Comedian Andy Hendrickson (@andyhendrickson) joins Jesse, Matt and Andy to talk about magic tricks that only work on monkeys with opposable thumbs, how mirrors know where eggs are, a math formula for achieving orgasm, how quickly you can create false memories and Andy's neighbor Tony's commentary track on Birdemic 3.

Comedian Nate Craig (@hypeman) returns to the podcast to talk about a deadly fungal infection, terrible maps, building cities on shaky ground, the history of plate tectonics, nanoplastics interfering with chicken embryos and a 3D-printed cake.

Comedian Noman Hosni (@NomanHosni) joins Matt, Jesse and Andy to talk about Tunisia, bad fan art, hair transplants, a bad embryo swap, Paris' City of Science and Industry, a blood test for anxiety, storing carbon dioxide in the ocean as baking soda, how much lift the space shuttle lander can generate and mapping the brain of a fruit fly.

Host of Daily Tech News Show Sarah Lane (@sarahlane) joins Jesse, Matt and Andy to talk about ballerina doppelgangers, Tom Cruise stunts, Cocaine Bear, accidentally ending up on the air, bumblebees learning to solve puzzles by watching their friends, talkin' transoms, more medical tourism, Meta's VR play and DuckDuckGo's new AI-assisted search.

New York Times technology columnist and host of the Hard Fork podcast Kevin Roose (@kevinroose) joins Andy, Jesse and Matt to talk about his infamous, amorous encounter with Bing Chat/Sydney, Sydney's response to his story, getting backhanded compliments from John Oliver, how ChatGPT was dismissed by its own creators, generative AI and the future of deepfakes, AI's capability overhang, explaining LLMs' weirdness with the Waluigi effect, artists' lawsuits over training AI on their creations, whether we care how art is made, which jobs could soon be on the chopping block and Futureproof, Kevin's handbook for the weird times ahead.

Comedian and writer Amanda Brooke Perrin (@brookeperrin) joins Matt, Andy and Jesse to discuss haboobs, a Tony update, a 2200-year-old flush toilet found in China, DIY Poo-Pourri, how soft food gave us the F-word, Andy's consonant invention, ChatGPT developing a theory of mind, and dolphin handjobs.

Comedian Erica Spera (@Spericaa) joins Andy, Jesse and Matt to talk about almost going into dentistry, prehistoric teeth, Andy's Mexican dental tourism, what we're supposed to call mummies now, monster cereals, AI Seinfeld's heel turn, Roko's basilisk, mummy chemicals, ancient stone tools and more stone tools and Soylent.

Comedian/filmmaker Jo Rou (@awkwardlyjazzy) joins Jesse, Matt and Andy to discuss Santana's answer to Beats by Dre, the mystery of a gibbon immaculate conception solved, the tiny radioactive capsule that went missing in the outback, detecting cancer with customer loyalty cards, airbrushing Boris Johnson, Jesse's bad business ideas, the Snickers dick vein, World War I talk, the awful new show Power Slap and Jo's sitcom I Adore Dolores.

Clinical psychologist and misophonia researcher Dr. Jane Gregory (@drjanegregory) and comedian Steve Hall (@astevehall) return to the show to talk with Matt, Jesse and Andy about Jane's work studying misophonia, what to do if your spouse's breathing drives you insane, and what's on the horizon for treating the condition. Trigger non-warning: This episode contains NO examples of misophonia-triggering sounds. That we know of.

Comedian, goalkeeper and coach Michael Magid (@michaelmagid) joins Andy, Matt and Jesse to discuss Michael's football (soccer) podcast Inside the 18, his new social network The Union, quitting your gym with the help of AI, a Tesla that caused a pileup, a Tesla that thwarted a triple murder-suicide, fires in electric vs. gas cars, a breakthrough in reversing aging in mice, ripped old guys, Matt Braunger's Weight Smashers sketch, lab-grown retinal eye cells to treat blindness and Matt and Andy's new favorite podcast If Books Could Kill.