New Books in Science

Can genetics play a role in crafting left social policy? Or should we not touch those ideas ever again–even with a 10 foot pole? Paige Harden’s book, “The Genetic Lottery: Why DNA Matters for Social Equality” makes a forceful case for an egalitarian politics informed by DNA. However, geneticist Joseph Graves critiqued the book, arguing that we do not need sophisticated genetic knowledge to make a more socially just world. On this episode managing producer Marc Apollonio guest hosts, talking to both.—————————-SUPPORT THE SHOW—————————-You can support the show for free by following or subscribing on Spotify, Apple Podcasts, or whichever app you use. This is the best way to help us out and it costs nothing so we’d really appreciate you clicking that button.If you want to do a little more we would love it if you chip in. You can find us on patreon.com/dartsandletters. Patrons get content early, and occasionally there’s bonus material on there too.——————-ABOUT THE SHOW——————For a full list of credits, contact information, and more, visit our about page. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Biomedical research using various animal species and in vitro cellular systems has resulted in both major successes and translational failure. In Model Systems in Biology: History, Philosophy, and Practical Concerns (MIT Press, 2022), comparative neurobiologist Georg Striedter examines how biomedical researchers have used animal species and in vitro cellular systems to understand and develop treatments for human diseases ranging from cancer and polio to Alzheimer’s disease and schizophrenia. Although there have been some major successes, much of this “translational” research on model systems has failed to generalize to humans. Striedter explores the history of such research, focusing on the models used and considering the question of model selection from a variety of perspectives—the philosophical, the historical, and that of practicing biologists.Striedter reviews some philosophical concepts and ethical issues, including concerns over animal suffering and the compromises that result. He traces the history of the most widely used animal and in vitro models, describing how they compete with one another in a changing ecosystem of models. He examines how therapies for bacterial and viral infections, cancer, cardiovascular diseases, and neurological disorders have been developed using animal and cell culture models—and how research into these diseases has both taken advantage of and been hindered by model system differences. Finally, Striedter argues for a “big tent” biology, in which a diverse set of models and research strategies can coexist productively.Rachel Pagones is an acupuncturist, educator, and author based in Cambridge, England. Her book, Acupuncture as Revolution: Suffering, Liberation, and Love (Brevis Press) was published in 2021. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Listen to this interview of John Measey, Researcher at the Centre for Invasion Biology, Stellenbosch University, South Africa. We talk about the needs of early-career researchers and also about our need for early-career researchers.John Measey : "What we really need to know is what a scientific journal is for and what we want it to be for. So, we know, more or less, what it was for and where it came from, but what do we want that to be in the twenty-first century, and how will the journal meet rigor, independence, transparency, and replicability? Because we have a lot more potential now than we've ever had before for making knowledge available, so this means that every single publication that's out there, every piece of scientific work — all of it can be used not only one time by one scientist, but again and again and again by all scientists today and to come. So the question here is, How do we want that to be presented? I don't think that we should lose that interpretive manuscript, that (as we call it) journal paper, because it really gives us the insight of what the people who conducted that research did and what they think about what they did. That is a historical document of the time. But I want to ask too: What else can we get that will really make that paper so much more valuable going on into the future? Let's make the data available, let's make the script for the analysis available, let's make the code available — and there's so much more, because these days scientists are producing so much more digital content. So what do we want journals to do, and how do we want them to interact with this availability, with this big data?"Read and use How to Publish in Biological Sciences Read and use How to Write a PhD in Biological Sciences Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Peter Winkler has been collecting mathematical puzzles since childhood. He has had published two previous collections, and recently he compiled his largest curated collection to date. Mathematical Puzzles (A K Peters, 2021) also takes an alluring new approach to the genre: In the Roman-numbered front matter, 300+ puzzles are presented, roughly in order of increasing difficulty. Fuller discussions of the puzzles are then organized into 24 chapters according to the key insight that leads to their solutions. Each insight gets a