Mayo Clinic Talks

Guest: Daniel B. Ryssman, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Generally, we take our feet for granted. It’s not unusual for a person to take 8- to 10-thousand steps per day. That translates to over 115,000 miles in a lifetime. By the time we reach 70 years old, the average person will have walked the equivalent of 4 times around the globe. Yet, we stop taking our feet for granted when they hurt, and it’s estimated that 75% of Americans will experience foot problems of varying degrees of severity during their lifetime. In this podcast, we’ll discuss foot and ankle pain with Daniel Ryssman, M.D., an orthopedist and sports medicine physician from Mayo Clinic. We’ll review some of the common injuries to the ankle such as sprains and fractures as well as common chronic conditions of the foot such as plantar fasciitis and bunions. Dr. Ryssman delves into the best ways to prevent, diagnose, and treat these conditions as well as what, if any, imaging to order. Specific topics discussed: Ankle sprains Ankle fractures Achilles’ tendon rupture Plantar fasciitis Bunions Metatarsalgia Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

This episode is shared from Mayo Clinic Q&A and was recorded June, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    If you've been vaccinated for COVID-19, you're able to go shopping, eat in restaurants and travel on airplanes without the same worry of becoming infected with COVID-19 that existed just months ago. But for those who are unvaccinated, getting infected with COVID-19 — even with just minor symptoms — should be a concern, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "For those who have been vaccinated, life is resuming back to a sense of normalcy," says Dr. Poland. "But for the unvaccinated, they now live in a dangerous phase of the pandemic, where we're seeing circulating variants that are much more transmissible and may cause worse cases of the disease than what happened last year at this time. I think the people who are unvaccinated may not realize that." In this Mayo Clinic Q&A podcast, Dr. Poland also offers information on more COVID-19 studies underway and he talks about COVID-19 vaccine research protocols that will be able to help scientists with other vaccine research, such as HIV vaccine research. Also, he answers listener questions, such as, "Does someone who has already been infected with COVID-19, really need to be fully vaccinated for COVID-19 or would just a booster be needed?" AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Daniel Saris, M.D., Ph.D. (@sarisnl) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Osteoarthritis of the knee is extremely common, and it’s estimated that 1 in 2 people are likely to develop symptomatic knee osteoarthritis in their lifetime. Its known that damaged cartilage is the precursor to osteoarthritis. Many individuals have had partial or complete meniscectomies for meniscal tears in the past and those individuals were then likely to eventually develop knee osteoarthritis. What if damaged cartilage was repaired instead of surgically removed? Could that be an effective treatment recommendation we could give to our patients to help prevent or treat osteoarthritis? Our podcast guest today is Dr. Daniel Saris and he has some fascinating information related to cartilage damage and repair using regenerative medicine techniques. Specific topics discussed: How meniscal damage relates to osteoarthritis Ability of cartilage to repair itself when damaged Repairing a damaged meniscus instead of a partial or complete meniscectomy Specific techniques of repairing cartilage Success in treating patients with cartilage repair Future treatment options for osteoarthritis using regenerative medicine  Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Erin K. O'Brien, M.D. (@ErinOBrienMD)  Host: Amit K. Ghosh, M.D. (@AmitGhosh006)  Erin O’Brien, M.D., division chair of Rhinology in Rochester, MN, joins us again to provide an evidence-based update on anosmia and its prevalence in post-COVID patients. She reviews the postulated mechanism by which anosmia occurs in this group of patients, and how this effects patients’ safety, mental health, and overall wellbeing. Dr. O’Brien also gives an overview of treatment options, such as various methods of olfactory training, and what physicians need to know when counseling their patients with post-COVID anosmia.  Additional resources:  Video on olfactory training: https://www.youtube.com/watch?v=Qrr0so6pFOs  Abscent – resources for patients with anosmia: https://abscent.org/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Shane A. Shapiro, M.D. (@ShaneShapiroMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Musculoskeletal pain is extremely common and when severe, patients often gain significant benefit from joint replacements. However, until our patients reach the point where surgery is an option, our efforts to help patients with the chronic joint pain often leave much to be desired. A relatively new treatment approach has appeared in the past decade, musculoskeletal regenerative medicine. But does the research back up the numerous claims of benefit? This podcast will review the current treatment options available and future potential of regenerative medicine for musculoskeletal problems with Dr. Shane Shapiro, a sports medicine physician in the Department of Orthopedics at the Mayo Clinic. We’ll discuss the current regenerative products and therapies available to optimize patient outcomes, potential adverse effects of the therapies and the numerous claims by many clinicians regarding the benefit potential for regenerative medicine in musculoskeletal disease.  Specific topics discussed: Challenges of currently available traditional treatment for musculoskeletal conditions Benefits of stem cell injections for osteoarthritis Potential adverse effects of stem cell injections Currently available regenerative medicine therapies that have shown benefit to patients Validity of the many claims made by clinicians regarding the benefits of stem cell injections  Additional educational opportunities from Mayo Clinic:  https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Tyler S. Oesterle, M.D., M.P.H. (@OesterleMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Opioid abuse remains a significant problem, and as law enforcement and regulatory agencies tighten access to prescription analgesics, individuals are seeking alternatives. It’s been discovered that when taken at very high doses, loperamide can produce similar effects to the opioid analgesics and the drug is inexpensive when compared to the price of both illicit and prescription opioids. As a result, loperamide abuse has become a significant problem. In this episode we discuss loperamide abuse with Tyler Oesterle, M.D., M.P.H., a psychiatrist at Mayo Clinic’s Rochester campus. We’ll review the typical central nervous system effects of high dose loperamide and the associated safety issues. Specific topics: Current status of the opioid crisis in the U.S. Effects of loperamide in both therapeutic and excessive doses Reasons behind taking high dose loperamide in excessive doses Safety issues associated with high dose loperamide Potential of high dose loperamide leading to drug dependence Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

