Life Optimized

In this episode, we're going to discuss the latest insights and biohacking techniques to help improve brain health, with a focus on Alzheimer's disease. Learn about new medicines, supplements, and technology that can help optimize your brain performance.Show Highlights:What causes Alzheimer's disease?Which lab tests can help evaluate potential brain issues and signs of inflammation.What factors can lead to neurodegenerative symptoms.Why memory loss is a common symptom of brain issues.The latest medicines and supplements for treating Alzheimer's diseaseRecommendations for technology you can use in your own home to optimize brain performance.How you can reduce your risk of developing Azheimer's disease.ResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/

Discover the benefits of bioregulators and SS-31 peptide in promoting health and longevity. Learn about their antioxidant properties, potential for heart health and brain function, and how they can aid in healing joints and tendons. Explore the versatility of bio regulators and peptides for optimizing health and the considerations for using SS-31 in athletic training.

Today’s episode is all about fertility. We’ll be discussing various techniques to boost fertility, and the potential negative effects of birth control pills on female hormones. Cutting-edge stem cell treatments and other advancements are also discussed. We'll also cover the impact of inflammation and insulin resistance on mitochondrial function, and what that means for fitness and overall health. Show Highlights:How to reduce inflammation in your body.What can women do to boost fertility?Do stem cell treatments help with infertility?The latest advancements in female fertility treatments.How do birth control pills affect female hormones and fertility?Which lifestyle choices and supplements optimize women's sexual health?ResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/

Today’s episode is all about supplements. We’ll be discussing different kinds of supplements, which ones you should stay away from, and what makes supplements the way they are.  Listen and find out about Spermidine, Urolithin A, and more supplements that can help you in the future.Show Highlights:What are supplements?What kind of supplements are out there?Which one’s are good and bad?What’s Spermidine?Urolithin A and why it’s a strong supplement.What’s Butyrate?The two supplements that improve overall health and longevityHow sleep influences supplemental careSupplements mentioned in this episode:SpermidineUrolithin AButyrateResveratrolApigeninMetforminResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/

Dr. Andrew Hill, a peak performance coach with a Ph.D. in Cognitive Neuroscience, discusses the cutting-edge world of neurofeedback and brain health. He explains how neurofeedback can optimize brain function and potentially treat conditions like ADHD. The conversation dives into brain mapping techniques and their role in enhancing cognitive abilities. Hill also shares insights on how AI might revolutionize neurofeedback, making mental health interventions more accessible. His practical tips empower listeners to harness their brain's potential.

Ryan Smith received a BA in biochemistry from Transylvania University before heading to medical school in 2013. After passing USMLE Step 1, he decided to leave and open up a pharmacy in the United States that focused on peptide synthesis and formulations for pharmaceutical preparations. That pharmacy, Tailor Made Compounding, became the 4th fastest growing company in healthcare in the US and grew to 80 million in revenue within 3 years. Ryan exited Tailor Made in 2020 to create TruDiagnostic. TruDiagnostic is a CLIA certified lab and health data company which specializes in understanding and reporting insights found through Epigenetic methylation data. TruDiagnostics has also led research in the field with over 30+ clinical trials investigating the best ways to reverse these markers through diet, lifestyle, and prescription interventions. Currently, TruDiagnostic is working with collaborators from Duke, Harvard, Yale, UCSF, Ohio St. and more to uncover new insights from the methylome. TruDiagnostic is also the only commercial company on the market to offer 2nd or 3rd generation aging algorithms which have shown to be more predictive and precise than 1st generation aging clocks.Show Highlights:The current state of anti-aging medicineWhy it's important to measure biological age accurately The best measurement tools for anti-agingWhy you should start testing your biological age as early as possibleWhat data can tell us about the health of an individual beyond agingWhich lifestyle changes will be most helpful for optimizing your health spanResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/TruDiagnostic™ | Advanced Epigenetic Testing

In today's show I talk to Dr. Jay T. Wiles about Heart Rate Variability. We go really deep into all the aspects of HRV. From measuring it accurately to optimizing the factors that affect it. Everything you need to know and more!Dr. Jay T. Wiles is a clinical health psychologist, currently working as the Health Behavior Coordinator at WJB Dorn VA Medical Center in Columbia, SC and the Greenville Outpatient VA Clinic. He has specialized training in health behavior coaching, health assessment, nutritional interventions for mental and physical health, Motivational Interviewing, applied psychophysiology, and consultation. Dr. Wiles works as a consultant for companies/organizations, practitioners, and individual patients on nutritional psychology, health behavior change, applied psychophysiology, and health promotion/disease prevention via complementary and integrative practices.Show Highlights:What is Heart Rate Variability, and why should you measure it?How to measure your Heart Rate VariabilityThe common problems with wearable technologyOptimal ranges for your HRVHow to interpret your biometric dataWhat affects your HRV both positively and negativelyThe surprising connection between HRV and mental healthResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Home - Hanu Health, Inc. - Use code DRPAULVIN for 20% off

