Longevity by Design
Gil Blander PhD
Longevity by Design is your go-to podcast for unlocking the secrets to a longer, healthier life. Hosted by Dr. Gil Blander, a renowned scientist and entrepreneur in the fields of aging, nutrition, and personalized health, this show dives into cutting-edge research and practical strategies for optimizing your healthspan and lifespan.In each episode, Dr. Blander sits down with leading longevity and health scientists to explore how we can live better, longer lives. From unpacking complex scientific concepts to sharing the latest advancements in aging research, Longevity by Design offers science-backed insights and actionable advice to help you add years to your life—and life to your years.Dr. Blander is the founder and Chief Scientific Officer of InsideTracker, a healthspan company that leverages blood tests, DNA analysis, fitness tracker data, and other biomarkers to deliver personalized health recommendations. With a Ph.D. in biology from the Weizmann Institute of Science and postdoctoral research at MIT, Dr. Blander brings decades of expertise and passion to every conversation.Tune in to Longevity by Design and discover how to live a longer, healthier, and more vibrant life.
Episodes
Mentioned books
Mar 9, 2022 • 47min
Dr. Steven Austad—A Unique Perspective to Aging Research
In this episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Steven Austad, Professor and Protective Life Endowed Chair in Healthy Aging Research of the Department of Biology at the University of Alabama at Birmingham. Tune in as Dr. Steven Austad describes how his unique career path from lion tamer to aging researcher has influenced his perspective on the top questions in the field. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Feb 22, 2022 • 58min
Dr. Nir Barzilai—Genetics and Lifestyle Factors of Centenarians
Aging research is quickly evolving to understand how we can live healthier, longer lives. Scientists are looking to centenarians and their family members to reveal how their environment, lifestyle, and genetics contribute to their delayed aging.In this episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Nir Barzilai, Director of the Institute for Aging Research at the Albert Einstein College of Medicine. Tune in as Dr. Nir Barzilai describes how he pursued a career in aging, where the research stands on metformin and longevity, and the Longevity Genes Project, genome mapping 750 centenarians and their family members to understand the genetic component of aging.To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Feb 8, 2022 • 59min
Dr. Matt Kaeberlein—Novel Research on Longevity Agents in Domestic Dogs
Recent studies highlight the role of specific longevity agents like rapamycin in slowing the aging process in animal models. Namely, scientists believe that rapamycin, proper nutrition, and caloric restriction may slow down the aging process in animal models and may be transferable to human health.In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Matt Kaeberlein, Professor at the Department of Laboratory Medicine and Pathology at the University of Washington. Tune in as Dr. Matt Kaeberlein describes the longevity agent rapamycin and its impact on mTOR and the Dog Aging Project, which is investigating companion dogs as a model organism for aging.To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Jan 31, 2022 • 46min
Dr. Heidi Tissenbaum–Lessons From C. Elegans to Increase Healthspan
In recent years, aging research has shifted its focus from lifespan to healthspan to understand the processes that define aging. Dr. Heidi Tissenbaum’s research investigates the fundamental pathways and genes that determine how we age. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Heidi Tissenbaum, professor at the University of Massachusetts Medical School. Tune in as Dr. Heidi Tissenbaum distinguishes between lifespan and healthspan, how she uses C. Elegans as a model organism for aging, and how added dietary sugars can interfere with longevity. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Jan 12, 2022 • 43min
Dr. Haim Cohen — The Protective Role of SIRT6 on Aging and Longevity
One topic that Longevity by Design guests can agree on is that sirtuin-6 (SIRT6) plays a protective role in aging and age-related conditions. Dr. Haim Cohen’s lab researches sirtuins, a class of enzymes involved in longevity and aging. He’s specifically interested in SIRT6 and its protective role in the aging process, as well as age-related conditions like cancer, insulin resistance, inflammation, and metabolic health.In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Haim Cohen, Director of the National Metabolic Center for Excellence in Scientific Research in Human Diseases, and professor at Bar-Ilan University. Tune in as Dr. Haim Cohen takes a deep dive into SIRT6 and how his groundbreaking discovery about this enzyme can contribute to what we know about the aging process. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Dec 8, 2021 • 1h 1min
