Mayo Clinic Talks

Host: Darryl S. Chutka, M.D. Guest: Robert L. Scott, M.D., Ph.D. Pulmonary hypertension is an important medical condition and often underrecognized in primary care. It has a variety of causes, and its most common presenting symptom is dyspnea. As primary care clinicians, we often see patients with symptoms of dyspnea and pulmonary hypertension is not a health problem we commonly encounter. Yet, early recognition and diagnosis is important and has major implications for patient outcomes. What are some clues that a patient might have pulmonary hypertension? What are its most common causes and what are the potential complications if it goes unrecognized? These are some of the questions I’ll be asking my guest, Robert L. Scott, M.D., Ph.D., from the Department of Cardiovascular Medicine at the Arizona campus of the Mayo Clinic as we discuss “Pulmonary Hypertension”. ** Course link-- https://ce.mayo.edu/pulmonary-medicine/content/mayo-clinic-pulmonary-hypertension-symposium-2025 **Seats are limited, so visit our website to register now!  Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 

Host: Denise M. Dupras, M.D., Ph.D. Guest: Jewel J. Samadder, M.D., Gastroenterologist and Professor, Mayo Clinic In this episode of Mayo Clinic Talks, Dr. Denise Dupras interviews Dr. Jewel Samadder about colon cancer, with a focus on how genetics and family history influence cancer risk and screening strategies. Dr. Samadder emphasizes empowering primary care providers to identify patients who may benefit from genetic evaluation and early colonoscopy. He encourages clinicians to take thorough family histories and use them to guide screening strategies, helping catch cancer early — or prevent it entirely. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP Guest: Nicole Callahan, APRN, CNP, MS In this episode, along with guest Nicole Callahan, APRN, CNP, MS, we explore reproductive health challenges. Starting with the different types of miscarriage—identifying their unique anatomic changes, symptoms, and outcomes. We will cover the basics of both female and male infertility, including when it’s the ideal time to refer patients for specialized care. Finally, we explore ectopic pregnancy, discussing common locations, risk factors, clinical presentation, diagnostic approach, and treatment options. By the end of this podcasts, listeners will be able to:  Identify the differences in anatomic changes, symptoms, and outcomes in the types of miscarriage. Understand the basics in female and male infertility and when to refer for more advanced care. Describe an ectopic pregnancy in regard to most common location, risk factors, signs and symptoms, diagnosis, and treatment options. Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development  

Dr. Saad J. Kenderian, a hematology consultant at the Mayo Clinic, discusses the revolutionary CAR-T cell therapy, which modifies T-cells to target blood cancers like leukemia. He emphasizes patient selection and treatment monitoring, while exploring the therapy's potential for autoimmune diseases. The conversation delves into cytokine storms, linking lessons from COVID-19 to cancer treatment challenges. Additionally, Kenderian addresses the need for increased awareness about CAR-T therapy and its accessibility hurdles, highlighting its transformative potential for many patients.

