
The Dr. Lee Warren Podcast
Neurosurgeon and award-winning author Dr. W. Lee Warren, MD delivers weekly prescriptions from neuroscience, faith, and common sense on how to lead a healthier, better, happier life. You can’t change your life until you change your mind, and Dr. Warren will teach you the art of self-brain surgery™ to get it done. His latest book, Hope Is the First Dose, is available everywhere books are sold.
Latest episodes

Jun 8, 2025 • 1h 7min
The Origin of Life, with Dr. James Tour (S12E50)
In this episode of the Self-Brain Surgery Podcast, Dr. Lee Warren hosts Dr. James Tour, a world-renowned synthetic chemist and Christian evangelist, to discuss the intersection of faith and science.
Dr. Tour, named one of the top 50 most influential scientists globally, shares insights from his extensive research in chemistry, including advancements in brain and spinal cord injury repair, cancer treatments, and AI technology.
Beyond his scientific achievements, Dr. Tour speaks passionately about his journey from secular Judaism to Christianity, his commitment to evangelism, and the importance of not conflating scientific hypotheses with facts.
The conversation delves into the complexities of life’s origins, challenging the widely taught primordial soup model, and emphasizing that good science often harmonizes with faith. Dr. Tour also extends an open invitation to non-believers for one-on-one discussions to explore the compatibility of science and the Christian faith.
Click here for the transcript
Chapters
00:00 Introduction to Dr. James Tour
00:12 Dr. James Tour's Scientific Achievements
01:08 Dr. Tour's Journey to Christianity
01:32 The Intersection of Science and Faith
03:47 Upcoming Guests and Topics
04:18 Dr. Tour's Perspective on Origin of Life Research
08:06 Dr. Tour's Personal Testimony
13:03 Challenges and Persecutions
14:55 Dr. Tour's Scientific Contributions and Innovations
21:11 Complexities of Chemical Reactions and Life Formation
28:49 The Complexity of Assembling Life
30:44 The Miller-Urey Experiment Revisited
32:09 Challenges in Origin of Life Theories
36:54 The RNA World Hypothesis
40:12 Faith and Science: A Harmonious Relationship
50:40 The Passion for Evangelism
56:54 Final Thoughts and Invitation
Resources and Links
Dr. Tour's YouTube Channel
Dr. Tour will meet with you to discuss Jesus if you're not a believer
Dr. Tour's website (links to all his social media)
Dr. Tour on Instagram
My book, 2021 ECPA Memoir/Biography of the Year, I've Seen the End of You
Be sure to check out my latest book, Hope Is the First Dose!
Sign up for my weekly Self-Brain Surgery Newsletter here! (Get my free Thought Biopsy Worksheet when you subscribe!) Learn more about your ad choices. Visit megaphone.fm/adchoices

Jun 6, 2025 • 28min
The Devil is a Cognitive Neuroscientist (S12E49)
In this powerful episode of the Self-Brain Surgery podcast, Dr. Lee Warren discusses the overarching mission of his show, which combines neuroscience and faith to transform lives.
Dr. Warren explains the concept of 'resistance' (inspired by Steven Pressfield) as a force that inhibits personal growth, drawing parallels to the devil from a spiritual perspective. He explores the difference between the brain and the mind, the significance of mental resilience, and the practical application of scientific and theological principles to overcome life's challenges.
Sharing stories of personal hardships and recoveries, Dr. Warren encourages listeners to understand the power of changing their mind to change their life.
Click here for the transcript
Chapters
Introduction and Podcast Mission
Understanding Resistance and the Devil's Role
Personal Stories of Overcoming Hardship
The Power of Neuroscience and Faith
Applying Neuroscience to Daily Life
Upcoming Episodes and Final Thoughts
Want more tools for rewiring your brain and renewing your mind?
🎙️ Subscribe to The Self-Brain Surgery with Dr. Lee Warren Podcast for weekly strategies to change your brain—and your life.📖 Grab my book Hope Is the First Dose for a roadmap to recovery and transformation.📘 And stay tuned for The Life-Changing Art of Self-Brain Surgery—coming February 2026! Learn more about your ad choices. Visit megaphone.fm/adchoices

