
Working Intelligence: Making Americans Irreplaceable Unlocking Health: AI's Transformation of Medicine and Science, with Jamie Metzl
Oct 21, 2025
In this thought-provoking discussion, Jamie Metzl, a technology and healthcare futurist, reveals how AI is transforming medicine and biotechnology. He shares personal insights from his father's cancer treatment, showcasing the power of genomic sequencing. The conversation delves into AI's rapid advancements, the shift toward personalized medicine, and how these technologies can expand our understanding of biology. Metzl underscores the importance of ethics and governance in ensuring these innovations benefit everyone, making this a hopeful moment in healthcare.
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Superconvergence Is Civilizational
- AI and biotech form a Superconvergence that can reshape civilization quickly and broadly.
- Jamie Metzl argues we must pair technical progress with values, governance, and public engagement.
Include The Public Early
- Bring everyone into conversations about AI and biotech to reduce fear and shape better outcomes.
- Engage citizens through books, podcasts, and public debate to align values with technological choices.
AI's Pace Makes It Different
- AI's rate of improvement makes it distinct from past technologies and enables rapid empowerment of humans and machines.
- Metzl rejects AGI as a concept but recognizes machine superintelligence will augment human capabilities.





