Metagenics Institute Podcast

Whether you’re intrigued by the science of sleep or simply looking for tools to improve your sleep quality, there’s no doubt you’ll appreciate this podcast episode. Nathan’s guest, Greg Potter, has a PhD in sleep patterns, dietary habits and metabolic health, and his research has been featured in the likes of TIME magazine and The Washington Post. Potter expertly answers all-important questions such as how much sleep do we actually need? What do sleep tracking devices offer? And how does CBT-I help in the quest for a good night’s rest? Enjoy the pillow talk with Greg Potter. *Highlights * • The impact of sleep on the immune system (3:10) • Night-time sleep affects day-time mood (8:00) • How much sleep do we actually need? (12:10) • Sleep and ageing (17:40) • Tracking your sleep (19:40) • Why you can’t sleep (30:00) • How to improve your sleep (34:30) • All about CBT-I (37:00) • Sleeping aids and supplements (52:15) Useful links and resources: e.g: CBT-I research links - Systematic Review and Meta-Analysis – 2015 https://pubmed.ncbi.nlm.nih.gov/26054060/?from_term=insomnia&from_filter=pubt.meta-analysis&from_filter=pubt.randomizedcontrolledtrial&from_filter=pubt.systematicreviews&from_filter=years.2015-2020&from_pos=2 Effect of Digital Cognitive Behavioral Therapy for Insomnia on Health, Psychological Well-being, and Sleep-Related Quality of Life: A Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/30264137/?from_term=insomnia&from_filter=pubt.meta-analysis&from_filter=pubt.randomizedcontrolledtrial&from_filter=pubt.systematicreviews&from_filter=years.2018-2020&from_page=3&from_pos=6 The Effectiveness of Behavioural and Cognitive Behavioural Therapies for Insomnia on Depressive and Fatigue Symptoms: A Systematic Review and Network Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/28619248/?from_term=insomnia&from_filter=pubt.meta-analysis&from_filter=pubt.systematicreviews&from_filter=years.2018-2020&from_page=4&from_pos=3 Digitally-delivered Cognitive-Behavioural Therapy for Youth Insomnia: A Systematic Review Results showed that eCBT-I improved sleep efficiency, sleep quality, sleep-onset latency and total sleep time with effect sizes ranging from 0.17-1.30 (Cohen's d). https://pubmed.ncbi.nlm.nih.gov/30135762/?from_term=insomnia&from_filter=pubt.meta-analysis&from_filter=pubt.systematicreviews&from_filter=years.2018-2020&from_page=6&from_pos=7 Some devices mentioned: Ebb device – https://www.ebbsleep.com/ Photobiomodulation device – https://joovv.com/ Oura ring - https://ouraring.com/

From 1994 until 2004 Jane McLelland battled two aggressive cancers with metastatic spread. Using her medical knowledge and researching heavily, she put together a cancer-starving formula, using natural therapies, exercise, diet and a unique cocktail of medications. Her personalised prescription saw her cancer “melt away”. Listen in to hear her remarkable story, and share her wisdom concerning cancer management. *Key Highlights * Jane McLelland’s story (1:55) How Jane created her famous ‘metro-map’ (17:00) Cancer fuel sources (24:00) Can we determine the fuel source for specific cancers? (30:00) Commentary regarding off-label drugs (38:00) Natural constituents (47:00) Drug recommendations (53:00) Ingredients critical to include in the cocktail (60:00) Useful links and resources: e.g: Jane McLelland’s website: https://www.howtostarvecancer.com/ Jane’s McLelland’s book - https://www.howtostarvecancer.com/the-book/

In his words, Dr Brad Dieter’s goal is to use analytics, data science, and a deep understanding of scientific principles to help solve advanced problems. With a background in exercise physiology, molecular biology and biostatistics, Brad proves an excellent guest, as he and Nathan cover the natural history of diabetes and screening tests to assess insulin resistance, to diet debates and the development of obesity – Is it simply a matter of calories in versus calories out? You will have to listen to find out! *Key Highlights * How Brad got started in this field (1:40) A pathophysiology lesson to start (5:10) Looking at the biomarkers (14:15) What drives obesity? Examining the hypotheses (20:00) Looking closer at diets (25:30) Transferring the research into clinic (36:40) Weighing up the ketogenic diet (40:40) Examining personalised nutrition (46:05) Useful links and resources: e.g: https://macrosinc.net/