Jun 2, 2025 • 60min
The Immortal Mind, with Dr. Michael Egnor (S12E48)
In this episode of the Self Brain Surgery Podcast, Dr. Lee Warren welcomes neurosurgeon Dr. Michael Egnor (written with Denyse O'Leary), who discusses his new book, The Immortal Mind: A Neurosurgeon's Case for The Existence of the Soul.
Dr. Egnor shares his journey from atheism to faith, emphasizing the distinction between the mind and the brain. They delve into scientific evidence, including functional MRI studies and split-brain research, that suggests a non-material aspect of the mind. Additionally, Dr. Egnor shares personal anecdotes and philosophical insights that support the concept of an immortal soul. The episode underscores the significance of understanding the mind-brain relationship for finding hope and purpose in life.
Click here for the transcript
Chapters
00:00 Introduction and Guest Introduction
00:16 Exploring the Mind-Brain Relationship
00:31 The Immortal Mind: Book Overview
00:42 Hope and Meaning Beyond Life's Challenges
00:59 Deep Dive into Neuroscience and the Soul
01:08 Book Giveaway Announcement
01:43 Interview Begins: Welcoming Dr. Michael Egnor
02:52 Dr. Egnor's Journey from Atheism to Faith
06:27 Challenging Materialism and Atheism
15:59 The Concept of Free Will
18:18 Defining the Soul and Its Significance
21:53 Mind, Brain, and Soul: Neurosurgical Insights
27:00 The Brain's Mysteries: Neuroscience Insights
27:31 Split Brain Surgery: Unveiling the Mind's Secrets
30:28 Twins Joined at the Brain: A Unique Connection
32:26 Persistent Vegetative State: New Discoveries
36:58 The Immortal Soul: Science and Faith
43:37 The Mind-Brain Connection: Quantum Mechanics and Philosophy
47:49 Conclusion: Changing Your Mind, Changing Your Life
Resources and Links:
Dr. Egnor's book
Dr. Egnor's writing with the Discovery Institute
Great interview between Dr. Egnor and Robery Marks
🎙️ Subscribe to The Self-Brain Surgery with Dr. Lee Warren Podcast for weekly strategies to change your brain and life.
📖 Grab my book Hope Is the First Dose. Learn more about your ad choices. Visit megaphone.fm/adchoices

May 30, 2025 • 53min
A Conversation with Rick Burgess (S12E47)
In this episode, Dr. Lee Warren welcomes Rick Burgess, New York Times bestselling author and celebrated radio host (Rick and Bubba, The Rick Burgess Show), who shares invaluable life lessons and stories from his new book, Men Don't Run in the Rain.
Rick talks about his father's enduring influence as a legendary Alabama football coach, his own journey through personal and professional highs and lows, and how faith and resilience shape his life's mission.
Click here for the transcript
Chapters
00:00 Introduction and Episode Overview
00:24 Meet Rick Burgess: A Life in Radio and Ministry
01:08 Rick's New Book: Men Don't Run In the Rain
07:26 Rick's Father's Legacy
11:18 Lessons from Rick's Father
14:45 Honoring Your Parents: A Biblical Perspective
18:56 Stories and Lessons from Rick's Life
24:55 A Father's Legacy: Fired and Honored
27:15 Battling Alzheimer's: A Coach's Resilience
30:12 The Impact of a Coach: Stories of Influence
34:25 A Son's Grief: Losing a Child
35:52 Faith and Strength: Speaking at a Funeral
40:13 Continuing the Legacy: Writing and Teaching
43:54 Final Thoughts and Resources
Resources and Links
Rick's new book, Men Don't Run in the Rain
Rick's website for The Rick Burgess Show
The Man Church Conference
Sherri Burgess' beautiful book about losing their son Bronner
My book, 2021 ECPA Memoir/Biography of the Year, I've Seen the End of You
Be sure to check out my latest book, Hope Is the First Dose!
Sign up for my weekly Self-Brain Surgery Newsletter here! (Get my free Thought Biopsy Worksheet when you subscribe!) Learn more about your ad choices. Visit megaphone.fm/adchoices

