The Proof with Simon Hill

In Episode #222, I’m joined by Drew Harrisberg and Kieron Rooney, PhD to discuss how the biochemistry of exercise can impact your health. We cover a wide range of topics, including mitochondria efficiency, metabolic flexibility, and fat adaptation. Dr Rooney also offers training advice, and his thoughts on a ketogenic diet.Evidence continuously shows us that the multitude of factors contributing to health and longevity are incredibly complex. Today, Kieran Rooney, PhD sits down with Drew Harrisberg and me to break down the biochemistry behind exercise, exploring both the theory and practical applications of improving your fitness.Specifically, we cover: Intro (0:00) Rodent Studies on Sucrose (5:40) Biochemistry of Exercise (22:28) Creatine Supplementation for Athletes (37:19) Do you need meat for creatine? (42:40) How Our Bodies Produce ATP (44:41) Defining Mitochondria (58:43) Increasing Efficiency (1:03:56) Omega 6s: Essential or Problematic? (1:06:00) Metabolic Flexibility (1:15:20) Make more Mitochondria (1:18:08) Mitochondria & Longevity (1:29:00) Lactate Levels (1:35:14) Best Training Advice (1:50:16) HIIT vs Endurance (2:01:10) Can Keto Work Long-Term? (2:12:42) Outro (2:45:15) To connect with Drew Harrisberg, you can find him on Instagram and visit his website, Drew’s Daily Dose. Kieron Rooney, PhD is active on Twitter, and you can learn more about him and his work here.The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.Enjoy, friends.SimonWant to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.Simon Hill, Msc, Bsc (Hons)Creator of Theproof.com and host of The Proof with Simon HillAuthor of The Proof is in the PlantsWatch the episodes on YouTube, or Listen on Apple/SpotifyConnect with me on Instagram, Twitter and FacebookDownload my complimentary two week meal plan and high protein plant performance recipe book

In Episode #221, I sit down with Dr Satchin Panda to continue The Proof’s conversation on time restricted eating. We discuss circadian rhythms, circadian disruption, and health impacts. We also cover TRE in the context of circadian biology, blood glucose, and calorie restriction. Dr Panda offers his advice on the optimal TRE lifestyle.Time-restricted eating (TRE) has caused a stir on social media in recent years. Many studies on TRE are misrepresented online, with people drawing absolute conclusions that often don’t consider all the data. Dr Panda joins me in this episode to look further into TRE, with a focus on circadian rhythm.Specifically, we cover: Intro (0:00) Circadian Rhythms (2:20) Why Circadian Disruption is a Problem (9:35) Dr. Panda’s Early Research (15:29) What Causes Sleep Deprivation (21:05) Disease & Circadian Disruption (26:07) Light Exposure (28:59) Time Restricted Eating (35:19) Optimal Eating Window (43:57) Impact on Blood Glucose (57:51) TRE vs Calorie Restriction (1:03:35) Addressing Concerns (1:24:12) Is Fasting Safe for Everyone? (1:26:52) Extended Fasts (1:35:35) Big Picture (1:39:00) Outro (1:43:14) To connect with Dr Satchin Panda, you can find him on Twitter and read his peer reviewed papers on Google Scholar. To learn more about circadian biology, his books, The Circadian Code and The Circadian Diabetes Code, are an incredible resource. You can also better understand your circadian rhythm while contributing to research with Dr Panda’s app, myCircadianClock.The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.Enjoy, friends.SimonWant to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.Simon Hill, Msc, Bsc (Hons)Creator of Theproof.com and host of The Proof with Simon HillAuthor of The Proof is in the PlantsWatch the episodes on YouTube, or Listen on Apple/SpotifyConnect with me on Instagram, Twitter and FacebookDownload my complimentary two week meal plan and high protein plant performance recipe book

In Episode #220, Dr MeiLan Han joins me to discuss the lungs and respiratory system.Despite being an incredibly important factor of our overall health, the respiratory system is often overlooked. Most people’s knowledge is surface level, and we aren’t educated on the importance of the lungs or how to best support respiratory health. Dr MeiLan Han joins me in this episode to explain what the respiratory system is, how it works, and what we can do to optimise it.In this episode, Dr Han establishes what the respiratory system is and how it works. We discuss the prevalence of lung conditions, Covid-19 and its impact on the respiratory system, and air quality. We also discuss healthy habits for pregnancy, the effects of smoking and vaping on lung health, diet, and how to reduce exposure to toxic compounds.Specifically, we cover: Intro (0:00) Breathing Lessons: The Book (2:09) Meilan’s Story (5:59) Importance of Lung Awareness (11:07) Lung Tests (24:25) Impact of Covid (29:57) How the Lungs Work (33:32) Childhood Lung Health (44:52) Air Quality (53:55) Cleansing the Lungs (1:15:20) COPD (1:19:47) Final Thoughts (1:27:32) Outro (1:29:35) If you are interested in learning more about lung health, Dr Han’s book is the perfect resource. You can find her book, Breathing Lessons: A Doctor’s Guide to Lung Health, here. You can also connect with Dr Han on Instagram, Twitter, Facebook, YouTube, and LinkedIn. Her website, www.drmeilanhan.com/, contains more information and trusted resources.The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.Make sure to head to theproof.com/podcast for the full show notes.Enjoy, friends.SimonWant to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. Simon Hill, Msc, Bsc (Hons) Creator of Theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube, or Listen on Apple/Spotify Connect with me on Instagram, Twitter and Facebook Download my complimentary two week meal plan and plant performance

In Episode #219, I sit down with Layne Norton, PhD to answer one very topical question: does insulin make us fat?Welcome to the first bite-sized episode of The Proof. In these short conversations, I am joined by a guest to tackle a single topic in a brief, digestible time frame. In this episode, Layne Norton, PhD addresses recent online claims by Ben Bikman, PhD. Dr Bikman claims that if we keep insulin low and control seed oils, fat cells can stay smaller and healthier. But is there any truth to this claim, and would that necessarily be a good thing?In this episode, Dr Norton takes a highly scientific approach to the topic at hand. We discuss adipocyte hypertrophy, the difference between and significance of hypertrophy versus hyperplasia, and the consequences of misinformation. We also examine the uses and drawbacks of mechanistic data.Specifically, we cover: Intro (0:00) Dr. Bikman’s Claims (2:24) Hyperplasia and hypertrophy (7:19) Gap of Research (12:17) Why this is problematic (15:56) Motives (20:14) Outro (22:53) To connect with Layne Norton, PhD, you can find him on Instagram and Twitter @biolayne, and on Facebook as Layne Norton. You can also visit his website, https://biolayne.com/, to learn more about his work and other resources.The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.Enjoy, friends.SimonWant to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.Simon Hill, Msc, Bsc (Hons)Creator of Theproof.com and host of The Proof with Simon HillAuthor of The Proof is in the PlantsWatch the episodes on YouTube, or Listen on Apple/SpotifyConnect with me on Instagram, Twitter and FacebookDownload my complimentary two week meal plan and high protein plant performance recipe book

In Episode #218, I’m joined by entrepreneur Arturo Elizondo to discuss the future of egg production.Ground-breaking changes are happening in our food industry every single day. While animal agriculture continues to grow, there is an increasing field of innovation seeking sustainable, ethical alternatives to the foods most people consume daily. Arturo Elizondo joins me today to pull back the curtain on one such initiative, The EVERY Co., revealing his journey and where this technology will take us.Think real eggs, just made differently.In this episode, we continue The Proof’s investigation into the future of animal-free proteins. Arturo expands on previous episodes, discussing the triumphs and challenges of current technologies in this space, the journey of The EVERY Co., and where the industry is heading. We also discuss food equity and availability, government regulations and funding, environmental considerations, concerns about genetic modification, and much more.Specifically, we cover: Intro (0:00) Day in the Life of Arturo (2:19) What Inspired a Chickenless Egg (13:10) Existing Products with Animal Protein (47:22) How precision fermentation works (55:55) Environmental Impact (1:14:40) Government & Industry Approval (1:18:25) Hybrid Products (1:29:04) Advice for Entrepreneurs (1:33:33) Vision for the Future (1:41:34) Outro (1:43:19) To connect with Arturo Elizondo, you can find him on LinkedIn and Twitter. You can discover more information about The EVERY CO. on their website, https://theeverycompany.com/.The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.Make sure to head to theproof.com/podcast for the full show notes.Enjoy, friends.SimonWant to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. Simon Hill, Msc, Bsc (Hons) Creator of Theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube, or Listen on Apple/Spotify Connect with me on Instagram, Twitter and Facebook Download my complimentary two week meal plan and plant performance

