Big Picture Medicine

0:00 Intro 0:54 Is AI Too Powerful? 17:59 Outlive, Peter Attia's New Longevity Bible 45:16 Why Are Americans Dying So Young? Joined by:  Dr Adam Bataineh: Longevity doctor and Co-founder Span Health (acquired by EightSleep).  Dr Imran Mahmud: Investor, Oxford-trained doctor, ex-Mckinsey and Co-founder of NYE Health.  Dr Mustafa Sultan: Creator of Big Picture Medicine and Doctor.

Dr John Whyte is the Chief Medical Officer of WebMD, he’s also worked at Director level at the FDA and was also Chief Medical Expert at the Discovery Channel. 0:00 Intro 0:54 Anxiety as a content creator 2:33 Why should executives think like physicians? 7:23 Decision-making with limited information 10:47 Bayesian reasoning 12:57 Risk, acuity and stress 15:28 What should we NOT learn from physicians? 17:06 Future of health communication, health influencers 22:29 Regulation for health influencers? 24:22 Habit: I've never applied for a job 26:53 Networking building 28:24 Introspection as a habit for success John runs a course called 'Think Like a Doctor to Make Executive Decisions' — and I ask about different frameworks executives can pick up from doctors and use in non-healthcare settings (such as bayesian reasoning and assessing what is a symptom vs a cause). John’s also a veteran of the health communication space, and we discuss where the future of health content is going, and the art of storytelling. John's course: https://www.linkedin.com/learning/think-like-a-doctor-to-make-executive-decisions You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

0:00 Intro 1:00 AI drug development 7:04 Big picture impact of AI drug development 9:14 Counterintuitive facts about drug development 11:06 Why can't we just make novel drugs with AI? Biology is hard 19:06 Microsoft's GPT-4 healthcare play 26:48 The hardest thing about health startups 31:49 Outro Joined by:  Dr Adam Bataineh: Longevity doctor and Co-founder Span Health (acquired by EightSleep).  Dr Imran Mahmud: Investor, Oxford-trained doctor, ex-Mckinsey and Co-founder of NYE Health.  Dr Mustafa Sultan: Creator of Big Picture Medicine and Doctor.

Dr Shivdev Rao is a Cardiologist and CEO/Co-founder of Abridge, who have raised over $22M. Think of Abridge like an Alexa or Siri (or other voice assistant) that sits there whilst the physician and patient talk. Instead of the physician writing notes during the consult, or staying late and charting — Abridge listens to the conversation and writes up the notes for them. Similarly, instead of the patient frantically taking notes, or being bombarded with information — most of which they will forget — Abridge can send them an appropriately-pitched record of what was said, with key takeaways. We talk about how Shiv built and grew this company, I ask him about the existential threat of LLMs like ChatGPT, how being in the intensive care unit is similar to building a startup, and how operating from a place of abundance is a key to success. 0:00 Intro 1:35 Shiv's story 8:50 Cross pollination as a tech CEO 12:02 Abridge, idea to execution 17:19 Possibilities with big data 19:53 Threat of LLMs like ChatGPT 23:52 How will Abridge fail? 25:22 How to stay focused 27:10 Leadership lessons 31:14 Habits that have helped Shiv You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

0:00 Intro  1:27 Semaglutide (Wegovy) lowdown, use in longevity clinics  6:38 Is a 'pill for everything' a bad thing?  10:39 What's going to happen to all the DTC weight loss startups?  13:37 Is Semaglutide a TikTok conspiracy by big pharma?  14:55 The new alcohol-free alcohol, GABA  21:07 Where are all the big UK healthtech exits?  24:16 US investors/entrepreneurs are more ambitious  27:41 Is DTC digital health the way to go?  32:40 Is there much point building in the UK?   Joined by:  Dr Adam Bataineh: Longevity doctor and Co-founder Span Health (acquired by EightSleep).  Dr Imran Mahmud: Investor, Oxford-trained doctor, ex-Mckinsey and Co-founder of NYE Health.  Dr Mustafa Sultan: Creator of Big Picture Medicine and Doctor.

