People I (Mostly) Admire

Carolyn Bertozzi is a Stanford professor and a MacArthur Genius Grant recipient, known for her groundbreaking work in bioorthogonal chemistry. In a fascinating discussion, she shares her innovative approaches to immune therapy and how glycobiology plays a crucial role in cancer treatment. Carolyn also ponders the allure of a rock star lifestyle versus her scientific career, offering playful insights into her love for music and the importance of women in chemistry. The conversation seamlessly weaves in both personal aspirations and the challenges of translating science into tangible healthcare solutions.

Larry Miller, a former Nike executive and author of "Jump," shares his remarkable journey from being a teenage murder convict to leading Nike's Jordan brand. He discusses the challenges of living with his past while climbing the corporate ladder. Education in prison changed his life, allowing him to become valedictorian. Miller also explores the importance of collaboration and insights in effective leadership at Nike, advocating for educational reforms in the justice system to foster transformation and reintegration.

Michael Lewis, bestselling author known for hits like 'Moneyball' and 'The Big Short', discusses his latest work, 'The Premonition', which critiques the U.S. COVID-19 response. He reflects on the pandemic's failures and emphasizes the importance of preparedness for future crises. Lewis also revisits his earlier work 'Liar's Poker', exploring how his views on Wall Street have evolved over three decades. The conversation touches on personal experiences, the ethical dilemmas faced in finance, and the necessity for improved public health methodologies.

Brad Gregory, a Notre Dame history professor and Reformation expert, joins the conversation to reveal how to make history captivating. He discusses the disconnect between historians and economists, emphasizing the importance of narrative in making historical events relatable. Gregory also explores Martin Luther's lasting influence on modern society and how themes of strategy in sports can mirror historical transformations. With humor, he connects the pursuit of a meaningful life with deeper human connections beyond mere self-interest.

Austan Goolsbee, former chairman of the Obama administration’s Council of Economic Advisors and a seasoned economist who dabbles in improv comedy, shares his unique journey from academia to the heart of government. He reveals how improv techniques have influenced his teaching approach. Goolsbee also candidly reflects on the automotive bailout decision, discussing past skepticism and the high-stakes environment of the Oval Office, while emphasizing the need for diverse perspectives in economic policymaking.

Cassandra Quave, an ethnobotanist from Emory University and author of "The Plant Hunter," dives into the looming crisis of antibiotic resistance, predicting 10 million deaths annually by mid-century. She argues for blending ancient healing methods with modern medicine to tackle this urgent challenge. The discussion explores the urgent need to preserve traditional practices while innovating new solutions. Quave also shares her personal journey of transforming insecurities into creativity, highlighting the power of collaboration in medicine and the importance of responsible consumer choices.

Carl Hart, a neuroscientist and psychology professor at Columbia University, argues that recreational drug use, including harder substances like heroin and cocaine, is a fundamental right. He advocates for the regulation of illicit drugs to ensure safety and quality, while challenging societal perceptions of addiction. The dialogue delves into how personal freedom intersects with drug use, the complexities of addiction, and the correlation between drug laws and social attitudes. Hart offers fresh insights on drug policy reform and stimulates a conversation about responsible usage.

Amaryllis Fox, a former CIA operative and author of "Life Undercover," shares her fascinating journey in intelligence and empathy. She discusses the personal growth gained through her experiences, including volunteering with freedom fighters and her unique training as an agent. Fox delves into the evolving challenges of modern terrorism, emphasizing the role of technology and the necessity of understanding human emotions. She also explores insights from her Netflix series, advocating for a compassionate view of those involved in the drug trade.

In this engaging discussion, a listener shares their experience with seeking advice from various guests. They question the value of wisdom offered by successful individuals and whether it genuinely applies to everyday life. Topics range from the balance of ambition and authenticity to the freedom found in quitting when necessary. The conversation even touches on the controversial implications of parenting in our changing climate, sparking intense reflections among the audience. It's a thought-provoking exploration of finding fulfillment and learning from failure.

In this entertaining conversation, Richard Thaler, a Nobel laureate and pioneering behavioral economist, shares his insights on the complexities of decision-making. He humorously explores how emotions influence our choices and the importance of nudges in shaping behavior. Thaler admits economists often miss their blind spots while dissecting the evolution of behavioral economics. He emphasizes the necessity of broader systemic changes in areas like climate change, all while maintaining a refreshingly optimistic outlook.