In Episode #217, I sit down with dietician Ginny Messina to address common nutrition myths about the vegan diet.With an abundance of nutrition “information” presented to us any time we use social media, it becomes difficult to identify whether a claim is fact or fiction. Misinformation is a common issue across all patterns of eating — including a plant-based diet — and understanding the full picture is incredibly important to ensure health and longevity. Ginny Messina, MPH, RD joins me to address common nutrition myths about the vegan diet, providing a broader view that will help plant-based eaters make sense of nutrition needs.In this episode, we address 16 myths that could have negative health implications if followed. Ginny Messina speaks to the limitations and strengths of the evidence that we have, provides recommendations for optimal health, and discusses the ethical reasons for making diet choices. We also cover supplementation, concerns about vegan diets, and how to evaluate claims you find online.Specifically, we discuss: Intro (0:00) Becoming Vegan (3:13) Risks of Vegan Misinformation (10:16) Whole Food Diets (20:36) Are Humans Herbivores? (22:55) Protein Myth (25:42) Processed Vegan Food (28:05) Calcium Needs (30:07) Dairy: Cancer & Addiction (33:40) Seafood & Mercury (39:34) Low Fat (44:18) Whole Foods vs Processed (51:47) Oil-Free (59:01) Raw Foods Diet (1:04:30) Vitamin B12 (1:08:35) Supplementing (1:23:16) Medication & Statins (1:31:38) Industry Funded Research (1:34:36) Greatest Risk to Vegans (1:39:40) Outro (1:43:55) To connect with Ginny, you can find her on Twitter, Instagram, and Facebook. You can also access her website, https://www.theveganrd.com/, and read her blog post on top vegan resources here. Make sure to check out her books — specifically her latest, updated book, Vegan for Life.Make sure to head to theproof.com/podcast for the full show notes.Enjoy, friends.SimonWant to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. Simon Hill, Msc, Bsc (Hons) Creator of Theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube, or Listen on Apple/Spotify Connect with me on Instagram, Twitter and Facebook Download my complimentary two week meal plan and plant performance

In Episode #216, I sit down with Dr David Jenkins to discuss the relationship between cholesterol and health.Cholesterol levels are concerningly high among populations consuming a standard Western diet. On the flip side, plant-based diets are often criticised for their lack of cholesterol. We know that cholesterol is an essential component of the human body — but is it necessary to consume it, and is this a concern for plant-based eaters? Dr David Jenkins answers this question and much more in today’s episode.In this episode, we dig into cholesterol and the health implications of sub-optimal levels. We discuss the Portfolio Diet, weight loss, and the current research on cholesterol. Dr Jenkins also shares his recommendations on how and what to eat for optimal cholesterol levels, as well as how medication compares to a lifestyle approach.Specifically, we cover: Intro (0:00) Researching Cholesterol & Diet (2:35) What this means for you (15:00) Weight Loss Factor (17:23) The Portfolio Diet Explained (20:14) Nuts & Seeds (30:37) Weight (39:45) Raising HDL (44:45) Plant Sterols (50:51) Should We Eat Fish? (58:52) Statins (1:07:49) Outro (1:11:22) You can learn more about Dr Jenkins and discover his publications on his University of Toronto profile. To view or purchase his daughter’s book, The Portfolio Diet for Cardiovascular Disease Risk Reduction, you can do so here.The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.Make sure to head to theproof.com/podcast for the full show notes.Enjoy, friends.SimonWant to support the show?If you are enjoying The Proof a great way to support the show is by leaving a review on the Apple Podcasts or a comment on YouTube. It only takes a few minutes and helps more people find the episodes. Simon Hill, Msc, Bsc (Hons) Creator of Theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube, or Listen on Apple/Spotify Connect with me on Instagram, Twitter and Facebook Download my complimentary two week meal plan and plant performance

In Episode #215, I’m joined by Dr Richard Johnson to discuss obesity, fructose, and metabolic disease.“Fructose” has become something of a fear word in modern diet culture. It is often positioned as the villain, without the in-depth breakdown of where we are sourcing this fructose and the quantities it is consumed in. Similarly, the relationship between health and obesity is hotly contested. Dr Richard Johnson sits down with me today to clarify the scientific relationship between these factors, getting into what the evidence tells us.In this episode, we take a broader view at the history of obesity before honing in on the biology and mechanisms. We discuss the ideology of obesity, whether you can be healthy at any size, and the degree of risk related to where you store fat. We also cover a variety of animal studies, sources of fructose, and how the modern food environment shapes our body weight.Specifically, we discuss: Intro (0:00) History of Obesity (2:30) Body Fat & Health Span (10:36) Causes & Behavioral Patterns (23:55) Fructose vs Excess Calories (38:18) The Hazda (1:03:50) Fructose & Fruit (1:11:10) Fruitarians (1:22:25) Not All Carbs are the Same (1:32:30) Purines & Uric Acid (1:39:55) Carnivore Diet (1:42:22) Summarizing Obesity (1:53:56) Outro (2:02:46) To connect with Dr Richard Johnson, you can find him on Instagram and Twitter. You can also learn more at his website, https://drrichardjohnson.com/. His latest book, Nature Wants Us To Be Fat, is now available.The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.Make sure to head to theproof.com/podcast for the full show notes.Enjoy, friends.SimonWant to support the show?If you are enjoying The Proof a great way to support the show is by leaving a review on the Apple Podcasts or a comment on YouTube. It only takes a few minutes and helps more people find the episodes. Simon Hill, Msc, Bsc (Hons) Creator of Theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube, or Listen on Apple/Spotify Connect with me on Instagram, Twitter and Facebook Download my complimentary two week meal plan and plant performance

