PsychRounds: The Psychiatry Podcast

Welcome back! On todays episode, we will discuss hydroxyzine (Atarax, Vistaril), a frequently used medication for anxiety.References:https://pubmed.ncbi.nlm.nih.gov/9616188/https://pubmed.ncbi.nlm.nih.gov/27998379/https://pubmed.ncbi.nlm.nih.gov/21154375/https://pubmed.ncbi.nlm.nih.gov/1345410/

Join Dr. Matthew Bernstein, a Harvard-affiliated psychiatrist and chief medical officer at Accord and Ellenhorn Clinics, as he dives into metabolic psychiatry, a groundbreaking field blending mental health with metabolic processes. He shares insights on the ketogenic diet, detailing its history and potential benefits for psychiatric disorders. Learn about the vital role of ketone levels in treatment and the relationship between diet and heart health. Dr. Bernstein also advocates for nutritional reforms in mental health care, emphasizing the importance of holistic approaches.

Delve into the fascinating world of the salience network, a crucial brain system that helps us prioritize stimuli and influences decision-making. Discover its role in schizophrenia, including how dopamine spikes relate to psychotic symptoms and hallucinations. The discussion also explores the complexities of auditory and visual hallucinations, shedding light on their connection to psychiatric disorders. Finally, learn about the implications of the salience network in conditions like autism and PTSD, where heightened sensitivity can dramatically impact cognition.

On todays episode we will be discussing Transcranial Magnetic Stimulation with a very special guest, Dr. Jonathan Downar. We will also discuss the ONE-D and THREE-D trails.Three-D Trial: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30295-2/abstract’One-D Trial: https://www.researchsquare.com/article/rs-5679327/v1SAINT TMS: https://psychiatryonline.org/doi/10.1176/appi.ajp.2019.19070720

Dive into the fascinating dynamics of the Central Executive Network and its interplay with the Default Mode Network. Discover how dopamine influences focus and stimulus prioritization through engaging examples. Learn about brain areas critical for problem-solving and attention regulation, especially in relation to ADHD. Explore essential tests for assessing executive function, like the Stroop and Wisconsin card sorting tests. Finally, uncover how aging affects brain function and the vital role of cognitive engagement in maintaining cognitive health.

On today's episode we have a special international guest, Dr. Pouya Movahed Rad from Lund University in Sweden. We will be discussing Electroconvulsive therapy (ECT) and the Ket-ECT, and ELEKT-D studies. ELEKTD:https://www.nejm.org/doi/full/10.1056/NEJMoa2302399KET-ECT: https://pubmed.ncbi.nlm.nih.gov/35020871/Comparison: https://pubmed.ncbi.nlm.nih.gov/38114073/

Dive into the intriguing world of the Default Mode Network (DMN) and its surprising impact on creativity, memory, and self-awareness. Discover how the DMN influences mental health conditions like depression and anxiety, exploring cognitive distortions and therapeutic methods such as cognitive behavioral therapy and mindfulness. Uncover the relationship between personality traits and mental health vulnerability. Plus, learn about innovative treatments, including psychedelics and physical exercise, that can help balance the DMN's activity for better mental well-being.

The discussion focuses on metformin's application in psychiatry, particularly in combating weight gain from antipsychotic medications. Recent guidelines emphasize careful monitoring for side effects, like gastrointestinal issues and lactic acidosis. The podcast dives into dosing strategies and the findings from recent studies, highlighting individual patient factors in treatment decisions. Seasonal weight trends and their impact on mental health are also examined, along with metformin's intriguing potential benefits for psychiatric symptoms.

On today’s special guest episode, we’ll be exploring the topic of nitrous oxide with Dr. Charles Conway and Dr. Vasilis Hristidis.https://medicine.washu.edu/news/laughing-gas-relieves-symptoms-in-people-with-treatment-resistant-depression/https://pmc.ncbi.nlm.nih.gov/articles/PMC5825282/https://pubmed.ncbi.nlm.nih.gov/34108247/https://pubmed.ncbi.nlm.nih.gov/25577164/

In today’s episode, we explore ketamine’s therapeutic potential with Dr. Joshua Rosenblat, a leading expert and faculty member at the University of Toronto’s Department of Psychiatry (learn more). https://x.com/jd_rosenblat?lang=enhttps://pubmed.ncbi.nlm.nih.gov/35688035/https://pubmed.ncbi.nlm.nih.gov/39608193/