Longevity by Design
Gil Blander PhD
Longevity by Design is your go-to podcast for unlocking the secrets to a longer, healthier life. Hosted by Dr. Gil Blander, a renowned scientist and entrepreneur in the fields of aging, nutrition, and personalized health, this show dives into cutting-edge research and practical strategies for optimizing your healthspan and lifespan.In each episode, Dr. Blander sits down with leading longevity and health scientists to explore how we can live better, longer lives. From unpacking complex scientific concepts to sharing the latest advancements in aging research, Longevity by Design offers science-backed insights and actionable advice to help you add years to your life—and life to your years.Dr. Blander is the founder and Chief Scientific Officer of InsideTracker, a healthspan company that leverages blood tests, DNA analysis, fitness tracker data, and other biomarkers to deliver personalized health recommendations. With a Ph.D. in biology from the Weizmann Institute of Science and postdoctoral research at MIT, Dr. Blander brings decades of expertise and passion to every conversation.Tune in to Longevity by Design and discover how to live a longer, healthier, and more vibrant life.
Episodes
Mentioned books
May 6, 2022 • 1h
Dr. Eric Verdin—The Effect of Food on Longevity
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Eric Verdin, the President and Chief Executive Officer of the Buck Institute for Research on Aging. Tune in as Dr. Eric Verdin discusses nutrient sensing, epigenetic regulation, and recent research on the impact of foods on longevity. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Apr 20, 2022 • 39min
Dr. Ali Torkamani—Genomics and Aging
Your genetics can uncover many things about you. They can influence how you look and behave, to name a few. But your genes are not deterministic; they don't tell your entire story.In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Ali Torkamani, Director of Genome Informatics at the Scripps Research Translational Institute. Tune in as Dr. Ali Torkamani discusses how genetics impact lifespan and healthspan, why genetics aren't deterministic, and how lifestyle factors promote a healthier, longer life.To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Apr 6, 2022 • 41min
Dr. Eran Segal—The Value of Personalized Nutrition
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Eran Segal, Faculty Member at The Weizmann Institute of Science in Israel. Tune in as Dr. Eran Segal discusses the value of personalized nutrition, how data contributes to our knowledge of personalized food responses, and the relationship between food and longevity.To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Mar 25, 2022 • 1h 1min
Dr. Raul Mostoslavsky—SIRT 6 and the Hallmarks of Aging
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Raul Mostoslavsky, the Laurel Schwartz Professor of Oncology at Harvard Medical School. Dr. Raul Mostoslavsky has studied sirtuin functions in cancer for many years and has identified a pathway responsible for tumor growth in 30% to 40% of pancreatic cancer patients and more recently identified metabolism as a heterogeneous feature of cancer. Dr. Raul Mostoslavsky discusses the role of sirtuins in aging and explains how the mechanisms that protect us from cancer may also preserve our longevity on a cellular level.To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Mar 9, 2022 • 47min
Dr. Steven Austad—A Unique Perspective to Aging Research
In this episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Steven Austad, Professor and Protective Life Endowed Chair in Healthy Aging Research of the Department of Biology at the University of Alabama at Birmingham. Tune in as Dr. Steven Austad describes how his unique career path from lion tamer to aging researcher has influenced his perspective on the top questions in the field. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Feb 22, 2022 • 58min
Dr. Nir Barzilai—Genetics and Lifestyle Factors of Centenarians
Aging research is quickly evolving to understand how we can live healthier, longer lives. Scientists are looking to centenarians and their family members to reveal how their environment, lifestyle, and genetics contribute to their delayed aging.In this episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Nir Barzilai, Director of the Institute for Aging Research at the Albert Einstein College of Medicine. Tune in as Dr. Nir Barzilai describes how he pursued a career in aging, where the research stands on metformin and longevity, and the Longevity Genes Project, genome mapping 750 centenarians and their family members to understand the genetic component of aging.To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Feb 8, 2022 • 59min
Dr. Matt Kaeberlein—Novel Research on Longevity Agents in Domestic Dogs
Recent studies highlight the role of specific longevity agents like rapamycin in slowing the aging process in animal models. Namely, scientists believe that rapamycin, proper nutrition, and caloric restriction may slow down the aging process in animal models and may be transferable to human health.In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Matt Kaeberlein, Professor at the Department of Laboratory Medicine and Pathology at the University of Washington. Tune in as Dr. Matt Kaeberlein describes the longevity agent rapamycin and its impact on mTOR and the Dog Aging Project, which is investigating companion dogs as a model organism for aging.To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Jan 31, 2022 • 46min
Dr. Heidi Tissenbaum–Lessons From C. Elegans to Increase Healthspan
In recent years, aging research has shifted its focus from lifespan to healthspan to understand the processes that define aging. Dr. Heidi Tissenbaum’s research investigates the fundamental pathways and genes that determine how we age. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Heidi Tissenbaum, professor at the University of Massachusetts Medical School. Tune in as Dr. Heidi Tissenbaum distinguishes between lifespan and healthspan, how she uses C. Elegans as a model organism for aging, and how added dietary sugars can interfere with longevity. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Jan 12, 2022 • 43min
Dr. Haim Cohen — The Protective Role of SIRT6 on Aging and Longevity
One topic that Longevity by Design guests can agree on is that sirtuin-6 (SIRT6) plays a protective role in aging and age-related conditions. Dr. Haim Cohen’s lab researches sirtuins, a class of enzymes involved in longevity and aging. He’s specifically interested in SIRT6 and its protective role in the aging process, as well as age-related conditions like cancer, insulin resistance, inflammation, and metabolic health.In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Haim Cohen, Director of the National Metabolic Center for Excellence in Scientific Research in Human Diseases, and professor at Bar-Ilan University. Tune in as Dr. Haim Cohen takes a deep dive into SIRT6 and how his groundbreaking discovery about this enzyme can contribute to what we know about the aging process. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Dec 8, 2021 • 1h 1min
Dr. Andrew Huberman — How The Gut Microbiome, Sleep, and Sunlight Impact The Brain
Inspired by the great unknowns of the brain, Dr. Andrew Huberman pursued neuroscience. From there, he realized that his passion also lay in the art of conveying scientific information in a way that scientists and non-scientists alike can understand. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Andrew Huberman. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at the Stanford University School of Medicine and host of the Huberman Labs Podcast.Tune in as Dr. Andrew Huberman takes a deep dive into how the gut microbiome, sleep, and sunlight impact the brain and how to hack your daily habits to live a healthier, longer life. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
