
Life Optimized
Life isn’t measured by the number of years on the earth, but by the quality of life that you can pack in to those the years you have. That’s why it’s important to optimize your healing and dial in your health so that you can thrive. Join Dr. Neil Paulvin, a leading Functional Medicine Physician practicing in New York City, as he interviews experts in every aspect of physiological optimization. Whether you’re a biohacker, an athlete, or an entrepreneur looking to maximize your performance, Dr. Paulvin is here to help you thrive!
Latest episodes

Oct 10, 2022 • 48min
04: Biohacking Your Skincare with Amitay Eshel
Today’s episode focuses on biohacking in the skincare industry. Today’s guest shares how innovations in longevity, anti-aging, and health optimization translate into topical products. Join us to learn more!Amitay Eshel is the co-founder and CEO of Young Goose, a biohacking skincare company that uses skin regenerative therapy to correct cellular damage. He has worked with hair care and red light therapy before finding his place in the skincare field. As an Israeli military veteran, he had brain injuries that prompted his interest in biohacking, longevity, and NAD. Young Goose is on the cutting edge of new skincare biohacking innovations. Show Highlights:The role of NAD in the skin and the body’s regenerative processesWhat a patient can expect from using an NAD skin creamWhy Young Goose only puts NAD precursors in two of their productsWhy Young Goose’s sunscreen is different from most others on the marketHow even artificial light can damage the skin and cause pigmentationWhat to look for in a sunblock (and why you should avoid chemical sunblocks) if you are concerned about your healthWhat to consider in taking NAD suppositories, IVs, and creamsHow peptides are used in Young Goose productsHow hyperbaric technologies are used in skincareHow red light therapies can help with general health and specific skincare issues to help our cells function more optimallyResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Find out more about Young GooseWebsite, Instagram, Podcast

Sep 27, 2022 • 41min
03: How Spermidine Helps Reverse the Aging Process with Leslie Kenny
Today’s episode focuses on spermidine as a supplement with known benefits in cellular renewal, healthy aging, and beauty. Our expert guest explains what spermidine is, where it’s found, and how it can be used to combat the effects of aging. She explains the research and results from the Oxford Healthspan supplement, Primeadine, which is one that I recommend to all my patients. Join us to learn more!Leslie Kenny is an autoimmune disease survivor and certified health coach. She is the founder of Oxford Healthspan and the co-founder of the Oxford Longevity Project. They offer free public service webinars about breakthrough scientific discoveries that are being translated into new protocols that patients can use. Cellular renewal is of special interest to Leslie because of its effect on the aging process. She shares with us how our bodies manufacture and use spermidine, and why most people need a supplement for maximum health and anti-aging benefits. Show Highlights:Why spermidine is of particular use in cellular renewal How our bodies repair themselves through the production of spermidine Why spermidine is produced today in supplement form even though it’s present in some foodsThe relation between a healthy gut biome and spermidine productionThe hallmarks of aging and spermidine’s effects on osteoporosisWhy spermidine dosage should be personalized to each person’s preference Leslie’s theory about gluten-free spermidine supplements and the gut biome of each person’s maternal lineBenefits of spermidine, which are most notably healing of the gut lining and reducing inflammationHow Leslie has reversed her autoimmune illnesses through diet and supplementsHow spermidine helps in the autophagy process (cellular renewal and recycling), which diminishes as we ageHow spermidine assists in the growth of hair, skin, and nails–and has been linked to the reversal of gray hair!Who should take a spermidine supplement and when they should start taking itHow to get more spermidine through foodsResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Find out more: www.oxfordhealthspan.com, www.primeadine.com Find Primeadine on InstagramFind Oxford Healthspan on InstagramFor email support about Primeadine: support@oxfordhealthspan.com

Sep 26, 2022 • 48min
02: Biohacking and the Quantified Self Movement with Bob Troia
Welcome to Episode 2 of the podcast! New technologies can give us much detail about our bodies’ efficiency and function, but there are many questions. What technologies are most beneficial? Are there affordable options to use at home? How do we use the information to optimize health and wellness? Join us in today’s conversation to learn more!Bob Troia, aka “Quantified Bob,” is well known in the personal optimization space. Based in NYC, he is a technology entrepreneur and biohacker focused on the intersection of data-driven citizen science, health and wellness, human performance, and longevity. Bob has been at the forefront of digital innovation and emerging technology for two decades, and he is a prominent voice in the biohacking and quantified self movement. He addresses many present-day issues in the field in his blog, Quantified Self, which can be found on his Website. In addition to speaking at leading international conferences, Bob has appeared on numerous media outlets including CBS News Sunday Morning, PBS Newshour Weekend, National Geographic Explorer, CBC (Canada), SBS-TV (South Korea), Fast Company, Men’s Fitness, and Outside Magazine as well as many wellness-related podcasts. He is the co-founder of Awesome Labs, a health, wellness, and emerging technology studio. Show Highlights:How the biohacking movement has evolved over the last ten yearsHow biohacking has become a worldwide phenomenon that people use for various reasons to improve their health and wellnessWhat Bob sees as the current top emerging technologies in the fieldThe importance of doing research before you invest in new technologiesHow high-level athletes can use the available technologies to optimize performanceSimple biohacking modalities people can use without spending big moneyThe benefits of percussive devices and compression therapyNew technologies in electro-muscular therapy and brain-training toolsBob’s recommendations regarding supplements, injections, fasts, etc. What to look for in the near future in the field of quantified health ResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with BobWebsite, Instagram, TwitterFind out more about Awesome Labs, their peptide calculator app, and Awesome Breathing

Sep 26, 2022 • 43min
01: Optimal Cardiac Health and Red Light Therapy with Dr. Michael Twyman
Welcome to the first episode of Life Optimized! Today’s focus is on heart health, which is relevant to everyone. My guest shares what we should be doing in 2022 for optimal cardiac health, new tests in the cardiac field, and how red light therapy can be used for heart health and overall well being. Join us to learn more!Dr. Michael Twyman is a board-certified cardiologist focused on the prevention and early detection of heart disease. He completed his cardiovascular training at St. Louis University and completed four years of active duty as an internist at Naval Hospital Beaufort. In private practice since 2012, he utilizes the best that conventional medicine, integrative functional medicine, quantum medicine, and biohacking can deliver to get to the root cause of a patient’s cardiovascular issuesShow Highlights:How a normal person with no specific cardiac issues should assess their heart healthThe most beneficial tests to assess cardiac health: Carotid Intima-Media Thickness Test (CIMT) and CT coronary calcium scoreHow a new test, the Cleerly CCT angiogram, can go further in detecting soft plaque in the arteriesWhat an elevated CRP consistently over time says about your cardiac healthOther markers that Dr. Twyman uses to assess cardiovascular health What Dr. Twyman’s opinion is of the danger of high LDL cholesterol with no other risk factorsWhy Dr. Twyman believes there is no low cholesterol number that is “too low”How genetic testing factors into tests for cardiac healthTop risk factors for heart disease: age and diabetes When someone should get screened for heart disease beyond normal lab testsThe best changes people can make at home to improve heart health by focusing on exercise, nutrition, sleep, and stress managementA look at the coolest new heart-health technologiesHow to strike a balance between conventional treatment with statins and functional medicine tools and supplementsWhat patients should know about red light therapy, also called photobiomodulation (PBM)What patients can do for mitochondrial healthWhy circadian rhythms play a huge role in cardiac and overall health and wellnessResources:Connect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with Dr. Twymanwww.drtwyman.com and Instagram
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