Raw Talk Podcast

There is no shortage of phrases related to time - and for good reason! Nearly all biological processes have evolved to follow a day-night cycle every 24 hours. In our fifty-second episode, Max and Richie talk all things circadian rhythm, and discuss how this phenomenon can also impact day-to-day things like wellbeing, illness and even jet-lag. To supplement their discussion, Richie sits down with U of T Professor and circadian expert, Dr. Martin Ralph, who sheds light on how these cycles are intimately-linked to just about every complex disease you can name, and provides some much-needed advice to keep our internal clocks synchronized. Although the exact mechanisms of circadian control are still a topic of active research (not to mention the highlight of the 2017 Nobel Prize in Medicine), this is an episode to stay awake for... unless it's past your bedtime. Until next time, keep it raw! Written by: Richie Jeremian

Open any newspaper and you'll stumble across an article on the opioid crisis. While some mention illicit fentanyl, other pieces talk about doctor-prescribed substances. What is actually going on? On this episode we'll be exploring the basics of this multi-faceted topic: how did this crisis start, and why? To answer this question, we spoke to a variety of stakeholders and did some sleuthing of our own. You'll be hearing from two clinician scientists, both experts in pain management and research: Drs. Andrea Furlan and Hance Clarke. Together, they provided us a historical perspective on the crisis, and its current transcendence beyond the prescription pad. Matt Johnson, a harm reduction coordinator at Queen West Community Health Centre, shared his frontline perspective on the crisis. Finally, we had the opportunity to talk to City Councillor Joe Mihevc, the Chair of the Toronto Board of Health, the body that recently called upon the federal government to decriminalize all drugs. As they are in society, the perspectives we gathered here are diverse, yet telling of the complexity of this issue. We wrapped up the show with ideas on what needs to happen next, and hopes for the future. Until next time, keep it raw! Written by: Alexandra Mogadam Dr. Andrea Furlan's profile Dr. Hance Clarke's profile City Councillor Joe Mihevc's website Toronto Harm Reduction Alliance Harm reduction at Queen West Community Health Centre Toronto Overdose Prevention Society's Go Fund Me page CAMH's fact sheet on street fentanyl Ontario's new Consumption and Treatment Services model Toronto Overdose Prevention Society's response to Ontario's new Consumption and Treatment Services model Globe and Mail article on Toronto Board of Health's call for decriminalization of all drugs    

Is it possible to move a wheelchair simply by thinking about it? Surprisingly, the answer is yes! Medical devices, such as brain-computer interfaces and insulin pumps, have dramatically changed the landscape of the medical field. They have enabled clinicians and patients to manage a range of diseases which were impossible to cope with or cure prior to the invention of these devices. Tune in to this week's episode as we sit down with Dr. David Urbach, Surgeon-in-Chief at the Women's College Hospital, to discuss the invention, regulation of, and controversy surrounding medical devices. We also spoke to two students - George Hanna, a Master of Applied Science and Engineering student at the Holland Bloorview Research Institute, and Amy Khan, an MD/PhD student at U of T - who are in the process of designing novel devices to help mobilize people with disabilities and make laparoscopic surgery safer, respectively. Lastly, we reached out to two patients - Doug Oliver (and his wife Diane), whose life was transformed by deep brain stimulation, as well as Lindsay Oliver, whose insulin pump is a fundamental part of her daily life. Thanks for tuning in, and until next time, keep it raw! Written by: Aditi Desai

The day has arrived. After being prohibited in Canada for over 90 years, cannabis has been legalized for recreational use across the country. Just about everybody has an opinion on cannabis legalization. Throughout this episode, you'll hear from people around downtown Toronto, sharing their views on legalization and some interesting personal experiences. There are also many misconceptions out there. We sat down with some researchers who study cannabis at the University of Toronto to learn about the science behind cannabis. The conversation starts with Lauren DeFreitas, a graduate student at CAMH whose research focuses on the THC and CBD content of different products and how these active chemical compounds in cannabis impact health outcomes. Dr. Ruth Ross is a professor in the Department of Pharmacology and Toxicology at the University of Toronto. She talks about how THC interacts with the endocannabinoid system at the molecular level, and the potential to target this complex system for therapeutic purposes. Karolina Kozak is a PhD candidate from Dr. Tony George's lab at CAMH. Her work focuses on cannabis use disorder in schizophrenia and she tells us about what exactly happens with the brain in addiction. We also delve into some of the societal impacts of cannabis legalization in this episode. We talked to Dr. Pat Erickson, a professor emerita at the Department of Sociology at the University of Toronto. Her work looked at some of the personal and societal impacts of criminalization. We'll hear from her about the normalization of cannabis use over time, and the importance of having engaging and accurate educational material, especially for youth, now that it has been legalized. Sudha Sabanadesan is a policy development officer at Toronto Public Health. She tells us about some of the concerns they have going forward, including cannabis use by adolescents and driving while impaired, and the public health perspective on harm reduction. There's a lot to learn about cannabis legalization and this episode is a great place to start! If you haven't already, let us know what you think of the show! It's an important way for us to create the content you want to hear. Please complete this survey (https://rawtalkpodcast.typeform.com/to/PH50b2?name=RawTalk&source=Shownotes) - it'll only take you 5 minutes! Written by: Thamiya Vasanthakumar