May 26, 2025 • 53min
Overcoming Sex Addiction & Rebuilding Trust: Matthew & Joanna Raabsmith (S12E46)
Overcoming Sexual Addiction & Rebuilding Trust: A Journey with Matthew & Joanna Raabsmith
In this episode of the Self-Brain Surgery podcast, Dr. Lee Warren delves into a sensitive yet critical topic—sexual addiction, infidelity, and pornography.
Featuring Matthew and Joanna Raabsmith, professional therapists specializing in sexual addiction and betrayal trauma from Memphis, TN, the conversation explores their personal story of brokenness and redemption.
The Raabsmiths share insights into how neuroplasticity and God's grace helped them rebuild their marriage and family, offering hope and actionable advice for listeners dealing with similar issues.
The episode includes a discussion on the neuroscience of addiction, the impact on relationships, and pastoral encouragement for those seeking recovery. The Raabsmiths also provide resources and practical steps for couples to reignite trust and intimacy.
Click here for the transcript!
Chapters
00:00 Introduction and Content Warning
00:39 Meet the Guests: Matthew and Joanna Raabsmith
02:17 The Raabsmiths' Journey: From Brokenness to Healing
06:16 Understanding Sexual Addiction and Betrayal Trauma
13:19 The Role of Faith in Recovery
16:46 Challenges of Pornography Addiction
21:40 Advice for Parents: Preventing and Addressing Addiction
24:25 Creating a Safe Space for Kids
25:27 Navigating Relationship Challenges
26:31 The Journey of Healing and Honesty
29:40 Building Trust and Vulnerability
31:11 Finding Purpose in Recovery
35:05 Helping Others Through Your Story
41:35 Encouragement for Those Struggling
45:39 Resources and Final Thoughts
Resources and Links:
The Raabsmith's Website
Free HONEST check in guide/challenge: raabsmithteam.com/free
The Raabsmith's book, Building True Intimacy: Creating a Connection That Stands the Test of Time
Subscribe to Self-Brain Surgery, my free weekly prescription for human flourishing, in the top 35 science publications on Substack!
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May 23, 2025 • 45min
A Super Molecule for Your Health, with David Roberts (S12E45)
In this episode of the Self-Brain Surgery Podcast, Dr. Lee Warren introduces a Science Spotlight special focused on the molecule sulforaphane, known for its anti-inflammatory and anti-cancer properties.
Dr. Warren interviews David Roberts from Mara Labs, who shares the sad but inspiring story of how the company was founded and the journey of creating a stabilized form of sulforaphane.
They discuss the benefits of sulforaphane, including detoxification, brain health, and pain reduction, and delve into Mara Labs' mission to improve lives through scientifically backed supplements. Additionally, the episode touches on the integration of science and faith.
Click here for the transcript
Chapters
00:00 Welcome to the Self Brain Surgery Podcast
00:06 Introduction to Sulforaphane
01:45 Science Spotlight Series Overview
03:31 The Intersection of Science and Faith
05:19 Introducing David Roberts and Mara Labs
05:50 David's Journey and the Birth of Mara Labs
10:01 The Benefits and Science of Sulforaphane
11:08 Challenges and Innovations in Sulforaphane Production
16:50 Detoxification and Health Benefits
19:25 Personal Experiences and Product Development
22:00 The Long-Lasting Effects of Sulforaphane
22:23 Personal Stories and Experiences with Sulforaphane
23:21 Listener Questions and Broccoli Benefits
24:12 The Science Behind Sulforaphane's Quick Effects
25:12 Pain Relief and Anti-Inflammatory Benefits
26:07 BDNF and Vivid Dreams
27:01 The Importance of Tangible Health Improvements
27:39 Mara Labs' Product Innovations
29:24 Challenges and Solutions in Supplement Bioavailability
37:04 Faith and Science in Business
38:33 Conclusion and Special Offers
Resources and Links
Get 15% off your Mara Labs Order and learn more here!
Sign up for my weekly Self-Brain Surgery Newsletter here!
Be sure to check out my latest book, Hope Is the First Dose!
Email questions or comments to contact@drleewarren.com (just copy that address and use it in your mail program to reach us) Learn more about your ad choices. Visit megaphone.fm/adchoices