brief mathematical treatment, and by the end of each chapter the reader is primed to appreciate an important and kindred mathematical result.In our interview, Dr. Winkler walked me through a handful of puzzles from two chapters. The first, "The Law of Small Numbers", gives a tongue-in-cheek name to the strategy of gaining insight from a smaller version of a larger problem. The puzzles lead up to a discussion of perfect matchings, whose small-number analogues reveal an elegant geometric solution. The second, "Infinite Choice", begins with some variations on hat-guessing puzzles, which turn out to admit surprisingly powerful strategies even among infinitudes of players! The chapter closes with an accessible peek at graph coloring problems.The book is delightfully designed with playful header fonts and illustrations by cartoonist Jess Johnson, through an equally delightful collaboration we took a moment to discuss. As Dr. Winkler aimed, i believe the book will appeal both to the puzzle enthusiast with a limited background in mathematics and to the mathematics enthusiast who, like myself, never really took to puzzles—as well, of course, to those dual enthusiasts whom the author epitomizes.Suggested companion works: How to Solve It: A New Aspect of Mathematical Method by Georg Pólya Martin Gardner’s Mathematical Games: The Entire Collection of his Scientific American Columns Peter Winkler is the William Morrill Professor of Mathematics and Computer Science at Dartmouth College and, for 2019–2020, the Distinguished Visiting Professor for the Public Dissemination of Mathematics at the National Museum of Mathematics. He is the author of 160 research papers, a dozen patents, two previous puzzle books, a book on cryptographic techniques in the game of bridge, and a portfolio of compositions for ragtime piano. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Until the publication of Edwin Hubble’s 1936 book, The Realm of the Nebulae, astronomers believed that the Milky Way was the only galaxy in the universe. Hubble infinitely expanded our understanding of the cosmos and showed that what scientists thought was everything, was really just the beginning. In this episode, MIT professor emeritus Marcia Bartusiak unpacks Hubble’s findings and discusses how they impact the field of astronomy to this day. Marica Bartusiak is Professor of the Practice Emeritus of the Graduate Program in Science Writing at Massachusetts Institute of Technology. She writes on physics and astronomy and her work has been published in National Geographic Magazine, Discover Magazine, Science Magazine, and many others. See more information on our website, WritLarge.fm. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

We are exposed to thousands of toxic chemicals daily. This is no accident; it is by design. They are everywhere – coating our consumer products, in our food packaging, being dumped into our lakes and sewers, and in countless other places. However, for the most part, regulators say that we need not worry.That assessment is based on a simple 500-year-old adage, “the dose makes the poison.” The logic is simple: anything is poisonous, depending on how large a dose. Dosing yourself with a miniscule amount of lead will cause no harm; while drinking an enormous amount of water will kill you. Regulators then try to find safe exposure levels for these chemicals—and they assume a simple, direct relationship (less is fine, more is worse). So, no matter how toxic the chemical, you only need to worry if it passes a certain exposure threshold.But what if that’s wrong?This episode of Darts and Letters predecessor, Cited, asks that question. This episode is a central part of Darts and Letters’ DNA. We’re interested in the politics of science and academia. We like asking questions like who gets to be the expert, how does funding impact research outcomes, that kind of stuff.This is a story about how what one chemical, bisphenol A, or “BPA”, tells us about the politics of science.—————————-SUPPORT THE SHOW—————————-You can support the show for free by following or subscribing on Spotify, Apple Podcasts, or whichever app you use. This is the best way to help us out and it costs nothing so we’d really appreciate you clicking that button.If you want to do a little more we would love it if you chip in. You can find us on patreon.com/dartsandletters. Patrons get content early, and occasionally there’s bonus material on there too.——————-ABOUT THE SHOW——————For a full list of credits, contact information, and more, visit our about page. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