0:00 Intro  1:09 David Sinclair's New Startup   11:25 ChatGPT for Drug Development  28:32 Transhumanist Gene Editing to Sleep Less  37:38 Banter/Audience Feedback   Dr Adam Bataineh: Longevity doctor and Co-founder Span Health (acquired by EightSleep).  Dr Imran Mahmud: Investor, Oxford-trained doctor, ex-Mckinsey and Co-founder of NYE Health.  Dr Mustafa Sultan: Creator of Big Picture Medicine and Doctor.

Dr Ignacio Medrano is the Founder of Savana (raised $44M dollars with over 100 employees). They use AI to unlock all the value out of clinical records and produce real world evidence. 0:00 Intro 0:34 Ignacio's story 1:30 Learnings from Neurology -> Entrepreneurship 3:27 How to build good health products/services 5:03 Downsides of being a doctor in health entrepreneurship 7:21 Just in case vs just in time learning 9:14 Perils of perfectionism in healthcare 12:34 Do you need to be a d**k to be a good leader? 14:27 Dunbar's number — leading bigger organisations 17:52 Differences in operating in Europe 20:12 Diagnostic medical AI is a waste of time 23:15 SWOT analysis of Savana 26:07 Threats to Savana — LLMs? 29:22 Being eccentric as a competitive advantage 31:09 Becoming a better speaker/storyteller 34:02 Declining Royal Academy of Sciences invite 36:24 Arrogance as a competitive advantage 38:48 Tribes — exclusion criteria importance 40:27 Billion $ Health Idea 41:38 Not watching TV as a competitive advantage 46:40 Outro You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Dr Stephanie Eltz is a Trauma Surgeon and CEO and Co-founder of Doctify, which is basically Yelp/Trustpilot for Doctors. They’ve raised >£22M dollar in funding to date.   0:00 Intro  0:41 Story  2:34 Motivations  3:47 Building Doctify  8:25 Why do you have grit? Early childhood  9:21 Are patient reviews good measures of a doctor?  13:53 There is no growth hack  16:34 How to stop reviews becoming a cesspit  19:48 Monetising  21:15 It's all about the destination  22:46 Happiness as a founder  24:31 Are you full of sh*t?  26:48 First become a King, then a Philosopher  28:10 Leadership and MBTI 29:28 Habits  30:20 Insecurity and immigrant hustle  33:16 Hustling  35:00 You don't need to network  36:17 Outro You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Jason Foster is the CEO of Ori Biotech; a cell and gene therapy company who have raised $139M in funding. He also sits on the boards of companies like GripAble, Credentially, and Auxita — and is an active angel investor. 0:00 Intro  0:34 Jason's story  5:31 What was your goal?  6:39 When did you make it?  8:31 Taking calculated risks in life  10:48 Creating value vs chasing $$  12:15 When should you say no?  16:39 How to coach people  20:53 How to find a coach?  23:37 How to do cold outreach  27:16 Being a marketer and making it in biotech  31:54 Introversion vs extroversion as a CEO/founder  35:37 How to build professional relationships, Neurolinguistic Programming  37:54 The founders first zeitgeist  42:05 Managing your ego  45:07 Disagreeable givers  45:39 Why do media?  46:29 Jason's grand theory  51:59 Why are health/life sciences/biotech unique markets?  55:28 Billion dollar health idea 1  59:57 Billion dollar health idea 2  1:04:00 Money and happiness  1:07:50 Habits that have helped Jason You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Dr Adam Bataineh is a Longevity Doctor and Founder of Span Health (acquired by EightSleep).  0:00 Intro  0:15 Bryan Johnson's Blueprint Program  12:32 Spotify's Daniel Ek Enters Healthcare  22:27 VitaDAO Raises $4.1 (from Pfizer, Balaji Srinivasan...)