Working Intelligence: Making Americans Irreplaceable
AI Optimists
Real stories from real people using AI to transform their work and communities for the better.
Each episode showcases the human side of artificial intelligence—from nurses personalizing patient care and entrepreneurs scaling their businesses, to creators pushing new boundaries. These are the voices of everyday innovators who are building a smarter, more connected world.
Hosted by the AI Optimists of Palantir, Working Intelligence celebrates the Americans harnessing AI's power to solve problems, create opportunities, and improve communities across the country.
Each episode showcases the human side of artificial intelligence—from nurses personalizing patient care and entrepreneurs scaling their businesses, to creators pushing new boundaries. These are the voices of everyday innovators who are building a smarter, more connected world.
Hosted by the AI Optimists of Palantir, Working Intelligence celebrates the Americans harnessing AI's power to solve problems, create opportunities, and improve communities across the country.
Episodes
Mentioned books
Oct 21, 2025 • 42min
Unlocking Health: AI's Transformation of Medicine and Science, with Jamie Metzl
We're standing at the threshold of a medical revolution that will reshape how we diagnose, treat, and prevent disease. In this episode of Working Intelligence: Making Americans Irreplaceable, healthcare futurist and geopolitical expert Jamie Metzl explains why the Superconvergence of AI and biotechnology—the subject of his new book, out today—represents one of the most transformative breakthroughs in the history of medicine.Join Sophie Singletary and Jamie Metzl as they explore how AI is already accelerating drug discovery, enabling personalized medicine tailored to individual genetic profiles, supercharging economies, and expanding our understanding of human biology. Metzl reveals why this convergence of technologies will extend human healthspan, make cutting-edge treatments accessible to billions, and unlock medical innovations we can hardly imagine today.This is a conversation about the extraordinary promise of AI-driven healthcare, the critical choices we face in ensuring these breakthroughs benefit everyone, and why we're living through the most hopeful moment in the history of medicine.
10 snips
Sep 11, 2025 • 38min
From 9/11 to AI: Mike Gallagher on How American Workers Will Win the 21st Century
Mike Gallagher, a former Marine Corps intelligence officer and Congressman now at Palantir, shares his insights on resilience and innovation in America. He discusses how the aftermath of 9/11 transformed national strategy and parallels it with today’s AI-driven technological race against China. Gallagher passionately argues that AI should enhance rather than replace American workers, showcasing real-life examples of AI's positive impact in shipyards and agriculture. His optimistic vision for the future emphasizes the crucial role of human ingenuity augmented by technology.
23 snips
Sep 1, 2025 • 18min
How AI Will End 50 Years of Economic Stagnation, with Tyler Cowen
Tyler Cowen, a prominent economist and director of the Mercatus Center, discusses the transformative power of AI in revitalizing the economy after decades of stagnation. He argues that AI will democratize access to services like healthcare and legal expertise while fostering new ventures and job creation. The conversation explores how America's robust markets and innovative culture are primed for an AI-led revolution. Cowen also highlights AI's potential social impacts, from enhancing personal learning to changing our concepts of companionship.