May 19, 2025 • 42min
Jon Seidl: Confessions of a Christian Alcoholic, Part 1 (S12E44)
In this episode of The Self Brain Surgery Podcast, Dr. Lee Warren interviews Jon Seidl, author of the upcoming book, Confessions of a Christian Alcoholic, (click the link to pre-order). Jon shares his deeply personal journey from battling alcoholism despite being a Christian to finding solace and redemption through faith.
They discuss the importance of trauma therapy, radical vulnerability, and reordering one’s life around Christ. Their conversation emphasizes the transformative power of abiding in Christ and finding one's true identity.
Jon’s story and practical steps offer hope and guidance for anyone struggling with addiction, grief, or any form of suffering.
Click here for the transcript
Chapters
00:00 Introduction and Guest Announcement
02:03 Technical Difficulties and Prayer
02:53 Jon Seidl's Journey and First Book
04:56 Challenges and Realizations
08:43 Hitting Rock Bottom
14:22 Path to Recovery and New Book
19:28 The Importance of Repentance and Grace
20:33 The Struggle with Sin and Finding Jesus
22:32 The Role of Identity in Recovery
24:11 The Dangers of Idolatry in Recovery
26:48 Finding Abundance Through Christ
31:28 The Power of Abiding in Christ
34:41 Final Thoughts and Encouragement
Resources and Links
Jon's first book, Finding Rest: A Survivor's Guide to Navigating the Valleys of Anxiety, Faith, and Life
Jon Seidl's website
Click here to subscribe to Jon's powerful, daily writing on Substack
Follow Jon on Instagram
Sign up for my weekly Self-Brain Surgery Newsletter here!
Learn more about your ad choices. Visit megaphone.fm/adchoices

May 16, 2025 • 45min
Five Mere Christians with Jordan Raynor (S12E43)
In this episode of the Self-Brain Surgery Podcast, Dr. Lee Warren discusses the meaning and purpose of our work with special guest, Jordan Raynor.
Jordan, a serial entrepreneur and bestselling author, shares insights from his new book, Five Mere Christians, which profiles five ordinary individuals whose seemingly secular work transformed the world.
The episode includes powerful stories of Fred Rogers, Fannie Lou Hamer, Ole Kirk Christiansen, Hannah More, and C.S. Lewis, exploring themes of perseverance, faith, and the sacredness of everyday work.
Jordan and Dr. Warren also discuss how personal trials and societal challenges can be overcome through faith and how everyone’s work can have a profound impact. The conversation underscores the importance of recognizing the spiritual significance of all vocations and prompts listeners to reflect on their own work's potential to serve God's kingdom.
Click here for the transcript
Chapters
00:00 Introduction and Special Guest Announcement
01:14 Meet Jordan Raynor
03:35 The Sacredness of Secular Work
03:49 Jordan's Journey and Insights
07:02 Introduction to 'Five Mere Christians'
10:19 Fannie Lou Hamer's Story
13:44 Ole Kirk Christiansen's Story
16:08 Hannah More's Story
19:23 The Hidden Growth of Faith
19:34 Unveiling the Real C.S. Lewis
20:43 The Power of Mere Christians
23:00 Personal Stories of Calling and Faith
25:23 Fred Rogers' Unique Ministry
28:30 Finding Holy Ground in Our Work
31:06 Encouragement for the Hurting
35:23 Final Thoughts and Takeaways
Resources and Links
Jordan's website
(I highly recommend Jordan's newsletter, The Word Before Work, which is read by over 100,000 people weekly! You can sign up for free on his website.)
Get a free chapter of Five Mere Christians by clicking here
Sign up for my weekly Self-Brain Surgery Newsletter here!
Be sure to check out my latest book, Hope Is the First Dose!
Email questions or comments to contact@drleewarren.com (just copy that address and use it in your mail program to reach us) Learn more about your ad choices. Visit megaphone.fm/adchoices

