

Longevity by Design
Gil Blander PhD
Longevity by Design is your go-to podcast for unlocking the secrets to a longer, healthier life. Hosted by Dr. Gil Blander, a renowned scientist and entrepreneur in the fields of aging, nutrition, and personalized health, this show dives into cutting-edge research and practical strategies for optimizing your healthspan and lifespan.In each episode, Dr. Blander sits down with leading longevity and health scientists to explore how we can live better, longer lives. From unpacking complex scientific concepts to sharing the latest advancements in aging research, Longevity by Design offers science-backed insights and actionable advice to help you add years to your life—and life to your years.Dr. Blander is the founder and Chief Scientific Officer of InsideTracker, a healthspan company that leverages blood tests, DNA analysis, fitness tracker data, and other biomarkers to deliver personalized health recommendations. With a Ph.D. in biology from the Weizmann Institute of Science and postdoctoral research at MIT, Dr. Blander brings decades of expertise and passion to every conversation.Tune in to Longevity by Design and discover how to live a longer, healthier, and more vibrant life.
Episodes
Mentioned books

Mar 29, 2023 • 1h 38min
Dr. Kate Wolin—How To Use Behavioral Science To Build Healthy Habits
In this episode of Longevity by Design, Dr. Kate Wolin discusses the tactics of behavior change science that can promote sustainable healthy habits. As a behavioral epidemiologist, Dr. Wolin provides actionable advice for health promotion in many contexts. She explains the science of motivation and how leveraging one’s motivation can promote behavior change. She also dives into how our environment facilitates positive or negative health behaviors and how to alter them. Tune in to hear the latest science on behavior change and forming healthy habits. For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Mar 15, 2023 • 40min
Dr. Noah Davidsohn—Gene Therapies for Age-Related Diseases
This episode of Longevity by Design discusses groundbreaking research on the use of gene therapies to target common diseases of aging. Dr. Noah Davidsohn leverages genes associated with aging as targets for de-aging cells and reducing the burden of age-related diseases. The research appears promising—Dr. Davidsohn is confident that these findings will eventually improve human lifespan and healthspan. Tune in for conversations that dissect the latest research in the field of longevity. For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Feb 22, 2023 • 42min
Dr. Joan Mannick—mTOR's Role in Aging
During this episode of Longevity by Design, Dr. Joan Mannick explains how mTOR influences the aging process. She explains that this evolutionarily conserved protein is involved in several cellular functions in the body and acts on longevity-promoting pathways like autophagy. Dr. Mannick also discusses the connection between mTOR and the immune system, sharing her research on how low-dose mTOR inhibitors can upregulate antiviral immunity, creating an opportunity for more targeted vaccines for older adults. After extensive research on mTOR across many species, Dr. Mannick shares impressive insight into how mTOR inhibitors like rapamycin can promote longevity. Tune in to learn more about the latest research in the field. For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Feb 8, 2023 • 51min
Dr. Andrea Maier—Mechanisms of Aging
This episode of Longevity by Design discusses topics related to longevity medicine, including mechanisms of aging, biological aging clocks, organ-specific aging, and factors that impact healthspan. With impressive clinical and research experience, Dr. Maier explains the importance of integrating longevity medicine into general practice as well as the current state of diagnostic tools within the field. For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Jan 25, 2023 • 58min
Dr. Jennifer Garrison—Women's Health and Longevity Part 2
This episode of Longevity by Design is the second of a two-part series in which Dr. Jennifer Garrison discusses women's health and the menopausal transition. In this episode, Dr. Garrison talks about reproductive health, the hormonal fluctuations women experience during their life, and the health implications of menopause. For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Jan 11, 2023 • 50min
Dr. Jennifer Garrison—Women's Health and Longevity Part 1
This episode of Longevity by Design discusses concepts related to women's health, including the brain-ovary connection, reproductive health, ovarian aging, and the health implications of menopause. Our guest today is Dr. Garrison, a neuroscientist, and expert in reproductive health. Dr. Garrison talks about gender inequalities in research and how her research lab aims to progress the scientific understanding of women's health and longevity. For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

5 snips
Dec 7, 2022 • 49min
Dr. Marco Altini—Heart Rate Variability and the Stress Response
This episode of Longevity by Design is an in-depth discussion on heart rate variability (HRV) and the stress response. Our guest today is Dr. Altini, an HRV expert and data expert. He and Dr. Blander talk through the definition of HRV, how stress impacts the autonomic nervous system, and the many factors that influence HRV. Tune in as Dr. Altini sheds light on how to interpret and improve this highly individualized marker. For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Nov 16, 2022 • 56min
Dr. Alex Zhavoronkov + Deepankar Nayak—Biological Aging Clocks
This episode of Longevity by Design discusses the research behind biological aging clocks, artificial intelligence, and organ-specific aging with Dr. Alex Zhavoronkov and Deepankar Nayak.In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Alex Zhavoronkov and Deepankar Nayak. Dr. Zhavoronkov and Deepankar have extensive knowledge of biological aging clocks—how they are developed, what they measure, how to interpret them, and much more. Through valuable and ground-breaking science, they describe how artificial intelligence and biological aging clocks together shape how to view and optimize healthspan. Tune in as Dr. Zhavoronkov and Deepankar discuss the latest science in the field. For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Nov 2, 2022 • 41min
Dr. Jennifer Elisseeff—Regenerative Medicine and Immunology
This episode of Longevity by Design discusses topics related to regenerative medicine—senescent cells, biomaterials, arthritis, immunology, and more.In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Jennifer Elisseeff. Dr. Elisseeff holds a PhD in Medical Engineering and has conducted many interesting studies relating to tissue engineering and the immune system. Tune in as Dr. Elisseeff discusses the latest science in the field. For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Oct 19, 2022 • 47min
Dr. Evelyne Bischof—Applying Longevity Medicine to Optimize Healthspan
This episode of Longevity by Design is all about longevity medicine, diving deep into the topic of longevity clinics, practical tools for using longevity medicine, and how this approach to healthspan differs from traditional methods of care. In this episode of Longevity by Design, our host, Dr. Gil Blander, is joined by Dr. Evelyne Bischof, Chief Physician Associate of Internal Medicine at University Hospital Renji of Jiaotong University Shanghai and Concierge Longevity Physician for executive longevity patients. Tune in as Dr. Bischof, a healthspan enthusiast and practitioner, shares interesting and exciting information about the growing field of longevity medicine.For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast