Ava DuVernay, acclaimed director and screenwriter, discusses her latest film 'Origin' which is an adaptation of a nonfiction book. She secured funding for the film from philanthropists instead of major Hollywood studios. They explore the importance of recognizing oppression beyond race, the state of democracy in the US, the dangers of becoming numb to threats, examining assumptions in DEI programs, and the impact of alternative funding on their filmmaking process.

Former PBS NewsHour anchor and current senior correspondent, Judy Woodruff, discusses polarization, politics, and the media. Topics include the roles of politicians and the media in polarization, journalists being truthful and not neutral, media consolidations and cuts to public broadcasting, Donald Trump's impact on American politics, the role of polarization in politics and media, the decline of local journalism, and the importance of panel discussions to explore different perspectives.

Pennsylvania Attorney General Josh Shapiro discusses defending the state election process, preparing for a likely Trump/Biden rematch, launching a pilot project for using generative AI in government, and reflecting on the surge in antisemitism. Other topics include the situation at the southern border, AI in state governments, using technology to enhance the workforce, and actions of the Democratic governor of Pennsylvania. The speaker also touches on the Eagles' collapse and sports preferences.

Heather Cox Richardson, historian and professor, discusses the rise of Donald Trump, the state of American democracy, and the changing future of the Republican Party. They also explore President Biden's transformative policies, their recent interviews with him, and the potential impact of de-centering white heteronormative men on American democracy.

Joe Green, President of the Psychedelic Science Funders Collaborative, discusses the therapeutic potential of psychedelics and the need for accountability in the industry. Topics include mental health treatment, power dynamics, stories and public perception, funding for research, and licensing requirements for treatment centers.

Computer Scientist Fei-Fei Li discusses the importance of a humane approach to AI, the lack of diversity in the tech industry, the impact of AI on society, the rise of AI-generated misinformation, the applications of ambient intelligence in healthcare, and the decline of women in tech and lack of diversity in AI.

Experts analyze Trump's 2024 strategy, legal troubles, and dangerous rhetoric. They discuss his goals, maintaining a strong base, and a campaign of retribution. The conversation also touches on his romanticized gangster image, media coverage, and voters' role in the Trump era.

Former New York Times global health reporter Donald G McNeil Jr. discusses COVID-19 origins, the need for a Pentagon for Disease, and his own controversial departure from The New York Times.

Unpacking the drama at OpenAI, the impact of the 2024 election on the tech industry, contrasts between Trump and Biden, media challenges with disseminating information about Trump, Elon Musk's concentration of power, and a discussion on Barry Diller's interview and Google monopoly.

Author Mark Chiusano joins Preet to discuss his new book about George Santos, a former congressman's life of deception, exploring the motivations behind his lies and the implications for the political system in America. The chapter explores Santos's exceptional level of dishonesty, his psychological aspects, and his expulsion from Congress with speculation on his second act. It also discusses the failings of the system that allowed his election and the challenges of recognizing deception.