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Talking Precision Medicine

Latest episodes

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Oct 10, 2019 • 39min

The Genomics of Justice with David Mittelman | Talking Precision Medicine #15

Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine.  This show is brought to you by Genialis, and Rafael, our CEO, is your host. Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics.  Today our guest is David Mittelman. David is CEO of Othram, the first genomics-based forensics company. David is also a serial genomics entrepreneur, and, like Genialis, based in Houston. In this episode, David explains his vision for disrupting the state of the art in forensics identification using genomics, deep sequencing and machine learning. A bit of a departure from the usual themes around medical applications of data and data science.
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Sep 17, 2019 • 36min

Garbage in, garbage out? Solve data preprocessing with Gabe Musso | Talking Precision Medicine #14

Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine.  This show is brought to you by Genialis, and Rafael, our CEO, is your host. Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics.  Today our guest is Gabe Musso. Gabe is Chief Scientific Officer of BioSymetrics, a Toronto-based biomedical AI company empowering healthcare and R&D innovation.  In this episode, Gabe tells us how BioSymetrics is working to clean up data clean up, by applying a rigorous product framework to data preprocessing. 
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Jul 23, 2019 • 35min

Twenty-two suicides, every damn day with Yusuf Henriques | Talking Precision Medicine #13

Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host. Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics. Today our guest is Yusuf Henriques. Yusuf is co-founder and CEO of TruGenomix, a precision medicine company focused on the early detection and prevention of PTSD in military veterans and first responders. In this episode, Yusuf reminds us that every day counts. Because every day there are 20 to 22 veteran suicides. This is what keeps Yusuf up at night, and keeps him pushing on all fronts to innovate a solution.
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Jun 14, 2019 • 40min

Organizing the world’s variant data for genomic medicine with Mark Kiel | Talking Precision Medicine #12

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.  Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics.  Today we speak with Mark Kiel. Mark is the founder and Chief Scientific Officer at Genomenon where he shepherds the product vision and implementation of the Mastermind suite of software tools. He completed an MD / PhD  fellowship in Molecular Genetic Pathology at the University of Michigan.  In this episode, Mark describes the genesis of his vision to organize the world’s molecular data and his journey to realize the promise of genomic medicine.
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May 28, 2019 • 28min

The evolving business landscape of health-tech with Luba Greenwood | Talking Precision Medicine #11

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.  Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics.  Today we speak with Luba Greenwood, who works in Strategic Business Development and Corporate Ventures at Verily, an Alphabet company.  Luba brings to Google her experience in pharmaceutical, biotechnology, and digital health industries. Not to mention her expertise in building and investing in innovative technology companies.  She is on the Board of MassBio and Brooklyn ImmunoTherapeutics, and serves as an Advisor to the Dana Farber Cancer Institute. In this episode, we dive into Luba’s work across the intersections of healthcare and technology.
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Apr 30, 2019 • 31min

The hottest time in gene therapy, ever! with Nicole Paulk | Talking Precision Medicine #10

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.  Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics.  Today we speak with Dr. Nicole Paulk. Nicole is an assistant professor at the University of California San Francisco, and the Advisory Lead for Genome Engineering at Chan Zuckerberg Biohub.  Nicole’s lab builds technologies to advance the entire field of viral gene therapy. They are a force behind the rising tide lifting the gene therapy industry. She is also committed to training the next generation of scientist innovators. 
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Apr 2, 2019 • 29min

Building trust in rare disease with Julie Walters | Talking Precision Medicine #09

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.  Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics.  Today we speak with Julie Walters. Julie is the founder of Raremark, an information hub about rare disease for patients and their families. She has a degree in molecular genetics and a background in popular journalism… and is an entrepreneur by nature. In fact, she was a Female Entrepreneur of the Year at the UK’s 2017 Enterprise Awards.  Julie believes in harnessing the power of families affected by a rare disease, and our discussion covers many of the ways Raremark aims to do just that. 
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Mar 5, 2019 • 37min

Standing up the Alliance for AI in Healthcare with Annastasiah Mhaka | Talking Precision Medicine #08

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host. Genialis is focused on data integration and predictive modeling of disease biology… to help accelerate the discovery and de-risk the development of novel therapeutics. Today’s podcast is a special episode of Talking Precision Medicine, dedicated to the Alliance for Artificial Intelligence in Healthcare. The A-A-I-H saw its official hard launch at JP Morgan this past January, with a standing-room-only panel discussion at the Biotech Showcase. Our guest today is Dr. Annastasiah Mhaka, a Senior Advisor at Adjuvant Partners and the muscle behind standing up the AAIH. The Alliance is a global organization that aims to improve patient quality of life by creating more effective, sustainable, and accessible healthcare. Through its work on education, regulatory issues, technology standards, and more, the AAIH will foster the responsible development of emerging industry segments poised to have a tremendous impact across the healthcare spectrum. At the end of our conversation with Annastasiah, we include some bonus material recorded at The Future of AI-Powered Healthcare panel discussion at JPM. Full disclosure— Genialis is a founding member of the AAIH, and its CEO, Rafael Rosengarten, is a board director.
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Feb 19, 2019 • 39min

Modeling systems from organoids to EHRs with Olivier Elemento | Talking Precision Medicine #07

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host. Genialis is focused on data integration and predictive modeling of disease biology… to help accelerate the discovery and de-risk the development of novel therapeutics. Today we speak with Olivier Elemento. Olivier is the Director of the Englander Institute for Precision Medicine, as well as Associate Director of the Institute for Computational Biomedicine, both at Weill Cornell Medicine. He is also co-founder of OneThree Biotech. Olivier is a practitioner par excellence, in applying advanced analytics to large genomic and patient datasets.  Our conversation covered a lot of ground, including curated knowledge bases, patient consent, breakthroughs in preclinical models, and even AR/VR.
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Feb 5, 2019 • 31min

Where were you when the FDA approved CAR-T? with Patrick Hanley | Talking Precision Medicine #06

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host. Genialis is focused on data integration and predictive modeling of disease biology… to help accelerate the discovery and de-risk the development of novel therapeutics. Today we speak with Patrick Hanley. Patrick works at the Children’s National Hospital in Washington DC, where he serves as the director of Good Manufacturing Practices for Immunotherapy. He is also a co-founder and vice president at Mana Therapeutics — a cell therapy company harnessing our immune cells to combat cancer. He is an expert in designing and manufacturing cell therapies... and was once a fierce competitor on the Houston indoor soccer circuit.  We talk about the leaps and bounds of progress in cell therapy, and the challenges—including discovery, manufacturing, and distribution—that lay ahead.

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