New Books in Science

Genome sequencing is one of the most exciting scientific breakthroughs of the past thirty years. But what precisely does it involve and how is it developing?In Genomics: How Genome Sequencing Will Change Healthcare (Random House, 2022), Rachael Pells explains the science behind genomics. She analyses its practical applications in medical diagnosis and the treatment of conditions that range from cancer to severe allergic reactions to cystic fibrosis. She considers its potential to help with advances in agriculture and environmental science. She explores the ethics of genetic modification and the dangers involved when humans 'play God'. And she addresses the fundamental question: to what extent will future advances transform human longevity and the quality of life.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

For many philosophers, the fact that scientists take different perspectives on the world is an obstacle to being a realist about the world. In Perspectival Realism (Oxford University Press, 2022), Michela Massimi argues that to the contrary the plurality of perspectives is the driving force behind realism. On her view, the scientific realism that emerges out of the perspectival nature of scientific representation takes perspectival models as inferential blueprints for exploring what is possible. The realist’s primitives are not essential properties, but the stable lawlike dependencies that are identified again and again from different perspectives. Massimi, who is professor of philosophy at the University of Edinburgh, also shows how scientific communities develop “natural kinds with a human face”: evolving groupings of modally robust phenomena that result from historically and culturally situated systems of scientific practices. Massimi’s book constructs a new vision of what scientific realism can be that will be highly influential for years to come.This book is available open access here. Carrie Figdor is professor of philosophy at the University of Iowa. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

The last few years have brought to the fore the brilliant work of scientists as they worked to find a vaccine for Covid-19. But have you ever stopped to think about the role of biological materials in this and other science- and health-related research?In this episode of SSEAC Stories, Dr Natali Pearson is joined by Associate Professor Sonja van Wichelen to take a close look at the complex world of global health governance, with a particular focus on biotechnology and bioscience governance in Indonesia. They discuss the crucial role of biological materials exchange for scientific research, what rules govern their use, and the history of inequality that has underpinned scientific use of biological materials. Taking Indonesia’s recent efforts to gain leverage in the uneven space of the global bioeconomy, they explore how bioscience governance mechanisms can perpetuate, or sometimes help address, global power inequalities in the way biological material is used.About Sonja van Wichelen:Sonja van Wichelen is Associate Professor with the School for Social and Political Sciences at the University of Sydney. She researches the social implications of biotechnology and law and has focused on reproductive technologies in previous projects. More recently she is examining bioscience governance in Southeast Asia. Focusing on Indonesia, she is particularly interested in the relationship between regulatory frameworks and global inequality. She is the author of Legitimating Life: Adoption in the Age of Globalization and Biotechnology (Rutgers University Press, 2019), and Religion, Gender, and Politics in Indonesia: Disputing the Muslim Body (Routledge, 2010).For more information or to browse additional resources, visit the Sydney Southeast Asia Centre’s website: www.sydney.edu.au/sseac. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

On July 4, 2012, the announcement came that one of the longest-running mysteries in physics had been solved: the Higgs boson, the missing piece in understanding why particles have mass, had finally been discovered. On the rostrum, surrounded by jostling physicists and media, was the particle's retiring namesake--the only person in history to have an existing single particle named for them. Why Peter Higgs? Drawing on years of conversations with Higgs and others, Close illuminates how an unprolific man became one of the world's most famous scientists. Close finds that scientific competition between people, institutions, and states played as much of a role in making Higgs famous as Higgs's work did.A revelatory study of both a scientist and his era, Elusive: How Peter Higgs Solved the Mystery of Mass (Basic Book, 2022) will remake our understanding of modern physics.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Imagine knowing years in advance whether you are likely to get cancer or having a personalized understanding of your individual genes, organs, and cells. Imagine being able to monitor your body's well-being, or have a diet tailored to your microbiome. The Secret Body reveals how these and other stunning breakthroughs and technologies are transforming our understanding of how the human body works, what it is capable of, how to protect it from disease, and how we might manipulate it in the future.Taking readers to the cutting edge of research, Daniel Davis shows how radical new possibilities are becoming realities thanks to the visionary efforts of scientists who are revealing the invisible and secret universe within each of us. Focusing on six important frontiers, Davis describes what we are learning about cells, the development of the fetus, the body's immune system, the brain, the microbiome, and the genome--areas of human biology that are usually understood in isolation. Bringing them together here for the first time, Davis offers a new vision of the human body as a biological wonder of dizzying complexity and possibility.Written by an award-winning scientist at the forefront of this adventure, The Secret Body: How the New Science of the Human Body Is Changing the Way We Live (Princeton UP, 2022) is a gripping drama of discovery and a landmark account of the dawning revolution in human health. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Today I talked to Michael Hannah about his book Extinctions: Living and Dying in the Margin of Error (Cambridge UP, 2021).Are we now entering a mass extinction event? What can mass extinctions in Earth's history tell us about the Anthropocene? What do mass extinction events look like and how does life on Earth recover from them? The fossil record reveals periods when biodiversity exploded, and short intervals when much of life was wiped out in mass extinction events. In comparison with these ancient events, today's biotic crisis hasn't (yet) reached the level of extinction to be called a mass extinction. But we are certainly in crisis, and current parallels with ancient mass extinction events are profound and deeply worrying. Humanity's actions are applying the same sorts of pressures - on similar scales - that in the past pushed the Earth system out of equilibrium and triggered mass extinction events. Analysis of the fossil record suggests that we still have some time to avert this disaster: but we must act now. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Taking over the world is a lot of work. Any supervillain is bound to have questions: What's the perfect location for a floating secret base? What zany heist will fund my wildly ambitious plans? How do I control the weather, destroy the internet, and never, ever die?Bestselling author and award-winning comics writer Ryan North has the answers. In How to Take Over the World: Practical Schemes and Scientific Solutions for the Aspiring Supervillain (Riverhead Books, 2022), he details a number of outlandish villainous schemes that harness the potential of today's most advanced technologies. Picking up where How to Invent Everything left off, his explanations are as fun and elucidating as they are completely absurd.You don't have to be a criminal mastermind to share a supervillain's interest in cutting-edge science and technology. This book doesn't just reveal how to take over the world--it also shows how you could save it. This sly guide to some of the greatest threats facing humanity accessibly explores emerging techniques to extend human life spans, combat cyberterrorism, communicate across millennia, and finally make Jurassic Park a reality.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