In Molecular Capture: The Animation of Biology (University of Minnesota Press, 2021), Adam Nocek, Assistant Professor in the Philosophy of Technology and Science and Technology Studies at Arizona State University, investigates the collusion between entertainment and scientific visualization in the case of molecular animation. “The very same tools that were invented to animate a character like Shrek or Nemo are now being applied to set in motion protein domains and cellular processes.” Opening with this quote by animator and scientist Gaël McGill, the book retraces the complex genealogy of molecular animation and analyses its pretension to scientific value. While the first half of the book deals with “molecular capture” as the cinematographic process of producing moving images of the molecular world, the second half thinks about that same “capture” as a form of governmental rationality, a kind of apparatus rendering life visible and available down to its most fundamental mechanisms. This discussion leads the author to consider the elusiveness of life and how the current codes of molecular animation are blurring the line between knowledge, data, speculation, and imagination. At the source of fascinating images, granting consumers with the impression of directly accessing the invisible processes defining life, molecular animation stands at the intersection of important questions relating to the history of scientific visualization, the evolving relationship between science and entertainment, and the production of biopolitical forms of governance.Victor Monnin, Ph.D. is an historian of science specialized in the history of Earth sciences. He is also teaching French language and literature to undergraduates. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Today I had the pleasure of talking to Joe Mileti, associate professor of mathematics at Grinnell College. Even if you are not "into" math, you will enjoy this conversation. We talked about how math is not what you think it is. It's not just memorizing formulas and grinding. It's about thinking and, like all thinking, it involves abstraction, logic, using analogies and metaphors, and a bunch of imagination. We also talked about how math is about talking to other mathematicians and doing a kind of "brainstorming." Joes's new book is Modern Mathematical Logic (Cambridge UP, 2022).Marshall Poe is the founder and editor of the New Books Network. He can be reached at marshallpoe@newbooksnetwork.com. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Welcome to the final day of our weeklong deep dive into the politics of education. Today, we’ve got another episode of Cited for you. If you haven’t heard a Cited episode before, it’s the documentary show that came before Darts and Letters and it specialised in immersive storytelling.This piece takes us on a journey through a little-known, long-past set of debates on the nature of science in democratic society: the Science Wars. They may seem lost to time, but some scholars say the Science Wars might just explain how we got our 'post-truth' moment. Learn about the bold hoax that became a determining factor in the Science Wars and how that moment in history might have foretold the wars on science to come.Next week, we’ll be bringing you episodes on a whole new theme - activism and academia. You won’t want to miss it. And you really won’t want to miss our brand-new episodes, launching on the New Books Network from September 18th.—————————-SUPPORT THE SHOW—————————-You can support the show for free by following or subscribing on Spotify, Apple Podcasts, or whichever app you use. This is the best way to help us out and it costs nothing so we’d really appreciate you clicking that button.If you want to do a little more we would love if you chip in. You can find us on patreon.com/dartsandletters. Patrons get content early, and occasionally there’s bonus material on there too.—————————-CONTACT US————————-To stay up to date, follow us on Twitter and Facebook. If you’d like to write to us, email darts@citedmedia.ca or tweet Gordon directly.———-CREDITS———-Today’s episode was produced by Gordon Katic, and edited by Cited's Sam Fenn. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

The process of manipulating the genetic material of one animal to include the DNA of another creates a new transgenic organism. Several animals, notably goats, mice, sheep, and cattle are now genetically modified in this way. In Our Transgenic Future: Spider Goats, Genetic Modification, and the Will to Change Nature (NYU Press, 2022), Lisa Jean Moore wonders what such scientific advances portend. Will the natural world become so modified that it ceases to exist? After turning species into hybrids, can we ever get back to the original, or are they forever lost? Does genetic manipulation make better lives possible, and if so, for whom?Moore centers the story on goats that have been engineered by the US military and civilian scientists using the DNA of spiders. The goat’s milk contains a spider-silk protein fiber; it can be spun into ultra-strong fabric that can be used to manufacture lightweight military body armor. Researchers also hope the transgenically produced spider silk will revolutionize medicine with biocompatible medical inserts such as prosthetics and bandages. Based on in-depth research with spiders in Florida and transgenic goats in Utah, Our Transgenic Future focuses on how these spider goats came into existence, the researchers who maintain them, the funders who have made their lives possible, and how they fit into the larger science of transgenics and synthetics. This book is a fascinating story about the possibilities of science and the likely futures that may come.Rachel Pagones is an acupuncturist, educator, and author based in Cambridge, England. Her book, Acupuncture as Revolution: Suffering, Liberation, and Love (Brevis Press) was published in 2021. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science