Original Air Date: 09/15/2010In 1987, AIDS patient Mike Sisco jumped into a community pool causing a city-wide uproar and spread of misinformation. At the time, Oprah hosted a heated town hall style show in Williamson where the audience famously debated each other about the dangers, myths and facts about AIDS. 23 years later, Oprah returned to Williamson, West Virginia to speak with the many residents who were disgusted, scared, supportive and hopeful.

Original Air Date: 04/15/2011At times he wasn’t given any food or water for days, all while being chained inside a tiny closet. At age 19, Clayton speaks out for the first time about the torture he endured at the hands of his father and stepmother when he was six. Plus, Oprah speaks with the man who saved Clayton’s life.

Original Air Date: 09/23/2010She was a hiker accused of being an American spy and was held hostage in an Iranian prison for 14 months. Just days after her return to the United States, Sarah Shourd talks to Oprah. Plus, a woman’s ex-boyfriend put up an ad to get revenge. The Craigslist rape survivor reveals her identity and tells her story for the first time.

Original Air Date: 11/26/2010Throughout the course of The Oprah Winfrey Show, Oprah turned a simple 'thank you' into an art form. In her thank-you day follow-up, Oprah revisits some of the most unforgettable moments of gratitude that occurred during the show's 25 seasons. Oprah also checks in to see where these guests are and what they were doing in 2010.

Original Air Date: 04/07/2011To the outside world Marie Walsh was living the American dream. She had a happy 22-year marriage and was a devoted mother to three children. She played bridge, tennis and rode horses in her upper-middle-class San Diego suburb. In truth, Marie was living a life she had spent decades crafting to hide her identity. Marie was really Susan LeFevre—a fugitive who had been hiding from the law for 32 years. In 1975, 19-year-old Susan was arrested for selling 2.5 grams of heroin to an undercover Michigan State Trooper. She pled guilty and was sentenced to 10 to 20 years in prison. After a year behind bars, Susan's grandfather helped her escape. With just clothes, a toothbrush and $200, Susan fled to California to start a new life, under a new identity: Marie. It was a headline that grabbed the nation’s attention and deeply divided public opinion. Marie opens up to Oprah about how she lived a secret life for 32 years.

Original Air Date: 10/25/2010In an instant, a car accident shattered the lives of Lori and Chris Coble. One year later, a miraculous twist of fate changed their lives again. It’s a story you must hear to believe. Also, Virginia Tech Massacre survivor Colin Goddard secretly films people selling him weapons at a gun show for cash with no I.D. required.  

Original Air Date: 04/18/2011From a 276-car giveaway to a flash mob of 20,000 dancers to thousands of Favorite Things… Oprah’s producers are sharing their favorite behind-the-scenes moments and revealing the best-kept secrets of Harpo history!

Original Air Date: 11/23/2010A single mother decides to marry a felon who will be behind bars for life. Oprah speaks to the unconventional couple and how they make their love story work. Then, Oprah speaks to the many women who are leaving their world behind to join the convent as nuns, getting a rare look inside their sacred space.

Original Air Date: 02/16/2011Before Dr. Phil and Dr. Oz, Iyanla Vanzant was blazing the trail at The Oprah Winfrey Show. And then, it was over. Now, what really happened between Oprah and Iyanla Vanzant. Listen to what happens when Oprah and Iyanla reunite on The Oprah Winfrey Show stage after 11 years.

Original Air Date: 02/23/2011Iyanla Vanzant is back to discuss her marriage, her dream home, her multimillion-dollar fortune and how it all vanished. She explains how she pulled herself back from the brink. Iyanla shares what she learned from her no-holds-barred conversation with Oprah. Iyanla also brings listeners inside her broken marriage. Iyanla also speaks candidly about her bout with depression after her daughter's death.