Today I began my discussion with Dr. Adrian Perkel about his new book Unlocking The Nature of Human Aggression: A Psychoanalytic and Neuroscientific Approach (Routledge, 2024) “Aggression is to the mind what the immune system is to the body. It doesn’t seek the fight.” With this perfect mind-body analogy Dr. Perkel proposes a clear way to think theoretically and work clinically with aggression. Throughout the book he links Freud’s formulations of the psyche with contemporary physics and biochemistry. Perkel’s assertion that “Where the aggressive drive goes, so therein lies the solution to many of the psychological problems that present to us in life” is broadly summarized in three essential points:1. The aggressive drive in the human psyche has the aim of reducing stimuli and excitations brought on by internal and external impingements - it is not looking for a fight.2. What constitutes a threat or impingement is not necessarily objective - in fact it is always filtered through subjective experience and the UCS associations that are revisited repeatedly giving rise to a lens through which experience is filtered.3. This experience is driven by memory traces of experience that embed themselves in the UCS and are revisited and hence enacted in a repetitive manner.“My argument is that what wraps all those three points together is that you have life drive needs yes but they're often unfulfilled they're often frustrated and then we need a second mechanism which is what Freud called the death drive.” Acknowledging that the death drive is contentious in psychoanalysis “in neuroscience it's not contested.”I knew going into this interview that we would only discuss a few concepts and elaborations from his book. For more of Dr. Perkel’s writing and webinar on this book please go here and here.  Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

This book is available open access here. The Brain Abstracted: Simplification in the History and Philosophy of Neuroscience (MIT Press, 2024), Mazviita Chirimuuta argues that the standard ways neuroscientists simplify the human brain to build models for their research purposes mislead us about how the brain actually works. The key issue, instead, is to figure out which details of brain function are relevant for understanding its role in causing behavior; after all, the biological brain is a highly energetically efficient basis of cognition in contrast to the massive data centers driving AI that are based on the simplification that brain functionality is just a matter of neuronal action potentials. Chirimuuta, who is a senior lecturer in philosophy at the University of Edinburgh, also argues for a Kantian-inspired view of neuroscientific knowledge called haptic realism, according to which what we can know about the brain is the product of interaction between brains and the scientific methods and aims that guide how we investigate them. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Of all the mental illnesses, schizophrenia eludes us the most. No matter the strides scientists have made in neurological research nor doctors have made in psychiatric treatment, schizophrenia remains misunderstood, almost complacently mythologized. Without a reason for the illness, patients feel even more alienated than they already do, families are left hopeless, and doctors struggle to provide accurate care. Steven Lesk, though, after a medical career dedicated to those affected by schizophrenia and a determination to find the answer to its existence, presents a groundbreaking theory that will forever change the lives of the mentally ill. In Footprints of Schizophrenia: The Evolutionary Roots of Madness (Prometheus, 2023), Lesk threads evolutionary evidence with neurological evidence, turning the mysteries of our minds into a tapestry of logic. With his breakthrough theory and this unprecedented book, Lesk will invite necessary cultural dialogue about this stigmatized illness, provoke new psychiatric and pharmacological research, and provide unequivocal comfort to those afflicted and affected by schizophrenia.Lesk's "primitive organization theory" is based in human evolution, from Neanderthals to Homo sapiens, and the specific changes to our brains after the emergence of language. We have existed in human-like form for six million years, but we've only had language for 50,000; within the vast span of evolutionary time, that's hardly any time at all. Lesk elucidates us to the hormones affected by language, especially dopamine, and with brilliant clarity, connects human evolution, our brain affected by language, and those with schizophrenia whose dopamine doesn't flow in our new, adaptive way. In other words, the twenty million people who have schizophrenia in the world don't suppress dopamine in the way evolution has trained us, so their brains don't process language well and function as if they're in a hallucinatory, delusional dream state. Not only will Lesk's theory focus treatment efforts for schizophrenia, but it will also affect that of other dopamine-related mental illnesses like Alzheimer's, Parkinson's, Huntington's chorea, Tourette's, ADD, and more. Publishing Lesk's work will usher in a new era of psychiatric understanding, one that the field and the public desperately needs. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Camilla Nord, a neuroscientist at the University of Cambridge and leader of the Mental Health Neuroscience Lab, dives into the science of mental health. She discusses how our brains strive for balance amidst life's chaos and how different interventions, from antidepressants to simple mood-lifting activities, work at a neurological level. Nord explores the connection between physical and mental health, the surprising power of belief, and innovative treatments like non-invasive electrical stimulation. Her insights redefine how we approach mental well-being.

