AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
The Foresight Institute Podcast
David Dalrymple | Rethinking Uploading Given 10-Year AI Timelines
Nov 17, 2023
Neuroinformatics and machine learning researcher David Dalrymple discusses a 10-year plan for brain uploading, AI techniques for parameter estimation, challenges of dense brain data transfer, and potential solutions. Also explores techniques and challenges in studying synapses and receptors in the brain and building datasets for AI learning.
08:24
Episode guests
AI Summary
AI Chapters
Episode notes
Podcast summary created with Snipd AI
Quick takeaways
- The use of expansion microscopy and immunofluorescence shows promise for brain uploading within the next 10 years.
- Validation techniques involving human brain slices and computational models can help fill in parameters for deeper understanding of the system.
Deep dives
Rethinking uploading with neural dust and expansion microscopy
In this podcast episode, David Dalvin discusses his perspective on rethinking uploading, focusing on two approaches that have potential. The first approach involves using neural dust and ultrasound to record and communicate with the living human brain. However, the challenge lies in the need for super high-resolution magnetic field imaging, which may not be possible within the next 10 years. The second approach utilizes expansion microscopy, which allows for high-resolution imaging of synapses. By incorporating techniques like m-cling or heavy metal stains, it may be possible to combine expansion microscopy with electron microscopy for further analysis. Although there are challenges, such as the need to tag dozens of proteins and develop highly scalable robotic sample slicing, these approaches present possibilities for advancing uploading.
Get the Snipd
podcast app
Unlock the knowledge in podcasts with the podcast player of the future.
AI-powered
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode
Save any
moment
Hear something you like? Tap your headphones to save it with AI-generated key takeaways
Share
& Export
Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more
AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode