Reason is co-founder and CEO of Repair Biotechnologies. He has been an active angel investor in the longevity industry since its earliest days, with investments including Oisin Biotechnologies and Leucadia Therapeutics. He is a long-standing and well-connected patient advocate for aging research, involved in numerous fundraising and outreach initiatives conducted by organizations such as the Methuselah Foundation and SENS Research Foundation since the early 2000s. He is also the founder and writer of Fight Aging!, a noted news and commentary website in the biotechnology community.Cholesterol is presented as much an enemy as a friend in this look at how direct clearance of localized excess cholesterol outperforms other strategies in a number of important medical conditions.Session summary: Reason, Fight Aging | Towards Biotechnology to Finally Defeat Cholesterol - Foresight InstituteThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts. Hosted on Acast. See acast.com/privacy for more information.

In this episode of Foresight’s Existential Hope Podcast, our special guest is Kevin Kelly, an influential figure in technology, culture, and optimism for the future. As the founding executive editor of Wired and former editor of Whole Earth Review, Kelly's ideas and perspectives have shaped generations of thinkers and technologists.Join our hosts Allison Duettmann and Beatrice Erkers as they delve into Kelly's philosophies and experiences, from witnessing technological shifts over the decades to fostering optimism about the future. Kelly shares details about his latest book, a collection of optimistic advice in tweet form, and talks about his current project envisioning a desirable hi-tech future 100 years from now.He also discusses the transformative power of the internet as an accelerant for learning, the underestimated long-term effects of being online, and the culture-changing potential of platforms like YouTube. If you're interested in the intersection of technology, optimism, and the future, this podcast episode is a must-listen.Full transcript, list of resources, and art piece here.Existential Hope was created to collect positive and possible scenarios for the future, so that we can have more people commit to the creation of a brighter future, and to start mapping out the main developments and challenges that need to be navigated to reach it. Find all previous podcast episodes here, always featuring a full transcript, artwork inspired by the episode, and a list of recommended resources from the podcast. Existential Hope is a Foresight Institute project. The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. Beatrice Erkers is COO at Foresight Institute, and program manager of the Existential Hope group. Her special interest in the integration of technology and society has led her to work for Foresight Institute.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts. Hosted on Acast. See acast.com/privacy for more information.

Jaan Tallinn is a co-founder of the Centre for the Study of Existential Risk in Cambridge, the Future of Life Institute in Cambridge and a founding engineer of Skype. Session summary: Foresight Mentorship with Jaan Tallinn - Foresight InstituteThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

How can #shieldedtransactions/#privacy-protecting initiatives change the way we interact in society? What can we do to safeguard our identities in the future of this #crypto economy? Are there certain utopias and dystopias to embrace or to avoid?Zaki Manian wears many hats in the blockspace. He is currently a cofounder of the iqlusion. They are working Armistice, an open source hardware security solution. Iqlusion advises, and supports a number of blockchain projects. He is also an advisor to the Electric Coin Company. He taught himself after college software engineering, programming and computer science. From 2008-2013, he was tech lead on scientific instrumentation product at ReaMetrix. He started an enterprise blockchain company called Skuchain in 2014 and started teaching himself cryptography.In 2017, Zaki co-founded the Trusted IoT Alliance and iqlusion, and also started contributing more to Cosmos. He helped build the first validator dashboard and then Figment ran with the idea. He helped launch the first public Cosmos testnets. He spent a lot of 2018 working part time at All In Bits, building out the validator ecosystem, and figuring how to do quality assurance to enable the Cosmos launch.After All In Bits proved too unstable to finish the work, he resigned in Feb 2019 and is completing the IBC work with the community from contributors from Agoric, Interchain Berlin and Informal.https://zaki.manian.org/The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.The host, Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

Natalie Dullerud is a first-year PhD student at Stanford University and recently received her Master’s from University of Toronto. She previously graduated with a Bachelor’s degree in mathematics from University of Southern California, with minors in computer science and chemistry. Natalie’s research largely focuses on machine learning through differential privacy, algorithmic fairness, and applications to clinical and biological settings.Machine learning benefits from large training datasets, which may not always be possible to collect by any single entity, especially when using privacy-sensitive data. In many contexts, such as healthcare and finance, separate parties may wish to collaborate and learn from each other’s data but are prevented from doing so due to privacy regulations. This talk will describe Confidential and Private Collaborative (CaPC) Learning, a recently published framework that allows entities to collaborate via privacy-preserving mechanisms in order to improve their own local models and maintain data privacy, from both a cryptographic and differentially private definition. The talk will encompass current definitions, concerns and techniques in the private distributed learning setting, then turn to the technical details and advantages to CaPC in practical settings. Session summary: Natalie Dullerud | CaPC - Confidential and Private Collaborative Learning - Foresight InstituteThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

David Deutsch, a physicist and writer, has a broad interest in fundamental concepts. He is credited with discovering the first quantum algorithm and, together with Richard Jozsa, discovering the first quantum algorithm capable of solving certain problems exponentially faster than classical computer science.Deutsch discusses the intersection of beauty, knowledge, and progress in this episode of Foresight's Existential Hope Podcast. Deutsch's innovative work on quantum algorithms and constructor theory is explored, along with his insights on critical thinking, AI alignment, education, and human progress. The conversation is enlightening and thought-provoking, making it a must-listen for anyone interested in cutting-edge ideas and research.Full transcript, list of resources, and art piece: https://www.existentialhope.com/podcasts Existential Hope was created to collect positive and possible scenarios for the future, so that we can have more people commit to the creation of a brighter future, and to start mapping out the main developments and challenges that need to be navigated to reach it. Find all previous podcast episodes here, always featuring a full transcript, artwork inspired by the episode, and a list of recommended resources from the podcast. Existential Hope is a Foresight Institute project. The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Beatrice Erkers is COO at Foresight Institute, and program manager of the Existential Hope group. She has a background in the publishing industry and has several years of experience working with communication at Foresight and at a publishing house. Her special interest in the integration of technology and society has led her to work for Foresight Institute.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts. Hosted on Acast. See acast.com/privacy for more information.

What does the future hold for shielded transactions? How can #shieldedtransactions/#privacy-protecting initiatives change the way we interact in society? What can we do to safeguard our identities in the future of this #crypto economy? Are there certain utopias and dystopias to embrace or to avoid?*Avichal Garg, Electric Capital | Shielded Transaction Special | Trailer*Avichal Garg is a co-founder and partner on the investment team at Electric Capital. He is a successful serial entrepreneur with executive experience at Google and Facebook, which acquired his previous company in 2012. At Facebook he was Director of Product Management for the Local product group, a team of 400 engineers responsible for billions in revenue.Prior to Electric, Avichal was an investor in crypto projects such as Anchorage, Bitwise, Celo, dYdX, Lightning Labs, and OpenSea and unicorns such as Airtable, Boom Supersonic, Color Genomics, Cruise, Deel, Figma, Material Secutiy, Newfront Insurance, Notion, Nova Credit, and Pulley.https://avichal.com/The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

Vadim Gladyshev is a Professor of Medicine at Harvard Medical School, Director of the Center for Redox Medicine at Brigham and Women's Hospital, and Associate Member of the Broad Institute. Mahdi Moqri is an NIH Postdoctoral Fellow in Aging Research at the Sebastiano Lab at the Institute for Stem Cell Biology and Regenerative Medicine at Stanford, and a visiting scholar at the Gladyshev Lab at Harvard Medical School. Mahdi Moqri is an NIH Postdoctoral Fellow in Aging Research at the Sebastiano Lab at the Institute for Stem Cell Biology and Regenerative Medicine at Stanford, and a visiting scholar at the Gladyshev Lab at Harvard Medical School.  With the rapid expansion of aging biology research, identification and evaluation of longevity interventions in humans have become key goals of this field. Biomarkers of aging are critically important tools in achieving these objectives over realistic timeframes. Here, we advance a framework for characterizing and assessing biomarkers of aging, including consensus terminology for several key concepts in this space. We propose classification of existing biomarkers and evaluate their feasibility, age-sensitivity, mechanistic underpinnings, and response criteria.  Session summary: V. Gladyshev, M. Moqri, V.Sebastiano | Quantifying Aging - Foresight InstituteThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

This Neurotech Special: Whole Brain Emulation and Artificial General Intelligence (AGI) Virtual Meeting Seminar brings together leading researchers, engineers, and entrepreneurs to discuss the latest advances in whole brain emulation (WBE) and its implications for AGI. This seminar aims to explore the technical, ethical, and societal challenges that emerge as we venture into the realm of replicating and augmenting human intelligence.Session summary: https://foresight.org/summary/neurotech-special-wbe-agi-virtual-seminar-meeting/ Upcoming workshop on the topic: https://foresight.org/whole-brain-emulation-workshop-2023/The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

In this episode of the Existential Hope Podcast, we have the pleasure of interviewing Anders Sandberg, a Swedish philosopher, and researcher at the Future of Humanity Institute at Oxford University.During our conversation with Anders, we explore the concept of grand futures and what it means to strive for them as a society. We discuss the potential benefits and risks of emerging technologies such as artificial intelligence, nanotechnology, and biotechnology, and how we can navigate these developments responsibly.Full transcript, list of resources, and art piece: Anders Sandberg | Grand Futures & The Post-Human Coral ReefExistential Hope was created to collect positive and possible scenarios for the future, so that we can have more people commit to the creation of a brighter future, and to start mapping out the main developments and challenges that need to be navigated to reach it. Find all previous podcast episodes here.The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Beatrice Erkers is Chief of Operations at Foresight Institute, and program manager of the Existential Hope group. She has a background in publishing and years of experience working with communication at Foresight and at a publishing house. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts. Hosted on Acast. See acast.com/privacy for more information.