Today’s episode is a deep dive into peptides. There has been a lot of hype in the Biohacking community around these amazing products. Research is quickly evolving, and keeping up with the latest developments can be difficult. Listen and learn how you can get the most out of peptides to help with your healing and recovery.Show Highlights:What are peptides?How should you take peptides?The best peptides for pain and recoveryAre there risks to taking peptides?The Wolverine Stack – the ultimate in regenerative healingHow to use peptides to lower inflammationWhy you need to pay attention to mitochondrial peptidesPeptides discussed in this episode:Thymosin Alpha 1ThymulinBPC157CJC 1295Melanotan 1 & 2Thymosin Beta 4 (TB4)TB5GHK CopperPentosan PolysulfateAOD9204P21M677TesamorelinKPVMOTS-CSS 31Resources:Connect with Dr. Paulvinhttps://doctorpaulvin.com/

Today’s show is a deep dive into exogenous ketones. You’ll learn about the latest advances and products, what the benefits are, and what to expect from the upcoming research in this exciting field. I’m joined by Frank LLosa, the CEO and founder of KetoneAid. He’s an expert on all things ketones, and I’m excited to have him on today’s show to help us learn more!Show Highlights:What are exogenous ketones?Your body’s fuel source: glucose or ketonesWhy we should beware of the misinformation in the world about products related to ketones and ketosisHow to understand ketone esters, BHB, and what they do for the bodyThe top benefits of using a ketone product: recovery, mental cognition, and sleepHow exogenous ketones should be taken (Too much of a good thing is NOT good!)What to expect from exogenous ketones in brain activityHow following the keto diet differs from taking exogenous ketonesWhat exogenous ketones can do for high-performance athletes and average athletesHow to be an educated consumer in today’s ketone marketWhere the future is headed in the field of exogenous ketonesAn overview of products available at KetoneAid (including their upcoming ketogenic, gluten-free beer!)Where ketone science is headed for the futureResources:Connect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with Frank and KetoneAidwww.ketoneaid.com, Instagram, Facebook, and YouTube

We are diving deep into some of today’s most popular scientific breakthroughs in the field of health optimization. My expert guest shares real-life applications from his wealth of knowledge and experience. Join us to learn more about feeling better, looking better, and adding years to your health span!Dr. John Sottery is a Ph.D. scientist who believes that “aging normally” is a disaster. As a 63-year-old with young children, he is incredibly focused on maximizing his health and lifespan. His goal is to teach others how to outperform their chronological age through mitochondrial and cardiovascular health, and he focuses his research on ways to turn on the body’s genes that will drive protection and repair. After obtaining his doctorate in chemistry from Duke University, he led project development teams at Procter & Gamble before leaving to start several companies of his own. Through his work today, he attacks problems to understand them at a molecular level to maximize health span, slow down the damage, and accelerate repair in the body. Show Highlights:What is most important to know in optimizing mitochondrial healthWhy we need to understand what damages mitochondria, how to get rid of the damaged ones, and how to create new mitochondria from undamaged onesDr. John’s #1 tip for mitochondrial health: Don’t eat within three hours of going to bed.How to push your mitochondria with ice baths, saunas, or HIIT workouts–so that your body knows how to recycle defective mitochondriaHow to understand the basics of intermittent fasting, autophagy, antioxidants, and free radicalsWhy broccoli sprouts are good for us–and other foods that turn up Nrf2How the body’s phase 2 toxification enzymes work to eliminate carcinogensDr. John’s take on getting vital nutrients from food vs. relying on supplementsHow to get the most nutrition out of the broccoli you eatHow fasting, exercise, Resveratrol, and spermidine help turn up autophagyHighlights of the overall benefits of spermidine, including recent research about preventing colon cancer and osteoporosisSources and benefits of ergothioneine (an amino acid found primarily in mushrooms)Why copper can be the difference between mild cognitive impairment and full-blown Alzheimer’s (Eat your mushrooms!)Why YOUR body has its own recipe for optimal healthDr. John’s final thoughts about how excess fructose, alpha tocopherols, and omega-6 fats are harming peopleResourcesConnect with Dr. Paulvinhttps://doctorpaulvin.com/Connect with Dr. Johnwww.johnsottery.com, Facebook, and YouTubeMentioned in this episode: Dr. Guido Kroemer on YouTube, Nature Wants Us to Be Fat by Dr. Richard Johnson and Drop Acid by Dr. David Perlmutter