Host: Danielle O’Laughlin, PA-C, MS Guest: Jenna Wygant, APRN, CNP, DNP In this episode, Jenna Wygant, APRN, CNP, DNP, walks listeners through the most common types of vaginitis, helping providers to confidently differentiate between them. We’ll explore the definitions, causes, risk factors, signs and symptoms, as well as diagnostic methods and treatment options for each condition. Comparing the features of these common vaginitis conditions will be emphasized throughout the episode. By the end of this podcasts, listeners will be able to: Differentiate common vaginitis conditions. Understand the definition, causes/risk factors, signs and symptoms, diagnosis, and treatment for common vaginitis conditions. Identify features that help compare common vaginitis conditions. Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP Guest: Jenna Johnson, APRN, CNP, DNP In this episode, we focus on understanding and differentiating common vulvar conditions with guest Jenna Johnson, APRN, CNP, DNP. We will cover how to recognize conditions such as risk factors, signs and symptoms, and gain insight into how these conditions are diagnosed and treated. We’ll also highlight helpful ways to compare these common vulvar health conditions. By the end of this podcast, listeners will be able to: Differentiate common vulvar conditions. Understand the definition, causes/risk factors, signs and symptoms, diagnosis, and treatment for common vulvar conditions. Identify features that help compare common vulvar conditions. Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Danielle O’Laughlin, PA-C, MS Guest: Jenna Wygant, APRN, CNP, DNP Guest, Jenna Wygant, APRN, CNP, DNP, joins us to explore the full spectrum of contraception options - from natural family planning to non-hormonal and hormonal methods. For each type of contraception, an understanding of how each type works, their efficacy, and the potential risks and benefits will be covered. We also break down the different types of emergency contraception and considerations to review when consulting with patients. By the end of this podcast, listeners will be able to:  Define natural family planning, non-hormonal, and hormonal contraceptives. Understand the use, efficacy, mechanism of action, and risks and benefits for the different types of contraception. Explain the types and uses of emergency contraception. Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP Guest: Jissy Cyriac, M.D. In this episode, guest Jissy Cyriac, M.D., will walk us through the complexities of menstrual health by comparing a normal menstrual cycle with the key causes of abnormal uterine bleeding and menopause. Recognizing the signs, symptoms, and treatment options for conditions like endometriosis, adenomyosis, and endometrial hyperplasia. Plus, we’ll highlight essential buzzwords, the gold-standards and helpful ways to help solidify understanding of key aspects of gynecologic health for menstrual cycles, abnormal uterine bleeding causes, and menopause. By the end of this podcasts, listeners will be able to: Differentiate the normal menstrual cycle versus causes of abnormal uterine bleeding and menopause. Recognize the signs and symptoms, diagnosis, and treatment options for a few of the abnormal uterine bleeding causes including endometriosis, adenomyosis, and endometrial hyperplasia. Identify BUZZ words, gold standards, and helpful ways to remember components of the normal menstrual cycle, abnormal uterine bleeding causes, and menopause. Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP Guest: Danielle O’Laughlin, PA-C, MS In this episode, along with host/guest Danielle O’Laughlin, PA-C, MS, we will discuss benign, inflammatory breast conditions. We will cover how to differentiate between common issues such as mastitis, breast abscess, fat necrosis, galactorrhea, and gynecomastia. We’ll walk through the key signs and symptoms to watch for and explore how each condition is diagnosed and treated. This episode offers valuable insights into these non-cancerous yet very important conditions. By the end of this podcasts, listeners will be able to: Differentiate the benign, inflammatory breast conditions including mastitis, breast abscess, fat necrosis, galactorrhea, and gynecomastia. Recognize the signs and symptoms for benign, inflammatory breast conditions. Summarize the diagnosis and treatment options for benign, inflammatory breast conditions. Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Host: Darryl S. Chutka, M.D. Guests: Cadman L. Leggett, M.D., and Chamil C. Codipilly, M.D. Occasional heartburn from gastroesophageal reflux is usually nothing more than an occasional nuisance for most patients.  However, when the reflux becomes chronic, it can become more serious.  One complication is Barrett’s esophagus. On occasion, Barrett’s can develop into esophageal adenocarcinoma, an aggressive malignancy with a survival rate of only around 20% at 5 years.  Although usually seen in those with chronic acid reflux, Barrett’s can occasionally occur in those without any clinical evidence of acid reflux.  When should a patient with acid reflux receive an upper endoscopy?  What’s the significance of finding Barrett’s esophagus on an endoscopy?  How often does Barrett’s develop into esophageal cancer and does treatment prevent this from happening?  In this podcast, these are just some of the questions I’ll be asking our guests, Cadman L. Leggett, M.D., and Chamil C. Codipilly, M.D., both from the Division of Gastroenterology and Hepatology at the Mayo Clinic as we discuss Barrett’s Esophagus. Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development