact of his work, the chaos of restaurants preparing him for relief work, and the growth of his organization in terms of meals served and volunteers involved.

Laraaji, a musician known for his experimentation with instruments and collaboration with Brian Eno, talks with Marc about his lifelong experimentation with instruments, collaboration with Brian Eno, and his ongoing practice of laughter meditation. They also discuss his musical beginnings, the power of songs in bondage, manifesting and the power of language, the story behind his name change, the connection between laughter and meditation, and a discussion about the movie 'The Wolf of Wall Street'.

John Wilson, filmmaker, discusses his lifelong fascination with film and the creation of his show, How To with John Wilson. They explore the art of documentary filmmaking, the influence of street photographers, and the visual poetry of montage. Wilson reflects on his early exposure to art and photography, the process of creating authentic characters, and using humor as a coping mechanism. They also touch on the Titanic conspiracy theory, police work fabrications, and the battle between free speech and censorship in comedy.

Lou Adler, accomplished music industry career and producer of hit songs, albums, and films, talks about The Roxy's 50th anniversary, his early days in the music industry, the music scene in LA in the 1960s, directing films like 'Up in Smoke,' and working with talented songwriters. They also discuss famous comedians who performed at the Roxy and Comedy Store.

Dan Soder, a stand-up comedian known for The Bonfire and Billions, talks with Mark Maron about their past struggles in radio, losing loved ones, and finding solace in pro wrestling. They also explore the impact of people pleasing on their comedy careers and share personal anecdotes about family and early comedy experiences.

Former Nickelodeon star, Jennette McCurdy, shares her perspective after releasing a blockbuster memoir about her abusive upbringing and career. She discusses separating her Nickelodeon past from her self-actualized present and her new podcast, Hard Feelings, where she explores sensitive topics. Topics include dysfunctional mother-daughter relationships, body image struggles, managing weight with noom, the importance of empathy, struggles with eating disorders, the impact of the mother figure, the dark side of the entertainment industry, and the launch of her podcast and return of Cream Magazine.

Joan Baez, folk singer who embraced sad music, talks about the folk scene in Cambridge, her pacifism shaped activism, and rebuilding her relationship with her son. They also discuss the impact of a documentary about Baez, people wearing masks in public, making a film, music, drugs, and activism, trauma's impact on relationships, and a documentary and rock and roll magazine.

Comedians Doug Stanhope and Louis Katz join Marc to discuss their new projects and reflect on their early days in the comedy world. Topics include controversial children attending comedy shows, childhood memories of violence, dealing with difficult audiences, Jewish heritage and globalization, smoking among comedians in Austin, challenges of creating a period piece, perspectives on COVID-19 and freedom of speech, changing minds about racism, and the art of stand-up comedy and joke crafting.

Rob Halford, Judas Priest frontman, talks about his life, coming out story, the court case regarding Judas Priest's First Amendment battle, and the origins of heavy metal. They also discuss the challenges of expressing emotions, the power of music, and the evolving sexuality in hair metal bands.

Arnold Schwarzenegger and Marc Maron discuss their differing approaches to life's challenges, generational change, and being useful. They also talk about bodybuilding, James Cameron's vegan advice, and Arnold's rivalry-slash-friendship with Sylvester Stallone.