Scientific Sense ®

Scientific Sense ® by Gill Eapen: Prof. Leah Krubitzer is professor in the Department of Psychology and Center for Neuroscience at the University of California, Davis.   Her current research focuses on the impact of early experience on the cortical phenotype, and she specifically examines the effects of the sensory environment on the development of connections, functional organization and behavior and seeks to understand how culture impacts brain development.    The Combinatorial Creature: Cortical Phenotypes within and across Lifetimes.    Not all cortical expansions are the same: The coevolution of the neocortex and the dorsal thalamus in mammals  Future of the Brain: Essays by the World’s Leading Neuroscientists   Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Scientific Sense ® by Gill Eapen: Prof Trey Ideker is Professor of Medicine, Bioengineering and Computer Science at the University of California, San Diego. He directs the National Resource for Network Biology, and the Cancer Cell Map and Psychiatric Cell Map Initiatives.   A multi-scale map of cell structure fusing protein images and interactions. Nature. 2021 Nov 24. doi: 10.1038/s41586-021-04115   “We Might Not Know Half of What’s in Our Cells, New AI Technique Reveals  Interpretation of cancer mutations using a multiscale map of protein systems. Science. 2021   A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.   A protein interaction landscape of breast cancer. Science. 2021 Oct;374(6563):eabf3066  “Studies Delve Deep into the Protein Machinery of Cancer Cells.” NCI (4 Nov 2021) “From COVID to cancer, gene-mapping tool could ‘revolutionize’ treatment“. SF Chronicle (2 Oc  “Moonshot Project Aims to Understand and Beat Cancer Using Protein Maps“. Singularity Hub (5 Oct 2021)  “Looking Beyond DNA to See Cancer with New Clarity,”   Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells. Cancer Cell (2020), https://doi.org/10.1016/j.ccell.2020.09.014. PMID: 33096023. [PDF] [PubMed] Related Press: UCSD Health, AZoLifeSciences, Med India, Health IT Analytics and ScienceDaily.   Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome. Cell Systems. 2020 Aug 26;11(2):176-185.e6. doi: 10.1016/j.cels.2020.06.006. Epub 2020 Jul 2. PMID: 32619550 [PDF] [PubMed] *Cover Article  Related Press: Here’s a better way to convert dog years to human years, scientists say. Science Magazine (15 Nov 2019).  See also: Scientific American, BBC, NPR, Washington Post, Discover Magazine, Smithsonian, New York Post, (and more)   Identifying Epistasis in Cancer Genomes: A Delicate Affair. Cell. 2019 May 30;177(6):1375-1383. doi: 10.1016/j.cell.2019.05.005. Review. PMID: 31150618 [PDF] [PubMed]    Using deep learning to model the hierarchical structure and function of a cell.* Nat Methods. 2018 Mar 5. doi: 10.1038/nmeth.4627. PMID: 29505029 [PDF] [PubMed] [Cover Art] *Cover article   Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Scientific Sense ® by Gill Eapen: Alessandro Gavazza is Professor of Economics at the London School of Economics and Research Fellow of the Centre for Economic Policy Research. He is an applied economist, with main interests in industrial organization. His research focuses on the role of frictions in markets.  Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

The Persistent Effects of Decreasing Labor-Market Discrimination, Do Youth Employment Programs Work? Evidence from the New Deal, The association between educational attainment and longevity using individual-level data from the 1940 census, Discrimination and Racial Disparities in Labor Market Outcomes, and The Incentive Effects of Cash Transfers to the Poor   Scientific Sense ® by Gill Eapen: Adriana Lleras-Muney is a Professor of Economics at UCLA. Her research examines the relationships between socio-economic status and health, with a particular focus on education and income.   Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Deep History and the Rhythm of Catastrophe and Merleau-Ponty and the Eco-Literary Imaginary,    Scientific Sense ® by Gill Eapen: Prof. Louise Westling is Professor Emerita of English and Environmental Studies at the University of Oregon. Her research focuses on ecophenomenology and literature, animality, and embodiment in language. A related activity is herding sheep with Australian Kelpies, a good way to learn and develop cross-species communication.   Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

What Is Nuclear Factor Kappa B (NF-κB) Doing in and to the Mitochondrion? Evidence for the Involvement of TNF and NF-kB in Hippocampal Synaptic Plasticity, NF-κB p50 subunit knockout impairs late LTP and alters long term memory in the mouse hippocampus, Early Growth Response 2 (Egr-2) Expression is Triggered by NF-κB Activation, and Chronic dietary creatine enhances hippocampaldependent spatial memory, bioenergetics, and levels of plasticity-related proteins associated with NF-κB    Scientific Sense ® by Gill Eapen: Prof. Benedict C. Albensi is a Professor and Chair of the Department of Pharmaceutical Sciences and the co-director of the BRAIN Center at Nova SouthEastern University. His research interests include factors involved in ageing, cognition, and Alzheimer's disease (AD), such as nuclear factor kappa B (NF-kB), a mediator of inflammation but also a required molecule for memory.    Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

WOMEN AND STEM, Race, Ethnicity, and NIH Research Awards, Reflections on race, ethnicity, and NIH research awards, Gender, Race, and Academic Career Outcomes —Does Economics Mirror Other Disciplines?, Does Mentoring Increase the Collaboration Networks of Female Economists? An Evaluation of the CeMENT Randomized Trial, Women in Academic Economics: Have We Made Progress?, and Association of Mask Mandates and COVID-19 Case Rates, Hospitalizations, and Deaths in Kansas   Scientific Sense ® by Gill Eapen: Prof. Donna Ginther is Professor of Economics and the director of the Institute for Policy and Social Research at the University of Kansas. Her Research Interests include scientific labor markets, gender differences in employment outcomes, wage inequality, scientific entrepreneurship, and children’s educational attainments.    Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Cypin regulates dendrite patterning in hippocampal neurons by promoting microtubule assembly, Structural characterization of the zinc binding domain in cytosolic PSD-95 interactor, The Role of PSD-95 and Cypin in Morphological Changes in Dendrites Following Sublethal NMDA Exposure (cypin): Role of zinc binding in guanine deamination and dendrite branching, and Cypin: A novel target for traumatic brain injury.   Scientific Sense ® by Gill Eapen: Prof. Bonnie Firestein is Professor of Neuroscience at Rutgers University. Her interests include Regulation of dendrite patterning, synaptogenesis, and neural circuitry, with relevance to CNS injury and schizophrenia.    Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Blood and stories: how genomics is rewriting race, medicine and human history, and Replicant Being - Law and Strange Life in the Age of Biotechnology   Scientific Sense ® by Gill Eapen: Prof. Priscilla Wald is Professor of English and Gender Sexuality and feminist Studies at Duke University,  She works on U.S. literature and culture, contemporary narratives of science and medicine, science fiction literature and film, law, and environmental studies.   Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Towards complete and error-free genome assemblies of all vertebrate species, The Earth BioGenome Project 2020: Starting the clock, and Scientific excellence in sequencing all life on Earth depends on justice, equity, diversity and inclusion    Scientific Sense ® by Gill Eapen: Dr. Marcela Uliano-Silva is Senior Bioinformatician at the Wellcome Sanger Institute. Her research interests are (i) mechanisms of genome evolution, (ii) the improvement of genome assembly pipelines and (iii) actions towards inclusion and diversity in science.    Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1