In Different: Gender Through the Eyes of a Primatologist (W. W. Norton, 2022), world-renowned primatologist Frans de Waal draws on decades of observation and studies of both human and animal behavior to argue that despite the linkage between gender and biological sex, biology does not automatically support the traditional gender roles in human societies. While humans and other primates do share some behavioral differences, biology offers no justification for existing gender inequalities.Using chimpanzees and bonobos to illustrate this point--two ape relatives that are genetically equally close to humans--de Waal challenges widely held beliefs about masculinity and femininity, and common assumptions about authority, leadership, cooperation, competition, filial bonds, and sexual behavior. Chimpanzees are male-dominated and violent, while bonobos are female-dominated and peaceful. In both species, political power needs to be distinguished from physical dominance. Power is not limited to the males, and both sexes show true leadership capacities.Different is a fresh and thought-provoking approach to the long-running debate about the balance between nature and nurture, and where sex and gender roles fit in. De Waal peppers his discussion with details from his own life--a Dutch childhood in a family of six boys, his marriage to a French woman with a different orientation toward gender, and decades of academic turf wars over outdated scientific theories that have proven hard to dislodge from public discourse. He discusses sexual orientation, gender identity, and the limitations of the gender binary, exceptions to which are also found in other primates.With humor, clarity, and compassion, Different seeks to broaden the conversation about human gender dynamics by promoting an inclusive model that embraces differences, rather than negating them.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Inequality is an urgent global concern, with pundits, politicians, academics, and best-selling books all taking up its causes and consequences. In Inequality: A Genetic History (MIT Press, 2022), Carles Lalueza-Fox offers an entirely new perspective on the subject, examining the genetic marks left by inequality on humans throughout history. Lalueza-Fox describes genetic studies, made possible by novel DNA sequencing technologies, that reveal layers of inequality in past societies, manifested in patterns of migration, social structures, and funerary practices. Through their DNA, ancient skeletons have much to tell us, yielding anonymous stories of inequality, bias, and suffering.Lalueza-Fox, a leader in paleogenomics, offers the deep history of inequality. He explores the ancestral shifts associated with migration and describes the gender bias unearthed in these migrations--the brutal sexual asymmetries, for example, between male European explorers and the women of Latin America that are revealed by DNA analysis. He considers social structures, and the evidence that high social standing was inherited--the ancient world was not a meritocracy. He untangles social and genetic factors to consider whether wealth is an advantage in reproduction, showing why we are more likely to be descended from a king than a peasant. And he explores the effects of ancient inequality on the human gene pool. Marshaling a range of evidence, Lalueza-Fox shows that understanding past inequalities is key to understanding present ones.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Niels Bohr was a central figure in quantum physics, well known for his work on atomic structure and his contributions to the Copenhagen interpretation of quantum mechanics. In From Data to Quanta: Niels Bohr’s Vision of Physics (U Chicago Press, 2021), philosopher of science Slobodan Perović explores the way Bohr practiced and understood physics, and analyzes its implications for our understanding of modern science. Perović develops a novel approach to Bohr’s understanding of physics and his method of inquiry, presenting an exploratory symbiosis of historical and philosophical analysis that uncovers the key aspects of Bohr’s philosophical vision of physics within a given historical context.Ana Georgescu studied astrophysics and physics at Harvard University and is now a science consultant and writer based in New York City. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science