Your mental health is as important as your physical health and, in times of stress, it's vital to have enhanced cognition and reserves of resilience. Brain Boost: Healthy Habits for a Happier Life (Cambridge UP, 2025) is packed with practical tips, based on scientific evidence, that will teach you how to implement lifestyle strategies that will improve your brain health, cognition, and overall wellbeing. Covering the benefits of exercise, diet, sleep, social interactions, kindness, mindfulness, and learning, you will discover how adopting habits to improve these areas of your life at an early age will lead to a longer, healthier life. Embracing these simple strategies to prioritise your brain health and wellbeing is essential for a fulfilling life, with lifestyle choices playing a significant role in promoting resilience, creativity, and overall quality of life across all ages. For anyone seeking to lead a fulfilling life through happiness, health, and personal growth, this is the book for you. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

In this conversation, Charles Foster, a legal scholar and naturalist, shares insights from his adventurous book 'Being a Human.' He explores how prehistoric humans lived as hunter-gatherers, experiencing life in the Upper Paleolithic era. Foster reflects on the impact of the shift to agriculture during the Neolithic period, emphasizing its consequences on community and creativity. He also examines the Enlightenment’s effect on human consciousness, lamenting a disconnection from nature and the richness of our senses, urging a return to a more empathetic and engaged existence.

Andrea Scarantino, a Professor of Philosophy at Georgia State University, leads a thought-provoking discussion on the complexities of emotion theory. He delves into the historical and contemporary frameworks surrounding emotions, sharing insights from a vast collection of scholars from diverse fields. Key topics include the cultural nuances of emotions like 'amai' and 'saudade,' the challenges in defining clinical depression, and the interplay between philosophy and emotional understanding. Scarantino advocates for an integrated approach, highlighting emotions' pivotal role in human behavior.

People with dementia are uniquely qualified to discuss the challenges of their condition and the features of effective support, but their voices are all too often drowned out in research and debates about policy. According to People with Dementia at the Heart of Research: Co-Producing Research through The Dementia Enquirers Model (Jessica Kingsley Publishers, 2024) by Rachael Litherland & Philly Hare, it's time for that to change.Dementia Enquirers is an ambitious and novel programme of work which has tested out what it means for people with dementia to lead research and has developed a new 'driving seat' approach to co-research.This ground-breaking book features 26 research projects led by groups of people with dementia, supported by group facilitators and academics, to make their voices heard. Topics include giving up driving, GP dementia reviews, living alone with dementia, and using AI platforms such as smart speakers. The book also describes how people with dementia shaped the entire programme, and addressed head-on issues such as ethics approval processes and complex research language. The book is a key read for anyone involved in dementia support, this research brings the voices of people with dementia to the fore to explore their experiences of researching the condition.This interview was conducted by Dr. Miranda Melcher whose new book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Anneli Jefferson, a philosopher specializing in the intersection of mind and mental health, dives into the complexities of classifying mental disorders as brain disorders. She challenges the reductionist view that links all mental dysfunction directly to brain issues. Jefferson advocates for a broader understanding that considers psychological factors influencing what is deemed dysfunctional. She also discusses societal perceptions of responsibility and how labels around mental health can shape treatment and personal accountability, urging a more nuanced approach.

In his marvelous new book, When Animals Dream: The Hidden World of Animal Consciousness (Princeton UP, 2023), David Peña-Guzmán (SF State as well as the lovely philosophical podcast Overthink) offers up something new in animal studies--"a philosophical interpretation of biological subjectivity." Although we share no linguistic schema with animals there is lots more evidence than just YouTube (octopuses, dogs, signing chimpanzees, brain scans of dreaming birds etc) to suggest oneiric behaviors and underlying mental states occur all over the animal kingdom. So, David discusses with John his interest in using dreaming as a window into consciousness. Here is what it means that we are not alone in our dreams...David details the "flattening and impoverishing effect on the natural sciences" wrought by 20th century behaviorist paradigms. He also expresses skepticism about the likelihood of AI ever achieving more than a "zombie" state; it now and perhaps always will profoundly differ from animals' varied experiences of our shared world.The biological commonality that most strikes David is the idea it is logically inconceivable that there might be a dreamer devoid of consciousness or sentience. Dreaming, he argues may be the key to acknowledging animal's "moral considerability"--the right to have their consciousness, sentience and in the deepest sense their standing taken into account. . Finally David admits to a feeling of tragedy in writing this book: he has had to engage with experimentation that crosses boundaries in animal treatment in order to make the case for those boundaries. He understands his decision as tragic because either way--to engage or to ignore the science--would be to lose something.Mentioned in the episode:New Wave of "inner space" SF authors who focus on the alien nature of humanity itself: J. G. Ballard, Philip K. Dick, and John's hero Ursula Le Guin.Recallable Books: Susana Monso, Playing Possum a newly translated book on the ways that animals mourn their beloveds. Charles Darwin, Descent of Man and The expression of the emotions in man and animals (both 1872) are two of the crucial 19th century texts begin to think of animals as complete subjects. Charles Darwin as an early theorist of biosemiosis who deserves, Jain and David agree, to be reactivated. Listen and Read here. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience