LaBossiere Podcast

Economist Robin Hanson discusses aliens potentially domesticating humans, the argument against intelligent life in the universe, analyzing UFO sightings, signaling and hidden motives, surprising perspective on medicine, realness of taste, game theoretic equilibria and hyper-rationality, predicting the future, the concept of the sacred, and the importance of institutional innovation.

Chris Mason, Professor of Genomics, Physiology, and Biophysics at Weill Cornell Medicine, discusses topics such as the potential longevity of humanity, the NASA twin study on space travel effects, space colonization and regulation, predictive algorithms and AI, the fascination with science and genetics, the problems with science and academic research, and the future of human life including synthetic biology and Mars settlement.

Keith Rabois, General Partner at Founders Fund and CEO of OpenStore, talks about topics such as the PayPal Mafia, spotting talent, regulatory arbitrage, AI, operating strategies, founding vs investing, early-stage investing, companies as cults, the future of venture, and the power of serendipity in this podcast.

Bradley Tusk is a venture capitalist, political strategist, philanthropist and writer. He is the CEO and co-founder of Tusk Ventures, the world’s first venture capital fund that invests solely in early stage startups in highly regulated industries, and the founder of political consulting firm Tusk Strategies. Bradley’s family foundation is funding and leading the national campaign to bring mobile voting to all U.S. elections. Tusk Philanthropies also runs and funds anti-hunger campaigns that have led to the creation of anti-hunger policies and programs (including universal school breakfast programs) in 22 different states, helping to feed over 12.5 million people. Bradley is the author of The Fixer: My Adventures Saving Startups From Death by Politics and Obvious in Hindsight (coming out this November), writes a column for Fast Company, hosts a podcast called Firewall about the intersection of tech and politics, and is the co-founder of the Gotham Book Prize. He recently opened a bookstore, podcast studio, event space and cafe called P&T Knitwear on Manhattan's lower east side. He is also an adjunct professor at Columbia Business School. 0:00 - Intro 2:03 - The Incentives of Politics 10:57 - Bradley’s Philosophy 18:33 - More Political Parties and Fixing Political Polarization 25:13 - Big Tech Antitrust 29:09 - What Bradley Would Change 32:23 - The Decline of Trust in Institutions  36:12 - Tusk Ventures 37:53 - Requests for Startups 39:50 - Debt, Inflation, and COVID 46:31 - The Story of Uber  49:29 - How Uber Beats Lyft 52:59 - Weaponizing a Constituency  54:53 - Regulated Industries Bradley’s Excited About  57:54 - Crypto 1:01:40 - Psychedelics and Doing Ketamine  1:07:21 - What Keeps Bradley Up at Night? 1:10:48 - Mobile Voting  1:15:41 - Doing Lots of Things at Once 1:18:25 - Why Credentials Are Overrated 1:23:42 - On Happiness 1:28:31 - What Should More People Be Thinking About? 🎙️More Episodes🎙️ YouTube: ⁠⁠https://bit.ly/3QDLQFt⁠⁠ Apple: ⁠⁠https://apple.co/478Be6M⁠⁠ Spotify: ⁠⁠https://spoti.fi/3sfiFiE

Jeff Morris Jr, former VP at Tinder turned VC, discusses growing up in Silicon Valley, AI in content, future of product, crypto, and building Chapter One. Also, talks about $10,000 for Michael Jordan's cigar, mentors, and personal philosophy.

Sari Azout, a seed stage investor and product strategist dedicated to enhancing collective intelligence, shares her insights on the contrasts between founding and investing. She dives into the complexities of modern parenting, emphasizing the importance of fostering independence in children. Azout also discusses the need for better tools in knowledge sharing and curation, critiquing the superficial nature of current content creation. Additionally, she advocates for long-term thinking and the value of solitude for personal growth and emotional well-being.

On optimism, progress in technology, drivers of stagnation, and how to think about innovation.

On Immortal societies, civilizational decline, the longevity of information, and academia.

On apologies, academia, quitting, critical thinking, and scaling great ideas.

On the internet’s biggest problems, social networks as open protocols, and pseudonymity online.