Dr. Andrew Huberman — How The Gut Microbiome, Sleep, and Sunlight Impact The Brain
Inspired by the great unknowns of the brain, Dr. Andrew Huberman pursued neuroscience. From there, he realized that his passion also lay in the art of conveying scientific information in a way that scientists and non-scientists alike can understand. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Andrew Huberman. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at the Stanford University School of Medicine and host of the Huberman Labs Podcast.Tune in as Dr. Andrew Huberman takes a deep dive into how the gut microbiome, sleep, and sunlight impact the brain and how to hack your daily habits to live a healthier, longer life. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
Nov 19, 2021 • 34min
Dr. Vera Gorbunova — Applying Lessons From Long-Living Animals to Combat Human Aging
Did you know that there are species of whales that can live to be over 200 years old? Or that naked mole rats can live up to ten times longer than other mice? These facts and more led scientist Dr. Vera Gorbunova to investigate the mechanisms behind long-lived species and how these can be applied to what we know about aging in humans. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Vera Gorbunova, Professor of Biology at the University of Rochester and co-director of the Rochester Aging Research Center. Tune in as Dr. Vera Gorbunova discusses commonalities between long-lived animals and how humans can apply these principles into their lives today. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
6 snips
Oct 30, 2021 • 40min
Dr. Brian Kennedy — How Simple Lifestyle Changes Can Slow Down the Aging Process
We can’t rely on the magical elixir of life to stay forever young and healthy, but we can change certain lifestyle habits associated with premature aging. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Brian Kennedy, Professor of Biochemistry and Physiology at the National University of Singapore, to discuss his approach to longevity and aging. Longevity is a complex matter, but Dr. Brian Kennedy explains its most vital details. Tune in to this episode to learn more about how food choices, supplements, exercise, and other lifestyle habits that we can control encourage longevity and prevent associated diseases. To learn more and download InsideTracker's InnerAge eBook, visit: insidetracker.com/podcast
Sep 30, 2021 • 53min
Dr. William Evans – Why Muscle Mass is a Marker of Longevity
Should the elderly engage in physical activity? How do nutrient needs change throughout the lifespan? Researchers and scientists worldwide strive to get revolutionary answers to top aging questions. Our guest is one of them. In this episode of the Longevity by Design podcast, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. William Evans, adjunct professor of Human Nutrition at the University of California, Berkeley. Dr. Evans was the first to describe sarcopenia, the age-related loss of muscle mass and strength. Additionally, Dr. William Evans’ research sheds light on the connection between sarcopenia and lower levels of biomarkers like testosterone, estrogen, growth hormone production, and increased insulin resistance.Tune in to this episode, as Dr. William Evans discusses his research on exercise in older adults, how protein requirements change during the lifespan, and how this contributes to aging as a whole. To learn more and download InsideTracker's InnerAge eBook, visit: insidetracker.com/podcast
Aug 18, 2021 • 38min
Dr. David Sinclair – A World-Renowned Scientist's View on Longevity and Health
Dr. David Sinclair is a world-renowned scientist with a rich background in genetics and longevity research. Dr. David Sinclair, Ph.D., A.O. is a geneticist at Harvard Medical School and a Co-founder and Co-chief editor of the journal Aging. He's an inventor on 35 patents and has received more than 35 awards and honors. We're proud to have him on our team as the Chairman of the InsideTracker Scientific Advisory Board. Is aging a disease or a natural process? How can we impact aging on a cellular level? What daily habits can you implement to improve your lifespan? How does intermittent fasting impact cell function and longevity? In this episode of the Longevity by Design podcast, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. David Sinclair to discuss his aging research, top tips for longevity, and interestingly, what it’s like to work in his lab.For an exclusive offer, visit: https://info.insidetracker.com/sinclair