This episode is shared from Mayo Clinic Q&A and was recorded May 24, 2021. To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    The number of COVID-19 cases, hospitalizations and deaths in the U.S. continues to decline. However, cases of COVID-19 are increasing in younger populations.  "It's becoming a childhood disease," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Children have composed over 16,000 hospitalizations for COVID-19 and about 300 have died." Meanwhile, each day brings fresh research news, including updates on possible side effects of the COVID-19 vaccines.  "We're collecting information as we go and have data on about 4.5 million people now," says Dr. Poland. "That's larger than we would have for any other vaccine."  In this Mayo Clinic Q&A podcast, Dr. Poland expands on these latest news items and puts the data in perspective. He also discusses vaccination rates, the possibility of mixing and matching vaccines for COVID-19 boosters, vaccination rates, and much more. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline Guest: Saranya Wyles, M.D. (@SWylesMDPhD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) Much of regenerative medicine is relatively new and some of the future treatment capabilities have the potential to significantly change the way we practice medicine. How do you educate established clinicians as well as clinicians in training regarding this new practice? How do you educate the general public which has been misled by a variety of false claims regarding which medical conditions regenerative medicine can currently effectively treat? This podcast discusses how a relatively new medical field puts together an education program to inform others of its potential. Our guest is Saranya Wyles, M.D., a resident in the Department of Dermatology who has considerable experience in regenerative medicine education.  Specific topics discussed: Specific groups who need educating regarding the capabilities of regenerative medicine The importance in training the medical workforce regarding regenerative medicine What regenerative medicine means for the next generation of healthcare providers How to incorporate regenerative medicine concepts into an established medical school curriculum How to educate more advanced learn years such as residents and healthcare providers Obtaining an advanced degree in the field a regenerative medicine Additional resources: International Society for Stem Cell Research (ISSCR): https://www.isscr.org/ The ISSCR Patient Handbook on Stem Cell Therapies: https://www.closerlookatstemcells.org/patient-resources/ Regenerative medicine curriculum for next-generation physicians: https://www.nature.com/articles/s41536-019-0065-8 Digital regenerative medicine and surgery pedagogy for virtual learning in the time of COVID-19: https://www.futuremedicine.com/doi/full/10.2217/rme-2020-0106 Additional educational opportunities from Mayo Clinic: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

This episode is shared from Mayo Clinic Q&A and was recorded in May, 2021 To claim credit visit: https://ce.mayo.edu/covid19podcast  Guest:  Gregory A. Poland, M.D. (@drgregpoland)  Host: Halena M. Gazelka, M.D. (@hmgazelkamd)    Recent COVID-19 masking guidelines announced by the Centers for Disease Control and Prevention, continue to generate a public conversation. "The decision about masking needs to be nuanced," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Wearing a mask should be based on the risk of infection, the percentage of the population vaccinated, a person's own immune system, and then the role of vaccine variants with the durability of our immune response." In this Mayo Clinic Q&A podcast, Dr. Poland discusses masking guidelines in further detail. Also, he offers an update on COVID-19 vaccine research for children, and he shares positive news about the decreasing numbers of COVID-19 cases and deaths. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Carrie A. Thompson, M.D. (@CaThompsonMD) Host: Darryl S. Chutka, M.D. (@ChutkaMD) It’s common for a patient to see their primary care provider after they’ve discovered an enlarged lymph node and they’re usually concerned that it represents a serious illness. Fortunately, in most cases it’s due to a benign cause and most patients can be reassured once we perform a careful history and physical examination. However, on occasion lymphadenopathy can represent serious disease. Carrie Thompson, M.D. a hematologist, at Mayo Clinic’s Rochester campus joins us to discuss how to tell when lymphadenopathy is due to a benign or serious cause. We’ll review the characteristics of both benign and malignant lymph nodes and the evaluation which should be done both for an enlarged solitary lymph node as well as generalized lymphadenopathy. Specific topics discussed: Prevalence of malignancy in patients who seek a medical evaluation for lymphadenopathy Categories of disease which can have associated lymphadenopathy Characteristics of benign and malignant lymph nodes Diagnostic approach for a solitary enlarged lymph node Diagnostic approach or multiple or generalized lymphadenopathy Fine needle aspirate vs. excisional biopsy for evaluation of lymphadenopathy Additional resources: Gaddey, HL. Riegel, AM. Unexplained lymphadenopathy: evaluation and differential diagnosis. Am Fam Physician.2016 December 1; 94(11): 896-903. https://www.aafp.org/afp/2016/1201/p896.html Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.