Inflammation, the gut, microbes, cortisol, and sore joints... what do these things have in common? Tune in to this week's episode as we explore what it's like living with an autoimmune condition. You'll hear the perspectives of four individuals - Vanessa, Bonnie, Yohanna, and Megan - as they reflect on their journeys to receiving their diagnoses. They share their thoughts on navigating the Canadian Healthcare System and give advice for those newly diagnosed. You'll also hear from Dr. Kenneth Croitoru - gastroenterologist at Mount Sinai Hospital and Professor in the Department of Immunology at U of T - as well as Dr. Jayne Danska - Senior Scientist at The Hospital for Sick Children and Professor in Medical Biophysics and Immunology at U of T - who breakdown autoimmunity, debunk some common myths associated with autoimmune diseases, and discuss some of their exciting work in identifying factors causing susceptibility to Crohn's and Type I Diabetes respectively. Until next time, #KeepItRaw! Written by: Aditi Desai University of Toronto Sports Medicine Clinic University Health Network Arthritis Program Juvenile Diabetes Research Foundation (JDRF) Danska Lab Article: Host lifestyle affects human microbiota on daily timescales Crohn's and Colitis Canada The GEM Project Croitoru Lab

One in four people will be affected by mental or neurological disorders at some point in their lives. This is particularly true among graduate students, who recent studies suggest, are at an increased risk for depression and anxiety. In this episode, you'll hear the voices of a group of graduate students across Toronto as they share their stories and struggles with mental illness. Alongside each story, you'll hear about the resources and coping strategies that allowed them to better manage their mental health. Check out our website for featured guest names and all the great resources they share in the episode! Written by: Melissa Galati and Vanessa Cservid Event: The Art of Mindfulness @ RYU Apparel Janine: Student Health & Wellness Centre Website Janine: "How are you feeling today?" Mental Health Resources Directory Jacalyn: Grad Minds Jacalyn: Elemental Magazine Jacalyn: Counselling at OISE Jacalyn: CBT workshops Anjali: Toronto Distress Centre Geith: Health & Wellness Appointment Booking Website Geith: UofT Gyms Geith: Fitness Classes Alena: Hard Feelings Counselling Lisa: Good2Talk Helpline Lisa: BetterHelp Jarrett: "I Don't Want to Talk About It": Overcoming the Secret Legacy of Male Depression (Book) Liam: Safetalk Training Conflict Resolution Centre Conflict Resolution Centre Workshops Denise: Mental Health Commision of Canada Website Denise: Mental Health First Aid Training Courses in Toronto Directory of Services for Graduate Students

We're back! Join Mel & Grace for a quick reflection of some season 2 highlights and a preview of the upcoming season 3 of Raw Talk. What's in store? We'll discuss emerging medical devices, the legalization of marijuana in Canada, indigenous health, and to start us off - graduate student mental health. These topics, plus many more as we dive into sharing the diverse stories and perspectives behind medical science issues and discoveries. See you in a couple of weeks... and until then, keep it raw! Written by: Grace Jacobs and Melissa Galati  

For our season finale, we pick up from last episode to bring you the second instalment of our Raw Talk Live event, a panel discussion focusing on new methods of science communication. Our panelists provide their unique perspectives on how we can (and why we should!) use new media and technologies to make science more accessible to the public. You'll hear from Dr. Vicky Forster, a Postdoc at SickKids Hospital and Science Communicator; Kevin Millar, Senior VP of Creative and Medical Science at INVIVO Communications; Elah Feder, Co-Host and Producer of the Undiscovered Podcast; Helen Kontozopoulos, Co-Founder and Co-Director of the Department of Computer Science Innovation Lab, University of Toronto; and our moderator, Eryn Tong, Raw Talk Podcaster and MSc Candidate. To reflect further on the rich discussion and insights from the panel, you'll hear from Richie and Eryn throughout this episode as well. We'll be back shortly for the debut of Season 3, but until then, keep it raw! Written by: Eryn Tong

August is flashback month, as we move back in time to present you recordings from the event we hosted back in May, Raw Talk Live. This week's instalment presents the first of two panel discussions, and explores public engagement in science. We hear from an array of speakers, diving into the personal and the political dimensions of this theme. Joining us is Dr. Mehrdad Hariri, CEO and Founder of the Canadian Science Policy Centre; Doina Oncel, the CEO and Founder of hEr VOLUTION; Dan Weaver, PhD Candidate at the Department of Physics, University of Toronto; Connie Putterman, a long-time parent advocate in the autism research world, and now a Masters candidate in the Translational Research Program, University of Toronto; and our moderator Tetyana Pekar, Founder and Academic Editor at Pekar Editing. Of course, you will also be hearing from your trusty hosts Jabir and Alex, as they reflect on the discussion, and the experience of organizing a live-podcasting event. Until next time, keep it raw! Written by: Alexandra Mogadam  

Did you know that nearly 500 million people globally suffer from some form of irreversible kidney-related disease? These individuals may wait years before receiving a transplant! In this installment of Raw Talk, Dr. Lisa Robinson, Paediatric Nephrologist and Senior Scientist at The Hospital for Sick Children chats with Melissa about the forefront of kidney disease research. James and Anton also pay a visit to Dr. Markus Selzner, transplant surgeon and collaborator of Dr. Robinson's, to learn about new breakthroughs in kidney transplantation. Moreover, as Chief Diversity Officer at the University of Toronto's Faculty of Medicine, Dr. Robinson discusses initiatives currently being implemented to tackle inequality at the University. James and Anton are then fortunate enough to sit down with Anita Balakrishna, Diversity Strategist at the Faculty of Medicine, and delve deeper into the proactive work being done to curb discrimination at different stages of the student experience. Until next time, keep it raw! Written by: James Saravanamuttu and Anton Rogachov