In Episode #214, I sit down with Josh Tetrick to discuss reshaping our food system towards plant-based products and slaughter-free meat alternatives.As animal-free proteins grow in popularity, technologies for creating them are too. Josh Tetrick wants to reshape our food system, and joins me today to share his journey with Eat Just. Josh is committed to facilitating innovation in the plant-based sphere and offers valuable insight into emerging technologies in today’s episode.In this episode, we discuss business as a force for change and the future of the animal-free industry. Josh shares some of his story, explaining where he found the drive to act and how he raised more than half a billion dollars. We look deeper into Eat Just’s products, specifically their very successful “Just Egg”. We also discuss the nutritional profile of cultivated meat and other plant-based alternatives; challenges Josh has overcome; and the benefits of alternative products.Specifically, we cover: Intro (0:00) Josh’s Story (2:20) Having the Courage to Act (9:51) Evaluating the Meat Industry (20:12) The Mission of JUST (29:10) Negative Press & The Egg Industry (47:27) Cultivated Meat (1:10:30) Challenges & Pushback (1:36:24) Nutritional Profile (1:44:58) Skeptics & Timeline (1:48:32) Outro (2:05:47) To connect with Josh, you can find him on Twitter or send him an email. You can also learn more about Eat Just at their website, and discover the future of cultivated meats at the Good Meat website.Thank you to The Proof friend Eimele Essential 8 for sponsoring today’s episode. Eimele Essential 8 offers the right nutrients, in the right doses, to complement a plant-rich diet. To save 5% on your first order, head to theproof.com/friends.Make sure to head to theproof.com/podcast for the full show notes.Enjoy, friends.SimonWant to support the show?If you are enjoying The Proof a great way to support the show is by leaving a review on the Apple Podcasts or a comment on YouTube. It only takes a few minutes and helps more people find the episodes. Simon Hill, Msc, Bsc (Hons) Creator of Theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube, or Listen on Apple/Spotify Connect with me on Instagram, Twitter and Facebook Download my complimentary two week meal plan and plant performance

In Episode #213, Dr Jenna Macciochi joins me for a deep dive into the human immune system.“Immunity” has become a buzzword in health spheres at the moment. From supplement marketing to recipe promotion, there seem to be countless quick-fix products or ingredients to “boost” and improve the immune system. But is there any validity to these claims? Dr Jenna Macciochi joins me today to look deeper into what actually creates a balanced immune system.In this episode, we cover broader explanations of what the immune system is and what it does before getting into the finer details. Dr Macciochi also provides an abundance of applicable information, explaining the mechanisms behind what impacts the immune system. We discuss the extent of control we have over our own immune system, indications of a disrupted immune system, and the importance of gut health. Dr Macciochi also shares insight into vaccines, inflammation, diet, and supplementation.Specifically, we cover: Intro (0:00) Becoming an Immunologist (5:38) Explaining the Immune System (9:00) Impact of Genetics (15:05) Immunity & Immune-Washing (19:07) Reaction to Virus’ (28:04) Pregnancy & Childhood (31:00) Understanding Your Immunity (44:53) Bacterial VS Viral Infections (56:00) Antibiotics (58:48) Germ vs Terrain Theory (1:04:36) Natural Immunity (1:09:23) Inflammation Explained (1:18:38) Anti-Inflammatory Diets (1:29:28) Phytonutrients & Toxic Plants (1:44:31) Eat the Rainbow (1:57:52) Beta-Glucans (2:05:40) Animal Foods (2:07:37) Healthy Fats (2:12:48) Supplementing Vitamins (2:16:04) Outro (2:32:10) To connect with Dr Jenna Macciochi, you can do so on Instagram, Twitter, and her website. Make sure to check out her first book Immunity: The Science of Staying Well. Her new book, Your Blueprint for Strong Immunity, is now available as well.Thank you to The Proof friend Eimele Essential 8 for sponsoring today’s episode. Eimele Essential 8 offers the right nutrients, in the right doses, to complement a plant-rich diet. To save 5% on your first order, head to theproof.com/friends.Make sure to head to theproof.com/podcast for the full show notes.Enjoy, friends.SimonWant to support the show?If you are enjoying The Proof a great way to support the show is by leaving a review on the Apple Podcasts or a comment on YouTube. It only takes a few minutes and helps more people find the episodes.Simon Hill, Msc, Bsc (Hons) Creator of Theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube, or Listen on Apple/Spotify Connect with me on Instagram, Twitter and Facebook Download my complimentary two week meal plan and plant performance