May 12, 2025 • 57min
Dr. Stephen Meyer: Following Science Back to Faith (S12E42)
In this episode of the Self Brain Surgery Podcast, I have an inspiring conversation with Dr. Stephen Meyer, a world-renowned scientist and one of the founders of Intelligent Design.
We explore life's big questions regarding purpose and meaning, critiquing the materialistic view that life is merely a product of random processes. Dr. Meyer, with his extensive background in both geophysics and the philosophy of science, shares insights from his work, particularly his books Signature in the Cell, Darwin's Doubt, and The Return of the God Hypothesis.
We discuss how intelligent design offers a compelling explanation for the information-rich structures of life, countering traditional Darwinian evolution and the prevailing conflicts between science and faith. This episode aims to bridge the gap between science and theology, providing listeners with a hopeful perspective that integrates both fields.
Click here for the transcript.
Chapters
00:00 Introduction and Guest Overview
00:43 The Philosophy of Materialism and Its Limitations
03:08 Introducing Dr. Stephen Meyer
07:05 Stephen Meyer's Journey and Work
10:05 The Origin of Life and Intelligent Design
16:29 Challenges to Darwinian Evolution
35:26 The Cambrian Explosion and Fossil Record
43:54 The Intersection of Science and Faith
50:00 Conclusion and Final Thoughts
Resources and Links
Dr. Meyer's website
Sign up for my weekly Self-Brain Surgery Newsletter here!
Our featured partner for this episode is Zuma Nutrition. Click this link, and checkout with the promo code DRLEEWARREN to get 15% off.
Learn more about your ad choices. Visit megaphone.fm/adchoices

May 9, 2025 • 35min
Dr. Gena Nikitin: Precision Medicine and What Science is For (S12E41)
In this special science spotlight episode of the Self Brain Surgery podcast, renowned neurosurgeon and author Dr. Lee Warren is joined by Dr. Gena Nikitin, a Russian-born biochemist living in Norway.
Dr. Nikitin discusses his company Miphic and its focus on precision medicine, which aims to tailor medical treatments based on an individual's unique biochemical profile. The conversation delves into the importance of mitochondria, the cellular batteries that drive energy production, and how understanding their function can revolutionize treatments for diseases like cancer and autoimmune disorders.
Dr. Nikitin also shares his philosophical views on science and faith, emphasizing that science is a tool for becoming less wrong over time rather than discovering absolute truth. This episode highlights the potential for significant advancements in personalized medicine and the moral drive behind scientific discovery.
Chapters
00:00 Introduction and Episode Overview
01:51 Meet Dr. Gena Nikitin: A Journey from Russia to Norway
02:34 Precision Medicine and Mitochondria
03:04 Gena's Scientific Journey and Passion for Biochemistry
07:46 The Role of Mitochondria in Health and Disease
09:50 Innovations in Mitochondrial Testing
14:03 The Future of Precision Medicine
16:21 Science, Faith, and Personal Resilience
26:17 Concluding Thoughts and Future Conversations
Resources and Links
Click here for the transcript
Learn more about Miphic here
Follow Dr. Nikitin on LinkedIn
Be sure to check out my latest book, Hope Is the First Dose!
Sign up for my weekly Self-Brain Surgery Newsletter here! Learn more about your ad choices. Visit megaphone.fm/adchoices