Whether you are new to Emotional Freedom Technique (EFT), or are a seasoned ‘tapper’, this podcast episode is guaranteed to keep you engaged. Interviewee, Dr Peta Stapleton, is a clinical and health psychologist as well as associate professor in psychology at Bond University. Peta has led world-first randomised clinical trials investigating Emotional Freedom Techniques, adding a wealth of research to this field. *Key Highlights * The origins of EFT (2:30) What does a session involve? (6:10) Is tapping the acupoints essential? (8:35) The effect of EFT on physiology (13:00) Review of the research outcomes (17:30) The astonishing results for cravings and weight loss (27:00) Tapping as a tool for processing emotion (38:00) Navigating addiction with tapping (47:00) The practicalities – training and certification (51:00) Useful links and resources: Follow Metagenics Instagram - @metagenics_anz or Facebook - https://www.facebook.com/metagenics/ If you hold a Metagenics account in Australia or New Zealand join our Facebook Group here - https://www.facebook.com/groups/MetagenicsAU/ Dr Peta Stapleton’s website - https://petastapleton.com/ The Science Behind Tapping - https://petastapleton.com/the-science-behind-tapping/ Guidelines for the Treatment of PTSD Using Clinical EFT (Emotional Freedom Techniques) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316206/ The Effectiveness of Emotional Freedom Techniques in the Treatment of Posttraumatic Stress Disorder: A Meta-Analysis - https://pubmed.ncbi.nlm.nih.gov/27889444/ Emotional Freedom Techniques for Anxiety: A Systematic Review With Meta-analysis - https://pubmed.ncbi.nlm.nih.gov/26894319/ A Systematic Review and Meta-Analysis of Randomized and Nonrandomized Trials of Clinical Emotional Freedom Techniques (EFT) for the Treatment of Depression - https://pubmed.ncbi.nlm.nih.gov/27843054/

Back by popular demand! Associate Professor Dr Karin Ried joins Nathan to discuss the National Institute of Integrative Medicine’s ISET®-CTC test. Ried explains how the test detects CTCs, including how it can distinguish between malignant CTCs and benign circulating epithelial cells, as well as nuances around interpretation of results and the value of monitoring CTCs. Enjoy the highly informative conversation with Dr Ried. *Highlights * A very good place to start – what is a CTC? (1:30) The role the ISET®-CTC test has in integrative oncology (8:00) Nuances around result interpretation (12:40) Comparing this test to marker tests (21:20) Emphasis on the role of the immune system (29:50) Delivering results to patients (33:20) Delving into cancer screening (39:00) Learnings from examining prostate cancer (40:00) The value of monitoring CTCs (53:30) Therapeutic considerations (105:00) Useful links and resources: e.g: Follow Metagenics Instagram - @metagenics_anz or Facebook - https://www.facebook.com/metagenics/ If you hold a Metagenics account in Australia or New Zealand join our Facebook Group here - https://www.facebook.com/groups/MetagenicsAU/ Paper – ‘New Screening Test Improves Detection of Prostate Cancer Using Circulating Tumor Cells and Prostate-Specific Markers’ - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192049/

Dr Mark Burhenne has been practising dentistry for over 30 years and is the author of the #1 best seller, The 8-Hour Sleep Paradox. His passion for oral health and the importance of healthy sleep shines through in this episode, as he offers important insights about the oral microbiome, P gingivalis and sleep apnoea. *Key Highlights * Burhenne’s short story (1:40) Welcome to the oral microbiome (6:10) Focus on P gingivalis (10:30) Can treating periodontitis improve other disease activity? (15:50) Conventional treatment for periodontitis (18:40) Natural considerations (23:30) All about biofilms and why we should reconsider using essential oils (26:45) Shining light on sleep apnoea (31:20) Why you should seek out a functional dentist (50:30) Useful links and resources: e.g: Follow Metagenics Instagram - @metagenics_anz or Facebook - https://www.facebook.com/metagenics/ If you hold a Metagenics account in Australia or New Zealand join our Facebook Group here - https://www.facebook.com/groups/MetagenicsAU/ Dr Mark Burhenne’s website – https://askthedentist.com The 8-Hour Sleep Paradox: How We Are Sleeping Our Way to Fatigue, Disease and Unhappiness - https://www.amazon.com.au/8-Hour-Sleep-Paradox-Sleeping-Unhappiness-ebook/dp/B015DIQBZ6 The Dental Diet – Dr Steven Lin

Dr. Scott Antoine’s résumé includes 24 years practicing as an Emergency Medicine Physician and six years practicing Functional Medicine. As you can appreciate, he has a wealth of knowledge and practice under his belt, and is well placed to provide an update on Coronavirus pathophysiology and the role of potential therapies in preventing and managing the condition. *Key Highlights * • How Antoine found his way from ER to Functional Medicine (1:45) • The difficulty with examining the prevalence of Coronavirus (7:20) • Pathophysiology update (14:30) • Navigating therapies for Coronavirus (25:20) • The potential of Methylene blue (29:35) • The cytokine storm (35:50) • What can we do to prevent and manage Coronavirus? (41:20) • Special mention to quercetin (49:30) • Stress-related considerations (53:30) *Useful links and resources: * Link to Dr. Scott Antoine’s clinic: www.vinehealthcare.com Link to Antoine’s research – ‘A Literature Review Supporting the Addition of Intravenous Methylene Blue, High-dose Intravenous Vitamin C, Intravenous Glutathione, and Nutraceuticals, to Standard Care for Hospitalized COVID-19 Patients’ https://www.vinehealthcare.com/wp-content/uploads/2020/04/COVID-19-Novel-Therapeutics-A-Comprehensive-Review-of-the-Literature.pdf Link to article - ‘Coronavirus (COVID-19), First Indication of Efficacy of Gene-Eden-VIR/Novirin in SARS-CoV-2 Infections’ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146686/ Link to article – ‘A cohort of cancer patients with no reported cases of SARS-CoV-2 infection: the possible preventive role of Methylene Blue’ https://riviste.fupress.net/index.php/subs/article/view/888 Link to article – ‘Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths’ https://www.mdpi.com/2072-6643/12/4/988 Link to article – ‘A new clinical trial to test high-dose vitamin C in patients with COVID-19’ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137406/

Coronavirus has brought about a great deal of changes and uncertainty in society. Rose sits down with clinical psychologist, Dr Adrian Lopresti, to discuss the mental and social implications of living with this pandemic. They discuss how to maintain a healthy mindset, including what to do and what not to do, as well as adjusting to new routines in lieu of this significant disruption to our lives. *Key Highlights * • The social and emotional toll of Coronavirus (3:00) • Practical strategies to help manage our exposure to information (8:00) • Incorporating an integrated approach for wellness (9:15) • Advice for our children (15:30) • Using the time to reflect (18:00) • Mindfulness practices (21:20) • Supplement considerations (25:40) • Establishing a new routine (28:30) • Dr Lopresti’s recent research and PI therapy (40:00) *Useful Links & Resources * https://pitherapy.com.au/

This episode provides a synopsis on the Coronavirus with a natural twist. Rose sits down with the perfect guest, Dr Heather Zwickey, who is both knowledgeable and articulate. Dr Zwickey has a PhD in immunology and microbiology, and is currently working as a professor and researcher examining the effects of natural medicines on the immune system. Key Highlights • Dr Zwickey’s origins in immunology (1:35) • Virus = SARS-CoV-2. Disease = COVID-19 (3:10) • Why is this virus more pathogenic than other viruses? (4:10) • What is emerging data telling us about the spread of this virus? (8:15) • COVID-19 in comparison to previous pandemics (9:55) • 48 hours from exposure to symptoms (11:30) • Who is at risk? (13:50) • Conventional treatments available for Coronavirus (22:55) • The potential of natural medicine (29:00) • Is there any risk in supplementing with vitamin D and zinc? (37:10) Useful link: https://heatherzwickey.com/

Research examining photobiomodulation, previously known as low level laser (light) therapy, shows promise for a wide range of ailments, from musculoskeletal complaints to degenerative diseases and psychiatric disorders. This episode covers all the basics and more, including a discussion regarding its mechanism of action and existing research as well as practical advice such as how to choose a light therapy device. Settle in as this podcast serves up a perfect introduction to photobiomouldation. *Key Highlights * • How Scott Nelson arrived in the world of photobiomodulation (3:20) • The foundations (6:30) • How the body harnesses and uses light energy (9:40) • Diving into the applications of light therapy (15:00) • Examining the clinical studies (19:40) • Psychiatric and cognitive health (20:50) • Pain and inflammation (31:00) • Cancer (33:00) • What else does photobiomodulation have to offer? (42:30) • Choosing a device for you and your patients (45:00) Useful links and resources: Light therapy device: Joov - https://joovv.com/ Research: Transcranial Photobiomodulation for the Treatment of Major Depressive Disorder. The ELATED-2 Pilot Trial - https://www.ncbi.nlm.nih.gov/pubmed/30346890 Effects of Low-Level Laser Therapy in Autism Spectrum Disorder - https://www.ncbi.nlm.nih.gov/pubmed/29956199 Systematic review of photobiomodulation for the management of oral mucositis in cancer patients and clinical practice guidelines - https://www.ncbi.nlm.nih.gov/pubmed/31286228